Conjugal transfer of bacteriophage resistance to prolate phages in Lactococcus lactis

Conjugal transfer of lactose-fermenting ability (Lac+) and lytic phage resistance (Lpr+) was demonstrated in four matings between Lactococcus lactis ssp. lactis C2, phage resistant mutant donor strains C21, C23 and C26 and the C2 derivative LM2302 plasmid free recipient strain. Transconjugants were...

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Autor principal: De Fabrizio, S.V
Otros Autores: Ledford, R.A, Parada, J.L, Pan, C.L
Formato: Capítulo de libro
Lenguaje:Inglés
Publicado: 1992
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024 7 |2 scopus  |a 2-s2.0-0004388965 
040 |a Scopus  |b spa  |c AR-BaUEN  |d AR-BaUEN 
030 |a FOMIE 
100 1 |a De Fabrizio, S.V. 
245 1 0 |a Conjugal transfer of bacteriophage resistance to prolate phages in Lactococcus lactis 
260 |c 1992 
270 1 0 |m Fabrizio, S.V.d.; Laboratorio de Microbiologia de Alimentos, Facultad de Ciencias Exactas y Naturales-UBA, Buenos Aires, Argentina 
506 |2 openaire  |e Política editorial 
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504 |a Sanders, Leonhard, Sing, Klaenhammer, Conjugal strategy for construction of fast acid-producing, bacteriophage-resistant lactic streptococci for use in dairy fermentations (1986) Appl. Environ. Microbiol., 52, pp. 1001-1007 
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520 3 |a Conjugal transfer of lactose-fermenting ability (Lac+) and lytic phage resistance (Lpr+) was demonstrated in four matings between Lactococcus lactis ssp. lactis C2, phage resistant mutant donor strains C21, C23 and C26 and the C2 derivative LM2302 plasmid free recipient strain. Transconjugants were selected with Lac+ Emr and/or Str phenotypes. Lac+ was transferred from donor strains to Lac- Emr and r Str phage sensitive recipient strains at a frequency of 10-6 to 10-8 revealing that Lac+ and subsequently Lpr+ were transferred. Although clumping (Clu) effects with a subsequent high frequency transconjugation (Hft) have been observed before in related strains, it was not evident in this case. Phage assays with Argentine (ARG) and United States (US) phage revealed that recipient strains were Lpr-. Because the transconjugants had the same lytic pattern as the corresponding donor strain, it is apparent that the unselected Lpr+ trait was cotransferred with the Lac+ marker on a 45 kb plasmid. A significant reduction in bacteriophage adsorption and failures in plaque formations for the ARG and the US prolate phages in all Lpr+ strains was also observed. These results suggest that the Lpr+ trait is mobilized by conjugal transfer. © 1992 Academic Press Limited.  |l eng 
536 |a Detalles de la financiación: Umweltbundesamt 
536 |a Detalles de la financiación: Secretaria de Ciencia y Tecnica, Universidad de Buenos Aires 
536 |a Detalles de la financiación: The authors acknowledge the financial support from Secretaria de Ciencia y Tecnica, UBA and Consejo National de Investigaciones Cientificas y Tecnicas 
593 |a Laboratorio de Microbiologia de Alimentos, Facultad de Ciencias Exactas y Naturales-UBA, Buenos Aires, Argentina 
593 |a Institute of Food Science, Cornell University, Ithaca, NY 14853, United States 
700 1 |a Ledford, R.A. 
700 1 |a Parada, J.L. 
700 1 |a Pan, C.L. 
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