Glutathione depletion and anaesthesia in mice alter heme and drug metabolising enzymes
The effects of enflurane and isoflurane on heme metabolism, its regulation, and on some parameters involved in the hepatic drug metabolising system in animals under GSH depletion were investigated. A single dose of the anaesthethics (1 ml kg-1, i.p.) was administered to control and GSH depleted mice...
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| Formato: | Capítulo de libro |
| Lenguaje: | Inglés |
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2005
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| Acceso en línea: | Registro en Scopus DOI Handle Registro en la Biblioteca Digital |
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| LEADER | 11784caa a22012497a 4500 | ||
|---|---|---|---|
| 001 | PAPER-4115 | ||
| 003 | AR-BaUEN | ||
| 005 | 20230518203337.0 | ||
| 008 | 190411s2005 xx ||||fo|||| 00| 0 eng|d | ||
| 024 | 7 | |2 scopus |a 2-s2.0-19744373984 | |
| 024 | 7 | |2 cas |a 5 aminolevulinate synthase, 9037-14-3; enflurane, 13838-16-9; glutathione, 70-18-8; heme, 14875-96-8; isoflurane, 26675-46-7; 5-Aminolevulinate Synthetase, EC 2.3.1.37; Acetaminophen, 103-90-2; Enflurane, 13838-16-9; Glutathione Transferase, EC 2.5.1.18; Glutathione, 70-18-8; Heme, 14875-96-8; Isoflurane, 26675-46-7; Pharmaceutical Preparations | |
| 040 | |a Scopus |b spa |c AR-BaUEN |d AR-BaUEN | ||
| 030 | |a BBGSB | ||
| 100 | 1 | |a Buzaleh, A.M. | |
| 245 | 1 | 0 | |a Glutathione depletion and anaesthesia in mice alter heme and drug metabolising enzymes |
| 260 | |c 2005 | ||
| 270 | 1 | 0 | |m Batlle, A.M.D.C.Viamonte 1881 10 A, C1056ABA- Buenos Aires, Argentina; email: batlle@mail.retina.ar |
| 506 | |2 openaire |e Política editorial | ||
| 504 | |a Batlle, A.M., Del, C., Porphyrins, porphyrias, cancer and photodynamic therapy-a model for carcinogenesis (1993) J. Photochem. Photobiol., B Biol., 20, pp. 5-22 | ||
| 504 | |a Jensen, N.F., Fiddler, D.S., Striepe, V., Anesthetic considerations in porphyrias (1995) Anesth. Analg., 80, pp. 591-599 | ||
| 504 | |a Quail, A.M., Modern inhalational anaesthetic agents. A review of halothane, isoflurane and enflurane (1989) Med. J. Aust., 150, pp. 95-102 | ||
| 504 | |a Buzaleh, A.M., Vazquez, E., Enríquez De Salamanca, R., Batlle A.m.del, C., An overview of anaesthesia and porphyria (Review) (1997) Endocrinol. Metab., 4, pp. 267-279 | ||
| 504 | |a Buzaleh, A.M., Batlle, A.M.D.C., Administration of volatile anaesthetics to animals treated with cobalt as inductor of heme oxygenase (2000) Pharmacol. Rev. Commun., 11, pp. 39-47 | ||
| 504 | |a Lores Arnaiz, S., Llesuy, S., Cutrin, J.C., Boveris, A., Oxidative stress by acute acetaminophen administration in mouse liver (1995) Free Radic. Biol. Med., 19, pp. 303-310 | ||
| 504 | |a Vazquez, E., Buzaleh, A.M., Wider, E., Batlle, A., Reduced thiosulphate affinity for erythrocyte rhodanese: An explanation for increased δ-Aminolevulinic synthetase activity in some porphyrias? (1986) IRCS Med. Sci., 14, pp. 999-1000 | ||
| 504 | |a Lieber, C.B., Cytochrome P-4502E1: Its physiological and pathological role (1997) Physiol. Rev., 77, pp. 517-544 | ||
| 504 | |a Marver, H., Tschudy, D., Perlroth, M., Collins, A., δ-Aminolevulinic acid synthetase I. Studies in liver homogenates (1966) J. Biol. Chem., 241, pp. 2803-2809 | ||
| 504 | |a Batlle, A., Wider De Xifra, E., Stella, A.M., A simple method for measuring erythrocyte porphobilinogenase and its use in the diagnosis of acute intermittent porphyria (1978) Int. J. Biochem., 9, pp. 871-875 | ||
| 504 | |a Tenhunen, R., Marver, H.S., Schmid, R., The enzymatic catabolism of hemoglobin: Stimulation of microsomal heme oxygenase by hemin (1970) J. Lab. Clin. Med., 75, pp. 410-421 | ||
| 504 | |a Sörbo, B.H., Crystalline rhodanese I. Purification and physico-chemical examination (1953) Acta Chem. Scand., 7, pp. 1129-1136 | ||
| 504 | |a Reinke, L.A., Moyer, M.J., A microsomal oxidation which is highly inducible by ethanol (1985) Drug Metab. Dispos., 13, pp. 548-552 | ||
| 504 | |a Knox, W.E., L-Tryptophan 2,3-dioxygenase (tryptophan pyrrolase) (rat liver) (1970) Methods Enzymol., 17, pp. 415-417 | ||
| 504 | |a Habig, W.H., Pabst, M.J., Jakoby, W.B., Glutation S-transferases (1974) J. Biol. Chem., 249, pp. 7130-7139 | ||
| 504 | |a Omura, T., Sato, R., The carbon monoxide-binding pigment of liver microsomes (1964) J. Biol. Chem., 239, pp. 2370-2378 | ||
| 504 | |a Rossi, R., Cardaioli, E., Scaloni, A., Amiconi, G., Di Simplicio, P., Thiol groups in proteins as endogenous reductans to determine glutathione protein mixed disulphides in biological systems (1995) Biochim. Biophys. Acta, 1243, pp. 230-238 | ||
| 504 | |a Lowry, O., Rosebrough, N., Farr, A., Randall, R., Protein measurement with the Folin-phenol reagent (1951) J. Biol. Chem., 193, pp. 265-275 | ||
| 504 | |a Dale, O., Nilsen, O.G., Glutathione and glutathione S-transferases in rat liver after inhalation of halothane and enflurane (1984) Toxicol. Lett., 23, pp. 61-66 | ||
| 504 | |a Agar, N.S., Lewis, G.B., Effect of halothane and enflurane anaesthesia on the level of reduced glutathione in human red blood cells (1980) Anaesth. Intensive Care, 8, pp. 356-358 | ||
| 504 | |a Makin, A.J., Wendon, J., Williams, R., A 7-year experience of severe acetaminophen-induced hepatotoxicity (1987-1993) (1995) Gastroenterology, 6, pp. 1907-1916 | ||
| 504 | |a Kozer, E., Evans, S., Barr, J., Greenberg, R., Soriano, I., Bulkowstein, M., Petrov, I., Berkovitch, M., Glutathione, glutathione-dependent enzymes and antioxidant status in erythrocytes from children treated with high-dose paracetamol (2003) Br. J. Clin. Pharmacol., 55, pp. 234-240 | ||
| 504 | |a Amimoto, T., Matsura, T., Koyama, S., Nakanishi, T., Yamada, K., Kajiyama, G., Acetaminophen-induced hepatic injury in mice: The role of lipid peroxidation and effects of pretreatment with coenzyme Q10 and alpha-tocopherol (1995) Free Radic. Biol. Med., 19, pp. 169-176 | ||
| 504 | |a Tarloff, J.B., Khairallah, E.A., Cohen, S.D., Goldstein, R.S., Sex- and age-dependent acetaminophen hepato- and nephrotoxicity in Sprague-Dawley rats: Role of tissue accumulation, non protein sulfhydryl depletion, and covalent binding (1996) Fundam. Appl. Toxicol., 30, pp. 13-22 | ||
| 504 | |a Dahlin, D.C., Miwa, G.T., Lu, A.Y.H., Nelson, S.D., N-acetyl-p-benzoquinone imine: A cytochrome P-450 mediated oxidation product of acetaminophen (1984) Proc. Natl. Acad. Sci. U. S. A., 81, pp. 1327-1331 | ||
| 504 | |a Yonamine, M., Aniya, Y., Yokomakura, T., Koyama, T., Nagamine, T., Nakanishi, H., Acetaminophen-derived activation of liver microsomal glutathione S-transferase of rats (1996) Jpn. J. Pharmacol., 72, pp. 175-181 | ||
| 504 | |a Yoshida, T., Oguro, T., Numazawa, S., Kuroiwa, Y., Effects of phorone (diisopropylidene acetone), a glutathione (GSH) depletor, on hepatic enzymes involved in drug and heme metabolism in rats: Evidence that phorone is a potent inducer of heme oxygenase (1987) Biochem. Biophys. Res. Commun., 145, pp. 502-508 | ||
| 504 | |a Kaliman, P.A., Barannik, T.V., Regulation of δ-aminolevulinate synthase activity during the development of oxidative stress (1999) Biochemistry (Mosc.), 64, pp. 699-704 | ||
| 504 | |a Buzaleh, A.M., Afonso, S.G., Del Batlle, C.A.M., Anestésicos volátiles y estrés oxidativo (2002) Medicina, 62, p. 423 | ||
| 504 | |a Oguro, T., Yoshida, T., Numazawa, S., Kuroiwa, Y., Possible role of glutathione depletion in the induction of rate-limiting enzymes involved in heme degradation and polyamine biosynthesis in the liver of rats (1990) J. Pharmacobio-dyn., 13, pp. 628-636 | ||
| 504 | |a Saunders, E.L., Maines, M.D., Meredith, M.J., Freeman, M.L., Enhancement of heme oxygenase-1 synthesis by glutathione depletion in Chinese hamster ovary cells (1991) Arch. Biochem. Biophys., 288, pp. 368-373 | ||
| 504 | |a Fulton, B., Jeffery, E.H., The temporal relationship between hepatic GSH loss, heme oxygenase induction, and cytochrome P450 loss following intraperitoneal aluminum administration to mice (1994) Toxicol. Appl. Pharmacol., 127, pp. 291-297 | ||
| 504 | |a Llesuy, S.F., Tomaro, M.L., Heme oxygenase and oxidative stress. Evidence of involvement of bilirubin as physiological protector against oxidative damage (1994) Biochim. Biophys. Acta, 1223, pp. 9-14 | ||
| 504 | |a Hanna, A.N., Mcdonald Jr., J.S., Miller, C.H., Couri, D., Pretreatment with paracetamol inhibits metabolism of enflurane in rats (1989) Br. J. Anaesth., 62, pp. 429-433 | ||
| 504 | |a Uhlig, S., Wendel, A., The physiological consequences of glutathione variations (1992) Life Sci., 51, pp. 1083-1094 | ||
| 520 | 3 | |a The effects of enflurane and isoflurane on heme metabolism, its regulation, and on some parameters involved in the hepatic drug metabolising system in animals under GSH depletion were investigated. A single dose of the anaesthethics (1 ml kg-1, i.p.) was administered to control and GSH depleted mice, animals were sacrificed 20 min after. As a consequence of GSH depletion, a significant inhibition in δ-Aminolevulinic acid synthetase activity, the first enzyme of heme bioxynthesis, and a striking induction in Heme oxygenase activity, the main enzyme of heme metabolism, were observed. Cytochrome P-450 levels and the activities of P-4502E1 and glutathione S-transferase were increased. These changes in heme metabolism and drug metabolising enzyme system were not altered further by the administration of enflurane or isoflurane. These findings would indicate that the status of oxidative stress produced by GSH depletion could not be affected by these anaesthetics and/or that disturbances in heme metabolism were already too important to undergo further variations. © 2005 Elsevier B.V. All rights reserved. |l eng | |
| 536 | |a Detalles de la financiación: Consejo Nacional de Investigaciones Científicas y Técnicas | ||
| 536 | |a Detalles de la financiación: A.M. Buzaleh and A. Batlle hold the post of Associated and Superior Scientific Researchers at the Argentine National Research Council (CONICET). This work has been supported by grants from the CONICET, the Scientific and Technologic Agency and the University of Buenos Aires, Argentine. | ||
| 593 | |a Centro de Investigaciones Sobre Porfirinas Y Porfirias (CIPYP)- (CONICET- FCEN, UBA), Ciudad Universitaria, Pabellón II, Buenos Aires, Argentina | ||
| 593 | |a Viamonte 1881 10 A, C1056ABA- Buenos Aires, Argentina | ||
| 690 | 1 | 0 | |a DRUG METABOLISING ENZYME SYSTEM |
| 690 | 1 | 0 | |a ENFLURANE |
| 690 | 1 | 0 | |a GSH |
| 690 | 1 | 0 | |a HEME METABOLISM |
| 690 | 1 | 0 | |a ISOFLURANE |
| 690 | 1 | 0 | |a 5 AMINOLEVULINATE SYNTHASE |
| 690 | 1 | 0 | |a DRUG METABOLIZING ENZYME |
| 690 | 1 | 0 | |a ENFLURANE |
| 690 | 1 | 0 | |a GLUTATHIONE |
| 690 | 1 | 0 | |a HEME |
| 690 | 1 | 0 | |a ISOFLURANE |
| 690 | 1 | 0 | |a ANESTHESIA |
| 690 | 1 | 0 | |a ANIMAL EXPERIMENT |
| 690 | 1 | 0 | |a ANIMAL MODEL |
| 690 | 1 | 0 | |a ANIMAL TISSUE |
| 690 | 1 | 0 | |a ARTICLE |
| 690 | 1 | 0 | |a CONTROLLED STUDY |
| 690 | 1 | 0 | |a DRUG METABOLISM |
| 690 | 1 | 0 | |a HEME SYNTHESIS |
| 690 | 1 | 0 | |a LIVER METABOLISM |
| 690 | 1 | 0 | |a MALE |
| 690 | 1 | 0 | |a METABOLIC DISORDER |
| 690 | 1 | 0 | |a MOUSE |
| 690 | 1 | 0 | |a NONHUMAN |
| 690 | 1 | 0 | |a PRIORITY JOURNAL |
| 690 | 1 | 0 | |a REGULATORY MECHANISM |
| 690 | 1 | 0 | |a 5-AMINOLEVULINATE SYNTHETASE |
| 690 | 1 | 0 | |a ACETAMINOPHEN |
| 690 | 1 | 0 | |a ANESTHESIA, INHALATION |
| 690 | 1 | 0 | |a ANIMALS |
| 690 | 1 | 0 | |a ENFLURANE |
| 690 | 1 | 0 | |a GLUTATHIONE |
| 690 | 1 | 0 | |a GLUTATHIONE TRANSFERASE |
| 690 | 1 | 0 | |a HEME |
| 690 | 1 | 0 | |a ISOFLURANE |
| 690 | 1 | 0 | |a MALE |
| 690 | 1 | 0 | |a MICE |
| 690 | 1 | 0 | |a PHARMACEUTICAL PREPARATIONS |
| 690 | 1 | 0 | |a ANIMALIA |
| 700 | 1 | |a Batlle, A.M.D.C. | |
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