Trans-sialidase and mucins of Trypanosoma cruzi: An important interplay for the parasite
A dense glycocalix covers the surface of Trypanosoma cruzi, the agent of Chagas disease. Sialic acid in the surface of the parasite plays an important role in the infectious process, however, T. cruzi is unable to synthesize sialic acid or the usual donor CMP-sialic acid. Instead, T. cruzi expresses...
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2011
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| Acceso en línea: | Registro en Scopus DOI Handle Registro en la Biblioteca Digital |
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| LEADER | 14002caa a22017897a 4500 | ||
|---|---|---|---|
| 001 | PAPER-23624 | ||
| 003 | AR-BaUEN | ||
| 005 | 20230518205520.0 | ||
| 008 | 190411s2011 xx ||||fo|||| 00| 0 eng|d | ||
| 024 | 7 | |2 scopus |a 2-s2.0-79959930795 | |
| 024 | 7 | |2 cas |a sialidase, 9001-67-6; Enzyme Inhibitors; Glycoconjugates; Glycoproteins; Glycosylphosphatidylinositols; Mucins; Neuraminidase, 3.2.1.18; Sialic Acids; Type C Phospholipases, 3.1.4.-; trans-sialidase, 3.2.1.- | |
| 040 | |a Scopus |b spa |c AR-BaUEN |d AR-BaUEN | ||
| 030 | |a CRBRA | ||
| 100 | 1 | |a Eugenia Giorgi, M. | |
| 245 | 1 | 0 | |a Trans-sialidase and mucins of Trypanosoma cruzi: An important interplay for the parasite |
| 260 | |c 2011 | ||
| 270 | 1 | 0 | |m De Lederkremer, R.M.; CIHIDECAR, Departamento de Química Orgánica, Ciudad Universitaria, Pabellón II, 1428 Buenos Aires, Argentina; email: lederk@qo.fcen.uba.ar |
| 506 | |2 openaire |e Política editorial | ||
| 504 | |a Brener, Z., (1973) Ann. Rev. Microbiol., 27, pp. 347-382 | ||
| 504 | |a Moncayo, A., (2003) Mem. Inst. Oswaldo Cruz., 98, pp. 577-591 | ||
| 504 | |a Anonymous, (1999) Mem. Inst. Oswaldo Cruz., 429, p. 432 | ||
| 504 | |a Zingales, B., Andrade, S.G., Briones, M.R., Campbell, D.A., Chiari, E., Fernandes, O., Guhl, F., Schijman, A.G., (2009) Mem. Inst. Oswaldo Cruz., 104, pp. 1051-1054 | ||
| 504 | |a Lederkremer, R.M., Agustí, R., (2009) Adv. Carbohydr. Chem. Biochem., 62, pp. 311-366 | ||
| 504 | |a Lederkremer, R.M., Bertello, L.E., (2001) Curr. Pharm. Des., 7, pp. 1165-1179 | ||
| 504 | |a Previato, J.O., Wait, R., Jones, C., Dosreis, G.A., Todeschini, A.R., Heise, N., Previato, L.M., (2004) Adv. Parasitol., 56, pp. 1-41 | ||
| 504 | |a Schenkman, S., Jiang, M.S., Hart, G.W., Nussenzweig, V., (1991) Cell, 65, pp. 1117-1125 | ||
| 504 | |a Frasch, A.C.C., (2000) Parasitol. Today, 16, pp. 282-286 | ||
| 504 | |a Ferrero-Garcia, M.A., Trombetta, S.E., Sanchez, D.O., Reglero, A., Frasch, A.C.C., Parodi, A.J., (1993) Eur. J. Biochem., 213, pp. 765-771 | ||
| 504 | |a Schenkman, S., Eichinger, D., Pereira, M.E., Nussenzweig, V., (1994) Annu. Rev. Microbiol., 48, pp. 499-523 | ||
| 504 | |a Buschiazzo, A., Alzari, P.M., (2008) Curr. Opin. Chem. Biol., 12, pp. 565-572 | ||
| 504 | |a Agusti, R., Giorgi, M.E., Lederkremer, R.M., (2007) Carbohydr. Res., 342, pp. 2465-2469 | ||
| 504 | |a Schroven, A., Meinke, S., Ziegelmuller, P., Thiem, J., (2007) Chem. Eur. J., 13, pp. 9012-9021 | ||
| 504 | |a Zingales, B., Carniol, C., Lederkremer, R.M., Colli, W., (1987) Mol. Biochem. Parasitol., 26, pp. 135-144 | ||
| 504 | |a Chaves, L.B., Briones, M.R., Schenkman, S., (1993) Mol. Biochem. Parasitol., 61, pp. 97-106 | ||
| 504 | |a Amino, R., Acosta-Serrano, A., Morita, O.M., Pereira-Chioccola, V.L., Schenkman, S., (1995) Glycobiology, 5, pp. 625-631 | ||
| 504 | |a Buschiazzo, A., Frasch, A.C.C., Campetella, O., (1996) Cell. Mol. Biol., 42, pp. 703-710 | ||
| 504 | |a Paris, G., Cremona, M.L., Amaya, M.F., Buschiazzo, A., Giambiagi, S., Frasch, A.C.C., Alzari, P.M., (2001) Glycobiology, 11, pp. 305-311 | ||
| 504 | |a Agusti, R., Paris, G., Ratier, L., Frasch, A.C.C., Lederkremer, R.M., (2004) Glycobiology, 14, pp. 659-670 | ||
| 504 | |a Buschiazzo, A., Amaya, M.F., Cremona, M.L., Frasch, A.C.C., Alzari, P.M., (2002) Mol. Cell, 10, pp. 575-768 | ||
| 504 | |a Amaya, M.F., Buschiazzo, A., Nguyen, T., Alzari, P.M., (2003) J. Mol. Biol., 325, pp. 773-784 | ||
| 504 | |a Amaya, M.F., Watts, A.G., Damager, I., Wehenkel, A., Nguyen, T., Buschiazzo, A., Paris, G., Alzari, P.M., (2004) Structure, 12, pp. 775-784 | ||
| 504 | |a Todeschini, A.R., Dias, W.B., Girard, M.F., Wieruszeski, J.M., Mendona-Previato, L., Previato, J.O., (2004) J. Biol. Chem., 279, pp. 5323-5328 | ||
| 504 | |a Magdesian, M.H., Tonelli, R.R., Fessel, M.R., Silveira, M.S., Schumacher, R.I., Linden, R., Colli, W., Alves, M.J., (2006) Exp. Cell Res., 313, pp. 210-218 | ||
| 504 | |a Tonelli, R.R., Giordano, R.J., Barbu, E.M., Torrecilhas, A.C., Kobayashi, G.S., Langley, R.R., Arap, W., Alves, M.J., (2010) PloS Negl. Trop. Dis., 4, p. 864 | ||
| 504 | |a Santos, M.A., Garg, N., Tarleton, R.L., (1997) Mol. Biochem. Parasitol., 86, pp. 1-11 | ||
| 504 | |a Agusti, R., Couto, A.S., Campetella, O., Frasch, A.C.C., Lederkremer, R.M., (1997) Glycobiology, 7, pp. 731-735 | ||
| 504 | |a Agusti, R., Couto, A.S., Campetella, O., Frasch, A.C.C., Lederkremer, R.M., (1998) Mol. Biochem. Parasitol., 97, pp. 123-131 | ||
| 504 | |a Leguizamón, M.S., Mocetti, E., Garcia Rivello, H., Argibay, P., Campetella, O., (1999) J. Infect. Dis., 180, pp. 1398-1402 | ||
| 504 | |a Risso, M.G., Pitcovsky, T.A., Caccuri, R.L., Campetella, O., Leguizamón, M.S., (2007) Parasitology, 134, pp. 503-510 | ||
| 504 | |a Mucci, J., Hidalgo, A., Mocetti, E., Argibay, P.F., Leguizamón, M.S., Campetella, O., (2002) Proc. Natl. Acad. Sci. USA, 99, pp. 3896-3901 | ||
| 504 | |a Mucci, J., Mocetti, E., Leguizamón, M.S., Campetella, O., (2005) J. Immunol., 174, pp. 4545-4550 | ||
| 504 | |a Mucci, J., Risso, M.G., Leguizamón, M.S., Frasch, A.C., Campetell, O., (2006) Cell. Microbiol., 8, pp. 1086-1095 | ||
| 504 | |a Rubin-De-Celis, S.S., Uemura, H., Yoshida, N., Schenkman, S., (2006) Cell. Microbiol., 8, pp. 1888-1898 | ||
| 504 | |a Risso, M.G., Garbarino, G.B., Mocetti, E., Campetella, O., Gonzalez Cappa, S.M., Buscaglia, C.A., Leguizamon, M.S., (2004) J. Infect. Dis., 189, pp. 2250-2259 | ||
| 504 | |a Erdmann, H., Steeg, C., Koch-Nolte, F., Fleischer, B., Jacobs, T., (2009) Cell. Microbiol., 11, pp. 1600-1611 | ||
| 504 | |a Jacobs, T., Erdmann, H., Fleischer, B., (2010) Eur. J. Cell Biol., 89, pp. 113-116 | ||
| 504 | |a Muiá, R.P., Yu, H., Prescher, J.A., Hellman, U., Chen, X., Bertozzi, C.R., Campetella, O., (2010) Glycobiology, 20, pp. 833-842 | ||
| 504 | |a Neres, J., Bryce, R.J., Douglas, K.T., (2008) Drug Discovery Today, 13, pp. 110-117 | ||
| 504 | |a Buchini, S., Buschiazzo, A., Withers, S.G., (2008) Angew. Chem., Int. Ed., 47, pp. 2700-2703 | ||
| 504 | |a Carvalho, S.T., Sola-Penna, M., Oliveira, I.A., Pita, S., Gonalves, A.S., Neves, B.C., Sousa, F.R., Todeschini, A.R., (2010) Glycobiology, 20, pp. 1034-1045 | ||
| 504 | |a Kim, J.H., Ryu, H.W., Shim, J.H., Park, K.H., Withers, S.G., (2009) Chembiochem, 10, p. 2475 | ||
| 504 | |a Arioka, S., Sakagami, M., Uematsu, R., Yamaguchi, H., Togame, H., Takemoto, H., Hinou, H., Nishimura, S., (2010) Bioorg. Med. Chem., 18, p. 1633 | ||
| 504 | |a Giorgi, M.E., Ratier, L., Agusti, R., Frasch, A.C.C., Lederkremer, R.M., (2010) Glycoconjugate J., 27, pp. 549-559 | ||
| 504 | |a Buscaglia, A.C., Campo, V.A., Frasch, A.C.C., Di Noia, J.M., (2006) Nat. Rev. Microbiol., 4, pp. 229-236 | ||
| 504 | |a Pereira-Chioccola, V.L., Acosta-Serrano, A., Correira De Almeida, I., Ferguson, M.A.J., Souto-Padron, T., Rodrigues, M.M., Travassos, L.R., Schenkman, S., (2000) J. Cell Sci., 113, pp. 1299-1307 | ||
| 504 | |a Almeida, I.C., Ferguson, M.A.J., Schenkman, S., Travassos, L.R., (1994) Biochem. J., 304, pp. 793-802 | ||
| 504 | |a Couto, A.S., Gonalves, M.F., Colli, W., Lederkremer, R.M., (1990) Mol. Biochem. Parasitol., 39, pp. 101-107 | ||
| 504 | |a Acosta-Serrano, A., Schenkman, S., Yoshida, N., Mehlert, A., Richardson, J., Ferguson, M.A.J., (1995) J. Biol. Chem., 270, pp. 27244-27253 | ||
| 504 | |a Previato, J.O., Jones, C., Gonalves, L.B.P., Wait, R., Travassos, L.R., Mendona-Previato, L., (1994) Biochem. J., 301, pp. 151-159 | ||
| 504 | |a Agrellos, O.A., Jones, C., Todeschini, A.R., Previato, J.O., Mendona-Previato, L., (2003) Mol. Biochem. Parasitol., 126, pp. 93-96 | ||
| 504 | |a Todeschini, A.R., Almeida, E.G., Agrellos, O.A., Jones, C., Previato, J.O., Mendona-Previato, L., (2009) Mem. Inst. Oswaldo Cruz., 104, pp. 270-274 | ||
| 504 | |a Previato, J.O., Jones, C., Gonalves, P.B., Wait, R., Travassos, L.R., Parodi, A.J., Mendona-Previato, L., (1995) J. Biol. Chem., 270, pp. 7241-7250 | ||
| 504 | |a Salto, M.L., Gallo-Rodriguez, C., Lima, C., Lederkremer, R.M., (2000) Anal. Biochem., 279, pp. 79-84 | ||
| 504 | |a Pollevick, G.D., Di Noia, J.M., Salto, M.L., Lima, C., Leguizamon, M.S., Lederkremer, R.M., Frasch, A.C.C., (2000) J. Biol. Chem., 275, pp. 27671-27680 | ||
| 504 | |a Todeschini, A.R., Da Silveira, E.X., Jones, C., Wait, R., Previato, J.O., Mendona-Previato, L., (2001) Glycobiology, 11, pp. 47-55 | ||
| 504 | |a Jones, C., Todeschini, A.R., Agrellos, O.A., Previato, J.O., Mendona-Previato, L., (2004) Biochemistry, 43, pp. 11889-11897 | ||
| 504 | |a De Arruda, M.V., Colli, W., Zingales, B., (1989) Eur. J. Biochem., 182, pp. 413-421 | ||
| 504 | |a Tetaud, E., Barret, M.P., Bringaud, F., Baltz, T., (1997) Biochem. J., 325, pp. 569-580 | ||
| 504 | |a Roper, J.R., Ferguson, M.A.J., (2003) Mol. Biochem. Parasitol., 132, pp. 47-53 | ||
| 504 | |a Beverley, S.M., Owens, K.L., Showalter, M., Griffith, C.L., Doering, T.L., Jones, V.C., Mc Neil, M.R., (2005) Eukariot. Cell, 4, pp. 1147-1154 | ||
| 504 | |a Bakker, H., Kleczka, B., Gerardy-Schahn, R., Routier, F.H., (2005) Biol. Chem., 386, pp. 657-661 | ||
| 504 | |a Previato, J.O., Sola-Penna, M., Agrellos, O.A., Jones, C., Oekmann, T., Travassos, L.R., Mendona-Previato, L., (1998) J. Biol. Chem., 273, pp. 14982-14988 | ||
| 504 | |a Campo, V.A., Buscaglia, C.A., Di Noia, J.M., Frasch, A.C.C., (2006) Microbes Infect., 2, pp. 401-409 | ||
| 504 | |a Mendoza, V.M., Kashiwagi, G.A., Lederkremer, R.M., Gallo-Rodriguez, C., (2010) Carbohydr. Res., 345, pp. 385-396 | ||
| 504 | |a Mendoza, V.M., Agusti, R., Gallo-Rodriguez, C., Lederkremer, R.M., (2006) Carbohydr. Res., 341, pp. 1488-1497 | ||
| 504 | |a Agusti, R., Giorgi, M.E., Mendoza, V.M., Gallo-Rodriguez, C., Lederkremer, R.M., (2007) Bioorg. Med. Chem., 15, pp. 2611-2617 | ||
| 520 | 3 | |a A dense glycocalix covers the surface of Trypanosoma cruzi, the agent of Chagas disease. Sialic acid in the surface of the parasite plays an important role in the infectious process, however, T. cruzi is unable to synthesize sialic acid or the usual donor CMP-sialic acid. Instead, T. cruzi expresses a unique enzyme, the trans-sialidase (TcTS) involved in the transfer of sialic acid from host glycoconjugates to mucins of the parasite. The mucins are the major glycoproteins in the insect stage epimastigotes and in the infective trypomastigotes. Both, the mucins and the TcTS are anchored to the plasma membrane by a glycosylphosphatidylinositol anchor. Thus, TcTS may be shed into the bloodstream of the mammal host by the action of a parasite phosphatidylinositol-phospholipase C, affecting the immune system. The composition and structure of the sugars in the parasite mucins is characteristic of each differentiation stage, also, interstrain variations were described for epimastigote mucins. This review focus on the characteristics of the interplay between the trans-sialidase and the mucins of T. cruzi and summarizes the known carbohydrate structures of the mucins. © 2011 Elsevier Ltd. All rights reserved. |l eng | |
| 536 | |a Detalles de la financiación: Agencia Nacional de Promoción Científica y Tecnológica | ||
| 536 | |a Detalles de la financiación: Universidad de Buenos Aires | ||
| 536 | |a Detalles de la financiación: We thank grants from Agencia Nacional de Promoción Científica y Tecnológica (ANPCyT) and Universidad de Buenos Aires, Argentina. R. M. de Lederkremer is a research member of CONICET. | ||
| 593 | |a CIHIDECAR, Departamento de Química Orgánica, Ciudad Universitaria, Pabellón II, 1428 Buenos Aires, Argentina | ||
| 690 | 1 | 0 | |a CHAGAS DISEASE |
| 690 | 1 | 0 | |a MUCINS |
| 690 | 1 | 0 | |a TRANS-SIALIDASE |
| 690 | 1 | 0 | |a TRYPANOSOMA CRUZI |
| 690 | 1 | 0 | |a CHAGAS DISEASE |
| 690 | 1 | 0 | |a EPIMASTIGOTES |
| 690 | 1 | 0 | |a GLYCOCONJUGATES |
| 690 | 1 | 0 | |a GLYCOSYLPHOSPHATIDYLINOSITOL ANCHORS |
| 690 | 1 | 0 | |a IMMUNE SYSTEMS |
| 690 | 1 | 0 | |a MUCINS |
| 690 | 1 | 0 | |a PARASITE- |
| 690 | 1 | 0 | |a SIALIC ACIDS |
| 690 | 1 | 0 | |a TRANS-SIALIDASES |
| 690 | 1 | 0 | |a TRYPANOSOMA CRUZI |
| 690 | 1 | 0 | |a CELL MEMBRANES |
| 690 | 1 | 0 | |a SUGARS |
| 690 | 1 | 0 | |a CARBOXYLIC ACIDS |
| 690 | 1 | 0 | |a GLYCOCONJUGATE |
| 690 | 1 | 0 | |a GLYCOSYLPHOSPHATIDYLINOSITOL |
| 690 | 1 | 0 | |a MUCIN |
| 690 | 1 | 0 | |a OLIGOSACCHARIDE |
| 690 | 1 | 0 | |a SIALIDASE |
| 690 | 1 | 0 | |a ARTICLE |
| 690 | 1 | 0 | |a CARBOHYDRATE ANALYSIS |
| 690 | 1 | 0 | |a ENZYME ACTIVITY |
| 690 | 1 | 0 | |a EPIMASTIGOTE |
| 690 | 1 | 0 | |a NONHUMAN |
| 690 | 1 | 0 | |a PRIORITY JOURNAL |
| 690 | 1 | 0 | |a SIALYLATION |
| 690 | 1 | 0 | |a TRYPANOSOMA CRUZI |
| 690 | 1 | 0 | |a TRYPOMASTIGOTE |
| 690 | 1 | 0 | |a ANIMALS |
| 690 | 1 | 0 | |a CARBOHYDRATE SEQUENCE |
| 690 | 1 | 0 | |a CHAGAS DISEASE |
| 690 | 1 | 0 | |a ENZYME INHIBITORS |
| 690 | 1 | 0 | |a GLYCOCONJUGATES |
| 690 | 1 | 0 | |a GLYCOPROTEINS |
| 690 | 1 | 0 | |a GLYCOSYLPHOSPHATIDYLINOSITOLS |
| 690 | 1 | 0 | |a HUMANS |
| 690 | 1 | 0 | |a LIFE CYCLE STAGES |
| 690 | 1 | 0 | |a MOLECULAR SEQUENCE DATA |
| 690 | 1 | 0 | |a MUCINS |
| 690 | 1 | 0 | |a NEURAMINIDASE |
| 690 | 1 | 0 | |a PROTEIN BINDING |
| 690 | 1 | 0 | |a SIALIC ACIDS |
| 690 | 1 | 0 | |a SPECIES SPECIFICITY |
| 690 | 1 | 0 | |a TRYPANOSOMA CRUZI |
| 690 | 1 | 0 | |a TYPE C PHOSPHOLIPASES |
| 690 | 1 | 0 | |a HEXAPODA |
| 690 | 1 | 0 | |a MAMMALIA |
| 690 | 1 | 0 | |a TRYPANOSOMA CRUZI |
| 700 | 1 | |a De Lederkremer, R.M. | |
| 773 | 0 | |d 2011 |g v. 346 |h pp. 1389-1393 |k n. 12 |p Carbohydr. Res. |x 00086215 |w (AR-BaUEN)CENRE-301 |t Carbohydrate Research | |
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