Biosynthesis of digitoxin in Digitalis purpurea
Simultaneous administration of a mixture of [21-3H]-3β, 20ξ-dihydroxy-23-nor-5β-cholanoic acid and [21-14C]-3β-hydroxy-5β-pregnan-20-one to Digitalis purpurea intact plants produced double labelled digitoxin. The 3H: 14C ratio of the cardenolide was considerably higher than the 3H: 14C ratio of the...
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| Formato: | Capítulo de libro |
| Lenguaje: | Inglés |
| Publicado: |
1989
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| Acceso en línea: | Registro en Scopus DOI Handle Registro en la Biblioteca Digital |
| Aporte de: | Registro referencial: Solicitar el recurso aquí |
| LEADER | 03615caa a22005657a 4500 | ||
|---|---|---|---|
| 001 | PAPER-652 | ||
| 003 | AR-BaUEN | ||
| 005 | 20230518202959.0 | ||
| 008 | 190411s1989 xx ||||fo|||| 00| 0 eng|d | ||
| 024 | 7 | |2 scopus |a 2-s2.0-9844261234 | |
| 040 | |a Scopus |b spa |c AR-BaUEN |d AR-BaUEN | ||
| 030 | |a PYTCA | ||
| 100 | 1 | |a Deluca, M.E. | |
| 245 | 1 | 0 | |a Biosynthesis of digitoxin in Digitalis purpurea |
| 260 | |c 1989 | ||
| 270 | 1 | 0 | |m Deluca, M.E.; Departamento de Química Orgánica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Pabellon 2, Ciudad Universitaria, 1428 Buenos Aires, Argentina |
| 506 | |2 openaire |e Política editorial | ||
| 504 | |a Euw, Reichstein, Die Biosynthese des Digitoxigenins, Herkunft des C-20. Glykoside und Aglykone, 253. Mitteilung (1964) Helvetica Chimica Acta, 47, p. 711 | ||
| 504 | |a Tschesche, Lilienweiss, (1964) Z. Naturforsch., 19 b, p. 265 | ||
| 504 | |a Leete, Gregory, Gros, (1965) J. Am. Chem. Soc., 87, p. 3475 | ||
| 504 | |a Tschesche, Hulpke, Scholten, (1967) Z. Naturforsch., 22 b, p. 677 | ||
| 504 | |a Tschesche, Becker, Hombach, (1968) Z. Naturforsch., 23 b, p. 1615 | ||
| 504 | |a Maier, Seldes, Gros, (1986) Phytochemistry, 25, p. 1327 | ||
| 504 | |a Garraffo, Deluca, Seldes, Gros, (1985) J. Lab. Compds. Radiopharm., 22, p. 673 | ||
| 504 | |a Maier, Seldes, Gros, (1985) J. Lab. Compds. Radiopharm., 22, p. 467 | ||
| 504 | |a Deluca, Seldes, Gros, (1987) Z. Naturforsch., 42 c, p. 77 | ||
| 504 | |a Caspi, Lewis, (1967) Science, 156, p. 519 | ||
| 504 | |a Bennett, Sauer, Heftmann, (1968) Phytochemistry, 7, p. 41 | ||
| 504 | |a Caspi, Hornby, (1968) Phytochemistry, 7, p. 423 | ||
| 504 | |a Caspi, Wickramasinghe, Lewis, (1968) Biochem. J., 108, p. 499 | ||
| 520 | 3 | |a Simultaneous administration of a mixture of [21-3H]-3β, 20ξ-dihydroxy-23-nor-5β-cholanoic acid and [21-14C]-3β-hydroxy-5β-pregnan-20-one to Digitalis purpurea intact plants produced double labelled digitoxin. The 3H: 14C ratio of the cardenolide was considerably higher than the 3H: 14C ratio of the administered substrates. This result indicates that in the main biosynthetic pathway from a 20-keto-pregnane to a cardenolide the introduction of an acetate unit at C-20 should occur before the hydroxylation at C-21. © 1989. |l eng | |
| 593 | |a Departamento de Química Orgánica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Pabellon 2, Ciudad Universitaria, 1428 Buenos Aires, Argentina | ||
| 690 | 1 | 0 | |a BIOSYNTHESIS |
| 690 | 1 | 0 | |a CARDENOLIDE |
| 690 | 1 | 0 | |a DIGITALIS PURPUREA |
| 690 | 1 | 0 | |a DIGITOXIN |
| 690 | 1 | 0 | |a SCROPHULARICEAE |
| 690 | 1 | 0 | |a [21-14C]-3Β-HYDROXY-5Β-PREGNAN-20-ONE. |
| 690 | 1 | 0 | |a [21-3H]-3Β, 20Ξ-DIHYDROXY-23-NOR-5Β-CHOLANOIC ACID |
| 700 | 1 | |a Seldes, A.M. | |
| 700 | 1 | |a Gros, E.G. | |
| 773 | 0 | |d 1989 |g v. 28 |h pp. 109-111 |k n. 1 |p Phytochemistry |x 00319422 |w (AR-BaUEN)CENRE-88 |t Phytochemistry | |
| 856 | 4 | 1 | |u https://www.scopus.com/inward/record.uri?eid=2-s2.0-9844261234&doi=10.1016%2f0031-9422%2889%2985019-8&partnerID=40&md5=2d828ff32bed98c1a75e8f7c43f992e3 |y Registro en Scopus |
| 856 | 4 | 0 | |u https://doi.org/10.1016/0031-9422(89)85019-8 |y DOI |
| 856 | 4 | 0 | |u https://hdl.handle.net/20.500.12110/paper_00319422_v28_n1_p109_Deluca |y Handle |
| 856 | 4 | 0 | |u https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00319422_v28_n1_p109_Deluca |y Registro en la Biblioteca Digital |
| 961 | |a paper_00319422_v28_n1_p109_Deluca |b paper |c PE | ||
| 962 | |a info:eu-repo/semantics/article |a info:ar-repo/semantics/artículo |b info:eu-repo/semantics/publishedVersion | ||
| 963 | |a VARI | ||
| 999 | |c 61605 | ||