Cell entry of dengue virus

Dengue virus is an expanding public health problem in tropical and subtropical regions of the world, mainly owing to failure in the maintenance of control programs for the mosquito vector Aedes aegypti and increasing and unplanned urbanization. It has been estimated that over 50 million dengue virus...

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Autor principal: Acosta, E.G
Otros Autores: Talarico, L.B, Damonte, E.B
Formato: Capítulo de libro
Lenguaje:Inglés
Publicado: 2008
Acceso en línea:Registro en Scopus
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Registro en la Biblioteca Digital
Aporte de:Registro referencial: Solicitar el recurso aquí
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100 1 |a Acosta, E.G. 
245 1 0 |a Cell entry of dengue virus 
260 |c 2008 
270 1 0 |m Damonte, E.B.; Laboratorio de Virología, Departamento de Química Biológica, Universidad de Buenos Aires, Pabellón 2, Piso 4, 1428 Buenos Aires, Argentina; email: edamonte@qb.fcen.uba.ar 
506 |2 openaire  |e Política editorial 
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520 3 |a Dengue virus is an expanding public health problem in tropical and subtropical regions of the world, mainly owing to failure in the maintenance of control programs for the mosquito vector Aedes aegypti and increasing and unplanned urbanization. It has been estimated that over 50 million dengue virus infections of varying severity occur globally each year. making this virus the most significant mosquito-borne human pathogen. However, there is no specific antiviral therapy or vaccine for treatment or prevention. This review focuses on recent data describing the putative molecules and mechanisms involved in the complex process of dengue virus binding and entry into mosquito and mammalian cells in primary infections. Furthermore, the perspectives of these early events in the virus life cycle as a target for antidengue therapeutic strategies are also considered. © 2008 Future Medicine Ltd.  |l eng 
593 |a Laboratorio de Virología, Departamento de Química Biológica, Universidad de Buenos Aires, Pabellón 2, Piso 4, 1428 Buenos Aires, Argentina 
690 1 0 |a ANTIVIRAL THERAPY 
690 1 0 |a DENGUE VIRUS 
690 1 0 |a ENVELOPE E GLYCOPROTEIN 
690 1 0 |a FLAVIVIRUS 
690 1 0 |a RECEPTOR 
690 1 0 |a VIRUS ATTACHMENT 
690 1 0 |a VIRUS ENTRY 
690 1 0 |a AMANTADINE 
690 1 0 |a CD14 ANTIGEN 
690 1 0 |a CHLORPROMAZINE 
690 1 0 |a CONCANAVALIN A 
690 1 0 |a GALACTAN 
690 1 0 |a GLUCAN 
690 1 0 |a GLUCOSE REGULATED PROTEIN 78 
690 1 0 |a GLYCOPROTEIN E1 
690 1 0 |a HEAT SHOCK PROTEIN 70 
690 1 0 |a HEAT SHOCK PROTEIN 90 
690 1 0 |a HEPARIN 
690 1 0 |a LAMININ RECEPTOR 
690 1 0 |a LECTIN 
690 1 0 |a MANNOSE RECEPTOR 
690 1 0 |a PENTOSAN POLYSULFATE 
690 1 0 |a PI 88 
690 1 0 |a POLYANION 
690 1 0 |a RIMANTADINE 
690 1 0 |a SURAMIN 
690 1 0 |a SYNTHETIC PEPTIDE 
690 1 0 |a TETRACYCLINE DERIVATIVE 
690 1 0 |a TUBULIN 
690 1 0 |a VIRUS RECEPTOR 
690 1 0 |a ANTIVIRAL ACTIVITY 
690 1 0 |a DENGUE 
690 1 0 |a DENGUE VIRUS 
690 1 0 |a HOST RANGE 
690 1 0 |a HUMAN 
690 1 0 |a LIFE CYCLE 
690 1 0 |a NONHUMAN 
690 1 0 |a PRIORITY JOURNAL 
690 1 0 |a PROTEIN FUNCTION 
690 1 0 |a PROTEIN TARGETING 
690 1 0 |a REVIEW 
690 1 0 |a VIRION 
690 1 0 |a VIRUS ATTACHMENT 
690 1 0 |a VIRUS ENTRY 
690 1 0 |a VIRUS REPLICATION 
690 1 0 |a AEDES AEGYPTI 
690 1 0 |a DENGUE VIRUS 
690 1 0 |a FLAVIVIRUS 
690 1 0 |a MAMMALIA 
700 1 |a Talarico, L.B. 
700 1 |a Damonte, E.B. 
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