Modulation of ACh release by presynaptic muscarinic autoreceptors in the neuromuscular junction of the newborn and adult rat
We studied the presynaptic muscarinic autoreceptor subtypes controlling ACh release and their relationship with voltage-dependent calcium channels in the neuromuscular synapses of the Levator auris longus muscle from adult (30-40 days) and newborn (3-6 and 15 days postnatal) rats. Using intracellula...
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| Formato: | Capítulo de libro |
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2003
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| LEADER | 16344caa a22018017a 4500 | ||
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| 001 | PAPER-5073 | ||
| 003 | AR-BaUEN | ||
| 005 | 20230518203441.0 | ||
| 008 | 190411s2003 xx ||||fo|||| 00| 0 eng|d | ||
| 024 | 7 | |2 scopus |a 2-s2.0-0037234739 | |
| 024 | 7 | |2 cas |a acetylcholine, 51-84-3, 60-31-1, 66-23-9; methoctramine, 104807-46-7; nitrendipine, 39562-70-4; omega conotoxin GVIA, 107407-86-3; pirenzepine, 28797-61-7, 29868-97-1; tropicamide, 1508-75-4; Acetylcholine, 51-84-3; Autoreceptors; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Calcium Channels, N-Type; Calcium Channels, P-Type; Calcium Channels, Q-Type; Diamines; methoctramine, 104807-46-7; Muscarinic Antagonists; Nitrendipine, 39562-70-4; omega-Agatoxin IVA; omega-Conotoxin GVIA, 92078-76-7; Pirenzepine, 28797-61-7; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptor, Muscarinic M4; Receptors, Muscarinic | |
| 040 | |a Scopus |b spa |c AR-BaUEN |d AR-BaUEN | ||
| 030 | |a EJONE | ||
| 100 | 1 | |a Santafé, M.M. | |
| 245 | 1 | 0 | |a Modulation of ACh release by presynaptic muscarinic autoreceptors in the neuromuscular junction of the newborn and adult rat |
| 260 | |c 2003 | ||
| 270 | 1 | 0 | |m Santafé, M.M.; Unitat d'Histologia i Neurobiologia, Facultat de Med. i C. de la S., Universitat Rovira i Virgili, carrer St Llorenç num 21, 43201-Reus, Spain; email: msm@fmcs.urv.es |
| 506 | |2 openaire |e Política editorial | ||
| 504 | |a Abbs, E.T., Joseph, D.N., The effects of atropine and oxotremorine on acetylcholine release in rat phrenic nerve-diaphragm preparations (1981) Br. J. Pharmacol., 73, pp. 481-483 | ||
| 504 | |a Allen, T.G.J., The role of N-, Q- and R-type Ca2+ channels in feedback inhibition of ACh release from rat basal forebrain neurones (1999) J. Physiol. (Lond.), 515, pp. 93-107 | ||
| 504 | |a Allen, T.G.J., Brown, D.A., M2 muscarinic receptor mediated inhibition of the Ca2+ current in rat magnocellular cholinergic basal forebrain neurones (1993) J. Physiol. (Lond.), 466, pp. 173-189 | ||
| 504 | |a Allen, T.G.J., Sim, J.A., Brown, D.A., The whole-cell calcium current in acutely dissociated magnocellular cholinergic basal forebrain neurones of the rat (1993) J. Physiol. (Lond.), 460, pp. 91-116 | ||
| 504 | |a Arellano, R.O., Garay, E., Miledi, R., Muscarinic receptor heterogeneity in follicle-enclosed Xenopus oocytes (1999) J. Physiol. (Lond.), 521, pp. 409-419 | ||
| 504 | |a Arenson, M.S., Muscarinic inhibition of quantal transmitter release from the magnesium-paralysed frog sartorius muscle (1989) Neuroscience, 30, pp. 827-836 | ||
| 504 | |a Atchison, W.D., Dihydropyridine-sensitive and -insensitive components of acetylcholine release from rat motor nerve terminals (1989) J. Pharmacol. Exp. Ther., 251, pp. 672-678 | ||
| 504 | |a Benoit, P., Changeux, J.P., Consequences of tenotomy on the evolution of multiinnervation in developing rat soleus muscle (1975) Brain Res., 99, pp. 354-358 | ||
| 504 | |a Bowersox, S.S., Miljanich, G.P., Sugiura, Y., Li, C., Nadasdi, L., Hoffman, B.B., Ramachandran, J., Ko, C.-P., Differential blockade of voltage-sensitive calcium channels at the mouse neuromuscular junction by novel ω-conopeptides and ω-agatoxin-IVA (1995) J. Pharmacol. Exp. Ther., 273, pp. 248-256 | ||
| 504 | |a Caulfield, M.P., Muscarinic receptors - Characterization, coupling and function (1993) Pharmacol. Therap., 58, pp. 319-379 | ||
| 504 | |a Caulfield, M.P., Birdsall, N.M.J., Classification of muscarine acetylcholine receptors (1998) Pharmacol. Rev., 50, pp. 279-290 | ||
| 504 | |a Day, N.C., Wood, S.J., Ince, P.G., Volsen, S.G., Smith, W., Slater, C.R., Shaw, P.J., Differential localization of voltage-dependent calcium channel α1 subunits at the human and rat neuromuscular junction (1997) J. Neurosci., 17, pp. 6226-6235 | ||
| 504 | |a Dennis, M.J., Ziskind-Conhaim, L., Harris, A.J., Development of neuromuscular junctions in rat embryos (1981) Dev. Biol., 81, pp. 266-279 | ||
| 504 | |a Dolezal, V., Túcek, S., Presynaptic muscarinic receptors and the release of acetylcholine from cortical prisms: Roles of Ca2+ and K+ concentration (1993) Naunyn-Schmiedeberg's Arch. Pharmacol., 348, pp. 228-233 | ||
| 504 | |a Felder, C.C., Muscarinic acetylcholine receptors: Signal transduction through multiple effects (1995) FASEB J., 9, pp. 619-625 | ||
| 504 | |a Ganguly, D.K., Das, M., Effects of oxotremorine demonstrate pre-synaptic muscarinic and dopaminergic receptors on motor nerve terminals (1979) Nature, 278, pp. 645-646 | ||
| 504 | |a Hamilton, B.R., Smith, D.O., Autoreceptor-modulated purinergic and cholinergic inhibition of motor nerve terminal calcium currents in the rat (1991) J. Physiol. (Lond.), 432, pp. 327-341 | ||
| 504 | |a Hong, S.J., Chang, C.C., Inhibition of acetylcholine release from mouse motor nerve by a P-type calcium channel blocker, ω-Agatoxin IVA (1995) J. Physiol. (Lond.), 482, pp. 283-290 | ||
| 504 | |a Hsu, K.S., Huang, C.C., Gean, P.W., Muscarinic depression of excitatory synaptic transmission mediated by the presynaptic M3 receptors in the rat neostriatum (1995) Neurosci. Lett., 197, pp. 141-144 | ||
| 504 | |a Hubbard, J.J., Wilson, D.F., Neuromuscular transmission in a mammalian preparation in absence of the blocking drugs and the effect of D-tubocurarine (1973) J. Physiol. (Lond.), 228, pp. 307-327 | ||
| 504 | |a Iwasaki, S., Momiyama, A., Uchitel, O.D., Takahashi, T., Developmental changes in calcium channel types mediating central synaptic transmission (2000) J. Neurosci., 20, pp. 59-65 | ||
| 504 | |a Jansen, J.K.S., Fladby, T., The perinatal reorganization of the innervation of skeletal muscle in mammals (1990) Prog. Neurobiol., 34, pp. 39-90 | ||
| 504 | |a Katz, B., Miledi, R., Further study of the role of calcium in synaptic transmission (1970) J. Physiol. (Lond.), 207, pp. 789-801 | ||
| 504 | |a Katz, B., Miledi, R., Transmitter leakage from motor nerve endings (1977) Proc. R. Soc. B, 196, pp. 59-72 | ||
| 504 | |a Kerr, L.M., Yoshikami, D., A venom peptide with a novel presynaptic blocking action (1984) Nature, 308, pp. 282-284 | ||
| 504 | |a Margeta-Mitrovic, M., Grigg, J.J., Koyano, K., Nakajima, Y., Nakajima, S., Neurotensin and substance P inhibit low- and high-voltage-activated Ca2+ channels in cultured newborn rat nucleus basalis neurons (1997) J. Neurophysiol., 78, pp. 1341-1352 | ||
| 504 | |a McLachlan, E.M., Martin, A.R., Non-linear summation of end-plate potentials in the frog and mouse (1981) J. Physiol. (Lond.), 311, pp. 307-324 | ||
| 504 | |a Minic, J., Molgo, J., Karlsson, E., Krejci, E., Regulation of acetylcholine release by muscarinic receptors at the mouse neuromuscular junction depends on the activity of acetylcholinesterase (2002) Eur. J. Neurosci., 15, pp. 439-448 | ||
| 504 | |a Mintz, I.M., Sabatini, B.L., Regehr, W.G., Calcium control of transmitter release at a cerebellar synapse (1995) Neuron, 15, pp. 675-688 | ||
| 504 | |a Muller, D., Loctin, F., Dunant, Y., Inhibition of evoked acetylcholine release: Two different mechanisms in the Torpedo electric organ (1987) Eur. J. Pharmacol., 33, pp. 225-234 | ||
| 504 | |a Nathanson, N.M., A multiplicity of muscarinic mechanisms: Enough signaling pathways to take your breath away (2000) Proc. Natl. Acad. Sci. USA, 97, pp. 6245-6247 | ||
| 504 | |a O'Brien, R.A.D., Ostberg, A.J.C., Vrbovà, G., Observations on the elimination of polyneuronal innervation in developing mammalian skeletal muscle (1978) J. Physiol. (Lond.), 282, pp. 571-582 | ||
| 504 | |a Penner, R., Dreyer, F., Two different presynaptic calcium currents in mouse motor nerve terminals (1986) Pflügers Arch., 406, pp. 190-197 | ||
| 504 | |a Protti, D.A., Szczupak, L., Scornik, F.S., Uchitel, O.D., Effect of ω-conotoxin GVIA on neurotransmitter releases at the mouse neuromuscular junction (1991) Brain Res., 557, pp. 336-339 | ||
| 504 | |a Protti, D., Uchitel, O.D., P/Q-type calcium channels activate neighboring calcium-dependent potassium channels in mouse motor nerve terminals (1993) Pflügers Arch., 434, pp. 496-412 | ||
| 504 | |a Ren, J., Harty, R.F., Presynaptic muscarinic receptors modulate acetylcholine release from rat antral mucosal/submucosal nerves (1994) Digest. Dis. Sci., 39, pp. 1099-1106 | ||
| 504 | |a Robitaille, R., Jahromi, B.S., Charlton, M.P., Muscarinic Ca2+ responses resistant to muscarinic antagonists at presynaptic Schwann cells of the frog neuromuscular junctions (1997) J. Physiol. (Lond.), 504, pp. 337-347 | ||
| 504 | |a Rosato-Siri, M.D., Uchitel, O.D., Calcium channels coupled to neurotransmitter release at neonatal rat neuromuscular junctions (1999) J. Physiol. (Lond.), 514, pp. 533-540 | ||
| 504 | |a Rouse, S.T., Levey, A.I., Muscarinic acetylcholine receptor immunoreactivity after hippocampal commissural/associational pathway lesions: Evidence for multiple presynaptic receptor subtypes (1997) J. Comp. Neurol., 380, pp. 382-394 | ||
| 504 | |a Santafé, M.M., Garcia, N., Lanuza, M.A., Uchitel, O.D., Tomàs, J., Calcium channels coupled to neurotransmitter release at dually innervated neuromuscular junctions in the newborn rat (2001) Neuroscience, 102, pp. 697-708 | ||
| 504 | |a Slutsky, I., Parnas, H., Parnas, I., Presynaptic effects of muscarine on ACh release at the frog neuromuscular junction (1999) J. Physiol. (Lond.), 514, pp. 769-782 | ||
| 504 | |a Starke, K., Göthert, M., Kilbinger, H., Modulation of neurotransmitter release by presynaptic autoreceptors (1989) Physiol. Rev., 69, pp. 864-989 | ||
| 504 | |a Uchitel, O.D., Protti, D.A., Sánchez, V., Cherksey, B.D., Sugimori, M., Llinás, R., P-type voltage-dependent calcium channel mediates presynaptic calcium influx and transmitter release in mammalian synapses (1992) Proc. Natl. Acad. Sci. USA, 89, pp. 3330-3333 | ||
| 504 | |a Vannucchi, M.G., Pepeu, G., Muscarinic receptor modulation of acetylcholine release from rat cerebral cortex and hippocampus (1995) Neurosci. Lett., 190, pp. 53-56 | ||
| 504 | |a Wanke, E., Ferroni, A., Malgaroli, A., Ambrosini, A., Pozann, T., Meldolesi, J., Activation of muscarinic receptor selectively inhibits a rapidly inactivated Ca2+ current in rat sympathetic neurons (1987) Proc. Natl. Acad. Sci. USA, 84, pp. 4313-4317 | ||
| 504 | |a Wessler, I., Karl, M., Mai, M., Diener, A., Muscarine receptors on the rat phrenic nerve, evidence for positive and negative muscarinic feedback mechanisms (1987) Naunyn-Schmiedeberg's Arch. Pharmacol., 335, pp. 605-612 | ||
| 504 | |a Westenbroek, R.E., Hoskins, L., Catterall, W.A., Localization of Ca2+ channel subtypes on rat spinal motor neurons, interneurons, and nerve terminals (1998) J. Neurosci., 18, pp. 6319-6330 | ||
| 504 | |a Williams, S., Serafin, M., Muhlethaler, M., Bernheim, L., Distinct contributions of high- and low-voltage-activated calcium currents to after-hyperpolarizations in cholinergic nucleus basalis neurons of the guinea pig (1997) J. Neurosci., 17, pp. 7307-7315 | ||
| 520 | 3 | |a We studied the presynaptic muscarinic autoreceptor subtypes controlling ACh release and their relationship with voltage-dependent calcium channels in the neuromuscular synapses of the Levator auris longus muscle from adult (30-40 days) and newborn (3-6 and 15 days postnatal) rats. Using intracellular recording, we studied how several muscarinic antagonists affected the evoked endplate potentials. In some experiments we previously incubated the muscle with calcium channel blockers (nitrendipine, ω-conotoxin-GVIA and ω-Agatoxin-IVA) before determining the muscarinic response. In the adult, the M1 receptor-selective antagonist pirenzepine (10 μM) reduced evoked neurotransmission (≈47%). The M2 receptor-selective antagonist methoctramine (1 μM) increased the evoked release (≈67%). Both M1- and M2-mediated mechanisms depend on calcium influx via P/Q-type synaptic channels. We found nothing to indicate the presence of M3 (4-DAMP-sensitive) or M4 (tropicamide-sensitive) receptors in the muscles of adult or newborn rats. In the 3-6-day newborn rats, pirenzepine reduced the evoked release (≈30%) by a mechanism independent of L-, N- and P/Q-type calcium channels, and the M2 antagonist methoctramine (1 μM) unexpectedly decreased the evoked release (≈40%). This methoctramine effect was a P/Q-type calcium-channel-dependent mechanism. However, upon maturation in the first two postnatal weeks, the M2 pathway shifted to perform the calcium-dependent release-inhibitory activity found in the adult. We show that the way in which M1 and M2 muscarinic receptors modulate neurotransmission can differ between the developing and adult rat neuromuscular synapse. |l eng | |
| 593 | |a Unitat d'Histologia i Neurobiologia, Facultat de Med. i C. de la S., Universitat Rovira i Virgili, carrer St Llorenç num 21, 43201-Reus, Spain | ||
| 593 | |a Lab. de Fisiol./Biol. Molec./Celular, Fac. de Ciencias Exactas y Naturales, Universidad de Buenos Aires, 1428-Buenos Aires, Argentina | ||
| 690 | 1 | 0 | |a CALCIUM CHANNELS |
| 690 | 1 | 0 | |a CHOLINERGIC SYNAPSES |
| 690 | 1 | 0 | |a MOTOR END-PLATE |
| 690 | 1 | 0 | |a MOTOR NERVE TERMINAL |
| 690 | 1 | 0 | |a 1,1 DIMETHYL 4 DIPHENYLACETOXYPIPERIDINIUM IODIDE |
| 690 | 1 | 0 | |a ACETYLCHOLINE |
| 690 | 1 | 0 | |a AUTORECEPTOR |
| 690 | 1 | 0 | |a CALCIUM CHANNEL L TYPE |
| 690 | 1 | 0 | |a CALCIUM CHANNEL N TYPE |
| 690 | 1 | 0 | |a CALCIUM CHANNEL P TYPE |
| 690 | 1 | 0 | |a CALCIUM CHANNEL Q TYPE |
| 690 | 1 | 0 | |a METHOCTRAMINE |
| 690 | 1 | 0 | |a MUSCARINIC M1 RECEPTOR |
| 690 | 1 | 0 | |a MUSCARINIC M2 RECEPTOR |
| 690 | 1 | 0 | |a MUSCARINIC M3 RECEPTOR |
| 690 | 1 | 0 | |a MUSCARINIC M4 RECEPTOR |
| 690 | 1 | 0 | |a NITRENDIPINE |
| 690 | 1 | 0 | |a OMEGA AGATOXIN VIA |
| 690 | 1 | 0 | |a OMEGA CONOTOXIN GVIA |
| 690 | 1 | 0 | |a PIPERIDINE DERIVATIVE |
| 690 | 1 | 0 | |a PIRENZEPINE |
| 690 | 1 | 0 | |a TROPICAMIDE |
| 690 | 1 | 0 | |a UNCLASSIFIED DRUG |
| 690 | 1 | 0 | |a ACETYLCHOLINE RELEASE |
| 690 | 1 | 0 | |a ANIMAL TISSUE |
| 690 | 1 | 0 | |a ARTICLE |
| 690 | 1 | 0 | |a CALCIUM TRANSPORT |
| 690 | 1 | 0 | |a CONTROLLED STUDY |
| 690 | 1 | 0 | |a DOSE RESPONSE |
| 690 | 1 | 0 | |a DRUG EFFECT |
| 690 | 1 | 0 | |a ELECTROPHYSIOLOGY |
| 690 | 1 | 0 | |a MINIATURE ENDPLATE POTENTIAL |
| 690 | 1 | 0 | |a MUSCLE CONTRACTION |
| 690 | 1 | 0 | |a NEUROMUSCULAR SYNAPSE |
| 690 | 1 | 0 | |a NEUROTRANSMISSION |
| 690 | 1 | 0 | |a NEWBORN |
| 690 | 1 | 0 | |a NONHUMAN |
| 690 | 1 | 0 | |a PERINATAL PERIOD |
| 690 | 1 | 0 | |a PRESYNAPTIC NERVE |
| 690 | 1 | 0 | |a PRIORITY JOURNAL |
| 690 | 1 | 0 | |a RAT |
| 690 | 1 | 0 | |a ACETYLCHOLINE |
| 690 | 1 | 0 | |a AGING |
| 690 | 1 | 0 | |a ANIMALS |
| 690 | 1 | 0 | |a ANIMALS, NEWBORN |
| 690 | 1 | 0 | |a AUTORECEPTORS |
| 690 | 1 | 0 | |a CALCIUM CHANNEL BLOCKERS |
| 690 | 1 | 0 | |a CALCIUM CHANNELS |
| 690 | 1 | 0 | |a CALCIUM CHANNELS, L-TYPE |
| 690 | 1 | 0 | |a CALCIUM CHANNELS, N-TYPE |
| 690 | 1 | 0 | |a CALCIUM CHANNELS, P-TYPE |
| 690 | 1 | 0 | |a CALCIUM CHANNELS, Q-TYPE |
| 690 | 1 | 0 | |a DIAMINES |
| 690 | 1 | 0 | |a ELECTROPHYSIOLOGY |
| 690 | 1 | 0 | |a MOTOR ENDPLATE |
| 690 | 1 | 0 | |a MUSCARINIC ANTAGONISTS |
| 690 | 1 | 0 | |a MUSCLE, SKELETAL |
| 690 | 1 | 0 | |a NEUROMUSCULAR JUNCTION |
| 690 | 1 | 0 | |a NITRENDIPINE |
| 690 | 1 | 0 | |a OMEGA-AGATOXIN IVA |
| 690 | 1 | 0 | |a OMEGA-CONOTOXIN GVIA |
| 690 | 1 | 0 | |a PIRENZEPINE |
| 690 | 1 | 0 | |a PRESYNAPTIC TERMINALS |
| 690 | 1 | 0 | |a RATS |
| 690 | 1 | 0 | |a RATS, SPRAGUE-DAWLEY |
| 690 | 1 | 0 | |a RECEPTOR, MUSCARINIC M1 |
| 690 | 1 | 0 | |a RECEPTOR, MUSCARINIC M2 |
| 690 | 1 | 0 | |a RECEPTOR, MUSCARINIC M3 |
| 690 | 1 | 0 | |a RECEPTOR, MUSCARINIC M4 |
| 690 | 1 | 0 | |a RECEPTORS, MUSCARINIC |
| 690 | 1 | 0 | |a SYNAPTIC TRANSMISSION |
| 700 | 1 | |a Salon, I. | |
| 700 | 1 | |a Garcia, N. | |
| 700 | 1 | |a Lanuza, M.A. | |
| 700 | 1 | |a Uchitel, O.D. | |
| 700 | 1 | |a Tomàs, J. | |
| 773 | 0 | |d 2003 |g v. 17 |h pp. 119-127 |k n. 1 |p Eur. J. Neurosci. |x 0953816X |w (AR-BaUEN)CENRE-4671 |t European Journal of Neuroscience | |
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