Galactofuranose-containing glycoconjugates in trypanosomatids

Galactofuranose has been characterized in glycoinositolphospholipid (GIPL) anchor-like structures having a glycerolipid or a ceramide, as in lipopeptidophosphoglycan (LPPG) of Trypanosoma cruzi, in the oligosaccharide core of lipophosphoglycan (LPG) of Leishmania species, and also modifying high-man...

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Autor principal: De Lederkremer, R.M
Otros Autores: Colli, W.
Formato: Capítulo de libro
Lenguaje:Inglés
Publicado: 1995
Acceso en línea:Registro en Scopus
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024 7 |2 scopus  |a 2-s2.0-0028789599 
024 7 |2 cas  |a Antibodies, Protozoan; Antigens, Protozoan; Galactose, 26566-61-0; Glycoconjugates; Glycoproteins; Immune Sera; Polysaccharides 
040 |a Scopus  |b spa  |c AR-BaUEN  |d AR-BaUEN 
100 1 |a De Lederkremer, R.M. 
245 1 0 |a Galactofuranose-containing glycoconjugates in trypanosomatids 
260 |c 1995 
506 |2 openaire  |e Política editorial 
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504 |a Lederkremer, J.L.M., Alves, J.-M., Fonseca, G.C., Colli, W., A lipo- peptidophosphoglycan from Trypanosoma cruzi (Epimastigota). Isolation, purification and carbohydrate composition (1976) Biochim. Biophys. Acta, 444, pp. 85-96 
504 |a Lederkremer, R.M., Casal, O.L., Tanaka, C.T., Colli, W., Ceramide and inositol content of the lipopeptidophosphoglycan from (1978) Trypanosoma Cruzi. Biochem. Biophys. Res. Common., 85, pp. 1268-1274 
504 |a Lederkremer, J.M., Casal, O.-L., Alves, J.M., Colli, W., Evidence for the presence of D-galactofuranose in the lipopeptidophosphoglycan from (1980) Trypanosoma Cruzi. FEBS Lett., 116, pp. 25-29 
504 |a Lederkremer, R.M., Casal, O.L., Alves, M.J.M., Colli, W., Trypanosoma cruzi (1985) Biochem. Int, 10, pp. 89-96 
504 |a Lederkremer, R.M., Casal, O.L., Couto, A., Colli, W., Structural studies on the oligosaccharide moiety of the lipopeptidopbosphoglycan from (1985) Trypanosoma Cruzi. Eur. J. Biochem., 151, pp. 539-542 
504 |a Lederkremer, R.M., Lima, C., Ramirez, M.I., Casal, O.L., Structural features of the lipopeptidophosphoglycan from Trypanosoma cruzi common with the glycophosphatidylinositol anchors (1990) Eur. J. Biochem., 192, pp. 337-345 
504 |a Lederkremer, R.M., Lima, C., Ramirez, M.I., Ferguson, M.A.J., Homans, S.W., Thomas-Oates, J., Complete structure of the glycan of lipopeptidophosphoglycan from Trypanosoma cruzi epimastigotes (1991) J. Biol. Chem., 266, pp. 23670-23675 
504 |a Lederkremer, R.M., Lima, C.E., Ramirez, M.I., Gonsalves, M.F., Colli, W., Hexadecylpalmitoylglycerol or ceramide is linked to similar glycophosphoinositol anchor-like structures in (1993) Trypanosoma Cruzi. Eur. J. Biochem., 218, pp. 929-936 
504 |a Lederkremer, R.M., Nahmad, V.B., Varela, O., Synthesis of a-D- galactofuranosyl phosphate (1994) J. Org. Chem., 59, pp. 690-692 
504 |a Lee, W.L., Lloyd, K.O., Further studies on the peptido-galactomannan from the yeast form of (1975) Cladosporium Wemeckii. Arch. Biochem. Biophys., 171, pp. 613-623 
504 |a Mc Conville, J.J., Ferguson, M.A.J., The structure, biosynthesis and function of glycosylated phosphatidylinositols in the parasitic protozoa and higher eukaryotes (1993) Biochem. J., 294, pp. 305-324 
504 |a Mc Conville, M.J., Homans, S.W., Thomas-Oates, J.E., Del, I.A., Bacic, A., Structures of the glycoinositolphospholipids from (1989) Leishmania Major. J. Biol Chem., 265, pp. 7385-7394 
504 |a Mc Conville, M.J., Collidge, T.A.C., Ferguson, L.A.J., Schneider, P., The glycoinositolphospholipids of Leishmania mexicana promastigotes (1993) J. Biol. Chem., 268, pp. 15595-15604 
504 |a Mc Neil, M., Wallner, S.J., Hunter, S.W., Brennan, P.J., Demonstration that the galactosyl and arabinosyl residues in the cell wall arabinogalactan of Mycobacterium leprae and Mycobacterium tuberculosis are furanoid (1987) Carbohydr. Res., 166, pp. 299-308 
504 |a Mendelzon, D.H., Parodi, A.J., N-Linked high mannose-type oligosaccharides in the protozoa Crithidia fasciculata and Crithidia harmosa contain galactofuranose residues (1986) J. Biol. Chem., 261, pp. 2129-2133 
504 |a Mendorhja-Previato, L., Gorin, P.A.J., Travassos, L.R., Galactose- containing polysaccharides from the human pathogens Sporothrix schenckii and (1980) Ceratocystis Stenoceras. Infect. Immun., 29, pp. 934-939 
504 |a Mendona-Previato, L., Gorin, P.A.J., Braga, A.F., Scharfstein, J., Previato, J.O., Chemical structure and antigenic aspects of complexes obtained from epimastigotes of (1983) Trypanosoma Cruzi. Biochemistry, 22, pp. 4980-4987 
504 |a Moraes, C.T., Bosch, M., Parodi, A.J., Structural characterization of several galactofuranose-containing, high-mannose-type oligosaccharides present in glycoproteins of the trypanosomatid (1988) Leptomonas Samueli. Biochemistry, 27, pp. 1543-1549 
504 |a Notermans, S., Veeneman, G.H., Van Zuylen, C., Hoogerhout, W.E.M., Van Boom, J.H., (L-5)-Linked [J-D-galactofuranosides are immunodominant in extracellular polysaccharides of Penicillium and Aspergillus species (1988) Mol. Immunol., 25, pp. 975-979 
504 |a Previato, J.O., Gorin, P.A., Mazurek, J.L., Xavier, M.T., Foumet, B., Wieruszesk, J.M., Mendoraja-Previalo, L., Primary structure of the oligosaccharide chain of lipopeptidophosphoglycan of epimastigote forms of (1990) Trypanosoma Cruzi. J. Biol Chem., 265, pp. 2518-2526 
504 |a Previato, J.O., Mendona Previato, L., Jones, C., Wait, R., Foumet, B., Structural characterization of a novel class of glycophosphobpids from the protozoan (1992) Leptomonas Samueli. J. Biol. Chem., 267, pp. 24279-24286 
504 |a Previato, J.O., Mendonfa-Previato, L., Jones, C., Wait, R., Structure of the carbohydrate moiety of the glycophosphosphingolipid of (1993) Endotrypanum Schaudinni. Glycoconjugate J., 10, p. 340 
504 |a Richards, J., Perry, M.B., Carlo, D.T., The specific capsular polysaccharide of Streptococcus pneumoniae type 23 F (1983) Can. J. Biochem. Cell. Biol, 61, pp. 178-190 
504 |a Ryan, K.A., Garraway, L.A., Descoteaux, A., Tbrco, S.J., Beverley, S., Isolation of virulence genes directing surface glycosylphosphatidylinositol synthesis by functional complementation of (1993) Leishmania. Proc. Natl Acad Sci. USA, 90, pp. 8609-8613 
504 |a Steck, T.L., Dawson, G., Topographical distribution of complex carbohydrates in the erythrocyte membrane (1974) J. Biol Chem., 249, pp. 2135-2142 
504 |a Turco, S.J., Descoteaux, A., The lipophosphoglycan of Leishmania parasites (1992) Annu. Rev. Microbiol., 46, pp. 65-94 
504 |a Unkcfer, C.J., Gander, J., The 5-O-D-galactofuranosyl-containing peptidophosphogalactomannan of (1990) Penicillium Charlesii. J. Biol Chem., 265, pp. 685-689 
504 |a Wallace, F.G., The trypanosomatids of insects and arachnids (1966) Exp.Parasitol., 18, pp. 124-193 
504 |a Zingales-Martin, N.F., Lederkremer, R.M., Colli, W., Endogenous and surface labeling of glycoconjugates from the three differentiation stages of (1982) Trypanosoma Cruzi. FEBS Lett., 142, pp. 238-242 
520 3 |a Galactofuranose has been characterized in glycoinositolphospholipid (GIPL) anchor-like structures having a glycerolipid or a ceramide, as in lipopeptidophosphoglycan (LPPG) of Trypanosoma cruzi, in the oligosaccharide core of lipophosphoglycan (LPG) of Leishmania species, and also modifying high-mannose chains of trypanosomatid glycoproteins. Galactofuranose is usually present linked β1→3 to Man, either as a terminal non-reducing unit, like in LPPG, or in the middle of the oligosaccharide core, as in LPG. The presence in protozoan parasites of galactose in the furanose configuration is a feature which deserves further attention since the mammalian hosts donot appear to produce glycoconjugates containing this structural unit. For that reason, hosts produceantibodies against galactofuranose, which may turn out to be important in understanding the pathogenesis and in the development of diagnostic methods. The metabolic pathways involved in the attachment to or removal of galactofuranose from glycoconjugates have not yet been elucidated. This is an area ofincipient research, but of growing importance, since it will foster the design of inhibitors which may prove to be useful for the treatment of disease. © 1995 Oxford University Press.  |l eng 
593 |a Departamento de Química Orgánica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires and Ciudad Universitaria, Pabellón 2, Buenos Aires, Argentina 
593 |a Departamento de Química Orgánica, Instituto de Química, Universidade de Sāo Paulo, C.P. 20780, Sāo Paulo, 01498-970, Brazil 
690 1 0 |a GANGLIOSIDES 
690 1 0 |a HPTLC-IMMUNOSTAINING 
690 1 0 |a PLATELETS 
690 1 0 |a SELECTIN LIGANDS 
690 1 0 |a SLEX 
690 1 0 |a GLYCOCONJUGATE 
690 1 0 |a GLYCOPROTEIN 
690 1 0 |a LIPOPEPTIDE 
690 1 0 |a CARBOHYDRATE ANALYSIS 
690 1 0 |a CHEMICAL STRUCTURE 
690 1 0 |a LEISHMANIA 
690 1 0 |a PRIORITY JOURNAL 
690 1 0 |a REVIEW 
690 1 0 |a TRYPANOSOMA CRUZI 
690 1 0 |a ANIMAL 
690 1 0 |a ANTIBODIES, PROTOZOAN 
690 1 0 |a ANTIGENS, PROTOZOAN 
690 1 0 |a CARBOHYDRATE SEQUENCE 
690 1 0 |a GALACTOSE 
690 1 0 |a GLYCOCONJUGATES 
690 1 0 |a GLYCOPROTEINS 
690 1 0 |a IMMUNE SERA 
690 1 0 |a MOLECULAR SEQUENCE DATA 
690 1 0 |a POLYSACCHARIDES 
690 1 0 |a SUPPORT, NON-U.S. GOV'T 
690 1 0 |a TRYPANOSOMATINA 
700 1 |a Colli, W. 
773 0 |d 1995  |g v. 5  |h pp. 547-552  |k n. 6  |p Glycobiology  |x 09596658  |t Glycobiology 
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