Future advances in pulmonary arterial hypertension

Over the last decade has witnessed extensive progress in basic and clinical research in the field of pulmonary arterial hypertension (PAH). International PAH registries have achieved much to advance our understanding of the epidemiology, demographics, etiology, clinical course, hemodynamics, disease...

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Autor principal: Bevacqua, R.J
Otros Autores: Perrone, S.V
Formato: Capítulo de libro
Lenguaje:Inglés
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Publicado: 2013
Acceso en línea:Registro en Scopus
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100 1 |a Bevacqua, R.J. 
245 1 0 |a Future advances in pulmonary arterial hypertension 
246 3 1 |a Avances futuros en la hipertensión arterial pulmonar 
260 |c 2013 
270 1 0 |m Perrone, S. V.Montañeses 2325, CP: C1428AQK, Ciudad Autónoma de Buenos Aires, Argentina; email: svperrone@netizen.com.ar 
506 |2 openaire  |e Política editorial 
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504 |a Bevacqua, R.J., Bortman, G., Perrone, S.V., Antagonistas de los receptores de la endotelina para la hipertensión arterial pulmonar (2013) Insuf Card, 8 (2), pp. 77-94 
504 |a Benza, R.L., Miller, D.P., Gomberg-Maitland, M., Predicting survival in pulmonary arterial hypertension: Insights from the Registry to Evaluate Early and Long-Term Pulmonary Arterial Hypertension Disease Management (REVEAL) (2010) Circulation, 122, pp. 164-172 
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504 |a Galiè, N., Hoeper, M.M., Humbert, M., Guidelines for the diagnosis and treatment of pulmonary hypertension: The Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS), endorsed by the International Society of Heart and Lung Transplantation (ISHLT) (2009) Eur Heart J, 30, pp. 2493-2537 
504 |a Naval, N., Clasificación actual de la hipertensión pulmonar (2011) Insuf Card, 6 (1), pp. 30-38 
504 |a Bortman, G., Presentación clínica y clasificación actual de la hipertensión arterial pulmonar (2009) Insuf Card, 4 (1), pp. 27-32 
504 |a Simonneau, G., Robbins, I.M., Beghetti, M., Updated clinical classification of pulmonary hypertension (2009) J Am Coll Cardiol, 54 (SUPPL. 1), pp. S43-S54 
504 |a Humbert, M., Souza, R., Galiè, N., McLaughlin, V., Simonneau, G., Rubin, L., Pulmonary arterial hypertension: Bridging the present to the future (2012) Eur Respir Rev, 21, pp. 126+267-270 
504 |a Bichara, V.M., Ventura, H.O., Perrone, S.V., Hipertensión pulmonar: La mirada del especialista (2011) Insuf Card, 6, pp. 65-79 
504 |a Mazzei, J.A., Cáneva, J.O., Perrone, S.V., Melero, M.J., Scali, J.J., Bortman, G., Actualización en el diagnostico y tratamiento de la hipertensión pulmonar (2011) Medicina (B Aires), 71 (SUPPL. 1), pp. 1-48 
504 |a Caroli, C., Yaman, B., Embón, M., Cohen Arazi, H., Perrone, S.V., Resonancia magnética nuclear en la evaluación de la hipertensión pulmonar (2009) Insuf Card, 4 (2), pp. 82-84 
504 |a Perrone, S.V., Estrategia terapéutica en el tratamiento de la hipertensión arterial pulmonar (2009) Insuf Card, 4 (1), pp. 33-43 
504 |a Mazzei, J.A., Hipertensión pulmonar en las enfermedades respiratorias crónicas. Prueba de marcha de 6 minutos: Técnica y utilidad en el diagnóstico funcional, pronóstico y seguimiento (2013) Insuf Card, 8 (3), pp. 125-133 
504 |a Mazzei, J.A., Mecanismos fisiopatológicos involucrados y diagnóstico de la hipertensión arterial pulmonar (2009) Insuf Card, 4 (1), pp. 3-10 
504 |a Condliffe, R., Kiely, D.G., Peacock, A.J., Connective tissue disease associated pulmonary arterial hypertension in the modern treatment era (2009) Am J Respir Crit Care Med, 179, pp. 151-157 
504 |a Dimopoulos, K., Inuzuka, R., Goletto, S., Improved survival among patients with Eisenmenger syndrome receiving advanced therapy for pulmonary arterial hypertension (2010) Circulation, 121, pp. 20-25 
504 |a Vachiéry, J.-L., Gaine, S., Challenges in the diagnosis and treatment of pulmonary arterial hypertension (2012) Eur Respir Rev, 21, pp. 313-320 
504 |a Galiè, N., Rubin, L.J., Hoeper, M., Treatment of patients with mildly symptomatic pulmonary arterial hypertension with bosentan (EARLY study): A double-blind, randomised controlled trial (2008) Lancet, 371, pp. 2093-2100 
504 |a Frost, A.E., Badesch, D.B., Barst, R.J., The changing picture of patients with pulmonary arterial hypertension in the United States: How REVEAL differs from historic and non-US Contemporary Registries (2011) Chest, 139, pp. 128-137 
504 |a Barimboim, E., Hipertensión pulmonar en las enfermedades del tejido conectivo: Nuevas perspectivas ante un problema de difícil resolución (2009) Insuf Card, 4 (3), pp. 101-106 
504 |a Sánchez Román, J., Diagnostico y tratamiento de la hipertensión pulmonar en pacientes con esclerodermia (2012) Insuf Card, 7 (1), pp. 16-28 
504 |a Humbert, M., Yaici, A., de Groote, P., Screening for pulmonary arterial hypertension in patients with systemic sclerosis: Clinical characteristics at diagnosis and long-term survival (2011) Arthritis Rheum, 63, pp. 3522-3530 
504 |a Humbert, M., Coghlan, J.G., Khanna, D., Early detection and management of pulmonary arterial hypertension (2012) Eur Respir Rev, 21, pp. 306-312 
504 |a Bichara, V.M., Tazar, J., Ventura, H.O., El ecocardiograma como herramienta para el diagnóstico y la evaluación de los pacientes con insuficiencia cardíaca (2010) Insuf Card, 5 (2), pp. 51-58 
504 |a Tazar, J., Haurigot, M.P., Caram, R., Haurigot, G.E., Función sistólica del ventrículo derecho en pacientes con hipertensión pulmonar: Análisis con strain y strain rate (2012) Insuf Card, 7 (3), pp. 109-116 
504 |a Lauga, A., D'Ortencio, A., Monitoreo de las presiones de la arteria pulmonar: Catéter de Swan-Ganz. Parte I (2007) Insuf Card, 2 (1), pp. 5-11 
504 |a Launay, D., Sitbon, O., Le Pavec, J., Long-term outcome of systemic sclerosis-associated pulmonary arterial hypertension treated with bosentan as first-line monotherapy followed or not by the addition of prostanoids or sildenafil (2010) Rheumatology (Oxford), 49, pp. 490-500 
504 |a Grignola, J.C., Gómez Sánchez, M.A., Bosentan: Rol en el tratamiento de la hipertensión arterial pulmonar (2009) Insuf Card, 4 (1), pp. 11-22 
504 |a Kaplinsky, E.J., Utilidad del bosentán en la hipertensión pulmonar tromboembólica crónica: Estudio BENEFIT (2008) Insuf Card, 3 (2), pp. 63-64 
504 |a Hoeper, M.M., Markevych, I., Spiekerkoetter, E., Goal-oriented treatment and combination therapy for pulmonary arterial hypertension (2005) Eur Respir J, 26, pp. 858-863 
504 |a Barst, R.J., Miller, D.P., Beery, F., Impact of functional class change on survival in patients with pulmonary arterial hypertension in the REVEAL registry (2011) Am J Respir Crit Care Med, 183, pp. A5941 
504 |a McLaughlin, V.V., Shillington, A., Rich, S., Survival in primary pulmonary hypertension: The impact of epoprostenol therapy (2002) Circulation, 106, pp. 1477-1482 
504 |a Nickel, N., Golpon, H., Greer, M., The prognostic impact of follow-up assessments in patients with idiopathic pulmonary arterial hypertension (2012) Eur Respir J, 39, pp. 589-596 
504 |a Sitbon, O., Humbert, M., Nunes, H., Long-term intravenous epoprostenol infusion in primary pulmonary hypertension: Prognostic factors and survival (2002) J Am Coll Cardiol, 40, pp. 780-788 
504 |a Sitbon, O., Morrell, N.W., Pathways in pulmonary arterial hypertension: The future is here (2012) Eur Respir Rev, 21, pp. 321-327 
504 |a Iglarz, M., Binkert, C., Morrison, K., Pharmacology of macitentan, an orally active tissue-targeting dual endothelin receptor antagonist (2008) J Pharmacol Exp Ther, 327, pp. 736-745 
504 |a Iglarz, M., Landskroner, K., Rey, M., Optimization of tissue targeting properties of macitentan, a new dual endothelin receptor antagonist, improves its efficacy in a rat model of pulmonary fibrosis associated with pulmonary arterial hypertension (2011) Am J Respir Crit Care Med, 183, pp. A6445 
504 |a Raja, S.G., Macitentan, a tissue-targeting endothelin receptor antagonist for the potential oral treatment of pulmonary arterial hypertension and idiopathic pulmonary fibrosis (2010) Curr Opin Investig Drugs, 11, pp. 1066-1073 
504 |a Grimminger, F., Weimann, G., Frey, R., First acute haemodynamic study of soluble guanylate cyclase stimulator riociguat in pulmonary hypertension (2009) Eur Respir J, 33, pp. 785-792 
504 |a Ghofrani, H.A., Morrell, N.W., Hoeper, M.M., Imatinib in pulmonary arterial hypertension patients with inadequate response to established therapy (2010) Am J Respir Crit Care Med, 182, pp. 1171-1177 
504 |a Thierer, J., Importancia del diagnostico precoz en la hipertensión pulmonar (2009) Insuf Card, 4 (2), pp. 52-58 
520 3 |a Over the last decade has witnessed extensive progress in basic and clinical research in the field of pulmonary arterial hypertension (PAH). International PAH registries have achieved much to advance our understanding of the epidemiology, demographics, etiology, clinical course, hemodynamics, disease management and treatment outcomes of PAH. Therapies available to target the pathophysiology of PAH have expanded considerably and more options are expected in the near future. However, the long-term prognosis for patients with PAH remains poor. Recent evidence suggests that World Health Organization functional (WHO) class I or II patients have significantly better long-term survival rates than WHO functional class III-IV patients, thus providing a rationale for earlier diagnosis and treatment of PAH. However, early diagnosis is challenging and there is frequently a delay between symptom onset and diagnosis. Screening programs have an important role in PAH detection and expert opinion favours echocardiographic screening of asymptomatic patients who may be predisposed to the development of PAH. © 2013 Silver Horse.  |l eng 
593 |a División Cardiología, Pabellón Inchauspe, Hospital General de Agudos 'Dr. José María Ramos Mejía', GCBA, Ciudad de Buenos Aires, Argentina 
593 |a Insuficiencia cardíaca, Hipertensión pulmonar, Trasplante cardíaco, Instituto FLENI, Ciudad de Buenos Aires, Argentina 
593 |a Instituto Argentino de Diagnóstico y Tratamiento, Ciudad de Buenos Aires, Argentina 
593 |a Hospital Alta Complejidad en Red El Cruce 'Dr. Néstor Carlos Kirchner', Florencio Varela, Buenos Aires, Argentina 
593 |a Instituto Cardiovascular Lezica, San Isidro, Buenos Aires, Argentina 
593 |a Hospital Italiano de Mendoza, Mendoza, Argentina 
690 1 0 |a EARLY DIAGNOSIS 
690 1 0 |a PULMONARY ARTERIAL HYPERTENSION 
690 1 0 |a SCREENING 
700 1 |a Perrone, S.V. 
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