Rhodanese and ALA-S in mammary tumor and liver from normal and tumor-bearing mice

1. 1. Basal levels and allyl-isopropylacetamide (AIA) or veronal induced levels of δ-amino-levulinate synthetase (ALA-S), cytoplasmic and mitochondrial rhodanese were determined in tumor (T) and liver of both normal mice (NM) and T-bearing mice (TBM). 2. 2. Rhodanese tumoral mitochondrial levels wer...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autor principal: Navone, N.M
Otros Autores: Vázquez, E.S, Polo, C.F, del C. Batlle, A.M
Formato: Capítulo de libro
Lenguaje:Inglés
Publicado: 1992
Acceso en línea:Registro en Scopus
DOI
Handle
Registro en la Biblioteca Digital
Aporte de:Registro referencial: Solicitar el recurso aquí
LEADER 08013caa a22009137a 4500
001 PAPER-333
003 AR-BaUEN
005 20230518202942.0
008 190411s1992 xx ||||fo|||| 00| 0 eng|d
024 7 |2 scopus  |a 2-s2.0-0026514861 
024 7 |2 cas  |a 5-Aminolevulinate Synthetase, EC 2.3.1.37; Allylisopropylacetamide, 299-78-5; Barbital, 57-44-3; Thiosulfate Sulfurtransferase, EC 2.8.1.1 
040 |a Scopus  |b spa  |c AR-BaUEN  |d AR-BaUEN 
100 1 |a Navone, N.M. 
245 1 0 |a Rhodanese and ALA-S in mammary tumor and liver from normal and tumor-bearing mice 
260 |c 1992 
270 1 0 |m del C. Batlle, A.M.; Centro de Investigaciones sobre Porfirinas y Porfirias (CIPYP) (CONICET, FCEN, UBA), Ciudad Universitaria, Pabellon II, 2do. Piso, 1428 Buenos Aires, Argentina 
506 |2 openaire  |e Política editorial 
504 |a Beck, Dedmond, Ouellette, Biochemical basis for impaired drug metabolism in tumor bearing rats (1982) Biochem. Pharmac., 31, pp. 1535-1543 
504 |a Bonkowsky, Tschudy, Collins, Doherty, Control of δ-aminolevulinic acid synthetase and tyrosine aminotransferse in tumors and livers of tumor bearing rats (1973) J. natn. Cancer Inst., 50, pp. 1215-1225 
504 |a Cerletti, Seeking a better job for an underemployed enzyme: rhodanese (1986) TIBS, 11, pp. 369-372 
504 |a Finazzi Agró, Federici, Giovagnoli, Cannella, Cavallini, Effect of sulfur binding on rhodanese fluorescence (1972) European Journal of Biochemistry, 28, pp. 89-93 
504 |a Inoue, Oyama, Tuboi, On the nature of the activating enzyme of the inactive form of δ-aminolevulinate synthetase in Rhodopseudomonas spheroides (1979) J. Biochem., 86, pp. 477-482 
504 |a Lowry, Rosebrough, Farr, Randall, Protein measurement with the Folin-phenol reagent (1951) J. biol. Chem., 193, pp. 265-275 
504 |a Marver, Tschudy, Perlroth, Collins, δ-aminolevulinic acid synthetase. I. Studies in liver homogenates (1966) J. biol. Chem., 241, pp. 2803-2809 
504 |a Navone, Polo, Dinger, Batlle, Heme regulation in mouse mammary carcinoma and liver of tumor bearing mice. I. Effect of allyl-isopropylacetamide and veronal on δ-aminolevulinate synthetase, cytochrome P-450 and cytochrome oxidase (1990) Int. J. Biochem., 22, pp. 1005-1008 
504 |a Ploegman, Drent, Kalk, Hol, Structure of bovine liver rhodanese. I. The structure determination at 2.5 A resolution and a comparison of the conformation and sequence of its two domains (1978) J. molec. Biol., 123, pp. 557-594 
504 |a Rosenthal, The distribution of rhodanese (1948) Fedn. Proc., 7, pp. 181-182 
504 |a Sörbo, Crystalline rhodanese I Purification and physiocochemical examination (1953) Acta Chemica Scandinavica, 7, pp. 1129-1136 
504 |a Vásquez, Wider de Xifra, Batlle, Porphyrin biosynthesis in the soybean callus tissue system XVIII. Levels of succinyl CoA synthetase, cysthationase, rhodanese, aminolevulinate synthetase and aminolevulinate dehydratase in clones of different age (1980) Int. J. Biochem., 12, pp. 721-724 
504 |a Vázquez, Buzaleh, Wider, Batlle, Reduced thiosulphate affinity for erythrocyte rhodanese: an explanation for increased δ-aminolevulinic synthetase activity in some porphyrias? (1986) IRCS Med. Sci., 14, pp. 999-1000 
504 |a Vázquez, Buzaleh, Wider, Batlle, Red blood cell rhodanese: its possible role in modulating δ-amino-laevulinate synthetase activity in mammals (1987) Int. J. Biochem., 19, pp. 217-219 
504 |a Viale, Wider de Xifra, Battle, Porphyrin biosynthesis in Rhodopseudomonas palustris—II. Evidence on the existence of a factor regulating aminolevulinate synthetase activity (1980) Int. J. Biochem., 12, pp. 729-733 
504 |a Westley, (1973) Rhodanese in Advances in Enzymology, 39, pp. 327-368. , A. Meister, Interscience, New York 
504 |a Westley, Thiosulphate cyanide sulfotransferase (rhodanese) (1981) Meth. Enzymol., 77, pp. 285-291 
504 |a Wider de Xifra, Sandy, Davies, Neuberger, Control of δ-aminolaevulinate synthetase activity in Rhodopseudomonas spheroides (1976) Phil. Trans. R. Soc. B, 273, pp. 79-98 
520 3 |a 1. 1. Basal levels and allyl-isopropylacetamide (AIA) or veronal induced levels of δ-amino-levulinate synthetase (ALA-S), cytoplasmic and mitochondrial rhodanese were determined in tumor (T) and liver of both normal mice (NM) and T-bearing mice (TBM). 2. 2. Rhodanese tumoral mitochondrial levels were higher than the hepatic normal mitochondrial fraction, while the cytoplasmic activity was nearly equal in all sources. 3. 3. In neither case was the activity of tumoral ALA-S and rhodanese altered by any of the porphyrinogenic drugs. 4. 4. Mitochondrial and cytoplasmic rhodanese activity was also measured in tumor and liver of TBM at different intervals after transplantation. We concluded that the behaviour of rhodanese is a property inherent to the tissue and not one attained with time. © 1992.  |l eng 
536 |a Detalles de la financiación: National Research Council 
536 |a Detalles de la financiación: Ministerio de la Producción, Ciencia y Tecnología 
536 |a Detalles de la financiación: Association for International Cancer Research, AICR 
536 |a Detalles de la financiación: Consejo Nacional de Investigaciones Científicas y Técnicas 
536 |a Detalles de la financiación: Association for International Cancer Research, AICR 
536 |a Detalles de la financiación: Acknowledgements--E. Vfizquez and A. M. del C. Batlle are members of the Career of Scientific Research at the National Research Council (CONICET), C. Polo and N. Navone are Research Assistants at the CONICET. This work was supported by grants from the CONICET and the Association for International Cancer Research (AICR), U.K.A.M. del C. Batlle thanks the Ministerio de Educaci6n y Ciencia, Spain for special help. We thank Dr N. Andrade and Dr S. Bonaparte from the Instituto Nacional de Oncologia "Angel H. Roffo" for providing us with the original tumor specimens for transplantation. We are most grateful to Lic Susana Afonso for the excellent drawings. 
593 |a Centro de Investigaciones sobre Porfirinas y Porfirias (CIPYP) (CONICET, FCEN, UBA), Ciudad Universitaria, Pabellon II, 2do. Piso, 1428 Buenos Aires, Argentina 
690 1 0 |a THIOSULFATE SULFURTRANSFERASE 
690 1 0 |a ANIMAL EXPERIMENT 
690 1 0 |a ARTICLE 
690 1 0 |a BREAST TUMOR 
690 1 0 |a LIVER 
690 1 0 |a MITOCHONDRION 
690 1 0 |a MOUSE 
690 1 0 |a NONHUMAN 
690 1 0 |a PRIORITY JOURNAL 
690 1 0 |a 5-AMINOLEVULINATE SYNTHETASE 
690 1 0 |a ALLYLISOPROPYLACETAMIDE 
690 1 0 |a ANIMAL 
690 1 0 |a BARBITAL 
690 1 0 |a CYTOPLASM 
690 1 0 |a ENZYME INDUCTION 
690 1 0 |a LIVER 
690 1 0 |a MALE 
690 1 0 |a MAMMARY NEOPLASMS, EXPERIMENTAL 
690 1 0 |a MICE 
690 1 0 |a MICE, INBRED BALB C 
690 1 0 |a MITOCHONDRIA 
690 1 0 |a SUPPORT, NON-U.S. GOV'T 
690 1 0 |a THIOSULFATE SULFURTRANSFERASE 
690 1 0 |a ANIMALIA 
700 1 |a Vázquez, E.S. 
700 1 |a Polo, C.F. 
700 1 |a del C. Batlle, A.M. 
773 0 |d 1992  |g v. 102  |h pp. 83-85  |k n. 1  |x 03050491  |w (AR-BaUEN)CENRE-2752  |t Comparative Biochemistry and Physiology -- Part B: Biochemistry and 
856 4 1 |u https://www.scopus.com/inward/record.uri?eid=2-s2.0-0026514861&doi=10.1016%2f0305-0491%2892%2990276-W&partnerID=40&md5=5409e856726afab35ea68fb5788860a2  |y Registro en Scopus 
856 4 0 |u https://doi.org/10.1016/0305-0491(92)90276-W  |y DOI 
856 4 0 |u https://hdl.handle.net/20.500.12110/paper_03050491_v102_n1_p83_Navone  |y Handle 
856 4 0 |u https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03050491_v102_n1_p83_Navone  |y Registro en la Biblioteca Digital 
961 |a paper_03050491_v102_n1_p83_Navone  |b paper  |c PE 
962 |a info:eu-repo/semantics/article  |a info:ar-repo/semantics/artículo  |b info:eu-repo/semantics/publishedVersion 
963 |a VARI 
999 |c 61286