Effect of the organochlorine pesticide endosulfan on GnRH and gonadotrope cell populations in fish larvae
Endocrine-disrupting chemicals can influence the hypothalamus-pituitary- gonad axis and possibly affect reproduction in vertebrates. We analyzed the effect of 30-day endosulfan (ES) exposure in sexually undifferentiated larvae of the cichlid fish Cichlasoma dimerus. The number, area, mean cytoplasmi...
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2011
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| LEADER | 19107caa a22015497a 4500 | ||
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| 001 | PAPER-23645 | ||
| 003 | AR-BaUEN | ||
| 005 | 20230518205522.0 | ||
| 008 | 190411s2011 xx ||||fo|||| 00| 0 eng|d | ||
| 024 | 7 | |2 scopus |a 2-s2.0-79960443749 | |
| 024 | 7 | |2 cas |a endosulfan, 115-29-7; gonadorelin, 33515-09-2, 9034-40-6; Endosulfan, 115-29-7; Follicle Stimulating Hormone, 9002-68-0; Gonadotropin-Releasing Hormone, 33515-09-2; Hydrocarbons, Chlorinated; Insecticides | |
| 040 | |a Scopus |b spa |c AR-BaUEN |d AR-BaUEN | ||
| 030 | |a AECTC | ||
| 100 | 1 | |a Piazza, Y.G. | |
| 245 | 1 | 0 | |a Effect of the organochlorine pesticide endosulfan on GnRH and gonadotrope cell populations in fish larvae |
| 260 | |c 2011 | ||
| 270 | 1 | 0 | |m Lo Nostro, F.L.; Department of Biodiversity and Experimental Biology, Faculty of Exact and Natural Sciences, University of Buenos Aires, Buenos Aires C1428EHA, Argentina; email: fabi@bg.fcen.uba.ar |
| 506 | |2 openaire |e Política editorial | ||
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| 520 | 3 | |a Endocrine-disrupting chemicals can influence the hypothalamus-pituitary- gonad axis and possibly affect reproduction in vertebrates. We analyzed the effect of 30-day endosulfan (ES) exposure in sexually undifferentiated larvae of the cichlid fish Cichlasoma dimerus. The number, area, mean cytoplasmic and nuclear diameter, and mean cytoplasmic optical density of gonadotropin-releasing hormone (GnRH) I, II, and III immunoreactive (ir-) neurons and β follicle-stimulating hormone (βFSH) ir-cells were measured. Animals exposed to the highest ES concentration (0.1 μg/l) showed a decrease in GnRH I nucleus/cytoplasm area ratio upon exposure. Nuclear area and mean nuclear diameter of βFSH ir-cells was higher in ES treated fish. βFSH nucleus/cytoplasm area ratio was high in exposed animals, and animals exposed to 0.1 μg/l ES showed smaller mean cytoplasmic optical density. These findings suggest that ES affects GnRH I and βFSH protein synthesis/release. However, these responses seem to be insufficient to affect gonadal differentiation at this stage of development. © 2010 Springer Science+Business Media, LLC. |l eng | |
| 593 | |a Department of Biodiversity and Experimental Biology, Faculty of Exact and Natural Sciences, University of Buenos Aires, Buenos Aires C1428EHA, Argentina | ||
| 593 | |a National Council of Scientific and Technical Research (CONICET), Buenos Aires C1033AAJ, Argentina | ||
| 690 | 1 | 0 | |a ENDOSULFAN |
| 690 | 1 | 0 | |a FOLLITROPIN BETA SUBUNIT |
| 690 | 1 | 0 | |a GONADORELIN |
| 690 | 1 | 0 | |a CELL ORGANELLE |
| 690 | 1 | 0 | |a CONCENTRATION (COMPOSITION) |
| 690 | 1 | 0 | |a DEVELOPMENTAL BIOLOGY |
| 690 | 1 | 0 | |a DIAMETER |
| 690 | 1 | 0 | |a ENDOCRINE DISRUPTOR |
| 690 | 1 | 0 | |a ENDOSULFAN |
| 690 | 1 | 0 | |a FISH |
| 690 | 1 | 0 | |a FUNCTIONAL MORPHOLOGY |
| 690 | 1 | 0 | |a HORMONE |
| 690 | 1 | 0 | |a LARVA |
| 690 | 1 | 0 | |a ORGANOCHLORINE |
| 690 | 1 | 0 | |a PHYSIOLOGICAL RESPONSE |
| 690 | 1 | 0 | |a POLLUTION EXPOSURE |
| 690 | 1 | 0 | |a POPULATION STRUCTURE |
| 690 | 1 | 0 | |a REPRODUCTION |
| 690 | 1 | 0 | |a ARTICLE |
| 690 | 1 | 0 | |a CELL POPULATION |
| 690 | 1 | 0 | |a CICHLASOMA DIMERUS |
| 690 | 1 | 0 | |a CICHLID |
| 690 | 1 | 0 | |a CONTROLLED STUDY |
| 690 | 1 | 0 | |a CYTOPLASM |
| 690 | 1 | 0 | |a GONAD DEVELOPMENT |
| 690 | 1 | 0 | |a LARVA |
| 690 | 1 | 0 | |a NONHUMAN |
| 690 | 1 | 0 | |a NUCLEUS ACCUMBENS |
| 690 | 1 | 0 | |a OPTICAL DENSITY |
| 690 | 1 | 0 | |a PRIORITY JOURNAL |
| 690 | 1 | 0 | |a PROTEIN SECRETION |
| 690 | 1 | 0 | |a PROTEIN SYNTHESIS |
| 690 | 1 | 0 | |a ANIMALS |
| 690 | 1 | 0 | |a CICHLIDS |
| 690 | 1 | 0 | |a ENDOSULFAN |
| 690 | 1 | 0 | |a ENVIRONMENTAL EXPOSURE |
| 690 | 1 | 0 | |a FOLLICLE STIMULATING HORMONE |
| 690 | 1 | 0 | |a GONADOTROPHS |
| 690 | 1 | 0 | |a GONADOTROPIN-RELEASING HORMONE |
| 690 | 1 | 0 | |a GONADS |
| 690 | 1 | 0 | |a HYDROCARBONS, CHLORINATED |
| 690 | 1 | 0 | |a INSECTICIDES |
| 690 | 1 | 0 | |a LARVA |
| 690 | 1 | 0 | |a NEURONS |
| 690 | 1 | 0 | |a ANIMALIA |
| 690 | 1 | 0 | |a CICHLASOMA |
| 690 | 1 | 0 | |a CICHLIDAE |
| 690 | 1 | 0 | |a VERTEBRATA |
| 700 | 1 | |a Pandolfi, M. | |
| 700 | 1 | |a Lo Nostro, F.L. | |
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