Contribution of vasoactive intestinal peptide to immune homeostasis in trophoblast-maternal leukocyte interaction under LPS stimulation
Background/Aims: The maternal-fetal interface is a unique immunological site that generates an adequate microenvironment during pregnancy, recognizing and eliminating infections and tolerating the trophoblast/placenta unit. For that purpose, trophoblast cells display several tolerogenic mechanisms t...
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2013
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| LEADER | 17743caa a22017657a 4500 | ||
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| 003 | AR-BaUEN | ||
| 005 | 20230518205555.0 | ||
| 008 | 190411s2013 xx ||||fo|||| 00| 0 eng|d | ||
| 024 | 7 | |2 scopus |a 2-s2.0-84885486812 | |
| 024 | 7 | |2 cas |a nitrite, 14797-65-0; vasoactive intestinal polypeptide, 37221-79-7 | |
| 040 | |a Scopus |b spa |c AR-BaUEN |d AR-BaUEN | ||
| 030 | |a NROIE | ||
| 100 | 1 | |a Fraccaroli, L. | |
| 245 | 1 | 0 | |a Contribution of vasoactive intestinal peptide to immune homeostasis in trophoblast-maternal leukocyte interaction under LPS stimulation |
| 260 | |c 2013 | ||
| 270 | 1 | 0 | |m Laboratory of Immunopharmacology, School of Sciences, University of Buenos Aires, Int. Guiraldes 2160 Piso 4, Buenos Aires C1428EHA, Argentina |
| 506 | |2 openaire |e Política editorial | ||
| 504 | |a Koga, K., Cardenas, I., Aldo, P., Abrahams, V.M., Peng, B., Fill, S., Activation of TLR3 in the trophoblast is associated with preterm delivery (2009) Am J Reprod Immunol, 61, pp. 196-212 | ||
| 504 | |a Koga, K., Paulomi, A., Mor, G., Toll-like receptors and pregnancy: Trophoblast as modulators of the immune response (2009) J Obstest Gynecol Res, 35, pp. 191-202 | ||
| 504 | |a Chaouat, G., Ledee-Bataille, N., Dubanchet, S., Zourbas, S., Sandra, O., Martal, J., Th1/Th2 paradigm in pregnancy: Paradigm lost? Cytokines in pregnancy/early abortion: Reexamining the Th1/Th2 paradigm (2004) International Archives of Allergy and Immunology, 134 (2), pp. 93-119. , DOI 10.1159/000074300 | ||
| 504 | |a Clark, D.A., Chaouat, G., Clark, D.A., Gorczynski, R.M., Thinking outside the box: Mechanisms of environmental selective pressures on the outcome of the materno-fetal relationship (2002) American Journal of Reproductive Immunology, 47 (5), pp. 275-282. , DOI 10.1034/j.1600-0897.2002.01093.x | ||
| 504 | |a Fest, S., Aldo, P.B., Abrahams, V.M., Visintin, I., Alvero, A., Chen, R., Chavez, S.L., Mor, G., Trophoblast-macrophage interactions: A regulatory network for the protection of pregnancy (2007) American Journal of Reproductive Immunology, 57 (1), pp. 55-66. , DOI 10.1111/j.1600-0897.2006.00446.x | ||
| 504 | |a Goldenberg, R.L., Culhane, J.F., Iams, J.D., Romero, R., Epidemiology and causes of preterm birth (2008) Lancet, 5, pp. 75-84 | ||
| 504 | |a Digiulio, D.B., Gervasi, M., Romero, R., Mazaki- Tovi, S., Vaisbuch, E., Kusanovic, J.P., Seok, K.S., Relman, D.A., Microbial invasion of the amniotic cavity in preeclampsia as assessed by cultivation and sequence- based methods (2010) J Perinat Med, 38, pp. 503-513 | ||
| 504 | |a Kim, C.J., Romero, R., Kusanovic, J.P., Yoo, W., Dong, Z., Topping, V., Gotsch, F., Kim, J.S., The frequency, clinical significance, and pathological features of chronic chorioamnionitis: A lesion associated with spontaneous preterm birth (2010) Mod Pathol, 23, pp. 1000-1011 | ||
| 504 | |a Cardenas, I., Means, R., Aldo, P., Koga, K., Lang, L., Booth, C., Manzur, A., Mor, G., Viral infection of the placenta leads to fetal inflammation and sensitization to bacterial products predisposing to preterm labor (2010) J Immunol, 15, pp. 1248-1257 | ||
| 504 | |a Mor, G., Inflammation and pregnancy: The role of toll-like receptors in trophoblast-immune interaction (2008) Annals of the New York Academy of Sciences, 1127, pp. 121-128. , DOI 10.1196/annals.1434.006, Assessment of Human Reproductive Function | ||
| 504 | |a Abrahams, V.M., Bole-Aldo, P., Kim, Y.M., Straszewski-Chavez, S.L., Chaiworapongsa, T., Romero, R., Mor, G., Divergent trophoblast responses to bacterial products mediated by TLRs (2004) Journal of Immunology, 173 (7), pp. 4286-4296 | ||
| 504 | |a Aluvihare, V.R., Kallikourdis, M., Betz, A.G., Regulatory T cells mediate maternal tolerance to the fetus (2004) Nature Immunology, 5 (3), pp. 266-271. , DOI 10.1038/ni1037 | ||
| 504 | |a Larocca, L., Ramhorst, R., Roca, V., Calafat, M., Aisemberg, J., Franchi, A., Perez Leiros, C., Neuroimmune- endocrine interactions during early pregnancy in an autoimmune context: Focus on macrophage activation (2008) Neuroimmunemodulation, 15, pp. 84-90 | ||
| 504 | |a Terness, P., Kallikourdis, M., Betz, A.G., Rabinovich, G.A., Saito, S., Clark, D.A., Tolerance signaling molecules and pregnancy: IDO, galectins, and the renaissance of regulatory T cells (2007) American Journal of Reproductive Immunology, 58 (3), pp. 238-254. , DOI 10.1111/j.1600-0897.2007.00510.x | ||
| 504 | |a Li, J.M., Southerland, L., Hossain, M.S., Giver, C.R., Wang, Y., Darlak, K., Harris, W., Waller, E.K., Absence of vasoactive intestinal peptide expression in hematopoietic cells enhances Th1 polarization and antiviral immunity in mice (2011) J Immunol, 187, pp. 1057-1065 | ||
| 504 | |a Delgado, M., Abad, C., Martinez, C., Leceta, J., Gomariz, R.P., Vasoactive intestinal peptide prevents experimental arthritis by downregulating both autoimmune and inflammatory components of the disease (2001) Nature Medicine, 7 (5), pp. 563-568. , DOI 10.1038/87887 | ||
| 504 | |a Gonzalez-Rey, E., Delgado, M., Vasoactive intestinal peptide and regulatory T-cell induction: A new mechanism and therapeutic potential for immune homeostasis (2007) Trends in Molecular Medicine, 13 (6), pp. 241-251. , DOI 10.1016/j.molmed.2007.04.003, PII S1471491407000676 | ||
| 504 | |a Yadav, M., Goetzl, E.J., Vasoactive intestinal peptide-mediated Th17 differentiation: An expanding spectrum of vasoactive intestinal peptide effects in immunity and autoimmunity (2008) Ann NY Acad Sci, 1144, pp. 83-89 | ||
| 504 | |a Jimeno, R., Gomariz, R.P., Gutierrez-Canas, I., Martinez, C., Juarranz, Y., Leceta, J., New insights into the role of VIP on the ratio of T-cell subsets during the development of autoimmune diabetes (2010) Immunol Cell Biol, 88, pp. 734-745 | ||
| 504 | |a Rosignoli, F., Torroba, M., Juarranz, Y., Gomez, I.A., Martinez, C., Gomariz, R.P., Perez Leiros, C., Leceta, J., VIP and tolerance induction in autoimmunity (2006) Ann NY Acad Sci, 6, pp. 1-6 | ||
| 504 | |a Chorny, A., Gonzalez-Rey, E., Fernandez Martin, A., Ganea, D., Delgado, M., Vasointestinal peptide induces regulatory dendritic cells that prevent acute graft-host disease while maintaining the graft-versus tumor response (2006) Blood, 107, pp. 3787-3794 | ||
| 504 | |a Ekstrom, J., Mansson, B., Tobin, G., Vasoactive intestinal peptide evoked secretion of fluid and protein from rat salivary glands and development of supersensitivity (1983) Acta Physiologica Scandinavica, 119 (2), pp. 169-175 | ||
| 504 | |a Clark, K.E., Mills, E.G., Stys, S.J., Seeds, A.E., Effects of vasoactive polypeptides on the uterine vasculature (1981) American Journal of Obstetrics and Gynecology, 139 (2), pp. 182-188 | ||
| 504 | |a Jovanovic, A., Jovanovic, S., Tulic, I., Grbovic, L., Predominant role for nitric oxide in the relaxation induced by vasoactive intestinal polypeptide in human uterine artery (1998) Molecular Human Reproduction, 4 (1), pp. 71-76. , DOI 10.1093/molehr/4.1.71 | ||
| 504 | |a Roca, V., Calafat, M., Larocca, L., Ramhorst, R., Farina, M., Franchi, A.M., Perez Leiros, C., Potential immunomodulatory role of VIP in the implantation sites of prediabetic nonobese diabetic mice (2009) Reproduction, 138, pp. 733-742 | ||
| 504 | |a Fraccaroli, L., Alfieri, J., Larocca, L., Calafat, M., Roca, V., Lombardi, E., Ramhorst, R., Perez Leiros, C., VIP modulates the pro-inflammatory maternal response inducing tolerance to trophoblast cells (2009) Br J Pharmacol, 156, pp. 116-126 | ||
| 504 | |a Straszewski-Chavez, S.L., Abrahams, V.M., Alvero, A.B., Aldo, P.B., Ma, Y., Guller, S., Romero, R., Mor, G., The isolation and characterization of a novel telomerase immortalized first trimester trophoblast cell line,Swan 71 (2009) Placenta, 30, pp. 939-948 | ||
| 504 | |a Ding, A.H., Nathan, C.F., Stuehr, D.J., Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages: Comparison of activating cytokines and evidence for independent production (1988) J Immunol, 141, pp. 2404-2412 | ||
| 504 | |a Alexander, S.P., Mathie, A., Peters, J.A., Guide to Receptors and Channels (GRAC), 3rd edition (2008) Br J Pharmacol, 153 (SUPPL. 2), pp. S1-S209 | ||
| 504 | |a Ma, Y., Mor, G., Abrahams, V.M., Buhimschi, I.A., Buhimschi, C.S., Guller, S., Alterations in syncytiotrophoblast cytokine expression following treatment with lipopolysaccharide (2006) American Journal of Reproductive Immunology, 55 (1), pp. 12-18. , DOI 10.1111/j.1600-0897.2005.00347.x | ||
| 504 | |a Aisemberg, J., Vercelli, C., Wolfson, M., Salazar, A.I., Osycka-Salut, C., Billi, S., Inflammatory agents involved in septic miscarriage (2010) Neuroimmunomodulation, 17, pp. 150-152 | ||
| 504 | |a Martinez, C., Delgado, M., Abad, C., Gomariz, R.P., Ganea, D., Leceta, J., Regulation of VIP production and secretion by murine lymphocytes (1999) Journal of Neuroimmunology, 93 (1-2), pp. 126-138. , DOI 10.1016/S0165-5728(98)00216-1, PII S0165572898002161 | ||
| 504 | |a Mor, G., Cardenas, I., The immune system in pregnancy: A unique complexity (2010) Am J Reprod Immunol, 63, pp. 425-433 | ||
| 504 | |a Vercelli, C.A., Aisemberg, J., Billi, S., Wolfson, M.L., Franchi, A.M., Endocannabinoid system and nitric oxide are involved in the deleterious effects of lipopolysaccharide on murine decidua (2009) Placenta, 30, pp. 579-584 | ||
| 504 | |a Murphy, S.P., Fast, L.D., Hanna, N.N., Sharma, S., Uterine NK cells mediate inflammation-induced fetal demise in IL-10-null mice (2005) Journal of Immunology, 175 (6), pp. 4084-4090 | ||
| 504 | |a Anton, L., Brown, A., Parry, S., Elovitz, M., Lipopolysaccharide induces cytokine production and decreases extravillous trophoblast invasion through a mitogen-activated protein kinase- mediated pathway: Possible mechanisms of first trimester placental dysfunction (2012) Hum Reprod, 1, pp. 61-72 | ||
| 504 | |a Uh, A., Nicholson, R., Gonzalez, G., Simmons, C., Gombart, A., Smith, R., Equils, O., Lipopolysaccharide (LPS) stimulation of trophoblasts induces corticotrophin-releasing hormone (CRH) expression through MyD88 (2008) Am J Obstet Gynecol, 199 (317), pp. e1-e317. , e6 | ||
| 504 | |a McLean, M., Bistis, A., Davies, J., Woods, R., Lowry, P., Smith, R., A placental clock controlling the length of human pregnancy (1995) Nat Med, 1, pp. 460-463 | ||
| 504 | |a Larocca, L., Calafat, M., Roca, V., Franchi, A.M., Leiros, C.P., VIP limits LPS-induced nitric oxide production through IL-10 in NOD mice macrophages (2007) International Immunopharmacology, 7 (10), pp. 1343-1349. , DOI 10.1016/j.intimp.2007.05.017, PII S1567576907001567 | ||
| 504 | |a Gomariz, R.P., Martinez, C., Abad, C., Leceta, J., Delgado, M., Immunology of VIP: A review and therapeutical perspectives (2001) Current Pharmaceutical Design, 7 (2), pp. 89-111. , DOI 10.2174/1381612013398374 | ||
| 504 | |a Delgado, M., Munoz-Elias, E.J., Gomariz, R.P., Ganea, D., Vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide enhance IL-10 production by murine macrophages: In vitro and in vivo studies (1999) Journal of Immunology, 162 (3), pp. 1707-1716 | ||
| 504 | |a Gonzalez-Rey, E., Anderson, P., Delgado, M., Emerging roles of vasoactive intestinal peptide: A new approach for autoimmune therapy (2007) Ann Rheum Dis, 66, pp. 70-76 | ||
| 504 | |a Mosser, D.M., Edwards, J.P., Exploring the full spectrum of macrophage activation (2008) Nat Rev Immunol, 8, pp. 958-969 | ||
| 504 | |a Rosignoli, F., Torroba, M., Juarranz, Y., Garcia-Gomez, M., Martinez, C., Gomariz, R.P., Perez-Leiros, C., Leceta, J., VIP and tolerance induction in autoimmunity (2006) Annals of the New York Academy of Sciences, 1070, pp. 525-530. , DOI 10.1196/annals.1317.073 | ||
| 504 | |a Larocca, L., Hauk, V., Calafat, M., Roca, V., Fraccaroli, L., Franchi, A., Ramhorst, R., Perez Leiros, C., Modulation of macrophage inflammatory profile in pregnant nonobese diabetic (NOD) mice (2011) Mol Cell Endocrinol, 20, pp. 112-118 | ||
| 504 | |a Weiss, G., Goldsmith, L.T., Taylor, R.N., Bellet, D., Taylor, H.S., Inflammation in reproductive disorders (2009) Reprod Sci, 16, pp. 216-229 | ||
| 504 | |a Paria, B.C., Reese, J., Das, S.K., Dey, S.K., Deciphering the cross-talk of implantation: Advances and challenges (2002) Science, 296 (5576), pp. 2185-2188. , DOI 10.1126/science.1071601 | ||
| 520 | 3 | |a Background/Aims: The maternal-fetal interface is a unique immunological site that generates an adequate microenvironment during pregnancy, recognizing and eliminating infections and tolerating the trophoblast/placenta unit. For that purpose, trophoblast cells display several tolerogenic mechanisms to allow fetal survival, such as production of the neuropeptide vasoactive intestinal peptide (VIP). Here we investigated the contribution of VIP to maintain homeostasis at the maternal-placental interface under lipopolysaccharide (LPS) stimulation. Methods: We performed cocultures between trophoblast cells (Swan-71 cell line) and maternal leukocytes obtained from fertile women as an in vitro model of maternal-placental interaction, and we focused on the effects of LPS on the modulation of VIP and their receptors (VPAC1 and VPAC 2). Results: VIP could prevent the upregulation of IL-6, MCP-1, and nitrite production and maintain the production of IL-10 and TGF-β under LPS (10 μg/ml) stimulation after 48 h of coculture. To gain deeper insight into the mechanisms of how VIP could contribute to a tolerogenic microenvironment even in the presence of LPS, we investigated VIP production by maternal leukocytes and observed a significant increase in the frequency of CD4+VIP+ cells after interaction with Swan-71 cells in the presence of LPS. LPS increased VIP and inducible receptor VPAC2 expression directly on trophoblast cells in a dose- and time-dependent manner. Conclusions: The present results suggest that VIP might act as an additional homeostatic mechanism during early stages at the maternal-placental interface to control exacerbated inflammatory responses such as the ones observed in intrauterine infections. © 2013 S. Karger AG, Basel. |l eng | |
| 593 | |a Laboratory of Immunopharmacology, School of Sciences, University of Buenos Aires, Int. Guiraldes 2160 Piso 4, Buenos Aires C1428EHA, Argentina | ||
| 593 | |a Argentinean Society for Gynecology and Endocrinology Reproduction (SAEGRE), Buenos Aires, Argentina | ||
| 690 | 1 | 0 | |a EARLY PREGNANCY |
| 690 | 1 | 0 | |a HUMAN IMPLANTATION |
| 690 | 1 | 0 | |a TOLERANCE AND PREGNANCY |
| 690 | 1 | 0 | |a VASOACTIVE INTESTINAL PEPTIDE |
| 690 | 1 | 0 | |a INTERLEUKIN 10 |
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| 690 | 1 | 0 | |a LIPOPOLYSACCHARIDE |
| 690 | 1 | 0 | |a MONOCYTE CHEMOTACTIC PROTEIN 1 |
| 690 | 1 | 0 | |a NITRITE |
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| 690 | 1 | 0 | |a VASOACTIVE INTESTINAL POLYPEPTIDE RECEPTOR 2 |
| 690 | 1 | 0 | |a CD14 ANTIGEN |
| 690 | 1 | 0 | |a CD19 ANTIGEN |
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| 690 | 1 | 0 | |a REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION |
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| 700 | 1 | |a Grasso, E. | |
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| 700 | 1 | |a Cortelezzi, M. | |
| 700 | 1 | |a Pérez Leirós, C. | |
| 700 | 1 | |a Ramhorst, R. | |
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