A simple prediction rule for significant renal artery stenosis in patients undergoing cardiac catheterization
Background: Renal artery stenosis (RAS) is a potentially reversible cause of hypertension and renal insufficiency and is associated with poor prognosis. Methods: We aimed to identify simple predictors of significant RAS among patients undergoing coronary angiography. Prospective data were collected...
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2005
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| 100 | 1 | |a Cohen, M.G. | |
| 245 | 1 | 2 | |a A simple prediction rule for significant renal artery stenosis in patients undergoing cardiac catheterization |
| 260 | |c 2005 | ||
| 270 | 1 | 0 | |m Cohen, M.G.; Division of Cardiology, University of North Carolina at Chapel Hill, Bioinformatics Building, 130 Mason Farm Road, CB # 7075, Chapel Hill, NC 27599-7075, United States; email: mgcohen@med.unc.edu |
| 506 | |2 openaire |e Política editorial | ||
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| 520 | 3 | |a Background: Renal artery stenosis (RAS) is a potentially reversible cause of hypertension and renal insufficiency and is associated with poor prognosis. Methods: We aimed to identify simple predictors of significant RAS among patients undergoing coronary angiography. Prospective data were collected on 843 consecutive patients who underwent cardiac catheterization and abdominal aortography. Stenoses ≥75% were considered significant. Multivariable logistic regression was used to assess the relationship between baseline characteristics and coronary anatomy with significant RAS. A simple risk score was derived from the model. Results: The prevalence of RAS ≥75% was 11.7%. Independent predictors of significant RAS were older age, higher creatinine levels, peripheral vascular disease, number of cardiovascular drugs, hypertension, female sex, and 3-vessel coronary artery disease or previous coronary artery bypass graft. The concordance index of the model was 0.802. These variables were used to develop a simple predictive score of significant RAS for patients undergoing cardiac catheterization. The prevalence of RAS increased stepwise with increasing score values: 0.6% for a score ≤5, 1.5% for 6 to 7, 6.1% for 8 to 9, 12.2% for 10 to 11, 18.7% for 12 to 14, 35.7% for 15 to 17, and 62.1% for ≥18 (P < .001). Approximately one third of the patients had a score ≥11, which yielded a sensitivity of 76% and a specificity of 71%. Conclusions: Renal artery stenosis is a relatively common finding among patients referred for coronary angiography. A simple score can predict the presence of significant RAS among patients referred for cardiac catheterization. © 2005, Mosby, Inc. All rights reserved. |l eng | |
| 593 | |a Division of Cardiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States | ||
| 593 | |a Servicio de Hemodinamia Y Cardiología Intervencionista, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina | ||
| 593 | |a Facultad de Ciencias Exactas Y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina | ||
| 593 | |a Division of Cardiology, University of North Carolina at Chapel Hill, Bioinformatics Building, 130 Mason Farm Road, CB # 7075, Chapel Hill, NC 27599-7075, United States | ||
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