Tamm-Horsfall protein excretion to predict the onset of renal insufficiency
Objective: Immunosuppressive therapy after liver transplantation may be a risk for kidney dysfunction. This work was designed to determine whether Tamm-Horsfall Protein (THP) could be considered as a marker for nephrotoxicity. Design and Methods: THP was determined by an ELISA method in serial 24-h...
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| Otros Autores: | , , , , |
| Formato: | Capítulo de libro |
| Lenguaje: | Inglés |
| Publicado: |
2002
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| Acceso en línea: | Registro en Scopus DOI Handle Registro en la Biblioteca Digital |
| Aporte de: | Registro referencial: Solicitar el recurso aquí |
| LEADER | 08142caa a22011177a 4500 | ||
|---|---|---|---|
| 001 | PAPER-5375 | ||
| 003 | AR-BaUEN | ||
| 005 | 20230518203501.0 | ||
| 008 | 190411s2002 xx ||||fo|||| 00| 0 eng|d | ||
| 024 | 7 | |2 scopus |a 2-s2.0-0036214618 | |
| 024 | 7 | |2 cas |a Biological Markers; Creatinine, 60-27-5; Mucoproteins; Tamm-Horsfall protein | |
| 040 | |a Scopus |b spa |c AR-BaUEN |d AR-BaUEN | ||
| 030 | |a CLBIA | ||
| 100 | 1 | |a Romero, M.C. | |
| 245 | 1 | 0 | |a Tamm-Horsfall protein excretion to predict the onset of renal insufficiency |
| 260 | |c 2002 | ||
| 270 | 1 | 0 | |m Romero, M.C.; Departmento de Quimica Biologica, Fac. de Ciencias Exactas y Naturales, Universidad de Buenos Aires, (1428) Cd. Autonoma de Buenos Aires, Argentina; email: cris@qb.fcen.uba.ar |
| 506 | |2 openaire |e Política editorial | ||
| 504 | |a Hoyer, J.R., Seiler, M.W., Pathophysiology of Tamm-Horsfall protein (1979) Kidney Int, 16, pp. 279-289 | ||
| 504 | |a Sikri, K.L., Foster, C.L., Bloomfield, F.J., Marshall, R.D., Localization by immunofluorescence and by light- and electro-microscopic immunoperoxidase of Tamm-Horsfall glycoprotein in adult hamster kidney (1979) Biochem J, 181, pp. 525-532 | ||
| 504 | |a Kokot, F., Dulawa, J., Tamm-Horsfall protein updated (2000) Nephron, 85, pp. 97-102 | ||
| 504 | |a Lynn, K.L., Marshall, R.D., Excretion of Tamm-Horsfall glycoprotein in renal disease (1984) Clin Nephrol, 22, pp. 253-257 | ||
| 504 | |a Dehne, M.G., Sablotzki, A., Muhling, J., Papke, G., Kuntzsch, U., Hempelmann, G., Acute kidney failure. Non-invasive diagnosis of acute kidney failure in operative intense care patients (1998) Anaesthesist, 47, pp. 193-201 | ||
| 504 | |a Zimmerhackl, L.B., Evaluation of nephrotoxicity with renal antigens in children: Role of Tamm-Horsfall protein (1993) Eur J Clin Pharmacol, 44 (SUPPL. 1), pp. S39-S42 | ||
| 504 | |a Torffvit, O., Jørgensen, P.E., Kamper, A.L., Urinary excretion of Tamm-Horsfall protein and epidermal growth factor in chronic nephropathy (1998) Nephron, 79, pp. 167-172 | ||
| 504 | |a Kaden, J., Groth, J., May, G., Liedvogel, B., Urinary Tamm-Horsfall protein as a marker of renal transplant function (1994) Urol Res, 22, pp. 131-136 | ||
| 504 | |a Torffvit, O., Agardh, C.-D., Tubular secretion of Tamm-Horsfall Protein is decreased in type 1 (Insulin-Dependent) diabetic patients with diabetic Nephropathy (1993) Nephron, 65, pp. 227-231 | ||
| 504 | |a Torffvit, O., Agardh, C.-D., Thulin, T., A study of Tamm-Horsfall protein excretion in hyperthensive patients, and type 1 diabetic patients (1999) Scand J Urol Nephrol, 33, pp. 187-191 | ||
| 504 | |a Dehne, M.G., Boldt, J., Heise, D., Sablotzki, A., Hempelmann, G., Tamm-Horsfall protein, alpha-1, and beta-2 microglobulin as kidney function markers in heart surgery (1995) Anaesthesist, 44, pp. 545-551 | ||
| 504 | |a Burns, A.M., Hue, D.P., Wraight, E.P., Park, G.R., Creatinine and 51Cr-EDTA clearance after liver transplantation (1993) Anaesthesia, 48, pp. 763-765 | ||
| 504 | |a De Santo, N.G., Anastasio, P., Loguercio, C., Creatinine clearance: An inadequate marker of renal filtration in patients with early posthepatitic cirrhosis (Child A) without fluid retention and muscle wasting (1995) Nephron, 70, pp. 421-424 | ||
| 504 | |a Woitas, R.P., Stoffel-Wagner, B., Flommersfeld, S., Correlation of serum concentrations of Cystatin C and Creatinine to Inulin Clearance in Liver Cirrhosis (2000) Clin Chem, 46, pp. 712-715 | ||
| 504 | |a Romero, M.C., Nocera, S., Nesse, A., Decreased Tamm-Horsfall protein in lithiasic patients (1997) Clin Biochem, 30, pp. 63-67 | ||
| 504 | |a Richet, G., The mechanism of action of some loop-acting diuretics: Role of binding to Tamm-Horsfall protein (1983) Clin Nephrol, 19 (SUPPL.), pp. 42-44 | ||
| 520 | 3 | |a Objective: Immunosuppressive therapy after liver transplantation may be a risk for kidney dysfunction. This work was designed to determine whether Tamm-Horsfall Protein (THP) could be considered as a marker for nephrotoxicity. Design and Methods: THP was determined by an ELISA method in serial 24-h urine from liver transplant patients. Fourteen patients suffered renal insufficiency (LTr1) and 20 showed no acute renal damage (LTr2) after liver transplantation. Results: No clear association could be seen between daily THP excretion and plasma creatinine levels by comparing serial samples collected at the same time. Nevertheless, significant differences were observed in pretransplant THP excretion between both groups of patients. The results (Median/Interquartile Range) were: Controls: 113.2/84.9 to 146.8 mg/24 h (n = 30); LTr1: 36.9/18.3 to 54.5 mg/24 h (p≪0.001 with respect to C and LTr2); LTr2: 90.8/61.5 to 139.7 mg/24 h. Conclusions: The higher pretransplant synthesis and/or secretion of THP seem to have a protective role on the kidney during and after liver transplantation. © 2002 The Canadian Society of Clinical Chemists. All rights reserved. |l eng | |
| 536 | |a Detalles de la financiación: Universidad de Buenos Aires | ||
| 536 | |a Detalles de la financiación: Consejo Nacional de Investigaciones Científicas y Técnicas | ||
| 536 | |a Detalles de la financiación: Consejo Nacional de Investigaciones Científicas y Técnicas | ||
| 536 | |a Detalles de la financiación: The authors are grateful to Dr. Carla Lavagno for her advice on the English translation. Results of this work were partially presented at the XVth. International Congress of Nephrology, Buenos Aires, Argentina, May 1999. This research was supported by grants from the Consejo Nacional de Investigaciones Cientı́ficas y Técnicas (CONICET, Argentina) and the Universidad de Buenos Aires, Argentina. | ||
| 593 | |a Departmento de Química Biológica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, 1428 Cd. Auton. Buenos Aires, Argentina | ||
| 593 | |a Hospital General de Agudos Dr. Cosme Argerich, Gobierno de la Ciudad Autónoma de Buenos Aires, Argentina | ||
| 690 | 1 | 0 | |a BIOCHEMICAL MARKERS |
| 690 | 1 | 0 | |a IMMUNOTHERAPY |
| 690 | 1 | 0 | |a LIVER TRANSPLANTATION |
| 690 | 1 | 0 | |a NEPHROTOXICITY |
| 690 | 1 | 0 | |a RENAL INSUFFICIENCY |
| 690 | 1 | 0 | |a TAMM-HORSFALL PROTEIN |
| 690 | 1 | 0 | |a CREATININE |
| 690 | 1 | 0 | |a TAMM HORSFALL GLYCOPROTEIN |
| 690 | 1 | 0 | |a ADULT |
| 690 | 1 | 0 | |a AGED |
| 690 | 1 | 0 | |a ARTICLE |
| 690 | 1 | 0 | |a CLINICAL ARTICLE |
| 690 | 1 | 0 | |a CONTROLLED STUDY |
| 690 | 1 | 0 | |a CREATININE BLOOD LEVEL |
| 690 | 1 | 0 | |a DISEASE MARKER |
| 690 | 1 | 0 | |a ENZYME LINKED IMMUNOSORBENT ASSAY |
| 690 | 1 | 0 | |a FEMALE |
| 690 | 1 | 0 | |a HUMAN |
| 690 | 1 | 0 | |a KIDNEY FAILURE |
| 690 | 1 | 0 | |a LIVER TRANSPLANTATION |
| 690 | 1 | 0 | |a MALE |
| 690 | 1 | 0 | |a PREDICTION |
| 690 | 1 | 0 | |a PRIORITY JOURNAL |
| 690 | 1 | 0 | |a PROTEIN SECRETION |
| 690 | 1 | 0 | |a PROTEIN SYNTHESIS |
| 690 | 1 | 0 | |a URINALYSIS |
| 690 | 1 | 0 | |a URINARY EXCRETION |
| 690 | 1 | 0 | |a ADOLESCENT |
| 690 | 1 | 0 | |a ADULT |
| 690 | 1 | 0 | |a AGED |
| 690 | 1 | 0 | |a BIOLOGICAL MARKERS |
| 690 | 1 | 0 | |a CREATININE |
| 690 | 1 | 0 | |a FEMALE |
| 690 | 1 | 0 | |a HUMANS |
| 690 | 1 | 0 | |a IMMUNOASSAY |
| 690 | 1 | 0 | |a KIDNEY |
| 690 | 1 | 0 | |a KIDNEY FAILURE |
| 690 | 1 | 0 | |a KIDNEY TRANSPLANTATION |
| 690 | 1 | 0 | |a MALE |
| 690 | 1 | 0 | |a MIDDLE AGED |
| 690 | 1 | 0 | |a MUCOPROTEINS |
| 690 | 1 | 0 | |a TIME FACTORS |
| 700 | 1 | |a Zanaro, N. | |
| 700 | 1 | |a González, L. | |
| 700 | 1 | |a Trigo, P. | |
| 700 | 1 | |a Imventarza, O. | |
| 700 | 1 | |a Nesse, A. | |
| 773 | 0 | |d 2002 |g v. 35 |h pp. 65-68 |k n. 1 |p Clin. Biochem. |x 00099120 |w (AR-BaUEN)CENRE-4213 |t Clinical Biochemistry | |
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