7-Hydroxywithanolides from Datura ferox

Three new withanolides were isolated from leaves of Datura ferox. Their structures were established as (17R,20S,22R)-5α,6α,7β,12α-tetrahydroxy- 1-oxowitha-2,24-dienolide (1), (17R,20S,22R,24S,25S)-24,25-epoxy- 5α,6α,7β,12α-tetrahydroxy-1-oxowitha-2-enolide (2), and (17R,20S,22R)- 5α,6α-epoxy-7α-hydr...

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Detalles Bibliográficos
Autor principal: Veleiro, A.S
Otros Autores: Cirigliano, A.M, Oberti, J.C, Burton, G.
Formato: Capítulo de libro
Lenguaje:Inglés
Publicado: 1999
Acceso en línea:Registro en Scopus
DOI
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Registro en la Biblioteca Digital
Aporte de:Registro referencial: Solicitar el recurso aquí
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024 7 |2 cas  |a withanolide, 40326-62-3 
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030 |a JNPRD 
100 1 |a Veleiro, A.S. 
245 1 0 |a 7-Hydroxywithanolides from Datura ferox 
260 |c 1999 
270 1 0 |m Burton, G.; Departamento de Quimica Organica, Fac. de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Ciudad Universitaria, 1428 Buenos Aires, Argentina; email: burton@qo.fcen.uba.ar 
506 |2 openaire  |e Política editorial 
504 |a Ray, A.B., Gupta, M., (1994) Prog. Chem. Org. Nat. Prod., 63, pp. 1-106 
504 |a Baumann, T.W., Meier, C.M., (1993) Phytochemistry, 33, pp. 317-321 
504 |a Cirigliano, A.M., Veleiro, A.S., Oberti, J.C., Burton, G., (1995) Phytochemistry, 40, pp. 611-613 
504 |a Evans, W.C., Grout, R.J., Mensah, M.L.K., (1984) Phytochemistry, 23, pp. 1717-1720 
504 |a Kalla, A.K., Raina M, L., Dhar, K.L., Qurishi, M.A., Snatzke, G., (1979) Phytochemistry, 18, pp. 637-640 
504 |a Besalle, R., Lavie, D., Frolow, F., (1987) Phytochemistry, 26, pp. 1797-1800 
504 |a Haasnoot, C.A.G., De Leew, F.A.A.M., Altona, C., (1980) Tetrahedron, 36, pp. 2783-2792 
520 3 |a Three new withanolides were isolated from leaves of Datura ferox. Their structures were established as (17R,20S,22R)-5α,6α,7β,12α-tetrahydroxy- 1-oxowitha-2,24-dienolide (1), (17R,20S,22R,24S,25S)-24,25-epoxy- 5α,6α,7β,12α-tetrahydroxy-1-oxowitha-2-enolide (2), and (17R,20S,22R)- 5α,6α-epoxy-7α-hydroxy-1,12-dioxowitha-2,24-dienolide (3), using spectroscopic methods (NMR, MS) and molecular modeling.  |l eng 
593 |a Depto. de Quimica Organica, Fac. de Ciencias Exactas y Naturales, Ciudad Universitaria, (1428) Buenos Aires, Argentina 
593 |a Depto. de Quimica Organica, Facultad de Ciencias Químicas, Univ. Nacional de Córdoba, Casilla 61, 500 Córdoba, Argentina 
690 1 0 |a WITHANOLIDE 
690 1 0 |a ARTICLE 
690 1 0 |a DRUG ISOLATION 
690 1 0 |a DRUG STRUCTURE 
690 1 0 |a MASS SPECTROMETRY 
690 1 0 |a MOLECULAR MODEL 
690 1 0 |a NONHUMAN 
690 1 0 |a NUCLEAR MAGNETIC RESONANCE 
690 1 0 |a PLANT LEAF 
690 1 0 |a DATURA FEROX 
700 1 |a Cirigliano, A.M. 
700 1 |a Oberti, J.C. 
700 1 |a Burton, G. 
773 0 |d 1999  |g v. 62  |h pp. 1010-1012  |k n. 7  |p J. Nat. Prod.  |x 01633864  |t Journal of Natural Products 
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856 4 0 |u https://doi.org/10.1021/np980320k  |y DOI 
856 4 0 |u https://hdl.handle.net/20.500.12110/paper_01633864_v62_n7_p1010_Veleiro  |y Handle 
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