Dynamic rheological measurements and drug release kinetics in swollen scleroglucan matrices
The structure of scleroglucan gel matrices was characterized by dynamic rheological studies. The results were compared with the release kinetics of theophylline in analogous samples using a Franz diffusion cell, fitting the drug release data with a semi-empirical power law. Dynamic rheology gave inf...
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| Formato: | Capítulo de libro |
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Elsevier
2003
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| Acceso en línea: | Registro en Scopus DOI Handle Registro en la Biblioteca Digital |
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| LEADER | 08021caa a22008777a 4500 | ||
|---|---|---|---|
| 001 | PAPER-4901 | ||
| 003 | AR-BaUEN | ||
| 005 | 20250328094458.0 | ||
| 008 | 190411s2003 xx ||||fo|||| 00| 0 eng|d | ||
| 024 | 7 | |2 scopus |a 2-s2.0-0038783259 | |
| 024 | 7 | |2 cas |a scleroglucan, 39464-87-4; theophylline, 58-55-9, 5967-84-0, 8055-07-0, 8061-56-1, 99007-19-9 | |
| 030 | |a JCREE | ||
| 040 | |a Scopus |b spa |c AR-BaUEN |d AR-BaUEN | ||
| 100 | 1 | |a François, Nora Judith | |
| 245 | 1 | 0 | |a Dynamic rheological measurements and drug release kinetics in swollen scleroglucan matrices |
| 260 | |b Elsevier |c 2003 | ||
| 270 | 1 | 0 | |m Bernik, D.L.; Inst. Quim. Fis. Mat., Ambiente y E., INQUIMAE, Universidad de Buenos Aires, 3er Piso, C1428EHA Buenos Aires, Argentina; email: dbernik@qi.fcen.uba.ar |
| 504 | |a De Nooy, E.J., Rori, V., Masci, G., Dentini, M., Crescenzi, V., Synthesis and preliminary characterization of charged derivatives and hydrogels from scleroglucan (2000) Carbohydrate Res., 324, pp. 116-126. , and Refs. therein | ||
| 504 | |a Norisuye, T., Yanaki, T., Fujita, H., Dynamics during thermoreversible gelation of the polysaccharide Schizophyllan (1980) J. Polym. Sci. Polym. Phys. Ed., 18, pp. 547-558 | ||
| 504 | |a Daraio, M.E., François, N.J., Bernik, D.L., Correlation between gel structural properties and drug release pattern in scleroglucan matrices (2003) Drug Delivery, 10 (2), pp. 79-85 | ||
| 504 | |a Ridell, A., Evertsson, H., Nilsson, S., Sundelöf, L.O., Amphiphilic association of ibuprofen and two nonionic cellulose derivatives in aqueous solution (1999) J. Pharm. Sci., 88, pp. 1175-1181 | ||
| 504 | |a Paulson, M., Edsman, K., Controlled drug release from gels using lipophilic interactions of charged substances with surfactants and polymers (2002) J. Colloid Interface Sci., 248, pp. 194-200 | ||
| 504 | |a Alhaique, F., Carafa, M., Coviello, T., Murtas, E., Riccieri, F.M., Santucci, E., Release from a polysaccharide matrix: Effect of the molecular weight of the drug (1993) Acta Technol. Legis Med., 4, pp. 21-30 | ||
| 504 | |a Möckel, J., (1990) Mechanismus Kontinuierlicher und Gepulster Arzneistoffreisetzung aus Hydrokolloidmatrices, , Ph.D. Thesis, Heinrich-Heine Universität, Düseldorf, Germany | ||
| 504 | |a Bonferoni, M.C., Rossi, S., Tamayo, M., Pedraz, J.L., Domínguez-Gil, A., Caramella, C., On the employement of λ-carrageenan in a matrix system. II. λ-Carrageenan and hydroxypropylmethylcellulose mixtures (1994) J. Control. Release, 30, pp. 175-182 | ||
| 504 | |a Grassi, M., Lapasin, R., Pricl, S., A study of the rheological behavior of scleroglucan weak gel systems (1996) Carbohydrate Polym., 29, pp. 169-181 | ||
| 504 | |a Suggett, A., Water, B., (1975) A Comprehensive Treatise, 4, p. 531. , Franks F. New York: Plenum | ||
| 504 | |a Amsden, B., Solute diffusion within hydrogels. Mechanisms and models (1998) Macromolecules, 31, pp. 8382-8395 | ||
| 504 | |a Ritger, P.L., Peppas, N.A., A simple equation for description of solute release. II. Fickian and anomalous release from swellable devices (1987) J. Control. Release, 5, pp. 37-42 | ||
| 504 | |a Doublier, J.L., Launay, B., Cuvelier, G., Viscoelastic properties of food gels (1992) Viscoelastic Properties of Foods, , M.A. Rao, & J.F. Steffe. Oxford: Elsevier. Ch. 14 | ||
| 504 | |a Frangou, S.A., Morris, E.R., Rees, D.A., Richardson, R.K., Ross-Murphy, S.B., Molecular origin of xhantan solution rheology: Effects of urea on chain conformation and interactions (1982) J. Polym. Sci.: Polym. Lett. Ed., 20, pp. 531-538 | ||
| 504 | |a Ikeda, S., Nishimari, K., 'Weak gel'-type rheological properties of nonaggregated k-carrageenan helices (2001) J. Agric. Food Chem., 49, pp. 4436-4441 | ||
| 504 | |a Harrison, Franks, G.V., Tirtaatmadja, V., Boger, D.V., Suspensions and polymers - Common links in rheology (1999) Korea-Australia Rheol. J., 11, pp. 197-218 | ||
| 504 | |a Stauffer, D., Coniglio, A., Adam, M., Gelation and critical phenomena (1982) Adv. Polym. Sci., 44, pp. 103-158 | ||
| 504 | |a Axelos, M.A.V., Lefebvre, J., Qiu, C.-G., Rao, M.A., Rheology of pectin dispersions and gels (1991) The Chemistry and Technology of Pectin, , R.H. Walter. San Diego, CA: Academic Press. Ch. 11 | ||
| 504 | |a Schramm, G., (1994) A Practical Approach to Rheology and Rheometry, p. 130. , Germany: Gebrueder Haake Gmbh | ||
| 504 | |a Barreiro-Iglesias, R., Alvarez-Lorenzo, C., Concheiro, A., Incorporation of small quantities of surfactants as a way to improve the rheological and diffusional behavior of carbopol gels (2001) J. Control. Release, 77, pp. 59-75 | ||
| 506 | |2 openaire |e Política editorial | ||
| 520 | 3 | |a The structure of scleroglucan gel matrices was characterized by dynamic rheological studies. The results were compared with the release kinetics of theophylline in analogous samples using a Franz diffusion cell, fitting the drug release data with a semi-empirical power law. Dynamic rheology gave information about the viscous and elastic components (loss and storage moduli, respectively) of the gel which could influence the drug-release profiles. Scleroglucan gels showed two structural transitions within the gel regime that coincided with changes in the release pattern. It was found that the introduction of 0.4% (w/w) of theophylline decreased the loss and storage moduli in the 2% (w/w) scleroglucan gels by 50%. The influence of the same wt.% theophylline in other gels was strongly dependent on the gel concentration. These results demonstrated the value of rheological studies to detect matrix structural changes produced by the inclusion of drugs which may modify the drug-release profile. © 2003 Elsevier B.V. All rights reserved. |l eng | |
| 536 | |a Detalles de la financiación: Universidad de Buenos Aires, UBACyT I007 | ||
| 536 | |a Detalles de la financiación: D.L. Bernik is Member of the National Research Council, CONICET. The research was supported by University of Buenos Aires, grant UBACyT I007 and FOMEC. The authors thank Professor Lı́a Gerschenson for useful discussions. | ||
| 593 | |a Lab. de Quim. de Sist. Heterogeneos, Facultad de Ingeniería, Universidad de Buenos Aires, Paseo Colón 850, C1063ACV Buenos Aires, Argentina | ||
| 593 | |a Departamento de Industrias, Fac. de Ciencias Exactas y Naturales, Universidad de Buenos Aires, C1428EHA Buenos Aires, Argentina | ||
| 593 | |a Inst. Quim. Fis. Mat., Ambiente y E., INQUIMAE, Universidad de Buenos Aires, 3er Piso, C1428EHA Buenos Aires, Argentina | ||
| 690 | 1 | 0 | |a DRUG RELEASE |
| 690 | 1 | 0 | |a DYNAMIC RHEOLOGY |
| 690 | 1 | 0 | |a HYDROPHILIC MATRICES |
| 690 | 1 | 0 | |a SCLEROGLUCAN |
| 690 | 1 | 0 | |a ELASTICITY |
| 690 | 1 | 0 | |a GELS |
| 690 | 1 | 0 | |a REACTION KINETICS |
| 690 | 1 | 0 | |a RHEOLOGY |
| 690 | 1 | 0 | |a VISCOSITY |
| 690 | 1 | 0 | |a FRANZ DIFFUSION CELLS |
| 690 | 1 | 0 | |a CONTROLLED DRUG DELIVERY |
| 690 | 1 | 0 | |a SCLEROGLUCAN |
| 690 | 1 | 0 | |a THEOPHYLLINE |
| 690 | 1 | 0 | |a ARTICLE |
| 690 | 1 | 0 | |a DRUG RELEASE |
| 690 | 1 | 0 | |a DRUG STRUCTURE |
| 690 | 1 | 0 | |a ELASTICITY |
| 690 | 1 | 0 | |a FLOW KINETICS |
| 690 | 1 | 0 | |a GEL |
| 690 | 1 | 0 | |a PRIORITY JOURNAL |
| 690 | 1 | 0 | |a VISCOSITY |
| 700 | 1 | |a Rojas, A.M. | |
| 700 | 1 | |a Daraio, Marta Edit | |
| 700 | 1 | |a Bernik, D.L. | |
| 773 | 0 | |d Elsevier, 2003 |g v. 90 |h pp. 355-362 |k n. 3 |p J. Control. Release |x 01683659 |w (AR-BaUEN)CENRE-5509 |t Journal of Controlled Release | |
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| 856 | 4 | 0 | |u https://doi.org/10.1016/S0168-3659(03)00204-9 |y DOI |
| 856 | 4 | 0 | |u https://hdl.handle.net/20.500.12110/paper_01683659_v90_n3_p355_Francois |y Handle |
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| 961 | |a paper_01683659_v90_n3_p355_Francois |b paper |c PE | ||
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| 999 | |c 65854 | ||