Eudesmanes from Pluchea sagittalis. Their antifeedant activity on Spodoptera frugiperda

Eudesmane-type sesquiterpenoids 3α-(2,3-epoxy-2-methylbutyryloxy)-4α-formoxy-11-hydroxy-6,7-dehydroeudesman-8-one (1) and 3α-(2,3-epoxy-2-methylbutyryloxy)-4α,7α,11-trihydroxyeudesman-8-one (2), together with 10 known structurally related eudesmanes were isolated from the CHCl3 extract of aerial par...

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Autor principal: Vera, N.
Otros Autores: Misico, R., Sierra, M.G, Asakawa, Y., Bardón, A.
Formato: Capítulo de libro
Lenguaje:Inglés
Publicado: 2008
Acceso en línea:Registro en Scopus
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024 7 |2 scopus  |a 2-s2.0-42749092079 
024 7 |2 cas  |a 3alpha-(2,3-epoxy-2-methylbutyryloxy)-4alpha-formoxy-11-hydroxy-6,7-dehydroeudesman-8-one; eudesmane, 473-11-0; Plant Preparations; Sesquiterpenes; Sesquiterpenes, Eudesmane 
040 |a Scopus  |b spa  |c AR-BaUEN  |d AR-BaUEN 
030 |a PYTCA 
100 1 |a Vera, N. 
245 1 0 |a Eudesmanes from Pluchea sagittalis. Their antifeedant activity on Spodoptera frugiperda 
260 |c 2008 
270 1 0 |m Bardón, A.; Instituto de Química Orgánica, Facultad de Bioquímica, Química y Farmacia, Universidad Nacional de Tucumán, Ayacucho 471, 4000 Tucumán, Argentina; email: alisan@unt.edu.ar 
506 |2 openaire  |e Política editorial 
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504 |a Ahmad, V.U., Farooqui, T.A., Fizza, K., Sultana, A., Khatoon, R., Three new eudesmane sesquiterpenes from Pluchea arguta (1992) Journal of Natural Products, 55, pp. 730-735 
504 |a Ahmad, V.U., Farooqui, T.A., Sultana, A., Fizza, K., Khatoon, R., Two sesquiterpenes from Pluchea arguta (1992) Phytochemistry, 31, pp. 2888-2890 
504 |a Ahmed, A.A., Melek, F.R., Mabry, T.J., Sulfated and non-sulfated flavonoids from Pluchea dioscoridis (1987) Journal of Natural Products, 50, p. 311 
504 |a Ahmed, A.A., El-Seedi, H.R., Mahmoud, A.A., El-Aziz, A., El-Douski, A., Zeid, I.F., Bohlin, L., Eudesmane derivatives from Laggera crispata and Pluchea carolonesis (1998) Phytochemistry, 49, pp. 2421-2424 
504 |a Anderberg, A.A., Asteraceae (1994) Cladistics & Classification, , Bremer K. (Ed), Timber Press, Portland, Oregon 
504 |a Arriaga-Giner, F.J., Borges del Castillo, M.T., Manresa-Ferrero, P., Vázquez-Bueno, F., Rodríguez, L., Valdés-Iraheta, S., Eudesmane derivatives from Pluchea odorata (1983) Phytochemistry, 22, pp. 1767-1769 
504 |a Blaney, W.M., Simmonds, M.S.J., Ley, S.V., Anderson, J.C., Toogood, P.L., Antifeedant effects of azadirachtin and structurally related compounds on lepidopterous larvae (1990) Entomologia Experimentalis et Applicata, 55, pp. 149-160 
504 |a Bohlmann, F., Mahanta, P.K., Neue eudesman-derivate aus Pluchea foetida (1978) Phytochemistry, 17, pp. 1189-1190 
504 |a Bolhmann, F., Ziesche, J., King, R.M., Robinson, H., Neue eudesman-derivate aus Pluchea suaveolens (1980) Phytochemistry, 19, pp. 969-970 
504 |a Bohlmann, F., Wallmeyer, M., Jakupovic, J., Gerke, T., King, R.M., Robinson, H., Cuauthemone sesquiterpenoids from Blumea alata (1985) Phytochemistry, 24, pp. 505-509 
504 |a Burket, U., Allinger, N.L., 1982. Molecular Mechanics, ACS Monograph, vol. 177. American Chemical Society, Washington, DC; Chiang, M.T., Bittner, M., Silva, M., Watson, W.H., Sammes, P.G., A new sesquiterpene from Pluchea chingoyo (1979) Phytochemistry, 18, p. 2033 
504 |a Chakravarty, A.K., Mukhopadhyay, S., New thiophene derivatives from Pluchea indica (1994) Indian Journal of Chemistry, 33 B, pp. 978-980 
504 |a Dominguez, X.A., Franco, R., Cano, G., Villarreal, R.B., Maringanti, B., Bolhmann, F., Three eudesmanolides from Pluchea rosea (1981) Phytochemistry, 20, pp. 2297-2298 
504 |a Faini, F., Labbe, C., Torres, R., Delle Monache, G., Delle Monache, F., Coll, J., Eudesmane derivatives from Flourensia thurifera: structure and biological activity (1997) Natural Products Letters, 11, pp. 1-4 
504 |a Guilhon, G.M.S.P., Müller, A.H., Eudesmane derivatives from Pluchea quitoc (1996) Phytochemistry, 43, pp. 417-421 
504 |a Guilhon, G.M.S.P., Müller, A.H., Eudesmane sesquiterpenoids from Pluchea quitoc (1998) Phytochemistry, 47, pp. 227-229 
504 |a Guilhon, G.M.S.P., Müller, A.H., Eudesmanolides and epoxycuauthemones from Pluchea quitoc (1998) Phytochemistry, 49, pp. 1347-1351 
504 |a Mahmoud, A., 7-Epi-eudesmanes, eudesmanoic acids, eudesmanolides and other sesquiterpenes from Pluchea dioscoridis (1997) Phytochemistry, 45, pp. 1633-1688 
504 |a Mukhopadhyay, S., Cordell, G.A., Ruangrungsi, N., Rodkird, S., Tantivatana, P., Hylands, P.J., 3-(2,3-diacetoxy-2-methylbutyryl)-cauthemone from Pluchea indica (1983) Journal of Natural Products, 46, pp. 671-674 
504 |a Perez-García, F., Marín, E., Cañigueral, S., Adzet, T., Anti-inflammatory action of Pluchea sagittalis: involvement of an antioxidant mechanism (1996) Life Sciences, 59, pp. 2033-2040 
504 |a Perez-García, F., Marín, E., Parella, T., Adzet, T., Cañigueral, S., Activity of taraxasteryl acetate on inflammation and heat shock protein synthesis (2005) Phytomedicine, 12, pp. 278-284 
504 |a Scholz, E., Heinrich, M., Hunkler, D., Caffeoylquinic acids and some biological activities of Pluchea symphytifolia (1994) Planta Medica, 60, pp. 360-364 
504 |a Soraru, S.B., Bandoni, A.L., (1979) Plantas de la Medicina Popular Argentina, , Ed. Albatros, Buenos Aires 
504 |a Srivastava, R.P., Proksch, P., Wray, V., Toxicity and antifeedant activity of a sesquiterpene lactone from Encelia against Spodoptera littoralis (1990) Phytochemistry, 29, pp. 3445-3448 
504 |a Uchiyama, T., Miyase, T., Ueno, A., Usmanghani, K., Terpene and lignan glycosides from Pluchea indica (1991) Phytochemistry, 30, pp. 655-657 
504 |a note 
520 3 |a Eudesmane-type sesquiterpenoids 3α-(2,3-epoxy-2-methylbutyryloxy)-4α-formoxy-11-hydroxy-6,7-dehydroeudesman-8-one (1) and 3α-(2,3-epoxy-2-methylbutyryloxy)-4α,7α,11-trihydroxyeudesman-8-one (2), together with 10 known structurally related eudesmanes were isolated from the CHCl3 extract of aerial parts of Pluchea sagittalis (Lamarck) Cabrera. Their structures were deduced by extensive application of 1 and 2D NMR spectroscopic techniques and high and low resolution CIMS. X-ray crystallographic analysis of the known compound 3α-(2,3-epoxy-2-methylbutyryloxy)-4α-formoxycuauthemone (9) is reported here for the first time, and confirms the structural features for the series of the reported eudesmanes. All eudesmanes were tested for their antifeedant activity by incorporating them to an artificial diet of larvae of the polyphagous insect Spodoptera frugiperda at a concentration of 100 ppm. Our results, from feeding choice tests, indicated that most of the compounds deter larval feeding at the cited concentration. © 2008 Elsevier Ltd. All rights reserved.  |l eng 
536 |a Detalles de la financiación: Consejo Nacional de Investigaciones Científicas y Técnicas 
536 |a Detalles de la financiación: Agencia Nacional de Promoción Científica y Tecnológica 
536 |a Detalles de la financiación: Universidad Nacional de Tucumán 
536 |a Detalles de la financiación: Authors thank Ms. Y. Okamoto (TBU, Japan) for recording mass sprectra, Dr. M. Tanaka (TBU) for 600 MHz NMR, and Mr. S. Takaoka (TBU) for X-ray crystallographic analysis. Work in Argentina was supported by grants from Agencia Nacional de Promoción Científica y Tecnológica (ANPCyT), Consejo Nacional de Investigaciones Científicas y Técnicas de Argentina (CONICET) and Consejo de Investigaciones de la Universidad Nacional de Tucumán (CIUNT). Appendix A 
593 |a Instituto de Química Orgánica, Facultad de Bioquímica, Química y Farmacia, Universidad Nacional de Tucumán, Ayacucho 471, 4000 Tucumán, Argentina 
593 |a Departamento de Química Orgánica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Pabellón 2, Ciudad Universitaria AR-, 1428, Argentina 
593 |a Instituto de Química Orgánica y Síntesis (IQUIOS), Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Suipacha 531, 2000 Rosario, Argentina 
593 |a Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-cho, Tokushima, 770-8514, Japan 
690 1 0 |a ANTIFEEDANT ACTIVITY 
690 1 0 |a ASTERACEAE 
690 1 0 |a EUDESMANES 
690 1 0 |a PLUCHEA SAGITTALIS 
690 1 0 |a SESQUITERPENOIDS 
690 1 0 |a SPODOPTERA FRUGIPERDA 
690 1 0 |a 3ALPHA (2,3 EPOXY 2 METHYLBUTYRYLOXY) 4ALPHA FORMOXY 11 HYDROXY 6,7 DEHYDROEUDESMAN 8 ONE 
690 1 0 |a 3ALPHA-(2,3-EPOXY-2-METHYLBUTYRYLOXY)-4ALPHA-FORMOXY-11-HYDROXY-6,7-DEHYDROEUDESMAN-8-ONE 
690 1 0 |a EUDESMANE 
690 1 0 |a PLANT MEDICINAL PRODUCT 
690 1 0 |a SESQUITERPENE 
690 1 0 |a ANIMAL 
690 1 0 |a ARMYWORM 
690 1 0 |a ARTICLE 
690 1 0 |a ASTERACEAE 
690 1 0 |a CHEMICAL STRUCTURE 
690 1 0 |a CHEMISTRY 
690 1 0 |a DRUG EFFECT 
690 1 0 |a FEEDING BEHAVIOR 
690 1 0 |a LARVA 
690 1 0 |a PLANT 
690 1 0 |a SYNTHESIS 
690 1 0 |a X RAY CRYSTALLOGRAPHY 
690 1 0 |a ANIMALS 
690 1 0 |a ASTERACEAE 
690 1 0 |a CRYSTALLOGRAPHY, X-RAY 
690 1 0 |a FEEDING BEHAVIOR 
690 1 0 |a LARVA 
690 1 0 |a MOLECULAR STRUCTURE 
690 1 0 |a PLANT COMPONENTS, AERIAL 
690 1 0 |a PLANT PREPARATIONS 
690 1 0 |a SESQUITERPENES 
690 1 0 |a SESQUITERPENES, EUDESMANE 
690 1 0 |a SPODOPTERA 
690 1 0 |a ASTERACEAE 
690 1 0 |a CABRERA 
690 1 0 |a HEXAPODA 
690 1 0 |a LEPIDOPTERA 
690 1 0 |a PLUCHEA SAGITTALIS 
690 1 0 |a SPODOPTERA FRUGIPERDA 
700 1 |a Misico, R. 
700 1 |a Sierra, M.G. 
700 1 |a Asakawa, Y. 
700 1 |a Bardón, A. 
773 0 |d 2008  |g v. 69  |h pp. 1689-1694  |k n. 8  |p Phytochemistry  |x 00319422  |w (AR-BaUEN)CENRE-88  |t Phytochemistry 
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