Association between mast cells of different phenotypes and angiogenesis in colorectal cancer
It is known that mast cells proliferate in solid tumours and increase tumour angiogenesis. Nevertheless, there is no consensus regarding their role in colorectal cancer (CRC). In this study, we aimed to clarify the relationship of mast cells positive for tryptase (MCts) and tryptase-chymase (MCtcs)...
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| Otros Autores: | , , , , , , , , |
| Formato: | Capítulo de libro |
| Lenguaje: | Inglés |
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2008
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| Acceso en línea: | Registro en Scopus DOI Handle Registro en la Biblioteca Digital |
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| LEADER | 13176caa a22012137a 4500 | ||
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| 001 | PAPER-5522 | ||
| 003 | AR-BaUEN | ||
| 005 | 20230518203510.0 | ||
| 008 | 190411s2008 xx ||||fo|||| 00| 0 eng|d | ||
| 024 | 7 | |2 scopus |a 2-s2.0-69249098531 | |
| 024 | 7 | |2 cas |a chymase, 75496-62-7, 97501-92-3; tryptase, 97501-93-4 | |
| 040 | |a Scopus |b spa |c AR-BaUEN |d AR-BaUEN | ||
| 100 | 1 | |a Mauro, L.V. | |
| 245 | 1 | 0 | |a Association between mast cells of different phenotypes and angiogenesis in colorectal cancer |
| 260 | |c 2008 | ||
| 270 | 1 | 0 | |m De Cidre, L. L.; Facultad de Ciencias Exactas Y Naturales, Departamento de Biodiversidad Y Biología Experimental, Ciudad Universitaria, C1428EHA Buenos Aires, Argentina; email: laurial@bg.fcen.uba.ar |
| 506 | |2 openaire |e Política editorial | ||
| 504 | |a Naukarinen, A., Syrijänen, K., Quantitative immunohistochemical analysis of mononuclear infiltrates in breast carcinomas. Correlation with tumour differentiation (1990) J Pathol, 160, pp. 217-222 | ||
| 504 | |a Lauria De Cidre, L., Sacerdote De Lustig, E., Mast cell kinetics during tumor growth (1990) Tumor Biology, 11 (4), pp. 196-201 | ||
| 504 | |a Conti, P., Castellani, M.L., Kempuraj, D., Salini, V., Vecchiet, J., Tete, S., Mastrangelo, F., Theoharides, T.C., Review: Role of mast cells in tumor growth (2007) Annals of Clinical and Laboratory Science, 37 (4), pp. 315-322 | ||
| 504 | |a Shiohara, M., Koike, K., Regulation of mast cell development (2005) Chem Immunol Allergy, 87, pp. 1-21 | ||
| 504 | |a Norrby, K., Mast cells and angiogenesis (2002) APMIS, 110, pp. 355-371 | ||
| 504 | |a Irani, A.M., Schwartz, L.B., Human mast cell heterogeneity (1994) Allergy Proc, 15, pp. 303-308 | ||
| 504 | |a Norrby, K., Wooly, D., Role of mast cells in mitogenesis and angiogenesis in normal tissue and tumour tissue (1993) Adv Biosci, 89, pp. 71-116 | ||
| 504 | |a Yano, H., Kinuta, M., Tateishi, H., Nakano, Y., Matsui, S., Monden, T., Okamura, J., Okamoto, S., Mast cell infiltration around gastric cancer cells correlates with tumour angiogenesis and metastasis (1999) Gastric Cancer, 2, pp. 26-32 | ||
| 504 | |a Elpek, G.O., Gelen, T., Aksoy, N.H., Erdogan, A., Dertsiz, L., Demircan, A., Keles, N., The prognostic relevance of angiogenesis and mast cells in squamous cell carcinoma of the oesophagus (2001) Journal of Clinical Pathology, 54 (12), pp. 940-944 | ||
| 504 | |a Ghiara, P., Boraschi, D., Villa, L., Scapigliati, G., Taddei, C., Tagliabue, A., In vitro generated mast cells express natural cytotoxicity against tumor cells (1985) Immunology, 55, pp. 317-324 | ||
| 504 | |a Aaltomaa, S., Lipponen, P., Papinaho, S., Kosma, V.M., Mast cells in breast cancer (1993) Anticancer Res, 13, pp. 785-788 | ||
| 504 | |a Bertolesi, G.E., De Lauría Cidre, L., Eijan, A., Growth inhibition in vitro of murine mammary adenocarcinoma cells by heparin and chemically modified heparins (1994) Tumor Biol, 15, pp. 275-283 | ||
| 504 | |a Bertolesi, G.E., De Lauría Cidre, L., De Sacerdote Lustig, E., Eiján, A., Heparin receptors in two murine mammary adenocarcinomas with different metastatic ability (1995) Cancer Lett, 90, pp. 123-131 | ||
| 504 | |a De Cidre, L.L., Eijan, A.M., Bertolesi, G., Isturiz, M., De Lustig, E.S., Influence of mast cells on two murine mammary adenocarcinomas (1996) Tumor Biology, 17 (6), pp. 345-353 | ||
| 504 | |a Tomita, M., Matsuzaki, Y., Onitsuka, T., Correlation between mast cells and survival rates in patients with pulmonary adenocarcinoma (1999) Lung Cancer, 26 (2), pp. 103-108. , DOI 10.1016/S0169-5002(99)00076-8, PII S0169500299000768 | ||
| 504 | |a Tan, S.-Y., Fan, Y., Luo, H.-S., Shen, Z.-X., Guo, Y., Zhao, L.-J., Prognostic significance of cell infiltrations of immunosurveillance in colorectal cancer (2005) World Journal of Gastroenterology, 11 (8), pp. 1210-1214 | ||
| 504 | |a Syrjanen, K.J., Hjelt, L.H., Host-host relationships in colorectal carcinoma (1978) Dis Colon Rectum, 21, pp. 29-36 | ||
| 504 | |a Fisher, E.R., Paik, S.M., Rockette, H., Jones, J., Caplan, R., Fisher, B., Prognostic significance of eosinophils and mast cells in rectal cancer: Findings from the National Surgical Adjuvant Breast and Bowel Project (protocol R-01) (1989) Human Pathology, 20 (2), pp. 159-163. , DOI 10.1016/0046-8177(89)90180-9 | ||
| 504 | |a Acikalin, M.F., Oner, U., Topcu, I., Yasar, B., Kiper, H., Colak, E., Tumour angiogenesis and mast cell density in the prognostic assessment of colorectal carcinomas (2005) Digestive and Liver Disease, 37 (3), pp. 162-169. , DOI 10.1016/j.dld.2004.09.028, PII S1590865804004852 | ||
| 504 | |a Friend, D.S., Ghildyal, N., Gurish, M.F., Hunt, J., Hu, X., Austen, K.F., Stevens, R.L., Reversible expression of tryptases and chymases in the jejunal mast cells of mice infected with Trichinella spiralis (1998) Journal of Immunology, 160 (11), pp. 5537-5545 | ||
| 504 | |a Gruber, B.L., Mast cells in the pathogenesis of fibrosis (2003) Curr Rheumatol Rep, 5, pp. 147-153 | ||
| 504 | |a Wang, H.-W., Tedla, N., Hunt, J.E., Wakefield, D., McNeil, H.P., Mast cell accumulation and cytokine expression in the tight skin mouse model of scleroderma (2005) Experimental Dermatology, 14 (4), pp. 295-302. , DOI 10.1111/j.0906-6705.2005.00315.x | ||
| 504 | |a Tchougounova, E., Lundequist, A., Fajardo, I., Winberg, J.-O., Abrink, M., Pejler, G., A key role for mast cell chymase in the activation of pro-matrix metalloprotease-9 and pro-matrix metalloprotease-2 (2005) Journal of Biological Chemistry, 280 (10), pp. 9291-9296. , DOI 10.1074/jbc.M410396200 | ||
| 504 | |a Paine, V., Kam, P.C.A., Mast cell tryptase: A review of its physiology and clinical significance (2004) Anesthesia, 59, pp. 695-703 | ||
| 504 | |a Urata, H., Boehm, K.D., Philip, A., Kinoshita, A., Gabrovsek, J., Bumpus, F.M., Husain, A., Cellular localization and regional distribution of an angiotensin II- Forming chymase in the heart (1993) Journal of Clinical Investigation, 91 (4), pp. 1269-1281 | ||
| 504 | |a Dvorak, A.M., Ultrastructural studies of human basophils and mast cells (2005) Journal of Histochemistry and Cytochemistry, 53 (9), pp. 1043-1070. , DOI 10.1369/jhc.5R6647.2005 | ||
| 504 | |a Kankkunen, J.P., Harvima, I.T., Naukkarinen, A., Quantitative analysis of tryptase and chymase containing mast cells in benign and malignant breast lesions (1997) Int J Cancer, 72, pp. 385-388 | ||
| 504 | |a Beil, W.J., Fureder, W., Wiener, H., Grossschmidt, K., Maier, U., Schedle, A., Bankl, H.C., Valent, P., Phenotypic and functional characterization of mast cells derived from renal tumor tissues (1998) Experimental Hematology, 26 (2), pp. 158-169 | ||
| 504 | |a Ribatti, D., Vacca, A., Marzullo, A., Nico, B., Ria, R., Roncali, L., Dammacco, F., Angiogenesis and mast cell density with tryptase activity increase simultaneously with pathological progression in B-cell non-Hodgkin's lymphomas (2000) International Journal of Cancer, 85 (2), pp. 171-175. , DOI 10.1002/(SICI)1097-0215(20000115)85:2<171::AID-IJC4>3.0.CO;2-W | ||
| 504 | |a Cabanillas-Saez, A., Schalper, J.A., Nicovani, S.M., Rudolph, M.I., Characterization of mast cells according to their content of tryptase and chymase in normal and neoplastic human uterine cervix (2002) International Journal of Gynecological Cancer, 12 (1), pp. 92-98. , DOI 10.1046/j.1525-1438.2002.01082.x | ||
| 504 | |a Folkman, J., What is the evidence that tumours are angiogenesis dependent? (1990) J Natl Cancer Inst, 82, pp. 4-6 | ||
| 504 | |a De Castro Junior, G., Puglisi, F., De Azambuja, E., El Saghir, N.S., Awada, A., Angiogenesis and cancer: A cross-talk between basic science and clinical trials (the 'do ut des' paradigm) (2006) Critical Reviews in Oncology/Hematology, 59 (1), pp. 40-50. , DOI 10.1016/j.critrevonc.2006.02.007, PII S1040842806000436 | ||
| 504 | |a Sawatsubashi, M., Yamada, T., Fukushima, N., Mizokami, H., Tokunaga, O., Shin, T., Association of vascular endothelial growth factor and mast cells with angiogenesis in laryngeal squamous cell carcinoma (2000) Virchows Archiv, 436 (3), pp. 243-248 | ||
| 504 | |a Ch'Ng, S., Wallis, R.A., Yuan, L., Davis, P.F., Tan, S.T., Mast cells and cutaneous malignancies (2006) Mod Pathol, 19, pp. 149-159 | ||
| 504 | |a Vermeulen, P.B., Verhoeven, D., Fierens, H., Hubens, G., Goovaerts, G., Van Marck, E., De Bruijn, E.A., Dirix, L.Y., Microvessel quantification in primary colorectal carcinoma: An immunohistochemical study (1995) Br J Cancer, 71, pp. 340-343 | ||
| 504 | |a Lindmark, G., Gerdin, B., Sundberg, C., Pahlman, L., Bergstrom, R., Glimelius, B., Prognostic significance of the microvascular count in colorectal cancer (1996) Journal of Clinical Oncology, 14 (2), pp. 461-466 | ||
| 504 | |a Pretlow, T.P., Keith, E.F., Cryar, A.K., Bartolucci, A.A., Pitts, A.M., Pretlow, T.G., Kimball, P.M., Boohaker, E.A., Eosinophil infiltration of human colonic carcinomas as a prognostic indicator (1983) Cancer Res, 43, pp. 2997-3000 | ||
| 504 | |a McShane, L., Altman, D., Sauerbrei, W., Statistics Subcommittee of the NCI-EORTC Working Group on Cancer Diagnostics. 1180 Commentary (2005) J Natl Cancer Inst, 97, pp. 1180-1184 | ||
| 520 | 3 | |a It is known that mast cells proliferate in solid tumours and increase tumour angiogenesis. Nevertheless, there is no consensus regarding their role in colorectal cancer (CRC). In this study, we aimed to clarify the relationship of mast cells positive for tryptase (MCts) and tryptase-chymase (MCtcs) with microvessel density (MVD) in the intratumoral zone and the invasive edge of 80 CRC patient tumours. We evaluated these parameters and associated their expression with clinicopathological parameters, including survival rate. Tumour sections from each patient were immunostained for tryptase to evaluate MCts, chymase to evaluate MCtcs, and CD34 to evaluate microvessel counts under x100 microscopy. The number of MCs of both phenotypes and the MVD counts were higher in the invasive edge than in the intratumoral zone (p<0.001). MCt numbers were higher than those of MCtcs in all Astler-Coller stages in both regions. A positive correlation between MVD and MCts or MCtcs was observed (Pearson's test p<0.001). Neither the number of MCs nor MVD was associated with overall survival (log rank test). However, only 8.3% of patients with low numbers of MCtcs in the invasive edge succumbed to the disease, compared to 32% with high numbers of MCtcs. Our results indicate that angiogenesis and MC hyperplasia are events which appear early during CRC development. The correlation of MC phenotypes with MVD is in agreement with the role attributed to MCs, that of angiogenesis enhancement. Collectively, these findings suggest that screening during the early malignization of CRC can provide valuable clinical information. |l eng | |
| 593 | |a Area Investigación del Instituto de Oncología 'Ángel H. Roffo', Av. San Martín 5481, C1417DTB Buenos Aires, Argentina | ||
| 593 | |a Facultad de Ciencias Exactas Y Naturales, Departamento de Biodiversidad Y Biología Experimental, Ciudad Universitaria, C1428EHA Buenos Aires, Argentina | ||
| 593 | |a Departamentos de Clínica Oncológica, Patología Y Gastroenterología, Hospital Italiano, Gascón 450, C1181ACH Buenos Aires, Argentina | ||
| 593 | |a National Council of Scientific and Technical Research (CONICET), Argentina | ||
| 690 | 1 | 0 | |a ANGIOGENESIS |
| 690 | 1 | 0 | |a COLORECTAL CARCINOMA |
| 690 | 1 | 0 | |a IMMUNOHISTOCHEMISTRY |
| 690 | 1 | 0 | |a MAST CELL CHYMASE |
| 690 | 1 | 0 | |a MAST CELL TRYPTASE |
| 690 | 1 | 0 | |a CHYMASE |
| 690 | 1 | 0 | |a TRYPTASE |
| 690 | 1 | 0 | |a ANGIOGENESIS |
| 690 | 1 | 0 | |a ARTICLE |
| 690 | 1 | 0 | |a CANCER STAGING |
| 690 | 1 | 0 | |a CANCER SURVIVAL |
| 690 | 1 | 0 | |a CELL PROLIFERATION |
| 690 | 1 | 0 | |a COLORECTAL CANCER |
| 690 | 1 | 0 | |a CONTROLLED STUDY |
| 690 | 1 | 0 | |a CORRELATION ANALYSIS |
| 690 | 1 | 0 | |a DISEASE ASSOCIATION |
| 690 | 1 | 0 | |a ENZYME ACTIVITY |
| 690 | 1 | 0 | |a HUMAN |
| 690 | 1 | 0 | |a HUMAN CELL |
| 690 | 1 | 0 | |a HUMAN TISSUE |
| 690 | 1 | 0 | |a IMMUNOHISTOCHEMISTRY |
| 690 | 1 | 0 | |a MAST CELL |
| 690 | 1 | 0 | |a MICROSCOPY |
| 690 | 1 | 0 | |a OVERALL SURVIVAL |
| 690 | 1 | 0 | |a PHENOTYPE |
| 690 | 1 | 0 | |a RETROSPECTIVE STUDY |
| 690 | 1 | 0 | |a SURVIVAL RATE |
| 700 | 1 | |a Bellido, M. | |
| 700 | 1 | |a Morandi, A. | |
| 700 | 1 | |a Bonadeo, F. | |
| 700 | 1 | |a Vaccaro, C. | |
| 700 | 1 | |a Quintana, G.O. | |
| 700 | 1 | |a Pallotta, M.G. | |
| 700 | 1 | |a Lastiri, J. | |
| 700 | 1 | |a Puricelli, L.I. | |
| 700 | 1 | |a De Cidre, L.L. | |
| 773 | 0 | |d 2008 |g v. 1 |h pp. 895-902 |k n. 6 |p Mol. Med. Rep. |x 17912997 |t Molecular Medicine Reports | |
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