Endocrine studies in ivermectin-treated heifers from birth to puberty

Continuous treatment with ivermectin from birth to puberty advanced sexual maturation by 3.7 wk in Holstein heifers grazing pastures naturally infected with nematodes. Every 14 d jugular blood samples were taken from birth to 45 wk of age from all heifers. No differences in serum FSH, estradiol, or...

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Autor principal: Lacau-Mengido, I.M
Otros Autores: Mejía, M.E, Díaz-Torga, G.S, Gonzalez Iglesias, A., Formía, N., Libertun, C., Becú-Villalobos, D.
Formato: Capítulo de libro
Lenguaje:Inglés
Publicado: American Society of Animal Science 2000
Acceso en línea:Registro en Scopus
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024 7 |2 scopus  |a 2-s2.0-0034169033 
024 7 |2 cas  |a Antinematodal Agents; Estradiol, 50-28-2; Follicle Stimulating Hormone, 9002-68-0; Insulin-Like Growth Factor I, 67763-96-6; Ivermectin, 70288-86-7; Luteinizing Hormone, 9002-67-9; Progesterone, 57-83-0; Thyroxine, 7488-70-2 
040 |a Scopus  |b spa  |c AR-BaUEN  |d AR-BaUEN 
100 1 |a Lacau-Mengido, I.M. 
245 1 0 |a Endocrine studies in ivermectin-treated heifers from birth to puberty 
260 |b American Society of Animal Science  |c 2000 
270 1 0 |m Lacau-Mengido, I.M.; Inst. de Biol. y Med. Experimental, CONICET, Obligado 2490, (1428) Buenos Aires, Argentina; email: ilacau@dna.uba.ar 
506 |2 openaire  |e Política editorial 
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504 |a Mejía, M.E., Libertun, C., Díaz-Torga, G.S., Villafañe, P., Formía, N., Becú-Villalobos, D., Lacau-Mengido, I.M., Continuous ivermectin treatment from birth to puberty on growth and reproduction in dairy heifers (1999) J. Anim. Sci., 77, pp. 1329-1334 
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520 3 |a Continuous treatment with ivermectin from birth to puberty advanced sexual maturation by 3.7 wk in Holstein heifers grazing pastures naturally infected with nematodes. Every 14 d jugular blood samples were taken from birth to 45 wk of age from all heifers. No differences in serum FSH, estradiol, or thyroxine levels were observed during the trial between the treated and untreated group. Mean LH levels were diminished in untreated heifers 4 wk before the first estrus and the amplitude of LH pulses was augmented in treated heifers when puberty was reached. Serum IGF-I levels increased from birth to 22 wk of age and then reached a plateau in both groups, but levels were consistently higher in treated heifers from 26 wk of age onward. Body weight gain was retarded in parasitized heifers and IGF-I values were positively correlated with body weight only during the first 20 wk of life. We suggest that enhanced prepubertal IGF-I levels in conjunction with increased prepubertal LH levels and pubertal LH pulse amplitude might be involved in the accelerated somatic maturation and in puberty advancement observed in ivermectin-treated heifers.  |l eng 
593 |a Inst. de Biol. y Med. Experimental, CONICET, Obligado 2490, (1428) Buenos Aires, Argentina 
593 |a Esc. MLMC Inchausti, Universidad de La Plata, 25 de Mayo, Valdés, (6667), Pcia. Bs.As, Argentina 
690 1 0 |a ESTRADIOL 
690 1 0 |a GONADOTROPINS 
690 1 0 |a HEIFERS 
690 1 0 |a INSULIN-LIKE GROWTH FACTOR 
690 1 0 |a IVERMECTIN 
690 1 0 |a PUBERTY 
690 1 0 |a ANTINEMATODAL AGENT 
690 1 0 |a ESTRADIOL 
690 1 0 |a FOLLITROPIN 
690 1 0 |a IVERMECTIN 
690 1 0 |a LUTEINIZING HORMONE 
690 1 0 |a PROGESTERONE 
690 1 0 |a SOMATOMEDIN C 
690 1 0 |a THYROXINE 
690 1 0 |a ANIMAL 
690 1 0 |a ANIMAL DISEASE 
690 1 0 |a ARTICLE 
690 1 0 |a BLOOD 
690 1 0 |a CATTLE 
690 1 0 |a DAIRYING 
690 1 0 |a DRUG EFFECT 
690 1 0 |a FEMALE 
690 1 0 |a GROWTH, DEVELOPMENT AND AGING 
690 1 0 |a METABOLISM 
690 1 0 |a PARASITE IDENTIFICATION 
690 1 0 |a RADIOIMMUNOASSAY 
690 1 0 |a SEXUAL MATURATION 
690 1 0 |a WEIGHT GAIN 
690 1 0 |a ANIMALS 
690 1 0 |a ANTINEMATODAL AGENTS 
690 1 0 |a CATTLE 
690 1 0 |a DAIRYING 
690 1 0 |a ESTRADIOL 
690 1 0 |a FEMALE 
690 1 0 |a FOLLICLE STIMULATING HORMONE 
690 1 0 |a INSULIN-LIKE GROWTH FACTOR I 
690 1 0 |a IVERMECTIN 
690 1 0 |a LUTEINIZING HORMONE 
690 1 0 |a PARASITE EGG COUNT 
690 1 0 |a PROGESTERONE 
690 1 0 |a RADIOIMMUNOASSAY 
690 1 0 |a SEXUAL MATURATION 
690 1 0 |a THYROXINE 
690 1 0 |a WEIGHT GAIN 
700 1 |a Mejía, M.E. 
700 1 |a Díaz-Torga, G.S. 
700 1 |a Gonzalez Iglesias, A. 
700 1 |a Formía, N. 
700 1 |a Libertun, C. 
700 1 |a Becú-Villalobos, D. 
773 0 |d American Society of Animal Science, 2000  |g v. 78  |h pp. 817-824  |k n. 4  |p J. Anim. Sci.  |x 00218812  |t Journal of Animal Science 
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