Effect of estradiol and tamoxifen on the anchorage-independent growth of the subpopulations derived from MCF-7 breast carcinoma cells: Cytogenetic analysis of the stem cell subpopulation
The MCF-7 breast carcinoma cell line can be separated by Percoll density gradient centrifugation into several subpopulations, A to F, one of which (E) has been previously suggested to be highly enriched in stem cells. The anchorage-independent growth of the different fractions and its sensitivity to...
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| Otros Autores: | , , , , , |
| Formato: | Capítulo de libro |
| Lenguaje: | Inglés |
| Publicado: |
1988
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| Acceso en línea: | Registro en Scopus DOI Handle Registro en la Biblioteca Digital |
| Aporte de: | Registro referencial: Solicitar el recurso aquí |
| LEADER | 06180caa a22009497a 4500 | ||
|---|---|---|---|
| 001 | PAPER-778 | ||
| 003 | AR-BaUEN | ||
| 005 | 20230518203006.0 | ||
| 008 | 190411s1988 xx ||||fo|||| 00| 0 eng|d | ||
| 024 | 7 | |2 scopus |a 2-s2.0-0023700205 | |
| 024 | 7 | |2 cas |a estradiol, 50-28-2; tamoxifen, 10540-29-1; Estradiol, 50-28-2; Genetic Markers; Tamoxifen, 10540-29-1 | |
| 040 | |a Scopus |b spa |c AR-BaUEN |d AR-BaUEN | ||
| 030 | |a ECREA | ||
| 100 | 1 | |a Podhajcer, O.L. | |
| 245 | 1 | 0 | |a Effect of estradiol and tamoxifen on the anchorage-independent growth of the subpopulations derived from MCF-7 breast carcinoma cells: Cytogenetic analysis of the stem cell subpopulation |
| 260 | |c 1988 | ||
| 270 | 1 | 0 | |m Mordoh, J.; Instituto de Investigaciones Bioquímicas Fundación Campomar, Antonio Machado 151, 1405 Buenos Aires, Argentina |
| 506 | |2 openaire |e Política editorial | ||
| 504 | |a Buick, Pollack, (1984) Cancer Res, 44, pp. 4909-4918 | ||
| 504 | |a Resnicoff, Medrano, Podhajcer, Bravo, Bover, Mordoh, (1987) Proc. Natl. Acad. Sci. USA, 84, pp. 7295-7299 | ||
| 504 | |a Suele, Vazquez, Long, Alberty, Brennan, (1973) J. Natl. Cancer Inst, 51, pp. 1409-1415 | ||
| 504 | |a Barkley Butter, Berlinski, Hillman, Kelsey, Toenniges, (1986) Cancer Res, 46, pp. 6339-6348 | ||
| 504 | |a Yang, Soule, McGrath, (1977) J. Natl. Cancer Inst, 59, pp. 1357-1367 | ||
| 504 | |a Shin, Freedman, Risser, Pollack, (1975) Proc. Natl. Acad. Sci. USA, 72, pp. 4435-4439 | ||
| 504 | |a Kahn, Shin, (1979) J. Cell Biol, 82, pp. 1-16 | ||
| 504 | |a Smith, (1979) J. Natl. Cancer Inst, 62, pp. 225-230 | ||
| 504 | |a Hamburger, Salmon, (1977) Science, 197, pp. 461-463 | ||
| 504 | |a Seabright, (1971) Lancet, 2, pp. 971-972 | ||
| 504 | |a ISCN, An International System for Human Cytogenetic Nomenclature (1978) (1978) Birth Defects: Original Article Series, 14. , The National Foundation, New York, No. 8 | ||
| 504 | |a ISCN, (1978) Cytogenetic and Genome Research, 21, pp. 309-404. , also in | ||
| 504 | |a Medrano, E. E., Resnicoff, M., Larcher, F., Cafferata, E. G. A., Podhajcer, O., Bover, L., and Molinari, B. Submitted for publication; Whang-Peng, Lee, Kao-Shan, Seibert, Lippman, (1983) J. Natl. Cancer Inst, 71, pp. 687-695 | ||
| 504 | |a Human Gene Mapping 8 (1985) Eight International Workshop on Human Gene Mapping, 40, pp. 1-4. , 2nd ed., Cytogenet. Cell Genet | ||
| 504 | |a Podhajcer, Bravo, Sorin, Guman, Cerdeiro, Mordoh, (1986) Cancer, 58, pp. 720-729 | ||
| 520 | 3 | |a The MCF-7 breast carcinoma cell line can be separated by Percoll density gradient centrifugation into several subpopulations, A to F, one of which (E) has been previously suggested to be highly enriched in stem cells. The anchorage-independent growth of the different fractions and its sensitivity to estradiol (E2) and tamoxifen (TAM) was assayed. The anchorage-independent growth capacity of the different fractions was E>A>B> D>C,F. The E fraction had the highest clonogenic index (6.62 ± 1.18) and was unaffected by E2 or TAM. The karyotypic analysis of the E fraction revealed features similar to those of the unfractionated cell line. It is suggested that the high growth rate of fraction E is due to an enrichment in stem cells and not to the existence of a different clone. © 1988. |l eng | |
| 536 | |a Detalles de la financiación: Universidad de Buenos Aires | ||
| 536 | |a Detalles de la financiación: Universidad Nacional del Centro de la Provincia de Buenos Aires | ||
| 536 | |a Detalles de la financiación: Centro de Investigación en Computación | ||
| 536 | |a Detalles de la financiación: This work has been supported by Grants from the Consejo National de Investigaciones Cientificas y Tecnicas (CONICET), the University of Buenos Aires and the Comisi6n de Investigaciones Cientilicas de la Provincia de Buenos Aires (CIC). L. B., E. E. M., I. L., I. S. and J. M. are members of the CONICET, 0. L. P. is member of the CIC, and M. R. is a Fellow of the Fundaci6n Maria Calderon de la Barca. | ||
| 593 | |a Hospital Mariano R. Castex, Balcarce 900, 1650 San Martin, Provincia de Buenos Aires, Argentina | ||
| 593 | |a Instituto de Investigaciones Bioquímicas Fundación Campomar, Antonio Machado 151, 1405 Buenos Aires, Argentina | ||
| 593 | |a Facultad de Ciencias Exactas y Naturales, Universidad Nacional de Buenos Aires, Argentina | ||
| 593 | |a Academia Nacional de Medicina, Coronel Diaz, 2497, 1425 Buenos Aires, Argentina | ||
| 690 | 1 | 0 | |a ESTRADIOL |
| 690 | 1 | 0 | |a TAMOXIFEN |
| 690 | 1 | 0 | |a ANCHORAGE INDEPENDENT GROWTH |
| 690 | 1 | 0 | |a CELL CULTURE |
| 690 | 1 | 0 | |a CELL GROWTH |
| 690 | 1 | 0 | |a CELL STRAIN MCF 7 |
| 690 | 1 | 0 | |a CONTROLLED STUDY |
| 690 | 1 | 0 | |a CYTOLOGY |
| 690 | 1 | 0 | |a FEMALE |
| 690 | 1 | 0 | |a HUMAN |
| 690 | 1 | 0 | |a HUMAN CELL |
| 690 | 1 | 0 | |a KARYOTYPING |
| 690 | 1 | 0 | |a PRIORITY JOURNAL |
| 690 | 1 | 0 | |a STEM CELL |
| 690 | 1 | 0 | |a ULTRASTRUCTURE |
| 690 | 1 | 0 | |a BREAST NEOPLASMS |
| 690 | 1 | 0 | |a CELL ADHESION |
| 690 | 1 | 0 | |a CELL DIVISION |
| 690 | 1 | 0 | |a CELL LINE |
| 690 | 1 | 0 | |a ESTRADIOL |
| 690 | 1 | 0 | |a GENETIC MARKERS |
| 690 | 1 | 0 | |a HUMAN |
| 690 | 1 | 0 | |a KARYOTYPING |
| 690 | 1 | 0 | |a SUPPORT, NON-U.S. GOV'T |
| 690 | 1 | 0 | |a TAMOXIFEN |
| 690 | 1 | 0 | |a TUMOR STEM CELLS |
| 700 | 1 | |a Resnicoff, M. | |
| 700 | 1 | |a Bover, L. | |
| 700 | 1 | |a Medrano, E.E. | |
| 700 | 1 | |a Slavutsky, I. | |
| 700 | 1 | |a Larripa, I. | |
| 700 | 1 | |a Mordoh, J. | |
| 773 | 0 | |d 1988 |g v. 179 |h pp. 58-64 |k n. 1 |p Exp. Cell Res. |x 00144827 |w (AR-BaUEN)CENRE-797 |t Experimental Cell Research | |
| 856 | 4 | 1 | |u https://www.scopus.com/inward/record.uri?eid=2-s2.0-0023700205&doi=10.1016%2f0014-4827%2888%2990348-5&partnerID=40&md5=e7085e4c499aed6615e14e92c1849505 |y Registro en Scopus |
| 856 | 4 | 0 | |u https://doi.org/10.1016/0014-4827(88)90348-5 |y DOI |
| 856 | 4 | 0 | |u https://hdl.handle.net/20.500.12110/paper_00144827_v179_n1_p58_Podhajcer |y Handle |
| 856 | 4 | 0 | |u https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00144827_v179_n1_p58_Podhajcer |y Registro en la Biblioteca Digital |
| 961 | |a paper_00144827_v179_n1_p58_Podhajcer |b paper |c PE | ||
| 962 | |a info:eu-repo/semantics/article |a info:ar-repo/semantics/artículo |b info:eu-repo/semantics/publishedVersion | ||
| 999 | |c 61731 | ||