Immunomodulatory activities of Cedrela lilloi and Trichilia elegans aqueous leaf extracts

The effects of Cedrela lilloi and Trichilia elegans (Meliaceae) aqueous leaf extracts on several parameters of the mouse immune system were studied. Both extracts showed a strong anticomplementary activity and inhibited the phagocytosis of opsonized sheep erythrocytes and the activation of the oxida...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autor principal: Nores, M.M
Otros Autores: Courrèges, M.C, Benencia, F., Coulombié, F.C
Formato: Capítulo de libro
Lenguaje:Inglés
Publicado: 1997
Materias:
Acceso en línea:Registro en Scopus
DOI
Handle
Registro en la Biblioteca Digital
Aporte de:Registro referencial: Solicitar el recurso aquí
LEADER 09009caa a22012377a 4500
001 PAPER-3353
003 AR-BaUEN
005 20230518203249.0
008 190411s1997 xx ||||fo|||| 00| 0 eng|d
024 7 |2 scopus  |a 2-s2.0-0343196705 
024 7 |2 cas  |a Adjuvants, Immunologic; Nitroblue Tetrazolium, 298-83-9; Plant Extracts; Zymosan, 9010-72-4 
040 |a Scopus  |b spa  |c AR-BaUEN  |d AR-BaUEN 
030 |a JOETD 
100 1 |a Nores, M.M. 
245 1 0 |a Immunomodulatory activities of Cedrela lilloi and Trichilia elegans aqueous leaf extracts 
260 |c 1997 
270 1 0 |m Nores, M.M.; Dpto. Quimica Biologica, Facultad Ciencias Exactas Naturales, Ciudad Universitaria, Pabellon II, Piso 4, (1428) Buenos Aires, Argentina 
506 |2 openaire  |e Política editorial 
504 |a Andrei, G.M., Coulombié, F.C., Courrèges, M.C., De Torres, R.A., Coto, C.E., Meliacine, an antiviral compound from Melia azedarach L., inhibits interferon production (1990) Journal of Interferon Research, 10, pp. 469-475 
504 |a Benencia, F., Courrèges, M.C., Massouh, E.J., Coulombié, F.C., Effect of Melia azedarach L. leaf extracts on human complement and polymorphonuclear leukocytes (1994) Journal of Ethnopharmacology, 41, pp. 53-57 
504 |a Benencia, F., Courrèges, M.C., Nores, M.M., Coulombié, F.C., Immunomodulatory activities of Cedrela tubiflora leaf aqueous extracts (1995) Journal of Ethnopharmacology, 49, pp. 133-139 
504 |a Benencia, F., Courrèges, M.C., Coulombié, F.C., In vitro activities of Cedrela tubiflora aqueous leaf extracts on murine macrophages, polymorphonuclear leukocytes and complement (1996) Phytotherapy Research, 10, pp. 37-41 
504 |a Bhakuni, D.S., Dhar, M.L., Dhar, M.M., Dhawan, B.W., Mehratra, B.N., Screening of plants for biological activity. Part II (1969) Indian Journal of Experimental Biology, 7, pp. 250-262 
504 |a Bray, D.H., Warhurst, D.C., Connolly, J.D., O'Neill, M.J., Phillipson, J.D., Plants as sources of antimalarial drugs. Part 7. Activity of some species of Meliaceae plants and their constituent limonoids (1990) Phytotherapy Research, 4, pp. 29-34 
504 |a Coulombié, F.C., Andrei, G.M., Laguens, R.P., De Torres, R.A., Coto, C.E., Partially purified leaf extracts of Melia azedarach L. inhibit Tacaribe virus growth in neonatal mice (1992) Phytotherapy Research, 6, pp. 15-19 
504 |a Courrèges, M.C., Benencia, F., Coto, C.E., Massouh, E.J., Coulombié, F.C., In vitro antiphagocytic effect of Melia azedarach leaf extracts on mouse peritoneal exudate cells (1994) Journal of Ethnopharmacology, 43, pp. 135-140 
504 |a Fujiwara, T., Takeda, T., Ogihara, Y., Shimizu, M., Nomura, T., Tomita, T., Studies of the structure of polysaccharides from the bark of Melia azadirachta (1982) Chemical and Pharmaceutical Bulletin, 30, pp. 4025-4030 
504 |a Klerx, J.P.A.M., Beukelman, C.J., Van Dijk, H., Willers, J.M.N., Microassay for colorimetric estimation of complement activity in guinea pig, human and mouse serum (1983) Journal of Immunological Methods, 63, pp. 215-220 
504 |a Klerx, J.P.A.M., Van Dijk, H., Van Der Maaden, W.J., Willers, J.M.N., Analytic study of the differential anticomplementary effects of dextran sulphate and heparin in the assay for the mouse alternative pathway (1985) International Archives of Allergy Applied and Immunology, 78, pp. 182-189 
504 |a Klerx, J.P.A.M., Van Oosterhout, A.J.M., Van Dijk, H., Nouwenberg, E.A., Willers, J.M.N., Anticomplementary amines are immunological adjuvants in mice (1985) Immunology Letters, 10, pp. 281-286 
504 |a Labadie, R.P., Van Der Nat, J.M., Simons, J.M., Kroes, B.H., Kosasi, S., Van Der Berg, A.J.J., T'Hart, L.A., De Silva, K.T.D., An ethnopharmacognostic approach to the search of immunomodulators of plant origin (1989) Planta Medica, 55, pp. 339-348 
504 |a Mayer, M.M., (1961) Experimental Immunochemistry, p. 133. , Kabat, E.A. and Mayer, M.M. (Eds.), Charles C. Thomas, Springfield, IL 
504 |a Patel, N.G., Indians traditional medicine: Ayurveda (1986) Folk Medicine: The Art and Science, p. 57. , R.P. Steiner (Ed.), American Chemical Society, Washington, DC 
504 |a Rademaker, P.M., Van Dijk, H., Willers, J.M.N., Involvement of membrane-associated sialic acid in the resistance of sheep erythrocytes to lysis by mouse complement (1981) Immunology Letters, 3, pp. 221-225 
504 |a Toursarkissian, M., (1980) Plantas Medicinales de la Argentina, p. 86. , Hemisferio Sur (Ed.), Buenos Aires, Argentina 
504 |a Van Der Nat, J.M., Klerx, J.P.A.M., Van Dijk, H., De Silva, K.T.D., Labadie, R.P., Immunomodulatory activity of an aqueous extract of Azadirachta indica stem bark (1987) Journal of Ethnopharmacology, 19, pp. 125-131 
504 |a Van Dijk, H., Rademaker, P.M., Willers, J.M.N., Estimation of classical pathway of mouse complement activity by use of sensitized rabbit erythrocytes (1980) Journal of Immunological Methods, 39, pp. 257-268 
504 |a Wilkinson, P.C., Neutrophil function test (1981) Techniques in Clinical Immunology, p. 273. , R.A. Thompson (Ed.), Blackwell Scientific, Oxford 
520 3 |a The effects of Cedrela lilloi and Trichilia elegans (Meliaceae) aqueous leaf extracts on several parameters of the mouse immune system were studied. Both extracts showed a strong anticomplementary activity and inhibited the phagocytosis of opsonized sheep erythrocytes and the activation of the oxidative metabolism by opsonized zymosan on peritoneal macrophages. The in vitro proliferation of spleen T-lymphocytes was also impaired. Furthermore, treatment of mice with the extracts diminished the delayed-type hypersensitivity response to sheep erythrocytes. These results suggest that both extracts exert a marked immunomodulatory effect on the mouse immune system.  |l eng 
536 |a Detalles de la financiación: Universidad de Buenos Aires, EX-063 
536 |a Detalles de la financiación: International Foundation for Science, IFS, F/1384-2 
536 |a Detalles de la financiación: This work was supported by grants from the International Foundation for Science (IFS) N ° F/1384-2 and from the Buenos Aires University (EX-063). 
593 |a Laboratory of Virology, Faculty of Science, University of Buenos Aires, (1428) Buenos Aires, Argentina 
593 |a Laboratorio de Virología, Dpto. Química Biologica, Fac. de Ciencias Exactas y Naturales, Pabellón II, (1428) Buenos Aires, Argentina 
690 1 0 |a CEDRELA LILLOI 
690 1 0 |a IMMUNE SYSTEM 
690 1 0 |a IMMUNOMODULATION 
690 1 0 |a LEAF EXTRACTS 
690 1 0 |a MOUSE 
690 1 0 |a TRICHILIA ELEGANS 
690 1 0 |a PLANT EXTRACT 
690 1 0 |a ZYMOSAN 
690 1 0 |a AEROBIC METABOLISM 
690 1 0 |a ANIMAL CELL 
690 1 0 |a ANIMAL EXPERIMENT 
690 1 0 |a ANIMAL MODEL 
690 1 0 |a ARTICLE 
690 1 0 |a COMPLEMENT INHIBITION 
690 1 0 |a CONTROLLED STUDY 
690 1 0 |a DELAYED HYPERSENSITIVITY 
690 1 0 |a FEMALE 
690 1 0 |a IMMUNOMODULATION 
690 1 0 |a LYMPHOCYTE CULTURE 
690 1 0 |a LYMPHOCYTE PROLIFERATION 
690 1 0 |a MEDICINAL PLANT 
690 1 0 |a MOUSE 
690 1 0 |a NONHUMAN 
690 1 0 |a PERITONEUM MACROPHAGE 
690 1 0 |a PHAGOCYTOSIS 
690 1 0 |a PLANT LEAF 
690 1 0 |a SHEEP ERYTHROCYTE 
690 1 0 |a SPLEEN LYMPHOCYTE 
690 1 0 |a SUBCUTANEOUS DRUG ADMINISTRATION 
690 1 0 |a T LYMPHOCYTE 
690 1 0 |a TRADITIONAL MEDICINE 
690 1 0 |a ADJUVANTS, IMMUNOLOGIC 
690 1 0 |a ANIMALS 
690 1 0 |a CELL SEPARATION 
690 1 0 |a COMPLEMENT ACTIVATION 
690 1 0 |a ERYTHROCYTES 
690 1 0 |a FEMALE 
690 1 0 |a HYPERSENSITIVITY, DELAYED 
690 1 0 |a LYMPHOCYTE ACTIVATION 
690 1 0 |a MACROPHAGES, PERITONEAL 
690 1 0 |a MICE 
690 1 0 |a MICE, INBRED BALB C 
690 1 0 |a NITROBLUE TETRAZOLIUM 
690 1 0 |a PHAGOCYTOSIS 
690 1 0 |a PLANT EXTRACTS 
690 1 0 |a PLANT LEAVES 
690 1 0 |a SHEEP 
690 1 0 |a T-LYMPHOCYTES 
690 1 0 |a ZYMOSAN 
651 4 |a ARGENTINA 
651 4 |a ARGENTINA 
700 1 |a Courrèges, M.C. 
700 1 |a Benencia, F. 
700 1 |a Coulombié, F.C. 
773 0 |d 1997  |g v. 55  |h pp. 99-106  |k n. 2  |p J. ETHNOPHARMACOL.  |x 03788741  |w (AR-BaUEN)CENRE-5563  |t Journal of Ethnopharmacology 
856 4 1 |u https://www.scopus.com/inward/record.uri?eid=2-s2.0-0343196705&doi=10.1016%2fS0378-8741%2896%2901480-8&partnerID=40&md5=681c8a3caff4cba7660d68d26f1a664a  |y Registro en Scopus 
856 4 0 |u https://doi.org/10.1016/S0378-8741(96)01480-8  |y DOI 
856 4 0 |u https://hdl.handle.net/20.500.12110/paper_03788741_v55_n2_p99_Nores  |y Handle 
856 4 0 |u https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03788741_v55_n2_p99_Nores  |y Registro en la Biblioteca Digital 
961 |a paper_03788741_v55_n2_p99_Nores  |b paper  |c PE 
962 |a info:eu-repo/semantics/article  |a info:ar-repo/semantics/artículo  |b info:eu-repo/semantics/publishedVersion 
999 |c 64306