Intracranial aneurysm wall motion and wall shear stress from 4D computerized tomographic angiography images

It is widely accepted that wall shear stress is associated to aneurysm formation, growth and rupture. Early identification of potential risk factors may contribute to decide the treatment and improve patient care. Previous studies have shown associations between high aneurysm wall shear stress value...

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Autor principal: Castro, M.A
Otros Autores: Olivares, M.C.A, Putman, C.M, Cebral, J.R
Formato: Acta de conferencia Capítulo de libro
Lenguaje:Inglés
Publicado: 2013
Acceso en línea:Registro en Scopus
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040 |a Scopus  |b spa  |c AR-BaUEN  |d AR-BaUEN 
100 1 |a Castro, M.A. 
245 1 0 |a Intracranial aneurysm wall motion and wall shear stress from 4D computerized tomographic angiography images 
260 |c 2013 
270 1 0 |m Grupo de Investigación Y Desarrollo en Bioingeniería, Regional Buenos Aires, CONICET, Universidad Tecnológica Nacional, Medrano 951, Ciudad de Buenos Aires, CP 1179, Argentina 
506 |2 openaire  |e Política editorial 
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504 |a Cebral, J.R., Castro, M.A., Burgess, J.E., Pergolizi, R.S., Sheridan, M.J., Putman, C.M., Characterization of cerebral aneurysmfor assessing risk of rupture using patient-specific computational hemodynamics models (2005) Am J Neuroradiol, 26, pp. 2550-2559 
504 |a Castro, M.A., Putman, C.M., Cebral, J.R., Hemodynamic patterns of anterior communicating artery aneurysms: A possible association with rupture (2009) Am J Neuroradiol, 30 (2), pp. 297-302 
504 |a Castro, M.A., Putman, C.M., Radaelli, A., Frangi, A.F., Cebral, J.R., Hemodynamics and rupture of terminal cerebral aneurysms (2009) Acad Radiol, 16 (19), pp. 1201-1207 
504 |a Shojima, M., Oshima, M., Takagi, K., Torii, R., Hayakawa, M., Katada, K., Morita, A., Kirino, T., Magnitude and role of wall shear stress on cerebral aneurysm: Computational fluid dynamic study of 20 middle cerebral artery aneurysms (2004) Stroke, 35, pp. 2500-2505 
504 |a Castro, M.A., Putman, C.M., Cebral, J.R., Computational fluid dynamics modeling of intracranial aneurysms: Effects of parent artery segmentation on intra-aneurysmal hemodynamics (2006) Am J Neuroradiol, 27, pp. 1703-1709 
504 |a Castro, M.A., Putman, C.M., Cebral, J.R., Effects of parent vessel geometry on intraaneurysmal flow pattern (2006) Proc. SPIE Medical Imaging 2006: Physics of Medical Imaging Image Reconstruction, 6143, pp. 123-131 
504 |a Cebral, J.R., Sheridan, M.J., Putman, C.M., Hemodynamics and bleb formation in intracranial aneurysms (2010) Am J Neuroradiol, 31, pp. 304-310 
504 |a Castro, M.A., Putman, C.M., Cebral, J.R., Computational analysis of anterior communicating artery aneurysm shear stress before and after aneurysm formation (2011) Journal of Physics C.S., 32, pp. 1-7 
504 |a Kulcsar, Z., Ugron, A., Marosfo, M., Berentei, Z., Paal, G., Szikora, I., Hemodynamics of cerebral aneurysm initiation: The role of wall shear stress and spatial wall shear stress gradient (2011) Am J Neuroradiol, 32 (3), pp. 587-594 
504 |a Yaghmai, V., Rohany, M., Shaibani, A., Huber, M., Soud, H., Russell, E.J., Walker, M.T., Pulsatility imaging of saccular aneurysm model by 64-slice CT with dynamic multiscan technique (2007) J Vasc Intervent Radiol, 18, pp. 785-788 
504 |a Boecher-Schwarz, H.G., Ringel, K., Kopacz, L., Heimann, A., Kempski, O., Ex vivo study of the physical effect of coils on pressure and flow dynamics in experimental aneurysms (2000) Am J Neuroradiol, 21, pp. 1532-1536 
504 |a Ueno, J., Matsuo, T., Sugiyama, K., Okeda, R., Mechanism underlying the prevention of aneurismal rupture by coil embolization (2002) J Med Dental Sci., 49, pp. 135-141 
504 |a Zhang, C., Villa Uriol, M.C., De Craene, M., Pozo, J.M., Frangi, A.F., Time-resolved 3D rotational angiography reconstruction: Towards cerebral aneurysm pulsatile analysis (2008) Int J Comput Assist Radiol Surg, 3, pp. S44-S46 
504 |a Oubel, E., Cebral, J.R., De Craene, M., Blanc, R., Blasco, R., Macho, J., Putman, C.M., Frangi, A.F., Wall motion setimation in intracranial aneurysms (2010) Physiol Meas, 31, pp. 1119-1135 
504 |a Dempere-Marco, L., Oubel, E., Castro, M.A., Putman, C.M., Frangi, A.F., Cebral, J.R., Estimation of wall motion in intracranial aneurysms and its effects on hemodynamic patterns (2006) Lecture Notes in Computer Science, 4191, pp. 438-445 
504 |a Castro, M.A., Putman, C.M., Cebral, J.R., Computational hemodynamics of cerebral aneurysms: Assessing the risk of rupture (2008) VDM, , Verlag 
504 |a Yim, P., Vasbinder, G.B., Ho, V.B., Choyke, P.L., Isosurfaces as deformable models for magnetic resonance angiography (2003) IEEE - Trans Med Imag, 22 (7), pp. 875-881 
504 |a Löhner, R., Extensions and improvements of the advancing front grid generation technique (1996) Comp Meth App Mech Eng, 5, pp. 119-132 
504 |a Löhner, R., Regridding surface triangulations (1996) J Comput Phys, 126, pp. 1-10 
504 |a Löhner, R., Automatic unstructured grid generators (1997) Finite Elements Analysis Design, 25, pp. 111-134 
504 |a Mazumdar, J.N., (1992) Biofluid Mechanics, , World Scientific, Singapore 
504 |a Cebral, J.R., Castro, M.A., Putman, C.M., Alperin, N., Flow-area relationship in internal carotid and vertebral arteries (2008) Physiol Meas, 29 (10), pp. 585-594 
504 |a Sherman, T.F., On connecting large vessels to small, The meaning of Murray's law (1981) J Gen Physiol, 78, pp. 431-453 
504 |a Womersley, J.R., Method for the calculation of velocity, rate of flow and viscous drag in arteries when the pressure gradient is known (1955) J Physiol, 127, pp. 553-563 
504 |a Taylor, C.A., Hughes, T.J.R., Zarins, C.K., Finite element modeling of blood flow in arteries (1998) Comp Meth Appl Mech Engin, 158, pp. 155-196 
504 |a Cebral, J.R., Castro, M.A., Appanaboyina, S., Putman, C., Millán, D., Frangi, A., Efficient pipeline for image- based patient-specific analysis of cerebral aneurysms hemodynamics: Technique and sensitivity (2005) IEEE - Trans Med Imag - Special Issue on Vascular Imaging, 24 (4), pp. 457-467A4 - The Society of Photo-Optical Instrumentation Engineers (SPIE); Aeroflex Incorporated; CREOL - Univ. Central Florida, Coll. Opt. Photonics; DQE Instruments, Inc.; Medtronic, Inc.; PIXELTEQ, Multispectral Sensing and Imaging 
520 3 |a It is widely accepted that wall shear stress is associated to aneurysm formation, growth and rupture. Early identification of potential risk factors may contribute to decide the treatment and improve patient care. Previous studies have shown associations between high aneurysm wall shear stress values and both elevated risk of rupture and regions of aneurysm growing. Based on the assumption that damaged regions of the endothelium have different mechanical properties, regions with differentiated wall displacement amplitudes are expected. A previous approach based on the analysis of bidimensional dynamic tomographic angiography had been designed to investigate those correlations, but its main limitation was that wall motion was measured in a selected plane. The purpose of this work is to overcome some of those limitations. High time and spatial resolution 4D computerized tomographic angiography images of cerebral aneurysms were acquired and analyzed in order to identify and characterize wall motion. Images were filtered and segmented at nineteen time points during the cardiac cycle and displacement was estimated within the aneurysm sac and compared to wall shear stress distributions from patient-specific unsteady finite element blood flow simulations. © 2013 SPIE.  |l eng 
593 |a Grupo de Investigación Y Desarrollo en Bioingeniería, Regional Buenos Aires, CONICET, Universidad Tecnológica Nacional, Medrano 951, Ciudad de Buenos Aires, CP 1179, Argentina 
593 |a De Ingeniería Ciencias Exactas y Naturales, Universidad Favaloro, Solís 453, Ciudad de Buenos Aires, CP 1078, Argentina 
593 |a Interventional Neuroradiology, Inova Fairfax Hospital, 3300 Gallows Road, Falls Church, VA, United States 
593 |a Center for Computational Fluid Dynamics, George Mason University, Fairfax, VA, United States 
690 1 0 |a 4DCTA 
690 1 0 |a CEREBRAL ANEURYSMS 
690 1 0 |a IMAGE SEGMENTATION 
690 1 0 |a WALL MOTION 
690 1 0 |a WALL SHEAR STRESS 
690 1 0 |a 4DCTA 
690 1 0 |a ANGIOGRAPHY IMAGES 
690 1 0 |a BLOOD FLOW SIMULATIONS 
690 1 0 |a CEREBRAL ANEURYSMS 
690 1 0 |a DISPLACEMENT AMPLITUDES 
690 1 0 |a INTRACRANIAL ANEURYSMS 
690 1 0 |a WALL MOTION 
690 1 0 |a WALL SHEAR STRESS 
690 1 0 |a HEMODYNAMICS 
690 1 0 |a IMAGE SEGMENTATION 
690 1 0 |a MECHANICAL PROPERTIES 
690 1 0 |a MEDICAL APPLICATIONS 
690 1 0 |a MOLECULAR IMAGING 
690 1 0 |a PATIENT TREATMENT 
690 1 0 |a TOMOGRAPHY 
690 1 0 |a ANGIOGRAPHY 
700 1 |a Olivares, M.C.A. 
700 1 |a Putman, C.M. 
700 1 |a Cebral, J.R. 
711 2 |c Lake Buena Vista, FL  |d 10 February 2013 through 13 February 2013  |g Código de la conferencia: 97194 
773 0 |d 2013  |g v. 8672  |p Progr. Biomed. Opt. Imaging Proc. SPIE  |n Progress in Biomedical Optics and Imaging - Proceedings of SPIE  |x 16057422  |z 9780819494467  |t Medical Imaging 2013: Biomedical Applications in Molecular, Structural, and Functional Imaging 
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