Nitric oxide synthase I and VIP-activated signaling are affected in salivary glands of NOD mice
The autoimmune sialadenitis developed by non-obese diabetic (NOD) mice is considered a suitable model to study the ethiopathogenic mechanisms leading to sicca symptoms in Sjögren's syndrome (SS). Evidence supporting a neural rather than immune origin of the secretory dysfunction has been provid...
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2002
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| LEADER | 15449caa a22015857a 4500 | ||
|---|---|---|---|
| 001 | PAPER-5231 | ||
| 003 | AR-BaUEN | ||
| 005 | 20230518203452.0 | ||
| 008 | 190411s2002 xx ||||fo|||| 00| 0 eng|d | ||
| 024 | 7 | |2 scopus |a 2-s2.0-0036709645 | |
| 024 | 7 | |2 cas |a Nitric Oxide Synthase Type I, EC 1.14.13.39; Nitric Oxide Synthase, EC 1.14.13.39; Nitric Oxide, 10102-43-9; Nos1 protein, mouse, EC 1.14.13.39; Protein Isoforms; Receptors, Muscarinic; Vasoactive Intestinal Peptide, 37221-79-7 | |
| 040 | |a Scopus |b spa |c AR-BaUEN |d AR-BaUEN | ||
| 030 | |a JNRID | ||
| 100 | 1 | |a Rosignoli, F. | |
| 245 | 1 | 0 | |a Nitric oxide synthase I and VIP-activated signaling are affected in salivary glands of NOD mice |
| 260 | |c 2002 | ||
| 270 | 1 | 0 | |m Pérez Leirós, C.; Departamento de Quimica Biologica, Ciudad Universitaria, Pabellón II, 1428, Buenos Aires, Argentina; email: cpleiros@qb.fcen.uba.ar |
| 506 | |2 openaire |e Política editorial | ||
| 504 | |a Amin, A.R., Attur, M., Abramson, S.B., Nitric oxide synthase and cyclooxygenases: Distribution, regulation and intervention in arthritis (1999) Curr. Opin. Rheumatol., 11, pp. 202-209 | ||
| 504 | |a Bacman, S., Perez Leiros, C., Sterin-Borda, L., Hubscher, O., Arana, R., Borda, E., Autoantibodies against lacrimal gland M3 muscarinic acetylcholine receptors in patients with primary Sjögren's syndrome (1998) Invest. Ophthalmol. Visual Sci., 39, pp. 151-156 | ||
| 504 | |a Bernfeld, P., Amylase, alpha and beta (1955) Methods Enzymol., 1, pp. 149-158 | ||
| 504 | |a Borda, E.S., Pérez Leirós, C., Sterin Borda, L., Bracco, M.M.E., Cholinergic response of isolated rat atria to recombinant rat interferon-gamma (1991) J. Neuroimmunol., 32, pp. 53-59 | ||
| 504 | |a Colasanti, M., Cavalieri, E., Persichini, T., Mollace, V., Mariotto, S., Suzuki, H., Lauro, G.M., Bacterial lipopolysaccharide plus interferon-γ elicit a very fast inhibition of a Ca+2-dependent nitric oxide synthase activity in human astrocytoma cells (1997) J. Biol. Chem., 272, pp. 7582-7585 | ||
| 504 | |a Dawson, T.M., Snyder, S., Gases as biological messengers: Nitric oxide and carbon monoxide in the brain (1994) J. Neurosci., 14, pp. 5147-5159 | ||
| 504 | |a Dehaye, J.P., Christophe, J., Ernst, F., Poloczek, P., Van Bogaert, P., Binding in vitro of vasoactive intestinal peptide on isolated acini of rat parotid glands (1985) Arch. Oral Biol., 30, pp. 827-832 | ||
| 504 | |a Ekström, J., Mansson, B., Tobin, G., Vasoactive intestinal peptide induces salivary secretion in the rat (1982) J. Physiol. (Lond.), 332, p. 76 | ||
| 504 | |a Ekström, J., Mansson, B., Tobin, G., Vasoactive intestinal peptide evokes secretion of fluid and protein from rat salivary glands and the development of supersensitivity (1983) Acta Physiol. Scand., 119, pp. 169-175 | ||
| 504 | |a Förstermann, U., Boissel, J.P., Kleinert, H., Expressional control of the "constitutive" isoforms of nitric oxide synthase (NOS I and NOS III) (1998) FASEB J., 12, pp. 773-790 | ||
| 504 | |a Fox, R.I., Michelson, P., Approaches to the treatment of Sjögren's syndrome (2000) J. Rheumatol., 27, pp. 15-21 | ||
| 504 | |a Goetzl, E.J., Pankhaniya, R.R., Gaufo, G.O., Mu, Y., Xia, M., Sreedharan, S.P., Selectivity of effects of vasoactive intestinal peptide on macrophages and lymphocytes in compartmental immune responses (1998) Ann. N. Y. Acad. Sci. U.S.A., 840, pp. 540-550 | ||
| 504 | |a Goin, J.C., Perez Leiros, C., Borda, E., Sterin-Borda, L., Interaction of human chagasic IgG with the second extracellular loop of the human heart muscarinic acetylcholine receptor: Functional and pathological implications (1997) FASEB J., 10, pp. 77-83 | ||
| 504 | |a Hodges, R.H., Zoukhri, D., Sergheraert, C., Zieske, J.D., Dartt, D.A., Identification of vasoactive intestinal peptide receptor subtypes in the lacrimal gland and their signal-transducing components (1997) Invest. Ophthalmol. Visual Sci., 38, pp. 610-619 | ||
| 504 | |a Hu, Y., Nakagawa, Y., Purshotham, K., Humphreys-Beher, M.G., Functional changes in salivary glands of autoimmune disease-prone NOD mice (1992) Am. J. Physiol., 263, pp. E607-E614 | ||
| 504 | |a Hu, Y., Purushotham, K.R., Wang, P.L., Dawson, R., Humphreys-Beher, M.G., Down-regulation of β adrenergic receptors and signal transduction response in salivary glands of NOD mice (1994) Am. J. Physiol., 266, pp. G433-G443 | ||
| 504 | |a Humphreys-Beher, M.G., Hu, Y., Nakagawa, Y., Wang, P.L., Purushotham, K.R., Utilization of the NOD mouse as a model for the study of secondary Sjögren's syndrome (1994) Adv. Exp. Med. Biol., 350, pp. 631-637 | ||
| 504 | |a Inoue, Y., Kaku, K., Kaneko, T., Yanahara, N., Kanno, T., Vasoactive intestinal peptide binding to specific receptors on rat parotid acinar cells induces amylase secretion accompanied by cyclic adenosine 3′-5′-monophosphate (1985) Endocrinology, 116, pp. 686-692 | ||
| 504 | |a Jacobsson, L.T.H., Manthorpe, R., Epidemiology of Sjögren's syndrome (1995) Rheumatol. Eur., 24, pp. 46-47 | ||
| 504 | |a Kong, L., Robinson, C.P., Peck, A.B., Vela-Roch, N., Sakata, K.M., Dang, H., Talal, N., Humpherys-Beher, M.G., Inappropriate apoptosis of salivary and lacrimal gland epithelium of immunodeficient NOD-scid mice (1998) Clin. Exp. Rheumatol., 16, pp. 675-681 | ||
| 504 | |a Kontinnen, Y.T., Platts, L.A.M., Tuominen, S., Eklund, K.K., Santavirta, N., Törnwall, J., Sorsa, T., Polak, J.M., Role of nitric oxide in Sjögren's syndrome (1997) Arthritis Rheum., 40, pp. 875-883 | ||
| 504 | |a Lohinai, Z., Burghardt, B., Zelles, T., Varga, G., Nitric oxide modulates salivary amylase and fluid, but not epidermal growth factor secretion in conscious rats (1999) Life Sci., 64, pp. 953-963 | ||
| 504 | |a Lomniczi, A., Suburo, A.M., Elverdin, J.C., Mastronardi, C.A., Diaz, S., Rettori, V., McCann, S.M., Role of nitric oxide in salivary secretion (1998) Neuroimmunomodulation, 5, pp. 226-233 | ||
| 504 | |a Lowry, O.H., Rosebrough, N.J., Farr, A.L., Randall, R.J., Protein measurement with the Folin phenol reagent (1951) J. Biol. Chem., 193, pp. 265-275 | ||
| 504 | |a Lundberg, J.M., Anggard, A., Fahrenkrug, J., Complementary role of vasoactive intestinal polypeptide (VIP) and acetylcholine for cat submandibular gland blood flow and secretion (1982) Acta Physiol. Scand., 114, pp. 329-337 | ||
| 504 | |a Mitsui, Y., Furuyama, S., Characterization of nitric oxide synthase in the rat parotid gland (2000) Arch. Oral Biol., 45, pp. 531-536 | ||
| 504 | |a Miyagawa, J., Ultrastructural and immunocytochemical submandibulitis in the non-obese diabetic (NOD) mouse (1986) Virchows Arch. (Cell. Pathol.), 51, pp. 215-225 | ||
| 504 | |a Moncada, S., Palmer, R.M.J., Higgs, E.A., Nitric oxide physiology, pathophysiology and pharmacology (1991) Pharmacol. Rev., 43, pp. 109-142 | ||
| 504 | |a Murthy, K.S., Zhang, K.-M., Jin, J.G., Grider, J.R., Makhlouf, G.M., VIP-mediated G protein-coupled Ca+2 influx activates a constitutive NOS in dispersed gastric muscle cells (1993) Am. J. Physiol., 265, pp. G660-G671 | ||
| 504 | |a Nathan, C., Xie, Q.W., Regulation of biosynthesis of nitric oxide (1994) J. Biol. Chem., 269, pp. 13725-13728 | ||
| 504 | |a Perez Leiros, C., Goren, N., Sterin-Borda, L., Lustig, L., Borda, E.S., Alterations in cardiac muscarinic acetylcholine receptors in mice with autoimmune myocarditis and association with circulating muscarinic receptor-related autoantibodies (1994) Clin. Aut. Res., 4, pp. 249-255 | ||
| 504 | |a Pérez Leirós, C., Sterin Borda, L., Borda, E.S., Goin, J.C., Hosey, M.M., Desensitization and sequestration of human m2 muscarinic acetylcholine receptors by autoantibodies from patients with Chagas' disease (1997) J. Biol. Chem., 272, pp. 12989-12993 | ||
| 504 | |a Perez Leiros, C., Goren, N., Sterin-Borda, L., Borda, E.S., Myocardial Dysfunction in an experimental model of autoimmune myocarditis: Role of IFN gamma (1998) Neuroimmunomodulation, 4, pp. 91-97 | ||
| 504 | |a Perez Leiros, C., Sterin-Borda, L., Hubscher, O., Arana, R., Borda, E., Activation of nitric oxide signaling through muscarinic receptors in submandibular glands by primary Sjögren's syndrome antibodies (1999) Clin. Immunol., 90, pp. 190-195 | ||
| 504 | |a Perez Leiros, C., Rosignoli, F., Genaro, A.M., Sales, M.E., Sterin-Borda, L., Borda, E.S., Differential activation of nitric oxide synthase through muscarinic acetylcholine receptors in rat salivary glands (2000) J. Aut. Nerv. Syst., 79, pp. 99-107 | ||
| 504 | |a Pozo, D., Delgado, M., Martínez, C., Guerrero, J.M., Leceta, J., Gomariz, R., Calvo, J.R., Immunobiology of vasoactive intestinal peptide (VIP) (2000) Immunol. Today, 21, pp. 7-11 | ||
| 504 | |a Robberecht, P., Waelbroeck, M., A critical view of the methods for characterization of the VIP/PACAP receptor subclasses (1998) Ann. N. Y. Acad. Sci., 865, pp. 157-163 | ||
| 504 | |a Roitt, I.M., Brostoff, J., Male, D., Autoimmunity and autoimmune disease (1998) Immunology, pp. 367-380. , London: Mosby International | ||
| 504 | |a Rosignoli, F., Goren, N., Perez Leiros, C., Alterations in nitric oxide synthase activity and expression in submandibular glands of NOD mice (2001) Clin. Immunol., 101, pp. 86-93 | ||
| 504 | |a Rosignoli, F., Pérez Leirós, C., Activation of nitric oxide synthase through muscarinic receptors in rat parotid gland (2002) Eur. J. Pharmacol., 439, pp. 27-33 | ||
| 504 | |a Sterin-Borda, L., Pérez Leirós, C., Borda, E.S., Bracco, M.M.E., Effects of IL2 on the myocardium. Participation of the sympathetic system (1996) J. Mol. Cell. Cardiol., 28, pp. 2457-2465 | ||
| 504 | |a Strand, V., Talal, N., Advances in the diagnosis and concept of Sjögren's syndrome (autoimmune exocrinopathy) (1980) Bull. Rheum. Dis., 92, pp. 212-226 | ||
| 504 | |a Turner, J.T., Bylund, D.B., Characterization of the vasoactive intestinal peptide receptor in rat submandibular gland: Radioligand binding assay in membrane preparations (1987) J. Pharmacol. Exp. Ther., 242, pp. 873-881 | ||
| 504 | |a Turner, J.T., Camden, J.M., Regulation of secretion by vasoactive intestinal peptide in isolated perfused rat submandibular glands (1992) Arch. Oral Biol., 37, pp. 281-287 | ||
| 504 | |a Yamamoto, H., Sims, N.E., Macauley, S.P., Nguyen, K.H.T., Nakagawa, Y., Humphreys-Beher, M.G., Alterations in the secretory response of non-obese diabetic (NOD) mice to muscarinic receptor stimulation (1996) Clin. Immunol. Immunopathol., 78, pp. 245-255 | ||
| 504 | |a Yamamoto, H., Ishibashi, K., Nakagawa, Y., Maeda, N., Zeng, T., Robinson, C.P., Oxford, G.E., Humphreys-Beher, M.G., Detection of alterations in the levels of neuropeptides and salivary gland responses in the non-obese diabetic mouse model for autoimmune sialoadenitis (1997) Scand. J. Immunol., 45, pp. 55-61 | ||
| 504 | |a Yamano, S., Atkinson, J.C., Baum, B.J., Fox, P.C., Salivary gland cytokine expression in NOD and normal BALB/c mice (1999) Clin. Immunol., 92, pp. 265-275 | ||
| 520 | 3 | |a The autoimmune sialadenitis developed by non-obese diabetic (NOD) mice is considered a suitable model to study the ethiopathogenic mechanisms leading to sicca symptoms in Sjögren's syndrome (SS). Evidence supporting a neural rather than immune origin of the secretory dysfunction has been provided. As both nitric oxide and vasoactive intestinal peptide (VIP) are common messengers to nervous and immune systems mediating secretory and inflammatory responses, we examined nitric oxide synthase (NOS) activity with special focus on VIP-mediated effects in salivary glands of NOD mice. We found a decreased NOS activity and expression in major salivary glands of NOD mice with respect to control mice. In addition, there was a deficient VIP-activated signaling associated with a reduced saliva and amylase secretion in response to VIP. Our results support the hypothesis of an impaired balance of neuroimmune interactions in salivary glands as early events to take place in the progressive loss of secretory function of NOD mice. © 2002 Elsevier Science B.V. All rights reserved. |l eng | |
| 536 | |a Detalles de la financiación: Ministerio de Salud de la Nación, MSAL, 2000-2002 | ||
| 536 | |a Detalles de la financiación: Fundación Alberto J. Roemmers | ||
| 536 | |a Detalles de la financiación: This work was supported by grants “Beca Ramón Carrillo-Arturo Oñativia” 2000 and 2001 from Ministerio de Salud of Argentina and grant 2000-2002 from Fundación Alberto J. Roemmers. We wish to thank Dr. Livia Lustig for histological studies of NOD salivary glands and Mrs. Micaela Ricca for expert technical assistance in NOD mice management. | ||
| 593 | |a Departamento de Química Biológica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires-CONICET, Buenos Aires, Argentina | ||
| 593 | |a Departamento de Qu, Ciudad Universitaria, Buenos Aires, Argentina | ||
| 690 | 1 | 0 | |a AUTOIMMUNE SIALADENITIS |
| 690 | 1 | 0 | |a NITRIC OXIDE |
| 690 | 1 | 0 | |a NOD MICE |
| 690 | 1 | 0 | |a NOS ISOFORMS |
| 690 | 1 | 0 | |a SALIVARY GLANDS |
| 690 | 1 | 0 | |a VIP SIGNALING |
| 690 | 1 | 0 | |a AMYLASE |
| 690 | 1 | 0 | |a NITRIC OXIDE SYNTHASE |
| 690 | 1 | 0 | |a VASOACTIVE INTESTINAL POLYPEPTIDE |
| 690 | 1 | 0 | |a AMYLASE RELEASE |
| 690 | 1 | 0 | |a ANIMAL EXPERIMENT |
| 690 | 1 | 0 | |a ANIMAL MODEL |
| 690 | 1 | 0 | |a ANIMAL TISSUE |
| 690 | 1 | 0 | |a ARTICLE |
| 690 | 1 | 0 | |a CONTROLLED STUDY |
| 690 | 1 | 0 | |a DIABETES MELLITUS |
| 690 | 1 | 0 | |a ENZYME ACTIVATION |
| 690 | 1 | 0 | |a ENZYME ACTIVITY |
| 690 | 1 | 0 | |a ENZYME RELEASE |
| 690 | 1 | 0 | |a IMMUNE SYSTEM |
| 690 | 1 | 0 | |a INFLAMMATION |
| 690 | 1 | 0 | |a MOUSE |
| 690 | 1 | 0 | |a NERVOUS SYSTEM |
| 690 | 1 | 0 | |a NONHUMAN |
| 690 | 1 | 0 | |a PAROTID GLAND |
| 690 | 1 | 0 | |a PATHOGENESIS |
| 690 | 1 | 0 | |a PRIORITY JOURNAL |
| 690 | 1 | 0 | |a PROTEIN DEFICIENCY |
| 690 | 1 | 0 | |a PROTEIN EXPRESSION |
| 690 | 1 | 0 | |a PROTEIN SECRETION |
| 690 | 1 | 0 | |a SALIVA LEVEL |
| 690 | 1 | 0 | |a SALIVATION |
| 690 | 1 | 0 | |a SIALOADENITIS |
| 690 | 1 | 0 | |a SIGNAL TRANSDUCTION |
| 690 | 1 | 0 | |a SJOEGREN SYNDROME |
| 690 | 1 | 0 | |a SUBMANDIBULAR GLAND |
| 690 | 1 | 0 | |a AGE FACTORS |
| 690 | 1 | 0 | |a ANIMALS |
| 690 | 1 | 0 | |a FEMALE |
| 690 | 1 | 0 | |a MALE |
| 690 | 1 | 0 | |a MICE |
| 690 | 1 | 0 | |a MICE, INBRED BALB C |
| 690 | 1 | 0 | |a MICE, INBRED NOD |
| 690 | 1 | 0 | |a NEUROIMMUNOMODULATION |
| 690 | 1 | 0 | |a NITRIC OXIDE |
| 690 | 1 | 0 | |a NITRIC OXIDE SYNTHASE |
| 690 | 1 | 0 | |a NITRIC OXIDE SYNTHASE TYPE I |
| 690 | 1 | 0 | |a PARASYMPATHETIC FIBERS, POSTGANGLIONIC |
| 690 | 1 | 0 | |a PROTEIN ISOFORMS |
| 690 | 1 | 0 | |a RECEPTORS, MUSCARINIC |
| 690 | 1 | 0 | |a SALIVARY GLANDS |
| 690 | 1 | 0 | |a SIGNAL TRANSDUCTION |
| 690 | 1 | 0 | |a SJOGREN'S SYNDROME |
| 690 | 1 | 0 | |a VASOACTIVE INTESTINAL PEPTIDE |
| 650 | 1 | 7 | |2 spines |a SALIVA |
| 700 | 1 | |a Pérez Leirós, C. | |
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