Melampolides from Argentinean Acanthospermum australe
The investigation of the ethanol extract of Acanthospermum australe, collected in the province of Misiones, Argentina, yielded eight melampolides (1-8) of the acanthospermal type. Two of them, 8β-hydroxy-9α-(2-methylbutyryloxy)-14-oxo-acanthospermolide (3) and 9α-hydroxy-8β-(2-methylbutyryloxy)-14-o...
Guardado en:
| Autor principal: | |
|---|---|
| Otros Autores: | , , |
| Formato: | Capítulo de libro |
| Lenguaje: | Inglés |
| Publicado: |
2009
|
| Materias: | |
| Acceso en línea: | Registro en Scopus DOI Handle Registro en la Biblioteca Digital |
| Aporte de: | Registro referencial: Solicitar el recurso aquí |
| LEADER | 05738caa a22007577a 4500 | ||
|---|---|---|---|
| 001 | PAPER-8557 | ||
| 003 | AR-BaUEN | ||
| 005 | 20230518203821.0 | ||
| 008 | 190411s2009 xx ||||fo|||| 00| 0 eng|d | ||
| 024 | 7 | |2 scopus |a 2-s2.0-67650859638 | |
| 040 | |a Scopus |b spa |c AR-BaUEN |d AR-BaUEN | ||
| 100 | 1 | |a Sánchez, M. | |
| 245 | 1 | 0 | |a Melampolides from Argentinean Acanthospermum australe |
| 260 | |c 2009 | ||
| 270 | 1 | 0 | |m Palermo, J.A.; UMYMFOR, Departamento de Química Orgánica, Facultad de Ciencias Exactas y Naturales, Ciudad Universitaria, Pabellon 2, 1428 Buenos Aires, Argentina; email: palermo@qo.fcen.uba.ar |
| 506 | |2 openaire |e Política editorial | ||
| 504 | |a Bohlmann, F., Jakupovic, J., Zdero, C., King, R.M., Robinson, H., Neue Melampolide und cis,cis-Germacranolide aus Vertretern der Subtribus Melampodiinae (1979) Phytochemistry, 18, pp. 625-630 | ||
| 504 | |a Bohlmann, F., Jakupovic, J., Dhar, A.K., King, R.M., Robinson, H., Two sesquiterpene and three diterpene lactones from Acanthospermum australe (1981) Phytochemistry, 20, pp. 1081-1083 | ||
| 504 | |a Bohlmann, F., Schmeda-Hirschmann, G., Jakupovic, J., New melampolides from Acanthospermum australe (1984) Planta Med., 50, pp. 37-39 | ||
| 504 | |a Debenedetti, S., Martino, V., Palacios, P., Coussio, J.D., 6-Methoxyflavonoids from Acanthospermum Australe (1987) J. Nat. Prod., 50, pp. 325-1325 | ||
| 504 | |a Herz, W., Kalyanaraman, P.S., Acanthospermal A and Acanthospermal B, two new melampolides from Acanthospermum species (1975) J. Org. Chem., 40, pp. 3486-3491 | ||
| 504 | |a Matsunaga, K., Sayito, M., Ohizumi, Y., Acanthostral, a novel antineoplastic cis-cis-cis-germacranolide from Acanthospermum australe (1996) Tetrahedron Lett., 37, pp. 1455-1456 | ||
| 504 | |a Saleh, A.A., Cordell, G.A., Farnsworth, N.R., Potential anticancer agents. Part 13. Cytotoxic constituents of Acanthospermum glabratum (Asteraceae) (1980) J. Chem. Soc. Perkin Trans., 1 (5), pp. 1090-1097 | ||
| 504 | |a Seaman, F.C., Fischer, N.H., Stuessy, T.F., Systematic implications of sesquiterpene lactones in the subtribe melampodiinae (1980) Biochem. Syst. Ecol., 8, pp. 263-271 | ||
| 504 | |a Xiang, Y., Fan, C.Q., Yue, J.M., Novel sesquiterpenoids from Siegesbeckia orientalis (2005) Helv. Chim. Acta, 88, pp. 160-170 | ||
| 520 | 3 | |a The investigation of the ethanol extract of Acanthospermum australe, collected in the province of Misiones, Argentina, yielded eight melampolides (1-8) of the acanthospermal type. Two of them, 8β-hydroxy-9α-(2-methylbutyryloxy)-14-oxo-acanthospermolide (3) and 9α-hydroxy-8β-(2-methylbutyryloxy)-14-oxo-acanthospermolide (7) are new compounds. Two other compounds (4 and 8) have been previously reported, and the NMR data of 4 are corrected. Compounds 1, 2, 5 and 6 have not been previously reported, but are probably artifacts formed during extraction. Compounds 3, 6 and 7 showed slight antibiotic activity against Gram-positive bacteria. © 2009 Phytochemical Society of Europe. |l eng | |
| 536 | |a Detalles de la financiación: Umweltbundesamt | ||
| 536 | |a Detalles de la financiación: Agencia Nacional de Promoción Científica y Tecnológica, PICT, 14321 | ||
| 536 | |a Detalles de la financiación: Consejo Nacional de Investigaciones Científicas y Técnicas, PEI 6478 | ||
| 536 | |a Detalles de la financiación: This research was supported by grants from CONICET (PEI 6478), UBA (X 260 Programación 2004–2007) and ANPCyT (PICT (2003) 14321). We thank Mr. José Gallardo and Lic. Gernot Eskuche (UMYMFOR–CONICET) for recording some of the NMR spectra. M. Sánchez thanks CONICET for a postdoctoral fellowship. Appendix A | ||
| 593 | |a UMYMFOR, Departamento de Química Orgánica, Facultad de Ciencias Exactas y Naturales, Ciudad Universitaria, Pabellon 2, 1428 Buenos Aires, Argentina | ||
| 593 | |a Departamentos de Farmacia y Microbiología, Facultad de Ciencias Exactas, Químicas y Naturales, Univ. Nacional de Misiones, Av. Mariano Moreno 1375, 3300 Posadas, Misiones, Argentina | ||
| 690 | 1 | 0 | |a ACANTHOSPERMOLIDES |
| 690 | 1 | 0 | |a ACANTHOSPERMUM AUSTRALE |
| 690 | 1 | 0 | |a MELAMPOLIDES |
| 690 | 1 | 0 | |a SESQUITERPENE LACTONES |
| 690 | 1 | 0 | |a 8BETA HYDROXY 9ALPHA (2 METHYLBUTYRYLOXY) 14 OXO ACANTHOSPERMOLIDE |
| 690 | 1 | 0 | |a 9ALPHA HYDROXY 8BETA (2 METHYLBUTYRYLOXY) 14 OXO ACANTHOSPERMOLIDE |
| 690 | 1 | 0 | |a ACANTHOSPERMUM AUSTRALE EXTRACT |
| 690 | 1 | 0 | |a MELAMPOLIDE |
| 690 | 1 | 0 | |a PLANT EXTRACT |
| 690 | 1 | 0 | |a UNCLASSIFIED DRUG |
| 690 | 1 | 0 | |a ACANTHOSPERMUM AUSTRALE |
| 690 | 1 | 0 | |a ANTIMICROBIAL ACTIVITY |
| 690 | 1 | 0 | |a ARTICLE |
| 690 | 1 | 0 | |a ARTIFACT |
| 690 | 1 | 0 | |a DRUG ISOLATION |
| 690 | 1 | 0 | |a DRUG STRUCTURE |
| 690 | 1 | 0 | |a GRAM POSITIVE BACTERIUM |
| 690 | 1 | 0 | |a NUCLEAR MAGNETIC RESONANCE |
| 690 | 1 | 0 | |a PRIORITY JOURNAL |
| 690 | 1 | 0 | |a SHRUB |
| 690 | 1 | 0 | |a ACANTHOSPERMUM AUSTRALE |
| 690 | 1 | 0 | |a POSIBACTERIA |
| 651 | 4 | |a ARGENTINA | |
| 700 | 1 | |a Kramer, F. | |
| 700 | 1 | |a Bargardi, S. | |
| 700 | 1 | |a Palermo, J.A. | |
| 773 | 0 | |d 2009 |g v. 2 |h pp. 93-95 |k n. 3 |p Phytochem. Lett. |x 18743900 |t Phytochemistry Letters | |
| 856 | 4 | 1 | |u https://www.scopus.com/inward/record.uri?eid=2-s2.0-67650859638&doi=10.1016%2fj.phytol.2008.12.007&partnerID=40&md5=d5918dc03cccc6a3bba228c2a8f5c3ba |y Registro en Scopus |
| 856 | 4 | 0 | |u https://doi.org/10.1016/j.phytol.2008.12.007 |y DOI |
| 856 | 4 | 0 | |u https://hdl.handle.net/20.500.12110/paper_18743900_v2_n3_p93_Sanchez |y Handle |
| 856 | 4 | 0 | |u https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_18743900_v2_n3_p93_Sanchez |y Registro en la Biblioteca Digital |
| 961 | |a paper_18743900_v2_n3_p93_Sanchez |b paper |c PE | ||
| 962 | |a info:eu-repo/semantics/article |a info:ar-repo/semantics/artículo |b info:eu-repo/semantics/publishedVersion | ||
| 999 | |c 69510 | ||