Effect of gonadotropin-releasing hormone agonist and antagonist on proliferation and apoptosis of human luteinized granulosa cells

The GnRH agonist leuprolide acetate (LA) inhibited DNA synthesis in epidermal growth factor-stimulated human granulosa luteinized cell cultures. This effect was blocked by the prior addition of a GnRH antagonist antide (ANT), and this compound per se was able to produce a stimulatory effect of DNA s...

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Autor principal: Vitale, A.M
Otros Autores: Abramovich, D., Peluffo, M.C, Meresman, G., Tesone, M.
Formato: Capítulo de libro
Lenguaje:Inglés
Publicado: 2006
Acceso en línea:Registro en Scopus
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Registro en la Biblioteca Digital
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100 1 |a Vitale, A.M. 
245 1 0 |a Effect of gonadotropin-releasing hormone agonist and antagonist on proliferation and apoptosis of human luteinized granulosa cells 
260 |c 2006 
270 1 0 |m Tesone, M.; Instituto de Biología Y Medicina Experimental, Obligado 2490, 1428 Buenos Aires, Argentina; email: mtesone@dna.uba.ar 
506 |2 openaire  |e Política editorial 
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504 |a Shapiro, D.B., An overview of GnRH antagonists in infertility treatments. Introduction (2003) Fertil Steril, 80 (1 SUPPL.), pp. 1-S7 
504 |a Andreu, C., Parborell, F., Vanzulli, S., Chemes, H., Tesone, M., Regulation of follicular luteinization by a gonadotropin-releasing hormone agonist: Relationship between steroidogenesis and apoptosis (1998) Mol Reprod Dev, 51, pp. 287-294 
504 |a Stojilkovic, S.S., Reinhart, J., Catt, K.J., Gonadotropin-releasing hormone receptors: Structure and signal transduction pathways (1994) Endocr Rev, 15, pp. 462-499 
504 |a Hsueh, A.J., Jones, P.B., Extrapituitary actions of gonadotropin-releasing hormone (1981) Endocr Rev, 2, pp. 437-461 
504 |a Behrman, H.R., Preston, S.L., Hall, A.K., Cellular mechanism of the antigonadotropic action of luteinizing hormone-releasing hormone in the corpus luteum (1980) Endocrinology, 107, pp. 656-664 
504 |a Peng, C., Fan, N., Ligier, M., Vaananen, J., Leung, P.C., Expression and regulation of gonadotropin-releasing hormone (GnRH) receptor messenger ribonucleic acids in human granulosa-luteal cells (1994) Endocrinology, 135, pp. 1740-1746 
504 |a Clayton, R.N., Harwood, J.P., Catt, K.J., Gonadotropin-releasing hormone analogue binds to luteal cells and inhibits progesterone production (1979) Nature, 282, pp. 90-92 
504 |a Sridaran, R., Philip, G.H., Li, H., Culty, M., Liu, Z., Stocco, D.M., GnRH agonist treatment decreases progesterone synthesis, luteal peripheral benzodiazepine receptor mRNA, ligand binding and steroidogenic acute regulatory protein expression during pregnancy (1999) J Mol Endocrinol, 22, pp. 45-54 
504 |a Hsueh, A.J., Adashi, E.Y., Jones, P.B., Welsh Jr., T.H., Hormonal regulation of the differentiation of cultured ovarian granulosa cells (1984) Endocr Rev, 5, pp. 76-127 
504 |a Kitajima, Y., Endo, T., Manase, K., Nishikawa, A., Shibuya, M., Kudo, R., Gonadotropin-releasing hormone agonist administration reduced vascular endothelial growth factor (VEGF), VEGF receptors, and vascular permeability of the ovaries of hyperstimulated rats (2004) Fertil Steril, 81 (1 SUPPL.), pp. 842-849 
504 |a Parborell, F., Dain, L., Tesone, M., Gonadotropin-releasing hormone agonist affects rat ovarian follicle development by interfering with FSH and growth factors on the prevention of apoptosis (2001) Mol Reprod Dev, 60, pp. 241-247 
504 |a Parborell, F., Pecci, A., Gonzalez, O., Vitale, A., Tesone, M., Effects of a gonadotropin-releasing hormone agonist on rat ovarian follicle apoptosis: Regulation by EGF and the expression of Bcl-2-related genes (2002) Biol Reprod, 67, pp. 481-486 
504 |a Irusta, G., Parborell, F., Peluffo, M., Manna, P.R., Gonzalez-Calvar, S.I., Calandra, R., Steroidogenic acute regulatory protein in ovarian follicles of gonadotropin-stimulated rats is regulated by a gonadotropin-releasing hormone agonist (2003) Biol Reprod, 68, pp. 1577-1583 
504 |a Guerrero, H.E., Stein, P., Asch, R.H., De Fried, E.P., Tesone, M., Effect of a gonadotropin-releasing hormone agonist on luteinizing hormone receptors and steroidogenesis in ovarian cells (1993) Fertil Steril, 59, pp. 803-808 
504 |a Dain, L.B., Bley, M.A., Baranao, J.L., Tesone, M., Evidence for the production of a growth-inhibitory factor by human granulosa-luteal cells (1993) Mol Reprod Dev, 36, pp. 159-163 
504 |a Tilly, J.L., Billig, H., Kowalski, K.I., Hsueh, A.J., Epidermal growth factor and basic fibroblast growth factor suppress the spontaneous onset of apoptosis in cultured rat ovarian granulosa cells and follicles by a tyrosine kinase-dependent mechanism (1992) Mol Endocrinol, 6, pp. 1942-1950 
504 |a Abrams, J.M., White, K., Fessler, L.I., Steller, H., Programmed cell death during Drosophila embryogenesis (1993) Development, 117, pp. 29-43 
504 |a Ortmann, O., Weiss, J.M., Diedrich, K., Embryo implantation and GnRH antagonists: Ovarian actions of GnRH antagonists (2001) Hum Reprod, 16, pp. 608-611 
504 |a Parborell, F., Irusta, G., Vitale, A.M., Gonzalez, O., Pecci, A., Tesone, M., GnRH antagonist antide inhibits apoptosis of preovulatory follicle cells in rat ovary (2005) Biol Reprod, 72, pp. 659-666 
504 |a Chun, S.Y., Eisenhauer, K.M., Minami, S., Billig, H., Perlas, E., Hsueh, J.W., Hormonal regulation of apoptosis in early antral follicles: Follicle-stimulating hormone as a major survival factor (1996) Endocrinology, 137, pp. 1447-1456 
504 |a Tilly, J.L., Cell death and species propagation: Molecular and genetic aspects of apoptosis in the vertebrate female gonad (1998) When Cells Die: A Comprehensive Evaluation of Apoptosis and Programmed Cell Death, pp. 431-452. , R.A. Lockshin Z. Zakeri J.L. Tilly Wiley-Liss New York 
504 |a Birnbaumer, L., Shahabi, N., Rivier, J., Vale, W., Evidence for a physiological role of gonadotropin-releasing hormone (GnRH) or GnRH-like material in the ovary (1985) Endocrinology, 116, pp. 1367-1370 
504 |a Ortmann, O., Diedrich, K., Pituitary and extrapituitary actions of gonadotrophin-releasing hormone and its analogues (1999) Hum Reprod, 14 (1 SUPPL.), pp. 194-206 
504 |a Casper, R.F., Erickson, G.F., Rebar, R.W., Yen, S.S., The effect of luteinizing hormone-releasing factor and its agonist on cultured human granulosa cells (1982) Fertil Steril, 37, pp. 406-409 
504 |a Lanzone, A., Panetta, V., Di Simone, N., Arno, E., Fulghesu, A.M., Caruso, A., Effect of gonadotrophin-releasing hormone and related analogue on human luteal cell function in vitro (1989) Hum Reprod, 4, pp. 906-909 
504 |a Minaretzis, D., Jakubowski, M., Mortola, J.F., Pavlou, S.N., Gonadotropin-releasing hormone receptor gene expression in human ovary and granulosa-lutein cells (1995) J Clin Endocrinol Metab, 80, pp. 430-434 
504 |a Lin, Y., Kahn, J.A., Hillensjo, T., Is there a difference in the function of granulosa-luteal cells in patients undergoing in-vitro fertilization either with gonadotrophin-releasing hormone agonist or gonadotrophin-releasing hormone antagonist? (1999) Hum Reprod, 14, pp. 885-888 
520 3 |a The GnRH agonist leuprolide acetate (LA) inhibited DNA synthesis in epidermal growth factor-stimulated human granulosa luteinized cell cultures. This effect was blocked by the prior addition of a GnRH antagonist antide (ANT), and this compound per se was able to produce a stimulatory effect of DNA synthesis on basal conditions. Leuprolide acetate produced an increase in the percentage of apoptotic cells, and when these two factors were co-incubated, ANT blocked the apoptotic effect produced by LA. ©2006 by American Society for Reproductive Medicine.  |l eng 
593 |a Instituto de Biología Y Medicina Experimental (IBYME), Consejo Nacional de Investigaciones Científas Y Técnicas (CONICET), Facultad de Ciencias Exactas Y Naturales, Buenos Aires, Argentina 
593 |a Instituto de Biología Y Medicina Experimental, Obligado 2490, 1428 Buenos Aires, Argentina 
690 1 0 |a ITURELIX 
690 1 0 |a LEUPRORELIN 
690 1 0 |a APOPTOSIS 
690 1 0 |a ARTICLE 
690 1 0 |a CELL PROLIFERATION 
690 1 0 |a DNA SYNTHESIS 
690 1 0 |a DRUG ANTAGONISM 
690 1 0 |a DRUG EFFECT 
690 1 0 |a GRANULOSA CELL 
690 1 0 |a HUMAN 
690 1 0 |a HUMAN CELL 
690 1 0 |a PRIORITY JOURNAL 
690 1 0 |a APOPTOSIS 
690 1 0 |a CELL PROLIFERATION 
690 1 0 |a FEMALE 
690 1 0 |a GONADOTROPIN-RELEASING HORMONE 
690 1 0 |a GRANULOSA CELLS 
690 1 0 |a HUMANS 
690 1 0 |a LEUPROLIDE 
690 1 0 |a OLIGOPEPTIDES 
700 1 |a Abramovich, D. 
700 1 |a Peluffo, M.C. 
700 1 |a Meresman, G. 
700 1 |a Tesone, M. 
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