Early inhibition of DNA synthesis in the developing rat cerebral cortex by the purine analogues olomoucine and roscovitine

The effects of the cyclin-dependent kinase (CDK) inhibitors olomoucine and roscovitine on DNA synthesis were studied using short time incubation (30-90 minutes). Both purine analogues at concentrations from 1-100 μM decreased the DNA synthesis of rat brain cortex in a dose-dependent manner and the m...

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Autor principal: Yakisich, J.S
Otros Autores: Sidén, A., Vargas, V.I, Eneroth, P., Cruz, M.
Formato: Capítulo de libro
Lenguaje:Inglés
Publicado: Academic Press Inc. 1998
Acceso en línea:Registro en Scopus
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