Cerebrovascular disease and gait disorders: Qualitative and quantitative analysis

Introduction and objective. Pyramidal gait impairment (GI) is a classical trait of cerebrovascular disease (CVD). To developed a method to quantify prospectively and transversely GI and disequilibrium, to be applied in the screening of pyramidal and non-pyramidal syndromes associated to different et...

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Autor principal: Domínguez, R.O
Otros Autores: Bartolomé, E.L, Serra, J.A, Marschoff, E.R, Famulari, A.L, D'Abbraccio, G.L, González, S.E, Bagg, E.
Formato: Capítulo de libro
Lenguaje:Español
Publicado: 2000
Acceso en línea:Registro en Scopus
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100 1 |a Domínguez, R.O. 
245 1 0 |a Cerebrovascular disease and gait disorders: Qualitative and quantitative analysis 
246 3 1 |a Enfermedad cerebrovascular y alteraciones de la marcha: Análisis cualitativo y cuantitativo 
260 |c 2000 
270 1 0 |m Domínguez, R.O.; Hospital Sirio-Libanés, Fundación Argentina Contra Las Enfermedades Neurológicas del Envejecimiento (FACENE), Güemes, 3440. 1.o C, Buenos Aires (1425), Argentina; email: dominguezraul@hotmail.com 
506 |2 openaire  |e Política editorial 
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504 |a Masdeu, J.C., Gorelick, P.B., Thalamic astasia: Inability to stand after unilateral thalamic lesions (1988) Ann Neurol, 23, pp. 596-598 
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504 |a Elble, R.J., Cousins, R., Leffler, K., Hughes, L., Gait initiation by patients with lower-half parkinsonism (1996) Brain, 119, pp. 1705-1707 
504 |a Masdeu, J.C., Wolfson, L., Lantos, G., Tobin, J.N., Grober, E., Whipple, R., Brain white-matter changes in the elderly prone to falling (1989) Arch Neurol, 46, pp. 1292-1293 
504 |a Jackson, H.J., (1932) Selected Writings of John Hughlings Jackson, 2. , Taylor J, Holmes G, Walshe, eds. London: Hodder and Stoughton 
504 |a Nutt, J.G., Marsden, C.D., Thompson, P.D., Human walking and higher-level gait disorders, particularly in the elderly (1993) Neurology, 43, pp. 268-272 
504 |a Marsden, C.D., Thompson, P.D., Frontal gait disorders (1996) Clinical Disorders of Balance Posture and Gait, pp. 188-192. , Bronstein AM, Brandt T, Woollacott M, eds. London: Arnold 
504 |a Adams, H.P., Bendixen, B.H., Kappelle, L.J., Biller, J., Love, B.B., Gordon, D.L., Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial (1993) Stroke, 24, pp. 35-41 
504 |a Roman, G., NINDS-AIREN International Work Shop Group: Vascular dementia. Diagnostic criteria for research studies (1993) Neurology, 43, pp. 250-260 
504 |a Folstein, M.F., Folstein, S.E., McHugh, P.R., Minimental State: A practical method for granding the cognitive state of patients for the clinician (1975) J Psychiatr Res, 12, pp. 189-198 
504 |a Domínguez, R., Envejecimiento y cerebro. Trastornos de la marcha y riesgo de caídas. Medicina (1998) Medicina, pp. 117-126. , Mautner B, ed. Buenos Aires: Fundación Favaloro 
504 |a Guimares, R.M., Isaacs, B., Characteristics of the gait in old people who fall (1980) Int Rehabil Med, 2, pp. 177-181 
504 |a Imms, F.J., Edholm, O.G., Studies of gait and mobility in the elderly (1981) Age Ageing, 10, pp. 147-151 
504 |a Sudarsky, L., Ronthal, M., Gait disorders among elderly patients: A survey study of 50 patients (1983) Arch Neurol, 40, pp. 740-744 
504 |a Saunders, J.B., Inman, V.T., Eberhart, H.D., The major determinants in normal and pathological gait (1953) J Bone Joint Surg, 35, pp. 543-547 
504 |a Lee, M.S., Marsden, C.D., Drop attacks (1996) Clinical Disorders of Balance Posture and Gait, pp. 177-185. , Bronstein AM, Brandt T, Woollacott M, eds. London: Arnold 
504 |a Thompson, P.D., Marsden, C.D., Gait disorder of subcortical arteriosclerotic encephalopathy: Binswanger's disease (1987) Mov Disord, 2, pp. 1-8 
504 |a Corral-Debrinski, M., Horton, T., Lott, M.T., Shoffner, J.M., Beal, M.F., Wallace, D.C., Mitochondrial DNA deletions in human brain: Regional variability and increase with advanced age (1992) Nat Genet, 2, pp. 324-329 
504 |a Mathias, S., Nayah, U., Isaacs, B., Balance in elderly patients: The Get-up and Go test (1986) Arch Phys Med Rehabil, 67, pp. 387-389 
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504 |a Bartolomé, E., Domínguez, R., Famulari, A., D'Abbraccio, G., González, S., Marcha anormal en el deterioro cognitivo asociado a lesión cerebrovascular (1996) Revista Neurológica Argentina, 21 (1 SUPPL.), p. 45 
520 3 |a Introduction and objective. Pyramidal gait impairment (GI) is a classical trait of cerebrovascular disease (CVD). To developed a method to quantify prospectively and transversely GI and disequilibrium, to be applied in the screening of pyramidal and non-pyramidal syndromes associated to different ethiological subtypes of CVD; using an Index of Gait and Equilibrium (IGE). Patients and methods. In constructing IGE, we used 14 equally weighted semiological variables: 6 measure balance, 6 gait, 1 sensitive abnormalities and 1 falls. Two neurologists separately examined each subject in the same day and repeating the evaluation after a week. Data analyses included Kruskal Wallis, χ2, Spearman correlations and Principal Components. Results. IGE was used in 90 subjects, 43 males, with a mean age of 70.6 years. 3 groups of people were formed: 1. CVD (A, 21 with silent vascular lesions diagnosed by imaging; B, 17 with vascular dementia; C, 21 with stroke); 2.13 subjects with cautious gait, not associated to any disease; and 3.18 normal control subjects (age 60-80 years). GI in the non-pyramidal syndrome were significantly related with small vessels disease (χ2= 16.37, dof= 1, p< 0.001). Conclusions. GI in CVD, pyramidal and non-pyramidal syndromes were equally frequent. Increased values of IGE caused by cautious gait in youngest non-stroke patients suggested high probability of silent CVD and significant association with small vessels disease. This preliminary assessment of IGE showed a reproducible and reliable tool for objectification and quantification of gait disorders. © 2000, Revista de Neurología.  |l eng 
593 |a Fundación Argentina Contra Las Enfermedades Neurológicas del Envejecimiento (FACENE), UBA, Buenos Aires, Argentina 
593 |a Facultad de Bioquímica Y Farmacia (CONICET), UBA, Buenos Aires, Argentina 
593 |a Cátedra de Biometría, Facultad de Ciencias Exactas, UBA, Buenos Aires, Argentina 
593 |a Hospital Sirio-Libanés, Fundación Argentina Contra Las Enfermedades Neurológicas del Envejecimiento (FACENE), Güemes, 3440. 1.o C, Buenos Aires (1425), Argentina 
690 1 0 |a CEREBROVASCULAR DISEASE 
690 1 0 |a GAIT DISORDERS 
690 1 0 |a INDEX OF GAIT AND EQUILIBRIUM 
690 1 0 |a LEUCOARAIOSIS 
690 1 0 |a SILENT BRAIN INFARCTS 
690 1 0 |a SMALL VESSELS DISEASE 
690 1 0 |a AGED 
690 1 0 |a ARTICLE 
690 1 0 |a BODY EQUILIBRIUM 
690 1 0 |a BRAIN 
690 1 0 |a BRAIN INFARCTION 
690 1 0 |a CROSS-SECTIONAL STUDY 
690 1 0 |a FEMALE 
690 1 0 |a GAIT 
690 1 0 |a HOSPITALIZATION 
690 1 0 |a HUMAN 
690 1 0 |a MALE 
690 1 0 |a MIDDLE AGED 
690 1 0 |a MOTOR DYSFUNCTION 
690 1 0 |a NEUROLOGIC EXAMINATION 
690 1 0 |a NUCLEAR MAGNETIC RESONANCE IMAGING 
690 1 0 |a PATHOLOGY 
690 1 0 |a PROSPECTIVE STUDY 
690 1 0 |a VASCULARIZATION 
690 1 0 |a AGED 
690 1 0 |a AGED, 80 AND OVER 
690 1 0 |a BRAIN 
690 1 0 |a CEREBRAL INFARCTION 
690 1 0 |a CROSS-SECTIONAL STUDIES 
690 1 0 |a FEMALE 
690 1 0 |a GAIT 
690 1 0 |a HUMANS 
690 1 0 |a MAGNETIC RESONANCE IMAGING 
690 1 0 |a MALE 
690 1 0 |a MIDDLE AGED 
690 1 0 |a MOVEMENT DISORDERS 
690 1 0 |a MUSCULOSKELETAL EQUILIBRIUM 
690 1 0 |a NEUROLOGIC EXAMINATION 
690 1 0 |a PROSPECTIVE STUDIES 
690 1 0 |a SEVERITY OF ILLNESS INDEX 
700 1 |a Bartolomé, E.L. 
700 1 |a Serra, J.A. 
700 1 |a Marschoff, E.R. 
700 1 |a Famulari, A.L. 
700 1 |a D'Abbraccio, G.L. 
700 1 |a González, S.E. 
700 1 |a Bagg, E. 
773 0 |d 2000  |g v. 31  |h pp. 1-8  |k n. 1  |p Rev. Neurol.  |x 02100010  |t Revista de Neurologia 
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