In vitro and in vivo activity of eugenol on human herpesvirus
Eugenol (4-allyl-1-hydroxy-2-methoxybenzene) was tested for antiviral activity against HSV-1 and HSV-2 viruses. In vitro, it was found that the replication of these viruses was inhibited in the presence of this compound. Inhibitory concentration 50% values for the anti-HSV effects of eugenol were 25...
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2000
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| LEADER | 12744caa a22014177a 4500 | ||
|---|---|---|---|
| 001 | PAPER-2220 | ||
| 003 | AR-BaUEN | ||
| 005 | 20230518203137.0 | ||
| 008 | 190411s2000 xx ||||fo|||| 00| 0 eng|d | ||
| 024 | 7 | |2 scopus |a 2-s2.0-0033763575 | |
| 024 | 7 | |2 cas |a Acyclovir, 59277-89-3; Antiviral Agents; Drug Combinations; Eugenol, 97-53-0 | |
| 040 | |a Scopus |b spa |c AR-BaUEN |d AR-BaUEN | ||
| 030 | |a PHYRE | ||
| 100 | 1 | |a Benencia, F. | |
| 245 | 1 | 3 | |a In vitro and in vivo activity of eugenol on human herpesvirus |
| 260 | |c 2000 | ||
| 270 | 1 | 0 | |m Benencia, F.; Laboratorio de Inmunoquimica, Dpto. Quimica Biologica, Universidad de Buenos Aires, Ciudad Universitaria, 1428 Buenos Aires, Argentina; email: fbenen@qb.fcen.uba.ar |
| 506 | |2 openaire |e Política editorial | ||
| 504 | |a Agarwal, K.C., Therapeutic actions of garlic oil constituents (1996) Med. Res. Rev., 16, pp. 111-124 | ||
| 504 | |a Ahmad, A., Davies, J., Randall, S., Skinner, G.R.B., Antiviral properties of extract of Opuntia streptacantha (1996) Antivir. Res., 30, pp. 75-80 | ||
| 504 | |a Al-Zuhair, H., El-Sayeh, B., Ameen, H.A., Al-Shoora, H., Pharmacological studies of cardamom oil in animals (1996) Pharmacol. Res., 34, pp. 79-82 | ||
| 504 | |a Aruoma, O.I., Spencer, J.P.E., Rossi, R., An evaluation of the antioxidant and antiviral actions of extracts of rosemary and provencal herbs (1996) Food Chem. Toxicol., 34, pp. 449-456 | ||
| 504 | |a Babu, J.S., Thomas, J., Kanangat, S., Morrison, L.A., Knipe, D.M., Rouse, B.T., Viral replication is required for induction of ocular immunopathology by herpes simplex virus (1996) J. Virol., 70, pp. 101-107 | ||
| 504 | |a Barquero, A.A., Alche, L.E., Coto, C.E., Antiviral activity of meliacine on the replication of a thymidine kinase deficient mutant of herpes simplex virus type 1 alone and in combination with acyclovir (1997) Int. J. Antimicrob. Agents, 9, pp. 49-55 | ||
| 504 | |a Benencia, F., Courreges, M.C., Coulombie, F.C., Antiviral activity of a crude fraction of polysaccharides obtained from leaves of Trichilia glabra (1997) Fitoterapia, 68, pp. 173-176 | ||
| 504 | |a Briozzo, J., Nunez, L., Chirife, J., Herszage, L., D'Aquino, M., Antimicrobial activity of clove oil dispersed in a concentrated sugar solution (1989) J. Appl. Bacteriol., 66, pp. 69-75 | ||
| 504 | |a De Rodriguez, D.J., Chulia, J., Simoes, C.M., Amoros, M., Mariotte, A.M., Girre, L., Search for in vitro antiviral activity of new isoflavonic glycoside from Ulex europaeus (1990) Planta Med., 56, pp. 59-62 | ||
| 504 | |a Didry, N., Dubreuil, L., Pinkas, M., Activity of thymol, carvacrol, cinnamaldehyde and eugenol on oral bacteria (1994) Pharm. Acta. Helv., 69, pp. 25-28 | ||
| 504 | |a Fu, N., Antioxidant action of garlic oil and allitridi (1993) Chung Kuo I Hsueh Yuan Hsueh Pao, 15, pp. 295-301 | ||
| 504 | |a Fukuchi, K., Sagakami, H., Okuda, T., Inhibition of herpes simplex virus infections by tannins and related compounds (1989) Antivir. Res., 11, pp. 285-298 | ||
| 504 | |a Garg, S.C., Siddiqui, N., Antifungal activity of some essential oil isolates (1992) Pharmazie, 47, pp. 467-468 | ||
| 504 | |a Irie, H., Shimeld, C., Williams, N., Hill, T., Protection against ocular and cutaneous infection with herpes simplex virus type 1 by intragastric immunization with live virus (1993) J. Gen. Virol., 74, pp. 1357-1362 | ||
| 504 | |a Ito, M., Barron, A.L., Inactivation of HSV by concanavalin A (1974) J. Virol., 13, pp. 1312-1318 | ||
| 504 | |a Ito, M., Girin, L., Barron, A.L., Inactivation of HCMV by PHA (1978) Arch. Virol., 57, pp. 97-105 | ||
| 504 | |a Kurokawa, M., Nagasaka, K., Hirabayashi, T., Efficacy of traditional herbal medicines in combination with acyclovir against herpes simplex virus type 1 infection in vitro and in vivo (1995) Antivir. Res., 27, pp. 19-37 | ||
| 504 | |a Kurokawa, M., Ochiai, H., Nagasaka, K., Antiviral traditional medicines against herpes simplex virus (HSV-1), poliovirus, and measles virus in vitro and their therapeutic efficacies for HSV-1 infection in mice (1993) Antivir. Res., 22, pp. 175-188 | ||
| 504 | |a Lifson, J., Coutre, S., Huang, E., Engleman, E., Role of envelope glycoprotein carbohydrate in human immunodeficiency virus (HIV) infectivity and virus induced cell fusion (1986) J. Exp. Med., 164, pp. 2101-2106 | ||
| 504 | |a Locher, C.P., Witvrow, M., De Bethune, M.P., Antiviral activity of Hawaiian medicinal plants against human immunodeficiency virus type-1 (HIV-1) (1996) Phytomedicine, 2, pp. 259-264 | ||
| 504 | |a Markowitz, K., Moynihan, M., Liu, M., Kim, S., Biological properties of eugenol and zinc oxide-eugenol. A clinically oriented review (1992) Oral. Sur. Oral. Med. Oral. Pathol., 73, pp. 729-737 | ||
| 504 | |a Moran, A., Martin, M.L., Montero, M.J., Ortiz de Urbina, A.V., Sevilla, M.A., San Roman, L., Analgesic, antipyretic and anti-inflammatory activity of the essential oil of Artemissia caerulescens subsp gallica (1989) J. Ethnopharmacol., 27, pp. 307-317 | ||
| 504 | |a Nagababu, E., Laksmaiah, N., Inhibitor effect of eugenol on non-enzymatic lipid peroxidation in rat liver mitochondria (1992) Biochem. Pharmac., 43, pp. 2393-2400 | ||
| 504 | |a Nagata, K., Sagakami, H., Harada, H., Nonoyama, M., Ishihama, A., Konno, K., Inhibition of influenza virus infection by cone antitumor substances (1990) Antivir. Res., 13, pp. 11-21 | ||
| 504 | |a Nenoff, P., Haustein, U.F., Brandt, W., Antifungal activity of the essential oil of Melaleuca alternifolia (Tea tree oil) against pathogenic fungi in vitro (1996) Skin Pharmacol., 9, pp. 388-394 | ||
| 504 | |a Pacheco, P., Sierra, J., Schmeda-Hirschmann, G., Potter, C.W., Jones, B.M., Moshref, M., Antiviral activity of Chilean medicinal plant extracts (1993) Phytother. Res., 7, pp. 415-418 | ||
| 504 | |a Palamara, A.T., Perno, C.F., Ciriolo, M.R., Evidence for antiviral activity of glutathione: In vitro inhibition of herpes simplex virus type 1 replication (1995) Antivir. Res., 27, pp. 237-253 | ||
| 504 | |a Phadke, S.A., Kulkarni, S.D., Screening of in vitro antibacterial activity of Terminalia chebula, Eclapta alba and Ocimum sanctum (1989) Indian J. Med. Sci., 43, pp. 113-117 | ||
| 504 | |a Prichard, M.N., Shipman C.H., Jr., A three-dimensional model to analyze drug-drug interactions (1990) Antivir. Res., 14, pp. 181-206 | ||
| 504 | |a Reed, L.J., Muench, H., A simple method of estimating fifty per cent end points (1938) Am. J. Hyg., 27, pp. 493-501 | ||
| 504 | |a Rompelberg, C.J.M., Verhagen, H., Van Bladeren, P.J., Effects of the naturally occuring alkenylbenzenes eugenol and trans-anethole on drug metabolizing enzymes in rat liver (1993) Food Chem. Toxicol., 31, pp. 637-645 | ||
| 504 | |a Saeki, Y., Shibata, M., Sato, Y., Okuda, K., Takazoe, I., Antimicrobial action of natural substances on oral bacteria (1989) Bull. Tokyo Dent. Coll., 30, pp. 129-135 | ||
| 504 | |a Sagakami, H., Kawazoe, Y., Komatsu, N., Antitumour, antiviral and immunopotentiating activities of pine cone extracts: Potential medicinal effect of natural and synthetic lignin related materials (1991) Anticancer Res., 11, pp. 881-888 | ||
| 504 | |a Shapiro, S., Meier, A., Guggenheim, B., The antimicrobial activity of essential oils and essential oil components towards oral bacteria (1994) Oral Microbiol. Immunol., 9, pp. 202-208 | ||
| 504 | |a Singh, S., Majumdar, D.K., Rehan, H.M., Evaluation of anti-inflammatory potential of fixed oil of Ocimum sanctum (Holybasil) and its possible mechanism of action (1996) J. Ethnopharm., 54, pp. 19-26 | ||
| 504 | |a Sticht, F.D., Smith, R.M., Eugenol: Some pharmacologic observations (1971) J. Dent. Res., 50, pp. 1531-1535 | ||
| 504 | |a Sudo, K., Konno, K., Yokota, T., Shigeta, S., A sensitive assay system for screening antiviral compounds against herpes simplex virus type 1 and type 2 (1994) J. Virol. Methods, 49, pp. 169-178 | ||
| 504 | |a Suzuki, H., Tochikura, T.S., Liyama, K., Yamasaki, S., Yamamoto, N., Toda, S., Lignosulfonate, a water solubilized lignin from the waste liquor of the pulping process, inhibits the infectivity and cytopathic effects of human immunodeficiency virus in vitro (1989) Agricol. Biol. Chem., 53, pp. 3369-3372 | ||
| 504 | |a Tabba, H.D., Chang, R.S., Smith, K.M., Isolation, purification and partial characterization of prunellin, and anti-HIV compound from aqueous extracts of Prunella vulgaris (1989) Antivir. Res., 11, pp. 263-274 | ||
| 504 | |a Thorne, H.V., Clarke, G.F., Skuce, R., The inactivation of herpes simplex virus by some solanaceae glycoalkaloids (1985) Antivir. Res., 5, pp. 335-343 | ||
| 504 | |a Upadhayay, S.N., Dhawan, S., Garg, S., Talwar, G.P., Immunomodulatory effects of neem (Azadirachta indica) oil (1992) Int. J. Immunopharm., 14, pp. 1187-1193 | ||
| 504 | |a Woody, T.L., Davis, R.D., The effect of eugenol-containing and eugenol-free temporary cements on microleakage in resin bonded restorations (1992) Oper. Dent., 17, pp. 175-180 | ||
| 504 | |a Zgorniak-Nowosielka, I., Manolova, N., Serkedjieva, J., A study on the antiviral action of polyphenolic complex isolated from the medicinal plant Geranium sanguineum L. VIII. Inhibitory effect on reproduction of herpes simplex virus type 1 (1989) Acta Microbiol. Bulg., 24, pp. 3-8 | ||
| 520 | 3 | |a Eugenol (4-allyl-1-hydroxy-2-methoxybenzene) was tested for antiviral activity against HSV-1 and HSV-2 viruses. In vitro, it was found that the replication of these viruses was inhibited in the presence of this compound. Inhibitory concentration 50% values for the anti-HSV effects of eugenol were 25.6 μg/mL and 16.2 μg/mL for HSV-1 and HSV-2 respectively, 250 μg/mL being the maximum dose at which cytotoxicity was tested. Eugenol was virucidal and showed no cytotoxicity at the concentrations tested. Eugenol-acyclovir combinations synergistically inhibited herpesvirus replication in vitro. Topical application of eugenol delayed the development of herpesvirus induced keratitis in the mouse model. (C) 2000 John Wiley and Sons, Ltd. |l eng | |
| 593 | |a Departamento Qumica Biolgica, Facultad de Ciencias Exactas y Naturales, Ciudad Universitaria, 1428 Buenos Aires, Argentina | ||
| 593 | |a Centro de Patologa Experimental, Facultad de Medicina, Universidad de Buenos Aires, Uriburu 950. 5to. Piso, 1115 Buenos Aires, Argentina | ||
| 593 | |a Laboratorio de Inmunoqumica, Dpto. Qumica Biolgica, Ciudad Universitaria, 1428 Buenos Aires, Argentina | ||
| 690 | 1 | 0 | |a ACYCLOVIR |
| 690 | 1 | 0 | |a ANTIVIRAL ACTIVITY |
| 690 | 1 | 0 | |a EUGENOL |
| 690 | 1 | 0 | |a HERPESVIRUS |
| 690 | 1 | 0 | |a HERPETIC KERATITIS |
| 690 | 1 | 0 | |a ACICLOVIR |
| 690 | 1 | 0 | |a EUGENOL |
| 690 | 1 | 0 | |a ANIMAL CELL |
| 690 | 1 | 0 | |a ANIMAL EXPERIMENT |
| 690 | 1 | 0 | |a ANIMAL MODEL |
| 690 | 1 | 0 | |a ANTIVIRAL ACTIVITY |
| 690 | 1 | 0 | |a ARTICLE |
| 690 | 1 | 0 | |a CONTROLLED STUDY |
| 690 | 1 | 0 | |a CYTOTOXICITY |
| 690 | 1 | 0 | |a DRUG MIXTURE |
| 690 | 1 | 0 | |a DRUG POTENTIATION |
| 690 | 1 | 0 | |a HERPES SIMPLEX KERATITIS |
| 690 | 1 | 0 | |a HERPES SIMPLEX VIRUS 1 |
| 690 | 1 | 0 | |a HERPES SIMPLEX VIRUS 2 |
| 690 | 1 | 0 | |a HERPES VIRUS INFECTION |
| 690 | 1 | 0 | |a IC 50 |
| 690 | 1 | 0 | |a MOUSE |
| 690 | 1 | 0 | |a NONHUMAN |
| 690 | 1 | 0 | |a PHYTOTHERAPY |
| 690 | 1 | 0 | |a VERO CELL |
| 690 | 1 | 0 | |a VIRUS REPLICATION |
| 690 | 1 | 0 | |a ACYCLOVIR |
| 690 | 1 | 0 | |a ANIMALS |
| 690 | 1 | 0 | |a ANTIVIRAL AGENTS |
| 690 | 1 | 0 | |a CERCOPITHECUS AETHIOPS |
| 690 | 1 | 0 | |a DISEASE MODELS, ANIMAL |
| 690 | 1 | 0 | |a DOSE-RESPONSE RELATIONSHIP, DRUG |
| 690 | 1 | 0 | |a DRUG COMBINATIONS |
| 690 | 1 | 0 | |a EUGENOL |
| 690 | 1 | 0 | |a HERPES SIMPLEX |
| 690 | 1 | 0 | |a HERPESVIRUS 1, HUMAN |
| 690 | 1 | 0 | |a HERPESVIRUS 2, HUMAN |
| 690 | 1 | 0 | |a HUMANS |
| 690 | 1 | 0 | |a MICE |
| 690 | 1 | 0 | |a MICE, INBRED BALB C |
| 690 | 1 | 0 | |a MICROBIAL SENSITIVITY TESTS |
| 690 | 1 | 0 | |a VERO CELLS |
| 690 | 1 | 0 | |a ANIMALIA |
| 690 | 1 | 0 | |a HERPES |
| 690 | 1 | 0 | |a HERPESVIRIDAE |
| 690 | 1 | 0 | |a HUMAN HERPESVIRUS 1 |
| 690 | 1 | 0 | |a HUMAN HERPESVIRUS 2 |
| 700 | 1 | |a Courrges, M.C. | |
| 773 | 0 | |d 2000 |g v. 14 |h pp. 495-500 |k n. 7 |p Phytother. Res. |x 0951418X |t Phytotherapy Research | |
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