Differential inhibitory action of two azoic compounds against arenaviruses
The action of five azo-based compounds against the arenaviruses Junin (JUNV) and Tacaribe (TCRV) was evaluated in vitro by a virus yield inhibition assay in Vero cells and a cell-free virion inactivation assay. The compound 2-azo-(1′-(2′-nitroso)naphthyl)-benzoate (ANNB) was the most effective inhib...
Guardado en:
| Autor principal: | |
|---|---|
| Otros Autores: | , |
| Formato: | Capítulo de libro |
| Lenguaje: | Inglés |
| Publicado: |
Elsevier
2003
|
| Acceso en línea: | Registro en Scopus DOI Handle Registro en la Biblioteca Digital |
| Aporte de: | Registro referencial: Solicitar el recurso aquí |
| LEADER | 09439caa a22010697a 4500 | ||
|---|---|---|---|
| 001 | PAPER-21544 | ||
| 003 | AR-BaUEN | ||
| 005 | 20230518205301.0 | ||
| 008 | 190411s2003 xx ||||fo|||| 00| 0 eng|d | ||
| 024 | 7 | |2 scopus |a 2-s2.0-0037384516 | |
| 040 | |a Scopus |b spa |c AR-BaUEN |d AR-BaUEN | ||
| 030 | |a IAAGE | ||
| 100 | 1 | |a García, C.C. | |
| 245 | 1 | 0 | |a Differential inhibitory action of two azoic compounds against arenaviruses |
| 260 | |b Elsevier |c 2003 | ||
| 270 | 1 | 0 | |m Damonte, E.B.; Depto. de Quim. Biológica, Universidad de Buenos Aires, Ciudad Universitaria, Piso 4, Buenos Aires 1428, Argentina; email: edamonte@qb.fcen.uba.ar |
| 506 | |2 openaire |e Política editorial | ||
| 504 | |a Damonte, E.B., Junin virus (2002) Wiley Encyclopedia of Molecular Medicine, pp. 1844-1846. , T.E. Creighton. New York: Wiley | ||
| 504 | |a Enria, D.A., Maiztegui, J.I., Antiviral treatment of Argentine hemorrhagic fever (1994) Antiviral Res., 23, pp. 23-31 | ||
| 504 | |a Andrei, G., De Clercq, E., Inhibitory effect of selected antiviral compounds on arenavirus replication in vitro (1990) Antiviral Res., 14, pp. 287-300 | ||
| 504 | |a Candurra, N.A., Maskin, L., Damonte, E.B., Inhibition of arenavirus multiplication in vitro by phenotiazines (1996) Antiviral Res., 31, pp. 149-158 | ||
| 504 | |a Cordo, S.M., Candurra, N.A., Damonte, E.B., Myristic acid analogs are inhibitors of Junin virus replication (1999) Microbes Infect., 1, pp. 609-614 | ||
| 504 | |a Bartolotta, S., García, C.C., Candurra, N.A., Damonte, E.B., Effect of fatty acids on arenavirus replication: Inhibition of virus production by lauric acid (2001) Arch. Virol., 146, pp. 777-790 | ||
| 504 | |a García, C.C., Candurra, N.A., Damonte, E.B., Antiviral and virucidal activities against arenaviruses of zinc-finger active compounds (2000) Antiviral Chem. Chemother., 11, pp. 231-238 | ||
| 504 | |a Martínez Peralta, L.A., Coto, C.E., Weissenbacher, M.C., The Tacaribe complex: Relationship between a pathogenic (Junin) and a nonpathogenic (Tacaribe) arenavirus (1993) The Arenaviridae, , M.S. Salvato. New York: Plenum Press | ||
| 504 | |a Damonte, E.B., Mersich, S.E., Candurra, N.A., Intracellular processing and transport of Junin virus glycoproteins influences virion infectivity (1994) Virus Res., 34, pp. 317-326 | ||
| 504 | |a Rice, W.G., Turpin, J.A., Huang, M., Azodicarbonamide inhibits HIV-1 replication by targeting the nucleocapsid protein (1997) Nat. Med., 3, pp. 341-345 | ||
| 504 | |a Goebel, F.-D., Hemmer, R., Schmit, J., Phase I/II dose escalation and randomized withdrawal study with add-on azodicarbonamide in patients failing on current antiretroviral therapy (2001) AIDS, 15, pp. 33-45 | ||
| 504 | |a Rice, W.G., Turpin, J.A., Schaeffer, C.A., Evaluation of selected chemotypes in coupled cellular and molecular target-based screens identifies novel HIV-1 zinc finger inhibitors (1996) J. Med. Chem., 39, pp. 3606-3616 | ||
| 504 | |a Rice, W.G., Baker, D.C., Schaeffer, C.A., Inhibition of multiple phases of human immunodeficiency virus type 1 replication by a dithiane compound that attacks the conserved zinc fingers of retroviral nucleocapsid proteins (1997) Antimicrob. Agents Chemother., 41, pp. 419-426 | ||
| 504 | |a Rossio, J.L., Esser, M.T., Suryanarayana, K., Inactivation of human immunodeficiency virus type 1 infectivity with preservation of conformational and functional integrity of virion surface proteins (1998) J. Virol., 72, pp. 7992-8001 | ||
| 504 | |a Turpin, J.A., Terpening, S.J., Schaeffer, C.A., Inhibitors of human immunodeficiency virus type 1 zinc fingers prevent normal processing of Gag precursors and result in the release of noninfectious virus particles (1996) J. Virol., 70, pp. 6180-6189 | ||
| 504 | |a Berthoux, L., Péchoux, C., Darlix, J.L., Multiple effects of an anti-human immunodeficiency virus nucleocapsid inhibitor on virus morphology and replication (1999) J. Virol., 73, pp. 10000-10009 | ||
| 504 | |a Salvato, M.S., Shimomaye, E.M., The completed sequence of lymphocytic chorio-meningitis virus reveals a unique RNA structure and a gene for a zinc finger protein (1989) Virology, 173, pp. 1-10 | ||
| 504 | |a Tortorici, M.A., Ghiringhelli, P.D., Lozano, M.E., Albarino, C.G., Romanowski, V., Zinc-binding properties of Junin virus nucleocapsid protein (2001) J. Gen. Virol., 82, pp. 121-128 | ||
| 504 | |a Garcin, D., Rochat, S., Kolakofsky, D., The Tacaribe arenavirus small zinc finger protein is required for both mRNA synthesis and genome replication (1993) J. Virol., 67, pp. 807-812 | ||
| 504 | |a Salvato, M.S., Molecular biology of the prototype arenavirus, lymphocytic choriomeningitis virus (1993) The Arenaviridae, pp. 133-156. , M.S. Salvato. New York: Plenum Press | ||
| 504 | |a Lee, K.J., Novella, I.S., Teng, M.N., Oldstone, M.B.A., De la Torre, J.C., NP and L proteins of lymphocytic choriomeningitis virus (LCMV) are sufficient for efficient transcription and replication of LCMV genomic RNA analogs (2000) J. Virol., 74, pp. 3470-3477 | ||
| 504 | |a López, N., Jácamo, R., Franze-Fernández, M.T., Transcription and RNA replication of Tacaribe virus genome and antigenome analogs require N and L proteins: Z protein is an inhibitor of these processes (2001) J. Virol., 75, pp. 12241-12251 | ||
| 520 | 3 | |a The action of five azo-based compounds against the arenaviruses Junin (JUNV) and Tacaribe (TCRV) was evaluated in vitro by a virus yield inhibition assay in Vero cells and a cell-free virion inactivation assay. The compound 2-azo-(1′-(2′-nitroso)naphthyl)-benzoate (ANNB) was the most effective inhibitor of arenavirus production in Vero cells with EC50 (effective concentration 50%) values in the range 6.5-26.2 μM and without inactivating properties. By contrast, the azodicarbonamide (ADA) was very effective in inactivating both arenaviruses with IC50 (inactivating concentration 50%) values of 7.6 and 5.3 μM against JUNV and TCRV, respectively. The virucidal activity of ADA was time- and temperature-dependent. ANNB had no inhibitory action on virus binding or penetration of target cells and did not affect the synthesis of viral proteins. The most likely event susceptible to ANNB would be the process of intracellular virion assembly. © 2002 Elsevier Science B.V. and International Society of Chemotherapy. All rights reserved. |l eng | |
| 536 | |a Detalles de la financiación: Agencia Nacional de Promoción Científica y Tecnológica | ||
| 536 | |a Detalles de la financiación: Ministerio de Salud de la Nación, MSAL | ||
| 536 | |a Detalles de la financiación: Consejo Nacional de Investigaciones Científicas y Técnicas | ||
| 536 | |a Detalles de la financiación: Council on Competitive Government | ||
| 536 | |a Detalles de la financiación: Consejo Nacional de Investigaciones Científicas y Técnicas | ||
| 536 | |a Detalles de la financiación: The authors acknowledge the National Cancer Institute, Frederick, USA, for providing the compounds. This work was supported by Consejo Nacional de Investigaciones Cientı́ficas y Técnicas (CONICET), Agencia Nacional de Promoción Cientı́fica y Tecnológica, y Subsecretarı́a de Investigación y Tecnologı́a, Ministerio de Salud, Argentina. EBD is member of the Research Career from CONICET and CCG is fellowship from CONICET. | ||
| 593 | |a Depto. de Quim. Biológica, Universidad de Buenos Aires, Ciudad Universitaria, Piso 4, Buenos Aires 1428, Argentina | ||
| 690 | 1 | 0 | |a ANTIVIRAL ACTIVITY |
| 690 | 1 | 0 | |a ARENAVIRUS |
| 690 | 1 | 0 | |a AZOIC COMPOUND |
| 690 | 1 | 0 | |a JUNIN VIRUS |
| 690 | 1 | 0 | |a TACARIBE VIRUS |
| 690 | 1 | 0 | |a VIRION INACTIVATION |
| 690 | 1 | 0 | |a 2 AZO[1' (2' NITROSO)NAPHTHYL]BENZOATE |
| 690 | 1 | 0 | |a ANTIVIRUS AGENT |
| 690 | 1 | 0 | |a AZO COMPOUND |
| 690 | 1 | 0 | |a AZOFORMAMIDE |
| 690 | 1 | 0 | |a BENZOIC ACID DERIVATIVE |
| 690 | 1 | 0 | |a CHEMICAL COMPOUND |
| 690 | 1 | 0 | |a UNCLASSIFIED DRUG |
| 690 | 1 | 0 | |a UREA DERIVATIVE |
| 690 | 1 | 0 | |a VIRUS PROTEIN |
| 690 | 1 | 0 | |a ARENAVIRUS |
| 690 | 1 | 0 | |a ARTICLE |
| 690 | 1 | 0 | |a CHRONOTHERAPY |
| 690 | 1 | 0 | |a DRUG ACTIVITY |
| 690 | 1 | 0 | |a DRUG EFFICACY |
| 690 | 1 | 0 | |a DRUG INHIBITION |
| 690 | 1 | 0 | |a DRUG MECHANISM |
| 690 | 1 | 0 | |a DRUG SENSITIVITY |
| 690 | 1 | 0 | |a EVALUATION |
| 690 | 1 | 0 | |a IC 50 |
| 690 | 1 | 0 | |a IN VITRO STUDY |
| 690 | 1 | 0 | |a INHIBITION KINETICS |
| 690 | 1 | 0 | |a NONHUMAN |
| 690 | 1 | 0 | |a PRIORITY JOURNAL |
| 690 | 1 | 0 | |a PROTEIN SYNTHESIS |
| 690 | 1 | 0 | |a TARGET CELL |
| 690 | 1 | 0 | |a TEMPERATURE DEPENDENCE |
| 690 | 1 | 0 | |a VERO CELL |
| 690 | 1 | 0 | |a VIRION |
| 690 | 1 | 0 | |a VIRUS ASSEMBLY |
| 690 | 1 | 0 | |a VIRUS INFECTION |
| 700 | 1 | |a Candurra, N.A. | |
| 700 | 1 | |a Damonte, E.B. | |
| 773 | 0 | |d Elsevier, 2003 |g v. 21 |h pp. 319-324 |k n. 4 |p Int. J. Antimicrob. Agents |x 09248579 |w (AR-BaUEN)CENRE-5213 |t International Journal of Antimicrobial Agents | |
| 856 | 4 | 1 | |u https://www.scopus.com/inward/record.uri?eid=2-s2.0-0037384516&doi=10.1016%2fS0924-8579%2802%2900390-4&partnerID=40&md5=535e79166326cab97fbf6297e7745a38 |y Registro en Scopus |
| 856 | 4 | 0 | |u https://doi.org/10.1016/S0924-8579(02)00390-4 |y DOI |
| 856 | 4 | 0 | |u https://hdl.handle.net/20.500.12110/paper_09248579_v21_n4_p319_Garcia |y Handle |
| 856 | 4 | 0 | |u https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_09248579_v21_n4_p319_Garcia |y Registro en la Biblioteca Digital |
| 961 | |a paper_09248579_v21_n4_p319_Garcia |b paper |c PE | ||
| 962 | |a info:eu-repo/semantics/article |a info:ar-repo/semantics/artículo |b info:eu-repo/semantics/publishedVersion | ||