Factors associated with disability in patients with rheumatoid arthritis

OBJECTIVE:: Analyze disability determinants in a cohort of Argentine patients with rheumatoid arthritis (RA). MATERIAL AND METHODS:: Consecutive patients with RA, according to ACR87 criteria, were recruited from 6 rheumatology centers. Demographic and socioeconomic data, family history, comorbid dis...

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Autor principal: Schneeberger, E.E
Otros Autores: Citera, G., Maldonado Cocco, J.A, Salcedo, M., Chiardola, F., Rosemffet, M.G, Marengo, M.F, Papasidero, S., Chaparro Del Moral, R., Rillo, O.L, Bellomio, V., Lucero, E., Spindler, A., Berman, A., Duartes Noe, D., Barreira, J.C, Lázaro, M.A, Paira, S.O
Formato: Capítulo de libro
Lenguaje:Inglés
Publicado: 2010
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Acceso en línea:Registro en Scopus
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024 7 |2 scopus  |a 2-s2.0-77955229009 
024 7 |2 cas  |a Antirheumatic Agents 
040 |a Scopus  |b spa  |c AR-BaUEN  |d AR-BaUEN 
030 |a JCRHF 
100 1 |a Schneeberger, E.E. 
245 1 0 |a Factors associated with disability in patients with rheumatoid arthritis 
260 |c 2010 
270 1 0 |m Citera, G.; Instituto de Rehabilitación Psicofísica, Echeverria 955, Buenos Aires, 1428, Argentina; email: gustavocitera@gmail.com 
506 |2 openaire  |e Política editorial 
504 |a Lee, D.M., Weinblatt, M.E., Rheumatoid arthritis. Review (2001) Lancet., 358, pp. 903-911 
504 |a Young, A., Van Der Heijde, D., Can we predict aggressive disease? Early rheumatoid arthritis (1997) Br J Rheumatol., 11, pp. 27-48 
504 |a Sokka, T., Kankainen, A., Hannonen, P., Scores for functional disability in patients with rheumatoid arthritis are correlated at higher levels with pain scores than with radiographic scores (2000) Arthritis Rheum., 43, pp. 386-389 
504 |a Escalante, A., Del Rincoon, I., How much disability in rheumatoid arthritis is explained by rheumatoid arthritis? (1999) Arthritis Rheum., 42, pp. 1712-1721 
504 |a Sokka, T., Kautiainen, H., Hannanen, P., Changes in Health Assessment Questionnaire disability scores over five years in patients with rheumatoid arthritis compared with the general population (2006) Arthritis Rheum., 54, pp. 3113-3118 
504 |a Giles, J.T., Barlett, S.J., Andersen, R.E., Association of body composition with disability in rheumatoid arthritis: Impact of appendicular fat and lean tissue mass (2008) Arthritis Rheum., 59, pp. 1407-1415 
504 |a Fries, J.F., Spitz, P., Kraines, G., Measurement of patient outcome in arthritis (1980) Arthritis Rheum., 23, pp. 137-145 
504 |a Pincus, T., Summey, J.A., Soraci Jr., C.A., Assessment of patient satisfaction in activities of daily living using a modified Stanford Health Assessment Questionnaire (1983) Arthritis Rheum., 26, pp. 1346-1353 
504 |a Fries, J.F., Spitz, P., Kraines, R.G., Measurement of patient outcomes in arthritis (1992) Arthritis Care Res., 5, pp. 119-129 
504 |a Ward, M.M., Clinical measures in rheumatoid arthritis: Which are most useful in assessing patients? (1993) J Rheumatol., 21, pp. 17-21 
504 |a Van Der Heijde Dmfm, Van't Hof MA, van Riel PLCM, et al. Validity of single variables and composite indices for measuring disease activity in rheumatoid arthritis (1992) Ann Rheum Dis., 51, pp. 177-181 
504 |a Sullivan, F.M., Eagers, R.C., Lynch, K., Assessment of disability caused by rheumatic diseases in general practice (1987) Ann Rheum Dis., 46, pp. 598-600 
504 |a Citera, G., Arriola, M.S., Maldonado Cocco, J.A., Validation and cross cultural adaptation of an Argentine Spanish version of the Health Assessment Questionnaire Disability Index (2004) J Clin Rheumatol., 10, pp. 110-115 
504 |a Esteve Vives, J., Battle-Gualda, E., Reig, A., Spanish version of the Health Assessment Questionnaire: Reliability, validity and transcultural equivalency. Grupo para la Adaptacion del HAQ a la Poblackm Espariola (1993) J Rheumatol., 20, pp. 2116-2122 
504 |a Cardiel, M.H., Abello, B., Alarcoon-Segovia, D., How to measure health status in rheumatoid arthritis in non-English speaking patients: Validation of a Spanish version of the Health Assessment Questionnaire disability index (Spanish HAQ-DI) (1993) Clin Exp Rheumatol., 11, pp. 117-121 
504 |a Arnett, F.C., Edworthy, S.M., Bloch, D.A., The American Rheumatism Association 1987 revised criteria for the classification ofrheumatoid arthritis (1988) Arthritis Rheum., 31, pp. 315-324 
504 |a (1994) Assessment of Fracture Risk and Its Application to Screening for Postmenopausal Osteoporosis, , World Health Organization Study Group World Health Organization, Geneva, Switzerland 
504 |a Van Der Heijde, D.M., Van'T Hof, M., Van Riel, P.L., Development of a disease activity score based on judgment in clinical practice by rheumatolo- gists (1993) J Rheumatol., 20, pp. 579-581 
504 |a Hochberg, M.C., Chang, R.W., Dwosh, I., The American College of Rheumatology 1991 revised criteria for the classification of global functional status in rheumatoid arthritis (1992) Arthritis Rheum., 35, pp. 498-502 
504 |a Van Der Heijde, D., How to read radiographs according to the Sharp/van der Heijde method (2000) J Rheumatol., 27, pp. 261-263 
504 |a Wolfe, F., Pincus, T., Listening to the patient. A practical guide to self-report questionnaires in clinical care (1999) Arthritis Rheum., 42, pp. 1797-1808 
504 |a Wolfe, F., Pincus, T., An infrastructure of patient questionnaire at each rheumatology visit: Improving efficiency and documenting care (2000) J Rheumatol., 27, pp. 2727-2730 
504 |a Eberhardt, K.B., Rydgren, L.C., Petterson, H., Early rheumatoid arthritis- onset, course, and outcome over 2 years (1990) Rheumatol Int., 10, pp. 135-142 
504 |a Courvoisier, N., Dougados, M., Cantagrel, A., Prognostic factors of 10-year radiographic outcome in early rheumatoid arthritis: A prospective study (2008) Arthrtis Res Ther., 10, pp. R106 
504 |a Oken, O., Batur, G., Gundiiz, R., Factors associated with functional disability in patients with rheumatoid arthritis (2008) Rheumatol Int., 29, pp. 163-166 
504 |a Rupp, I., Boshuizen, H.C., Dinant, H.J., Disability and health-related quality of life among patients with rheumatoid arthritis: Association with radiographic joint damage, disease activity, pain, and depressive symptoms (2006) Scand JRheu- Matol., 35, pp. 175-181 
504 |a Eth, M., Voskuyl, A.E., Bac, D., Functional disability in relation to radiological damage and disease activity in patients with rheumatoid arthritis (2002) J Rheumatol., 29, pp. 267-270 
504 |a Kirwan, J.R., Conceptual issues in scoring radiographic progression in rheumatoid arthritis (1999) J Rheumatol., 26, pp. 720-725 
504 |a Plant, M.J., O'Sullivan, M.M., Lewis, P.A., What factors influence functional ability in patients with rheumatoid arthritis. Do they alter over time? (2005) Rheumatology (Oxford), 44, pp. 1181-1185 
504 |a Odegard, S., Landewe, R., Van Der Heijde, D., Association of early radiographic damage with impaired physical function in rheumatoid arthritis: A ten year, longitudinal observational study in 238 patients (2006) Arthritis Rheum., 54, pp. 68-75 
504 |a Leigh, J.P., Fries, J.F., Predictors of disability in a longitudinal sample of patients with rheumatoid arthritis (1992) Ann Rheum Dis., 51, pp. 581-587 
504 |a Young, A., Dixey, J., Cox, N., How does functional disability in early rheumatoid arthritis (RA) affect patients and their lives? Results of 5 years of follow-up in 732 patients from the Early RA Study (ERAS) (2000) Rheumatology., 39, pp. 603-611 
504 |a Wolfe, F., Determinants of WOMAC function, pain and stiffness scores: Evidence for the role of low back pain, symptom counts, fatigue and depression in osteoarthritis, rheumatoid arthritis and fibromyalgia (1999) Rheumatology (Oxford), 38, pp. 355-361 
504 |a Palkonyai, E., Kolarz, G., Kopp, M., Depressive symptoms in early rheumatoid arthritis: A comparative longitudinal study (2007) Clin Rheumatol., 26, pp. 753-758 
504 |a Han, C., Rahman, M.U., Doyle, M.K., Association of anemia and physical disability among patients with rheumatoid arthritis (2007) J Rheumatol., 34, pp. 2177-2182 
504 |a Grigor, C., Capell, H., Stirling, A., Effect of a treatment strategy of tight control for rheumatoid arthritis (the TICORA study): A single-blind randomised controlled trial (2004) Lancet., 364, pp. 263-269 
504 |a Sokka, T., Kautiainen, H., Pincus, T., Disparities in rheumatoid arthritis disease activity according to gross domestic product in 25 countries in the QUEST-RA database (2009) Ann Rheum Dis., 68, pp. 1666-1672 
520 3 |a OBJECTIVE:: Analyze disability determinants in a cohort of Argentine patients with rheumatoid arthritis (RA). MATERIAL AND METHODS:: Consecutive patients with RA, according to ACR87 criteria, were recruited from 6 rheumatology centers. Demographic and socioeconomic data, family history, comorbid diseases, extra-articular manifestations and information about received treatments were provided. Disease activity was assessed using Disease Activity Score 28 (DAS 28) and the Health Assessment Questionnaire (HAQ)-A was used for the functional capacity. Hand and feet radiographs were assessed using Sharp-van der Heijde score. RESULTS:: A total of 640 patients with RA were included, of which 85.2% were females. Mean age was 53 years (interquartile range [IQR], 44-62) and mean disease duration was 8 years (IQR, 4-14). DAS 28 mean was 2.72 (IQR, 1.7-3.7) and HAQ-A mean was 0.62 (IQR, 0.13-1.25). Multiple linear regression showed that the main variables associated with disability were DAS 28, radiologic damage and age. Main predictors of functional disability in the multiple logistic regression using severe HAQ (>2) as dependent variable were DAS 28 (OR, 2; P < 0.0001); age (OR, 1; P = 0.008); and structural damage (OR, 1; P = 0.001). CONCLUSIONS:: In this population, the disease activity was the variable that showed the highest impact on the physical function. Radiologic damage affected HAQ as the disease progressed. © 2010 by Lippincott Williams & Wilkins.  |l eng 
593 |a Instituto de Rehabilitación Psicofísica, Echeverria 955, Buenos Aires, 1428, Argentina 
593 |a Hospital Tornú, Buenos Aires, Argentina 
593 |a Hospital Padilla, Tucumán, Argentina 
593 |a Hospital Británico, Buenos Aires, Argentina 
593 |a Hospital Cullen Santa Fé, Fundación Reumatológica Argentina dr O García Morteo, Santa Fé, Argentina 
690 1 0 |a DISCAPACITY 
690 1 0 |a DISEASE ACTIVITY 
690 1 0 |a RHEUMATOID ARTHRITIS 
690 1 0 |a ADULT 
690 1 0 |a ARTICLE 
690 1 0 |a COMORBIDITY 
690 1 0 |a CONTROLLED STUDY 
690 1 0 |a DEMOGRAPHY 
690 1 0 |a DEPENDENT VARIABLE 
690 1 0 |a DISABILITY 
690 1 0 |a DISEASE ACTIVITY 
690 1 0 |a DISEASE DURATION 
690 1 0 |a FAMILY HISTORY 
690 1 0 |a FEMALE 
690 1 0 |a FUNCTIONAL STATUS 
690 1 0 |a HEALTH ASSESSMENT QUESTIONNAIRE 
690 1 0 |a HUMAN 
690 1 0 |a MAJOR CLINICAL STUDY 
690 1 0 |a MALE 
690 1 0 |a MULTIPLE LINEAR REGRESSION ANALYSIS 
690 1 0 |a PRIORITY JOURNAL 
690 1 0 |a RADIOGRAPHY 
690 1 0 |a RHEUMATOID ARTHRITIS 
690 1 0 |a SOCIOECONOMICS 
690 1 0 |a ADULT 
690 1 0 |a ANTIRHEUMATIC AGENTS 
690 1 0 |a ARTHRITIS, RHEUMATOID 
690 1 0 |a COHORT STUDIES 
690 1 0 |a COMORBIDITY 
690 1 0 |a DISABILITY EVALUATION 
690 1 0 |a DISEASE PROGRESSION 
690 1 0 |a FEMALE 
690 1 0 |a FOOT JOINTS 
690 1 0 |a HAND JOINTS 
690 1 0 |a HEALTH SURVEYS 
690 1 0 |a HUMANS 
690 1 0 |a LOGISTIC MODELS 
690 1 0 |a MALE 
690 1 0 |a MIDDLE AGED 
690 1 0 |a SEVERITY OF ILLNESS INDEX 
651 4 |a ARGENTINA 
651 4 |a ARGENTINA 
700 1 |a Citera, G. 
700 1 |a Maldonado Cocco, J.A. 
700 1 |a Salcedo, M. 
700 1 |a Chiardola, F. 
700 1 |a Rosemffet, M.G. 
700 1 |a Marengo, M.F. 
700 1 |a Papasidero, S. 
700 1 |a Chaparro Del Moral, R. 
700 1 |a Rillo, O.L. 
700 1 |a Bellomio, V. 
700 1 |a Lucero, E. 
700 1 |a Spindler, A. 
700 1 |a Berman, A. 
700 1 |a Duartes Noe, D. 
700 1 |a Barreira, J.C. 
700 1 |a Lázaro, M.A. 
700 1 |a Paira, S.O. 
773 0 |d 2010  |g v. 16  |h pp. 215-218  |k n. 5  |p J. Clin. Rheumatol.  |x 10761608  |t Journal of Clinical Rheumatology 
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