Transmission and dynamics of tuberculosis on generalized households

Tuberculosis (TB) transmission is enhanced by systematic exposure to an infectious individual. This enhancement usually takes place at either the home, workplace, and/or school (generalized household). Typical epidemiological models do not incorporate the impact of generalized households on the stud...

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Autor principal: Aparicio, Juan Pablo
Otros Autores: Capurro, A.F, Castillo-Chavez, C.
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Lenguaje:Inglés
Publicado: Academic Press 2000
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100 1 |a Aparicio, Juan Pablo 
245 1 0 |a Transmission and dynamics of tuberculosis on generalized households 
260 |b Academic Press  |c 2000 
270 1 0 |m Aparicio, J.P.; Department of Biometrics, 432 Warren Hall, Cornell University, Ithaca, NY 14853-7801, United States; email: jpa9@cornell.edu 
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504 |a Castillo-Chavez, C., Feng, Z., Mathematical models for the disease dynamics of tuberculosis (1996), Advances in Mathematical Population Dynamics - Molecules, ells and Man (Arino, O., Axelrod D. and Kimmel, eds). Singapore: World Scientific; Castillo-Chavez, C., Feng, Z., To treat or not to treat, the case of tuberculosis (1997) J. Math. Biol., 35, pp. 629-659 
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504 |a Riley, R.L., Mills, C.C., O'Grady, F., Sultan, L.U., Wittsdat, F., Shivpuri, D.N., Infectiousness of air from a tuberculosis ward (1962) Am. Rev. Respir. Dis., 85, pp. 511-525 
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506 |2 openaire  |e Política editorial 
520 3 |a Tuberculosis (TB) transmission is enhanced by systematic exposure to an infectious individual. This enhancement usually takes place at either the home, workplace, and/or school (generalized household). Typical epidemiological models do not incorporate the impact of generalized households on the study of disease dynamics. Models that incorporate cluster (generalized household) effects and focus on their impact on TB's transmission dynamics are developed. Detailed models that consider the effect of casual infections, that is, those generated outside a cluster, are also presented. We find expressions for the Basic Reproductive Number as a function of cluster size. The formula for R0 separates the contributions of cluster and casual infections in the generation of secondary TB infections. Relationships between cluster and classical epidemic models are discussed as well as the concept of critical cluster size. (C) 2000 Academic Press.  |l eng 
536 |a Detalles de la financiación: National Security Agency 
536 |a Detalles de la financiación: FP7 International Cooperation, 950809 
536 |a Detalles de la financiación: Universidad de Buenos Aires 
536 |a Detalles de la financiación: National Science Foundation 
536 |a Detalles de la financiación: We thank Moira Zellner and Baojoun Song for valuable discussions. This work has been partially supported by Universidad de Buenos Aires fellowship to Juan Aparicio, by INCO grant no. 950809 of Commision of European Community-Directorate General XII to Angel F. Capurro. This research was conducted while CCC was a member of the Institute for Mathematics and its applications at the University of Minnesota and a visiting Professor at Howard University, Washington, D.C. This research was also supported by NSF and NSA grants to the Mathematical and Theoretical Biology Institute at Cornell University. 
593 |a Departamento De Física, Facultad De Ciencias Exactas Y Naturales, Ciudad Universitaria, 1428, Buenos Aires, Argentina 
593 |a Departamento De Investigación, Universidad De Belgrano, Zabala 1851, Piso 12, 1426, Buenos Aires, Argentina 
593 |a Laboratorio De Ecología, Universidad Nacional De Luján-CONICET, Ruta 5 y 7, 6700, Luján, Argentina 
593 |a Theoretical Biology Institute, Cornell University, 431 Warren Hall, Ithaca, NY 14853-7801, United States 
593 |a Department of Theoretical and Applied Mechanics, Cornell University, 317 Kimball Hall, Ithaca, NY 14853-1503, United States 
650 1 7 |2 spines  |a TUBERCULOSIS 
690 1 0 |a AIRBORNE PARTICLE 
690 1 0 |a ARTICLE 
690 1 0 |a DISEASE TRANSMISSION 
690 1 0 |a EPIDEMIC 
690 1 0 |a HOUSEHOLD 
690 1 0 |a MODEL 
690 1 0 |a PRIORITY JOURNAL 
700 1 |a Capurro, A.F. 
700 1 |a Castillo-Chavez, C. 
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