Antioxidant and cardioprotective effects of Ilex brasiliensis: A comparative study with Ilex paraguariensis (yerba mate)

Our objective was to compare the antioxidant properties and cardiovascular effects in ischemia-reperfusion of leaves aqueous extracts of Ilex brasiliensis (B) and Ilex paraguariensis (P). In vitro systems were used to assess the antioxidant properties of the extracts. Isolated rat hearts were treate...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autor principal: Schinella, G.
Otros Autores: Fantinelli, J.C, Tournier, H., Prieto, J.M, Spegazzini, E., Debenedetti, S., Mosca, S.M
Formato: Capítulo de libro
Lenguaje:Inglés
Publicado: 2009
Acceso en línea:Registro en Scopus
DOI
Handle
Registro en la Biblioteca Digital
Aporte de:Registro referencial: Solicitar el recurso aquí
LEADER 11106caa a22010577a 4500
001 PAPER-23034
003 AR-BaUEN
005 20230518205440.0
008 190411s2009 xx ||||fo|||| 00| 0 eng|d
024 7 |2 scopus  |a 2-s2.0-70349761234 
040 |a Scopus  |b spa  |c AR-BaUEN  |d AR-BaUEN 
030 |a FORIE 
100 1 |a Schinella, G. 
245 1 0 |a Antioxidant and cardioprotective effects of Ilex brasiliensis: A comparative study with Ilex paraguariensis (yerba mate) 
260 |c 2009 
270 1 0 |m Mosca, S.M.; Centro de Investigaciones Cardiovasculares, Universidad Nacional de La Plata-CONICET, La Plata, Buenos Aires, Argentina; email: smosca@atlas.med.unlp.edu.ar 
506 |2 openaire  |e Política editorial 
504 |a Aruoma, O.I., Bahorun, T., Jen, L.S., Neuroprotection by bioactive components in medicinal and food plant extracts (2003) Mutation Research, 544, pp. 203-215 
504 |a Balavoine, G.G., Geletii, Y.V., Peroxynitrite scavenging by different antioxidants. Part I: Convenient assay (1999) Nitric Oxide, 3, pp. 40-54 
504 |a Benzie, I.F.F., Strain, J.J., The ferric reducing ability of plasma (FRAP) as a measure of "antioxidant power": The FRAP assay (1996) Analytical Biochemistry, 239, pp. 70-76 
504 |a Bixby, M., Spieler, L., Menini, T., Gugliucci, A., Ilex paraguariensis extracts are potent inhibitors of nitrosative stress: A comparative study with green tea and wines using a protein nitration model and mammalian cell cytotoxicity (2005) Life Sciences, 77, pp. 345-358 
504 |a Bolli, R., Causative role of oxyradicals in myocardial stunning: A proven hypothesis. A brief review of the evidence demonstrating a major role of reactive oxygen species in several forms of postischemic dysfunction (1998) Basic Research in Cardiology, 93, pp. 156-162 
504 |a Bolli, R., Cardioprotective function of inducible nitric oxide synthase and role of nitric oxide in myocardial ischemia and preconditioning: An overview of a decade of research (2001) Journal Molecular & Cellular Cardiology, 33, pp. 1897-1918 
504 |a Braunwald, E., Kloner, R.A., The stunned myocardium: Prolonged, post-ischemic ventricular dysfunction (1982) Circulation, 66, pp. 1146-1149 
504 |a Burkitt, M.J., Gilbert, B.C., Model studies of the iron-catalysed Haber-Weiss cycle and the ascorbate-driven Fenton reaction (1990) Free Radical Research Communications, 10 (4-5), pp. 265-280 
504 |a Cai, H., Harrison, D.G., Endothelial dysfunction in cardiovascular diseases: The role of oxidant stress (2000) Circulation Research, 87, pp. 840-844 
504 |a Choi, Y.H., Sertic, S., Kim, H.K., Wilson, E.G., Michopoulos, F., Lefeber, A.W., Classification of Ilex species based on metabolomic fingerprinting using nuclear magnetic resonance and multivariate data analysis (2005) Journal of Agricultural & Food Chemistry, 53 (4), pp. 1237-1245 
504 |a Filip, R., Ferraro, G.E., Researching on new species of "Mate": Ilex brevicuspis: Phytochemical and pharmacology study (2003) European Journal of Nutrition, 42, pp. 50-54 
504 |a Filip, R., Lotito, S.B., Ferraro, G., Fraga, C.G., Antioxidant activity of Ilex paraguariensis and related species (2000) Nutrition Research, 20, pp. 1437-1446 
504 |a Frei, B., Stocker, R., Ames, B.N., Antioxidant defenses and lipid peroxidation in human blood plasma (1988) Proceedings of the National Academy of Sciences USA, 85, pp. 9748-9752 
504 |a Giner, R.M., Recio, M.C., Cuellar, M.J., Máñez, S., Peris, J.B., Stübing, G., A taxonomical study of the subtribe Leontodontinae based on the distribution of phenolic compounds (1993) Biochemical Systematics & Ecology, 21, pp. 613-616 
504 |a Góngora, L., Giner, R.M., Máñez, S., Recio, M.d.C., Ríos, J.L., Phagnalon rupestre as a source of compounds active on contact hypersensitivity (2002) Planta Medica, 68 (6), pp. 561-564 
504 |a Gorgen, M., Turatti, K., Medeiros, A.R., Buffon, A., Bonan, C.D., Sarkis, J.J., Aqueous extract of Ilex paraguariensis decreases nucleotide hydrolysis in rat blood serum (2005) Journal of Ethnopharmacology, 97, pp. 73-77 
504 |a Gugliucci, A., Antioxidant effects of Ilex paraguariensis: Induction of decreased oxidability of human LDL in vivo (1996) Biochemical & Biophysical Research Communications, 224, pp. 338-344 
504 |a Jiao, K., Mandapati, S., Skipper, P.L., Tannenbaum, S.R., Wishnok, J.S., Site-selective nitration of tyrosine in human serum albumin by peroxynitrite (2001) Analytical Biochemistry, 293 (1), pp. 43-52 
504 |a Kim, J.S., Ohshima, S., Pediaditakis, P., Lemasters, J.J., Nitric oxide: A signaling molecule against mitochondrial permeability transition- and pH-dependent cell death after reperfusion (2004) Free Radical Biology & Medicine, 37, pp. 1943-1950 
504 |a Kodja, G., Harrison, D., Interactions between NO and reactive oxygen species: Pathophysiological importance in atherosclerosis, hypertension, diabetes and heart failure (1999) Cardiovascular Research, 43, pp. 562-571 
504 |a Mellin, V., Isabelle, M., Oudot, A., Vergely-Vandriesse, C., Monteil, C., Di Meglio, B., Transient reduction in myocardial free oxygen radical levels is involved in the improved cardiac function and structure after long-term allopurinol treatment initiated in established chronic heart failure (2005) European Heart Journal, 26, pp. 1544-1550 
504 |a Re, R., Pellegrini, N., Proteggente, A., Pannala, A., Yang, M., Rice-Evans, C., Antioxidant activity applying an improved ABTS radical cation decolonization assay (1999) Free Radical Biology & Medicine, 26, pp. 1231-1237 
504 |a Riksen, N.P., Zhou, Z., Oyen, W.J.G., Jaspers, R., Ramakers, B.P., Brouwer, R.M.H.J., Caffeine prevents protection in two human models of ischemic preconditioning (2006) Journal of the American College of Cardiology, 48, pp. 700-707 
504 |a Schinella, G., Fantinelli, J.C., Mosca, S.M., Cardioprotective effects of Ilex paraguariensis extract: Evidence for a nitric oxide dependent mechanism (2005) Clinical Nutrition, 24, pp. 360-366 
504 |a Schinella, G.R., Tournier, H.A., Mánez, S., de Buschiazzo, P.M., Del Carmen Recio, M., Rios, J.L., Tiliroside and gnaphaliin inhibit human low density lipoprotein oxidation (2007) Fitoterapia, 78, pp. 1-6 
504 |a Schinella, G., Troiani, G., Dávila, V., de Buschiazzo, P.M., Tournier, H.A., Antioxidant effects of an aqueous extract of Ilex paraguariensis (2000) Biochemical & Biophysical Research Communications, 269, pp. 357-360 
504 |a Sedlak, J., Lindsay, R.H., Estimation of total, protein-bound, and nonprotein sulfhydryl groups in tissue with Ellman's reagent (1968) Analytical Biochemistry, 25, pp. 192-205 
504 |a Squadrito, G.L., Jin, X., Pryor, W.A., Stopped-flow kinetic study of the reaction of ascorbic acid with peroxynitrite (1995) Archives of Biochemistry & Biophysics, 322 (1), pp. 53-59 
504 |a Steenbergen, C., Murphy, E., Watts, J.A., London, R.E., Correlation between cytosolic free calcium, contracture, ATP, and irreversible ischemic injury in perfused rat heart (1990) Circulation Research, 66, pp. 135-146 
504 |a Tavazzi, B., Di Pierro, D., Bartolini, M., Marino, M., Distefano, S., Galvano, M., Lipid peroxidation, tissue necrosis and metabolic and mechanical recovery of isolated reperfused rat heart as a function of increasing ischemia (1998) Free Radical Research, 28, pp. 25-37 
504 |a Van Boekel, M.A., Meeuwissen, C.A., High-performance liquid chromatography of the bis(dinitrophenyl)hydrazone derivative of ascorbic acid, applied to analysis of ascorbic acid in beer (1983) Journal of Chromatographic Science, 261 (1), pp. 176-180 
520 3 |a Our objective was to compare the antioxidant properties and cardiovascular effects in ischemia-reperfusion of leaves aqueous extracts of Ilex brasiliensis (B) and Ilex paraguariensis (P). In vitro systems were used to assess the antioxidant properties of the extracts. Isolated rat hearts were treated with both extracts before ischemia and myocardial function was assessed. Thiobarbituric acid reactive substances (TBARS) concentration and reduced glutathione (GSH) were also measured. B extract showed higher total phenols and ascorbic acid contents and a higher scavenging activity of peroxynitrite and ferric reducing antioxidant power (FRAP) than P extract. Postischemic systolic and diastolic functions were improved after B and P treatment. Both extracts decreased TBARS and preserved GSH content. The present study demonstrates that an aqueous extract of I. brasiliensis, similar to I. paraguariensis, protects the myocardium against ischemia-reperfusion injury and attenuates oxidative damage. These effects may be attributed to the potent antioxidant properties of the extract. © 2009 Elsevier Ltd. All rights reserved.  |l eng 
593 |a Cátedra de Farmacología Básica, Facultad de Ciencias Médicas, Universidad Nacional de La Plata, Buenos Aires, Argentina 
593 |a Centro de Investigaciones Cardiovasculares, Universidad Nacional de La Plata-CONICET, La Plata, Buenos Aires, Argentina 
593 |a Department of Pharmacognosy and Phytochemistry, School of Pharmacy University of London, United Kingdom 
593 |a LABRAM, Departamento de Ciencias Biológicas, Facultad de Ciencias Exactas, Buenos Aires, Argentina 
690 1 0 |a ANTIOXIDANT CAPACITY 
690 1 0 |a GSH 
690 1 0 |a ILEX BRASILIENSIS 
690 1 0 |a ILEX PARAGUARIENSIS 
690 1 0 |a ISCHEMIA 
690 1 0 |a REPERFUSION 
690 1 0 |a TBARS 
690 1 0 |a ANTIOXIDANT CAPACITY 
690 1 0 |a GSH 
690 1 0 |a ILEX BRASILIENSIS 
690 1 0 |a ILEX PARAGUARIENSIS 
690 1 0 |a ISCHEMIA 
690 1 0 |a REPERFUSION 
690 1 0 |a TBARS 
690 1 0 |a KETONES 
690 1 0 |a ORGANIC ACIDS 
690 1 0 |a PHENOLS 
690 1 0 |a SOLVENT EXTRACTION 
690 1 0 |a CROTON OVALIFOLIUS 
690 1 0 |a ILEX 
690 1 0 |a ILEX BRASILIENSIS 
690 1 0 |a ILEX PARAGUARIENSIS 
690 1 0 |a RATTUS 
700 1 |a Fantinelli, J.C. 
700 1 |a Tournier, H. 
700 1 |a Prieto, J.M. 
700 1 |a Spegazzini, E. 
700 1 |a Debenedetti, S. 
700 1 |a Mosca, S.M. 
773 0 |d 2009  |g v. 42  |h pp. 1403-1409  |k n. 10  |p Food Res. Int.  |x 09639969  |w (AR-BaUEN)CENRE-1760  |t Food Research International 
856 4 1 |u https://www.scopus.com/inward/record.uri?eid=2-s2.0-70349761234&doi=10.1016%2fj.foodres.2009.07.004&partnerID=40&md5=1fb3c28314cb4416113b076a8bf80085  |y Registro en Scopus 
856 4 0 |u https://doi.org/10.1016/j.foodres.2009.07.004  |y DOI 
856 4 0 |u https://hdl.handle.net/20.500.12110/paper_09639969_v42_n10_p1403_Schinella  |y Handle 
856 4 0 |u https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_09639969_v42_n10_p1403_Schinella  |y Registro en la Biblioteca Digital 
961 |a paper_09639969_v42_n10_p1403_Schinella  |b paper  |c PE 
962 |a info:eu-repo/semantics/article  |a info:ar-repo/semantics/artículo  |b info:eu-repo/semantics/publishedVersion 
963 |a VARI 
999 |c 83987