Differentiating effect of l-tyrosine on the human melanoma cell line IIB-MEL-J
IIB-MEL-J is a highly heterogeneous newly established human melanoma cell line. The addition of 3 mM, l-tyrosine to the culture medium produced (1) a great decrease in the cell growth rate, (2) a loss of the anchorage-independent growth capacity, and (3) a change in the morphology of the cells to a...
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| Otros Autores: | , |
| Formato: | Capítulo de libro |
| Lenguaje: | Inglés |
| Publicado: |
1990
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| Acceso en línea: | Registro en Scopus DOI Handle Registro en la Biblioteca Digital |
| Aporte de: | Registro referencial: Solicitar el recurso aquí |
| LEADER | 05025caa a22007577a 4500 | ||
|---|---|---|---|
| 001 | PAPER-524 | ||
| 003 | AR-BaUEN | ||
| 005 | 20230518202952.0 | ||
| 008 | 190411s1990 xx ||||fo|||| 00| 0 eng|d | ||
| 024 | 7 | |2 scopus |a 2-s2.0-0025240033 | |
| 024 | 7 | |2 cas |a Melanins; Tyrosine, 55520-40-6 | |
| 040 | |a Scopus |b spa |c AR-BaUEN |d AR-BaUEN | ||
| 030 | |a ECREA | ||
| 100 | 1 | |a Guerra, L. | |
| 245 | 1 | 0 | |a Differentiating effect of l-tyrosine on the human melanoma cell line IIB-MEL-J |
| 260 | |c 1990 | ||
| 270 | 1 | 0 | |m Mordoh, J.; Instituto de Investigaciones Bioquimicas Luis F. Leloir Fundacion Campomar, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Av. Patricias Argentinas 435, 1405 Buenos Aires, Argentina |
| 506 | |2 openaire |e Política editorial | ||
| 504 | |a Greene, Clark, Jr., Tucker, Elder, Kramer, Du Pont, IV, Witmer, Fraser, (1985) N Engl. J. Med, 312, pp. 91-97 | ||
| 504 | |a Tranum, Dixon, Quagliana, (1987) Cancer Treat. Rep, 71, pp. 643-644 | ||
| 504 | |a Real, Fliegel, Houghton, (1988) Cancer Res, 48, pp. 686-693 | ||
| 504 | |a Pawelek, Bolognia, McLane, Murray, Osber, Slominski, (1988) Adv. Pigment Cell Res, pp. 143-154. , A. R. Liss, New York | ||
| 504 | |a Guerra, Mordoh, Slavutsky, Larripa, Medrano, (1989) Pigm. Cell Res, 2 (6), pp. 504-509 | ||
| 504 | |a Burnet, Seilter, Brown, (1967) Cancer Res, 27, pp. 880-887 | ||
| 504 | |a Pukel, Lloyd, Travassos, Dippold, Oettgen, Old, (1982) J. Exp. Med, 155, pp. 1133-1147 | ||
| 504 | |a Lerner, (1955) Methods in Enzymology, 2, pp. 827-831. , S.P. Colowick, N.O. Kaplan, Academic Press, New York | ||
| 504 | |a Laskin, Mufson, Weinstein, Engelhardt, (1980) J. Cell. Physiol, 103, pp. 467-474 | ||
| 504 | |a Shin, Freedman, Risser, Pollack, (1975) Proc. Natl. Acad. Sci. USA, 72, pp. 4435-4439 | ||
| 504 | |a Korner, Pawelek, (1982) Science, 217, pp. 1163-1165 | ||
| 504 | |a Bouchard, Vijayasaradhi, Houghton, (1989) Proc. Amer. Assoc. Cancer Res, 30, p. 352 | ||
| 504 | |a Buick, Pollack, (1984) Cancer Res, 44, pp. 4909-4918 | ||
| 520 | 3 | |a IIB-MEL-J is a highly heterogeneous newly established human melanoma cell line. The addition of 3 mM, l-tyrosine to the culture medium produced (1) a great decrease in the cell growth rate, (2) a loss of the anchorage-independent growth capacity, and (3) a change in the morphology of the cells to a fibroblastoid aspect. Coincident with these changes, an increase in subpopulations I and II and a decrease in subpopulations III and IV took place. In view of this evidence we consider that the cells have differentiated. The melanin production was not increased by the l-tyrosine treatment, suggesting that differentiation and melanin expression are not strictly correlated. © 1990. |l eng | |
| 536 | |a Detalles de la financiación: Universidad de Buenos Aires | ||
| 536 | |a Detalles de la financiación: This work has been supported by grants from the Consejo National de Investigaciones Cientificas y Tecnicas (CONICET), the Facultad de Ciencias Exactas y Naturales de la Universidad de Buenos Aires, the Fundacion Maria Calderon de la Barca, and the Fundacion para la Investigation de1 Cancer (FUCA). L.G. is a Fellow and J.M. is a Career Investigator of the CONICET. We are grateful to Dr. A. N. Houghton for the provision of the R24 monoclonal antibody. | ||
| 593 | |a Instituto de Investigaciones Bioquimicas Luis F. Leloir Fundacion Campomar, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Av. Patricias Argentinas 435, 1405 Buenos Aires, Argentina | ||
| 690 | 1 | 0 | |a MELANIN |
| 690 | 1 | 0 | |a TYROSINE |
| 690 | 1 | 0 | |a ARTICLE |
| 690 | 1 | 0 | |a CELL CULTURE |
| 690 | 1 | 0 | |a CELL DIFFERENTIATION |
| 690 | 1 | 0 | |a HUMAN |
| 690 | 1 | 0 | |a HUMAN CELL |
| 690 | 1 | 0 | |a MELANOMA CELL |
| 690 | 1 | 0 | |a PRIORITY JOURNAL |
| 690 | 1 | 0 | |a CELL ADHESION |
| 690 | 1 | 0 | |a CELL SEPARATION |
| 690 | 1 | 0 | |a CELL TRANSFORMATION, NEOPLASTIC |
| 690 | 1 | 0 | |a CENTRIFUGATION, DENSITY GRADIENT |
| 690 | 1 | 0 | |a HUMAN |
| 690 | 1 | 0 | |a LUNG NEOPLASMS |
| 690 | 1 | 0 | |a MELANINS |
| 690 | 1 | 0 | |a MELANOMA |
| 690 | 1 | 0 | |a MIDDLE AGE |
| 690 | 1 | 0 | |a SUPPORT, NON-U.S. GOV'T |
| 690 | 1 | 0 | |a TUMOR CELLS, CULTURED |
| 690 | 1 | 0 | |a TYROSINE |
| 700 | 1 | |a Bover, L. | |
| 700 | 1 | |a Mordoh, J. | |
| 773 | 0 | |d 1990 |g v. 188 |h pp. 61-65 |k n. 1 |p Exp. Cell Res. |x 00144827 |w (AR-BaUEN)CENRE-797 |t Experimental Cell Research | |
| 856 | 4 | 1 | |u https://www.scopus.com/inward/record.uri?eid=2-s2.0-0025240033&doi=10.1016%2f0014-4827%2890%2990278-I&partnerID=40&md5=396bfbd91a6ccdeab52e82650e4faf7e |y Registro en Scopus |
| 856 | 4 | 0 | |u https://doi.org/10.1016/0014-4827(90)90278-I |y DOI |
| 856 | 4 | 0 | |u https://hdl.handle.net/20.500.12110/paper_00144827_v188_n1_p61_Guerra |y Handle |
| 856 | 4 | 0 | |u https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00144827_v188_n1_p61_Guerra |y Registro en la Biblioteca Digital |
| 961 | |a paper_00144827_v188_n1_p61_Guerra |b paper |c PE | ||
| 962 | |a info:eu-repo/semantics/article |a info:ar-repo/semantics/artículo |b info:eu-repo/semantics/publishedVersion | ||
| 999 | |c 61477 | ||