Utility of base deficit, lactic acid, microalbuminuria, and C-reactive protein in the early detection of complications in the immediate postoperative evolution

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Objective: To determine the utility of biochemical parameters such as lactic acid (LA), C-reactive protein (CRP), microalbuminuria (MAU), and base deficit (BD) as early markers of complications in the immediate postoperative evolution of elective open gastrointestinal surgeries. Design and Methods:...

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Detalles Bibliográficos
Autor principal: Bianchi, R.A
Otros Autores: Silva, N.A, Natal, M.L, Romero, M.C
Formato: Capítulo de libro
Lenguaje:Inglés
Publicado: 2004
Materias:
ARGENTINA
Acceso en línea:Registro en Scopus
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Registro en la Biblioteca Digital
Aporte de:Registro referencial: Solicitar el recurso aquí
Biblioteca Central Dr. Luis F. Leloir (FCEN) de Universidad de Buenos Aires
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024 7 |2 scopus  |a 2-s2.0-1842839963 
024 7 |2 cas  |a C reactive protein, 9007-41-4; lactic acid, 113-21-3, 50-21-5; Biological Markers; C-Reactive Protein, 9007-41-4; Creatinine, 60-27-5; Lactic Acid, 50-21-5 
040 |a Scopus  |b spa  |c AR-BaUEN  |d AR-BaUEN 
030 |a CLBIA 
100 1 |a Bianchi, R.A. 
245 1 0 |a Utility of base deficit, lactic acid, microalbuminuria, and C-reactive protein in the early detection of complications in the immediate postoperative evolution 
260 |c 2004 
270 1 0 |m Romero, M.C.; Lab. de Analisis Biologicos, Depto. de Quím. Biol., Cd. Autónoma de Buenos Aires, Buenos Aires, Argentina; email: cris@qb.fcen.uba.ar 
506 |2 openaire  |e Política editorial 
504 |a American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference: Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis (1992) Crit. Care Med., 20, pp. 864-874 
504 |a Bone, R.C., Toward a theory regarding the pathogenesis of systemic inflammatory response syndrome: What we do and do not know about cytokine regulation (1996) Crit. Care Med., 24, pp. 163-172 
504 |a Moore, F.A., Moore, E.E., Evolving concepts in the pathogenesis of postinjury multiple organ failure (1995) Surg. Clin. North Am., 75, pp. 257-277 
504 |a Ogawa, M., Mechanisms of the development of organ failure following surgical insult: The "second attack" theory (1996) Cin. Intensive Care, 7, pp. 34-38 
504 |a Clavien, P., Sanabria, J.R., Strasberg, S., Proposed classification of complications of surgery with examples of utility in cholescystectomy (1992) Surgery, 3, pp. 5l8-526 
504 |a Haga, Y., Beffu, T., Doi, K., Nogawa, F., Mugita, N., Ikei, S., Systemic inflammatory response syndrome and organ dysfunction following gastrointestinal surgery (1997) Crit. Care Med., 25, pp. 994-2000 
504 |a Roumen, R.M., Dedl, H., Schlog, G., Scoring systems and blood lactate concentrations in relation to the development of adult respiratory distress syndrome and multiple organ failure in severely traumatised patients (1993) J. Trauma, 35, pp. 349-355 
504 |a Abramson, D., Scalea, T.M., Hitchcock, R., Lactate clearance and survival following injury (1993) J. Trauma, 35, pp. 584-588 
504 |a Farah, H., Matthew, J.M., Philip, S.M., Scott, R.S., Elliott, D.C., Serum lactate and base deficit as predictors of mortality and morbidity (2003) Am. J. Surg., 185, pp. 485-491 
504 |a Runhart, K., Boyer, O., Brunkhorst, F., Meisner, M., Markers of endothelial damage in organ dysfunction and sepsis (2002) Crit. Care Med., 30, pp. 5302-5312 
504 |a Hocke, E., Sacha, Z., The endothelium in sepsis: Source of and target of inflammation (2001) Crit. Care Med., 29, pp. 521-527 
504 |a Zkria, B.A., Boscom, J.U., (1994) Mechanisms of Multiple System Organ Failure: Reperfusion Injuries and Capillary Leak Syndrome, pp. 443-492. , New York: Future Publishing 
504 |a Gosling, P., Sanghera, K., Dickson, G., Generalised vascular permeability and pulmonary function in patients following serious trauma (1994) J. Trauma, 36, pp. 1-5 
504 |a Ballou, S.P., Kushner, J., C-reactive protein and the acute phase response (1992) Adv. Intern. Méd., 37, pp. 313-336 
520 3 |a Objective: To determine the utility of biochemical parameters such as lactic acid (LA), C-reactive protein (CRP), microalbuminuria (MAU), and base deficit (BD) as early markers of complications in the immediate postoperative evolution of elective open gastrointestinal surgeries. Design and Methods: Sixty-two patients subject to elective open gastrointestinal surgery were evaluated during a period of 22 months. Results: From the initial 62 patients, 2 were excluded, 29 (48.3%) evolved without complications, and 31 (51.6%) with complications. It was observed that the most significant areas under the ROC curve corresponded to BD in the preoperative period, LA on the first day, and CRP from the second to the seventh day after surgery. MAU was not a discriminating parameter since it did not reach a significant area under the curve (AUC) at any time. Conclusions: The biochemical markers that best relate to the presence of complications are BD in the preoperative period, LA on the first day, and CRP from the second to the seventh day after surgery. © 2004 The Canadian Society of Clinical Chemists. All rights reserved.  |l eng 
593 |a Servicio de Cirugía General, Hosp. Gen. Agudos Dr. Cosme Argerich, Gobierno Cd. Auton. de Buenos Aires, Argentina 
593 |a Laboratorio Central, Hosp. Gen. Agudos Dr. Cosme Argerich, Gobierno Cd. Auton. de Buenos Aires, Argentina 
593 |a Departamento de Matemática, Fac. de Ciencias Exactas Y Naturales, Universidad de Mar del Plara, Provincia de Buenos Aires, Argentina 
593 |a Lab. de Analisis Biologicos, Depto. de Quím. Biól., Cd. Autónoma de Buenos Aires, Argentina 
593 |a Lab. de Analisis Biologicos, Depto. de Quím. Biol., Cd. Autónoma de Buenos Aires, Buenos Aires, Argentina 
690 1 0 |a BIOCHEMICAL MARKERS 
690 1 0 |a POSTOPERATIVE EVOLUTION 
690 1 0 |a C REACTIVE PROTEIN 
690 1 0 |a LACTIC ACID 
690 1 0 |a ADULT 
690 1 0 |a AGED 
690 1 0 |a ARTICLE 
690 1 0 |a CHEMICAL PARAMETERS 
690 1 0 |a CONTROLLED STUDY 
690 1 0 |a EARLY DIAGNOSIS 
690 1 0 |a FEMALE 
690 1 0 |a GASTROINTESTINAL SURGERY 
690 1 0 |a HUMAN 
690 1 0 |a MAJOR CLINICAL STUDY 
690 1 0 |a MALE 
690 1 0 |a MICROALBUMINURIA 
690 1 0 |a POSTOPERATIVE COMPLICATION 
690 1 0 |a PREOPERATIVE EVALUATION 
690 1 0 |a PRIORITY JOURNAL 
690 1 0 |a STATISTICAL SIGNIFICANCE 
690 1 0 |a ACID-BASE IMBALANCE 
690 1 0 |a ADULT 
690 1 0 |a AGED 
690 1 0 |a ALBUMINURIA 
690 1 0 |a BIOLOGICAL MARKERS 
690 1 0 |a C-REACTIVE PROTEIN 
690 1 0 |a CREATININE 
690 1 0 |a DIGESTIVE SYSTEM SURGICAL PROCEDURES 
690 1 0 |a FEMALE 
690 1 0 |a HUMANS 
690 1 0 |a LACTIC ACID 
690 1 0 |a MALE 
690 1 0 |a MIDDLE AGED 
690 1 0 |a POSTOPERATIVE COMPLICATIONS 
690 1 0 |a POSTOPERATIVE PERIOD 
690 1 0 |a PREDICTIVE VALUE OF TESTS 
690 1 0 |a PROSPECTIVE STUDIES 
690 1 0 |a SYSTEMIC INFLAMMATORY RESPONSE SYNDROME 
651 4 |a ARGENTINA 
700 1 |a Silva, N.A. 
700 1 |a Natal, M.L. 
700 1 |a Romero, M.C. 
773 0 |d 2004  |g v. 37  |h pp. 404-407  |k n. 5  |p Clin. Biochem.  |x 00099120  |w (AR-BaUEN)CENRE-4213  |t Clinical Biochemistry 
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856 4 0 |u https://doi.org/10.1016/j.clinbiochem.2003.12.011  |y DOI 
856 4 0 |u https://hdl.handle.net/20.500.12110/paper_00099120_v37_n5_p404_Bianchi  |y Handle 
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