Effects of mGnRH on testicular steroidogenesis in the toad Bufo arenarum
GnRH controls vertebrate reproduction in several ways. This hormone not only affects the secretion of gonadotropins from the pituitary gland but also has a direct influence on several gonadal functions such as steroidogenesis, spermatogenesis, and spermiation. In the present paper we have studied th...
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Academic Press Inc.
2002
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| 005 | 20230518205153.0 | ||
| 008 | 190411s2002 xx ||||fo|||| 00| 0 eng|d | ||
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| 024 | 7 | |2 cas |a chorionic gonadotropin, 9002-61-3; cytochrome P450, 9035-51-2; gonadorelin, 33515-09-2, 9034-40-6; gonadotropin, 63231-54-9; protein, 67254-75-5 | |
| 040 | |a Scopus |b spa |c AR-BaUEN |d AR-BaUEN | ||
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| 100 | 1 | |a Canosa, L.F. | |
| 245 | 1 | 0 | |a Effects of mGnRH on testicular steroidogenesis in the toad Bufo arenarum |
| 260 | |b Academic Press Inc. |c 2002 | ||
| 270 | 1 | 0 | |m Ceballos, N.R.; Departamento de Ciencias Biologicas, F. Cie. Exactas y Nat./PRHOM-CONICET, Universidad de Buenos Aires, Pabellón 2, C1428EHA Buenos Aires, Argentina; email: nceballo@bg.fcen.uba.ar |
| 506 | |2 openaire |e Política editorial | ||
| 504 | |a Bahk, J.Y., Hyum, J.S., Chung, S.H., Lee, H., Kim, M.O., Lee, B.H., Choi, W.S., Stage specific identification of expression of GnRH mRNA and localization of the GnRH receptor in mature rat and adult human testis (1995) J. Urol., 154, pp. 1958-1961 | ||
| 504 | |a Battisti, A., Pierantoni, R., Vallarino, M., Trabucchi, M., Carnevali, O., Polzonetti-Magni, A.M., Fasano, S., Detection of GnRH molecular forms in brains and gonads of the crested newt, Triturus carnifex (1997) Peptides, 18, pp. 1029-1037 | ||
| 504 | |a Bélanger, A., Auclair, C., Seguin, C., Kelly, P.A., Labrie, F., Down-regulation of testicular androgen biosynthesis and LH receptor by an LHRH agonist: Role of prolactin (1979) Mol. Cell. Endocrinol., 13, pp. 47-53 | ||
| 504 | |a Bélanger, A., Cusan, L., Auclair, C., Seguin, C., Caron, S., Labrie, F., Effect of a LHRH agonist and hCG on testicular steroidogenesis in the adult rat (1980) Biol. Reprod., 22, pp. 1094-1101 | ||
| 504 | |a Bélanger, A., Labrie, F., Lemay, A., Caron, S., Raynaud, J.P., Inhibitory effects of a single intranasal administration of [D-Ser(TBU)6, des-Gly-NH210]LHRH ethylamide, a potent LHRH agonist, on serum steroid levels in normal adult men (1980) J. Steroid Biochem., 13, pp. 123-126 | ||
| 504 | |a Canosa, L.F., Ceballos, N.R., Effect of different steroidbiosynthesis inhibitors on the testicular steroidogenesis of the toad Bufo arenarum (2001) J. Comp. Physiol. (Part B), 171, pp. 519-526 | ||
| 504 | |a Canosa, L.F., Ceballos, N.R., Seasonal changes in pregnenolone metabolism in toad testis (2002) Gen. Comp. Endocrinol., 125, pp. 426-443 | ||
| 504 | |a Canosa, L.F., Ceballos, N.R., In vitro hCG and human recombinant FSH actions on testicular steroidogenesis in the toad Bufo arenarum (2002) Gen. Comp. Endocrinol., 126, pp. 318-324 | ||
| 504 | |a Canosa, L.F., Pozzi, A.G., Ceballos, N.R., Pregnenolone and Progesterone metabolism by testes of Bufo arenarum (1998) J. Comp. Physiol. (Part B), 168, pp. 491-496 | ||
| 504 | |a Carmichael, R., Bélanger, A., Cusan, L., Seguin, C., Caron, S., Labrie, F., Increased testicular 5-alpha-androstane-3 alpha, 17 beta-diol formation induced by treatment with [D-Ser (TBU) 6, des-Gly-NH2 (10)] LHRH ethylamide in the rat (1980) Steroids, 36, pp. 383-391 | ||
| 504 | |a Carolsfeld, J., Powell, J.F.F., Park, M., Fischer, W.H., Craig, A.G., Chang, J., Rivier, J.E., Sherwood, N.M., A novel form of gonadotropin-releasing hormone (GnRH) in herring sheds light on evolutionary pressures (2000) Endocrinology, 141, pp. 505-512 | ||
| 504 | |a Carriello, L., Romano, G., Spanuolo, A., Zanetti, L., Fasano, S., Minucci, S., Di Matteo, L., Chiffi, G., Molecular forms of immunoreactive gonadotropin-releasing hormone in hypothalamus and testis of the frog Rana esculenta (1989) Gen. Comp. Endocrinol., 75, pp. 343-348 | ||
| 504 | |a Chamson-Reig, A., Lux-Lantos, V., Tesone, M., Libertun, C., GnRH receptors and GnRH endocrine effects on luteoma cells (1997) Endocrine, 6, pp. 165-171 | ||
| 504 | |a D'Antonio, M., Fasano, S., De Leeuw, R., Pierantoni, R., Effects of gonadotropin-releasing hormone variants on plasma and testicular androgen levels in intact and hypophysectomized male frogs, Rana esculenta (1992) J. Exp. Zool., 261, pp. 34-39 | ||
| 504 | |a Di Mateo, L., Vallarino, M., Pierantoni, R., Localization of GnRH molecular forms in the brain, pituitary and testis of the frog, Rana esculenta (1996) J. Exp. Zool., 274, pp. 33-40 | ||
| 504 | |a Di Matteo, L., Minucci, S., Fasano, S., D'Antonio, M., Pierantoni, R., Chieffi, G., Indirect evidence for a physiological role exerted by a "testicular gonadotropin-releasing hormone" in the frog, Rana esculenta (1990) Gen. Comp. Endocrinol., 79, pp. 147-153 | ||
| 504 | |a Di Matteo, L., Minucci, S., Fasano, S., Pierantoni, R., Varriale, B., Chieffi, G., A gonadotropin-releasing hormone (GnRH) antagonist decreases androgen production and spermatogonial multiplication in frog (Rana esculenta): Indirect evidence for the existence of GnRH or GnRH-like material receptors in the hypophysis and testis (1988) Endocrinology, 122, pp. 62-67 | ||
| 504 | |a Dong, K.-W., Duval, P., Zeng, Z., Gordon, K., Willams, R.F., Hodgen, G.D., Jones, G., Roberts, J.L., Multiple transcription start sites for the GnRH gene in rhesus and cynomolgus monkeys: A non-human model for studying GnRH gene regulation (1996) Mol. Cell. Endocrinol., 117, pp. 121-130 | ||
| 504 | |a Fasano, S., D'Antonio, M., Chieffi, P., Cobellis, G., Pierantoni, R., Chicken GnRH-II and salmon GnRH effects on plasma and testicular androgen concentration in the male frog, Rana esculenta, during the annual reproductive cycle (1995) Comp. Biochem. Physiol. Part C: Pharmacol. Toxicol. Endocrinol., 112, pp. 79-86 | ||
| 504 | |a Fasano, S., De Leeuw, R., Pierantoni, R., Chieffi, G., Van Oordt, P.G., Characterization of gonadotropin-releasing hormone (GnRH) binding sites in the pituitary and testes of the frog, Rana esculenta (1990) Biochem. Biophys. Res. Commun., 168, pp. 923-932 | ||
| 504 | |a Gober, M.S., Myers, T.R., Marchaterre, M.A., Bass, A.H., Meyers, D.A., Structure, localization and molecular phylogeny of GnRH cDNA from paracanthopterygian fish, the painfin midshipman (Porichthys notatus) (1995) Gen. Comp. Endocrinol., 99, pp. 85-99 | ||
| 504 | |a Gobetti, A., Zerani, M., Mammalian GnRH involvement in prostaglandin F2α and sex steroid hormones testicular release in two amphibian species: The anuran water frog, Rana esculenta, and the urodele-crested newt, Triturus carnifex (1992) Gen. Comp. Endocrinol., 87, pp. 240-248 | ||
| 504 | |a Habibi, H.R., Andreu-Vieyra, C., Mirhadi, E., Functional significance of gonadal gonadotropin-releasing hormone (2001) Perspective in Comparative Endocrinology: Unity and Diversity, pp. 959-968. , Goos, H.J.Th., Rastogi, R.K., Vaudry, H., Pierantoni, R. (Eds.). Monduzzi Editore, Bologna, Italy | ||
| 504 | |a Habibi, H.R., Matsoukas, J.J.M., Gonadotropin-releasing hormone: Structural and functional diversity (1999) Bioactive Peptides in Drug Discovery and Design: Medical Aspects, , Matsoukas, J.J.M., Mavromoustakos, T. (Eds.). IOS Press | ||
| 504 | |a Habibi, H.R., Peter, R.E., Sokolowska, M., Rivier, J.E., Vale, W.W., Characterization of gonadotropin-releasing hormone (GnRH) binding to pituitary receptors in goldfish (Carassius auratus) (1987) Biol. Reprod., 36, pp. 844-853 | ||
| 504 | |a Hsueh, A.J., Jones, P.B., Extrapituitary actions of gonadotropin-releasing hormone (1981) Endocr. Rev., 2, pp. 437-461 | ||
| 504 | |a Jimenez-Liñan, M., Rubin, B., King, J.C., Examination of guinea pig luteinizing hormone-releasing hormone gene reveals a unique decapeptide and existence of tow transcripts in the brain (1997) Endocrinology, 138, pp. 4123-4137 | ||
| 504 | |a Karten, M.J., Rivier, R.P., Gonadotropin-releasing hormone analogue designs: Structure-function studies toward the development of agonists-rationale and perspective (1986) Endocr. Rev., 7, pp. 44-66 | ||
| 504 | |a King, J.A., Millar, R.P., Identification of His5-Trp7-Tyr8-GnRH (chicken GnRH II) in amphibian brain (1986) Peptides, 7, pp. 827-834 | ||
| 504 | |a King, J.A., Millar, R.P., Coordinate evolution of GnRHs and their receptors (1997) GnRH Neurons: Gene to Behavior, pp. 51-77. , Parhar, I., Sakuma, Y. (Eds.). Brain Shupan, Tokyo | ||
| 504 | |a King, J.A., Steneveld, A.A., Millar, R.P., Differential regional distribution of gonadotropin-releasing hormone in amphibian (clawed toad, Xenopus laevis) brain (1994) Reg. Peptides, 50, pp. 277-289 | ||
| 504 | |a Lin, X.-W., Peter, R.E., Expression of salmon gonadotropin-releasing hormone (GnRH) and chicken GnRHII precursor messenger ribonucleic acid in the brain and ovary of goldfish (1996) Gen. Cop. Endocrinol., 101, pp. 282-296 | ||
| 504 | |a Millar, R.P., Davidson, J.S., Flanagan, C., Illing, N., Becker, I., Jacobs, G., Wakefield, I., Sealfon, S.C., Gonadotropin-releasing hormone receptor structure and function (1994) Perspectives in Comparative Endocrinology: Proceedings of the XII International Congress of Comparative Endocrinology, pp. 264-268. , Davey, K.G., Peter, R.E., Tobe, S.S. (Eds.). National Research Council of Canada, Ottawa | ||
| 504 | |a Minucci, S., Di Mateo, L., Pierantoni, R., Varriale, B., Rastogi, R.K., Chieffi, G., In vivo and in vitro stimulatory effect of a gonadotropin-releasing hormone analogue (HOE 766) on spermatogonial multiplication in the frog, Rana esculenta (1986) Endocrinology, 119, pp. 731-736 | ||
| 504 | |a Minucci, S., Fasano, S., Pierantoni, R., Induction of S-phase entry by gonadotropin-releasing hormone agonist (buserelin) in the frog, Rana esculenta, primary spermatogonia (1996) Comp. Biochem. Physiol. Part C: Pharmacol. Toxicol. Endocrinol., 113, pp. 99-102 | ||
| 504 | |a Miranda, L.A., Paz, D.A., Affani, J.M., Somoza, G.M., Identification and neuroanatomical distribution of immunoreactivity for mammalian gonadotropin-releasing hormone (mGnRH) in the brain and neural hypophyseal lobe of the toad Bufo arenarum (1998) Cell. Tissue Res., 293, pp. 419-425 | ||
| 504 | |a Montaner, A.D., Park, M., Fischer, W.H., Craig, A.G., Chang, J.P., Somoza, G.M., Rivier, J.E., Sherwood, N.M., Primary structure of a novel gonadotropin-releasing hormone in the brain of a teleost, pejerrey (2001) Endocrinology, 142, pp. 1453-1460 | ||
| 504 | |a Oikawa, M., Dargen, C., Ny, T., Hsueh, A.J.W., Expression of gonadotropin-releasing hormone and prothymosin-messenger ribonucleic acid in the ovary (1990) Endocrinology, 127, pp. 2350-2356 | ||
| 504 | |a Pati, D., Habibi, H.R., Presence of salmon gonadotropin-releasing hormone (GnRH) and compounds with GnRH-like activity in the ovary of goldfish (1998) Endocrinology, 139, pp. 2015-2024 | ||
| 504 | |a Perrin, A., Chambaz, E.M., Defaye, G., Modulation of hydroxylase and lyase activities of bovine cytochrome P-45017α in adrenal and testicular microsomes by a tissue-specific local membrane environment (1995) J. Steroid Biochem. Mol. Biol., 54, pp. 121-129 | ||
| 504 | |a Pierantoni, R., Fasano, S., Di Mateo, L., Minucci, S., Varriale, B., Chieffi, G., Stimulatory effect of a GnRH agonist (buserelin) in in vivo and in vitro testosterone production by frog (Rana esculenta) testis (1984) Mol. Cell. Endocrinol., 38, pp. 215-219 | ||
| 504 | |a Pozzi, A.G., Lantos, C.P., Ceballos, N.R., Subcellular localization of 3-beta hydroxysteroid dehydrogenase isomerase in testis of Bufo arenarum H (1997) Gen. Comp. Endocrinol., 106, pp. 400-406 | ||
| 504 | |a Sherwood, N.M., Von Schalburg, K., Leschied, D.W., Origin and evolution of GnRH in vertebrates and invertebrates (1997) GnRH Neurons. Gene to Behavior, pp. 3-25. , Parhar, I.S., Sakuma, Y. (Eds.). Brain Shupan, Tokyo | ||
| 504 | |a Sherwood, N.M., Zoeller, R.T., Moore, F.R., Multiple forms of gonadotropin-releasing hormone in amphibian brain (1986) Gen. Comp. Endocrinol., 61, pp. 313-322 | ||
| 504 | |a Somoza, G.M., Paz, D.A., Stefano, A.V., Affanni, J.M., Identification of immunoreactive mammalian gonadotropin-releasing hormone in the brain of metamorphic larvae of Bufo arenarum Hensel (Amphibia: Anura) (1996) Int. J. Dev. Neurosci., 14, pp. 663-672 | ||
| 504 | |a Von Schalburg, K.R., Warby, C.M., Sherwood, N.M., Evidence of gonadotropin-releasing hormone peptides in the ovary and testis of rainbow trout (1999) Biol. Reprod., 60, pp. 1338-1344 | ||
| 504 | |a Wang, L., Bogerd, J., Choi, H.S., Seong, J.Y., Soh, J.M., Chun, S.Y., Blomenröhr, M., Kwon, H.B., Three distinct types of GnRH receptor characterized in the bullfrog (2001) Proc. Natl. Acad. Sci. USA, 98, pp. 361-366 | ||
| 504 | |a Wisner, J.R.J., Stalvey, J.R., Alteration in the normal pattern of serum testosterone and 5 alpha-androstane-3 alpha, 17 beta-diol in the immature male rat following chronic treatment with luteinizing hormone releasing hormone or luteinizing hormone (1980) Steroids, 36, pp. 337-348 | ||
| 504 | |a Wright, R.S., A reagent for the non-destructive location of steroids and some other lipophilic materials on silica gel thin layer chromatograms (1971) J. Chromatogr., 59, pp. 220-221 | ||
| 504 | |a Yoo, M.S., Kang, H.M., Choi, H.S., Chun, S.Y., Troskie, B., Millar, R.P., Kwon, H.G., Molecular cloning, distribution and pharmacological characterization of a novel gonadotropin-releasing hormone ([Trp8]GnRH) in frog brain (2000) Mol. Cell. Endocrinol., 164, pp. 197-204 | ||
| 520 | 3 | |a GnRH controls vertebrate reproduction in several ways. This hormone not only affects the secretion of gonadotropins from the pituitary gland but also has a direct influence on several gonadal functions such as steroidogenesis, spermatogenesis, and spermiation. In the present paper we have studied the in vitro effects of GnRH on the testicular steroidogenesis of Bufo arenarum to ascertain the role of this peptide in the control of the steroidogenic pathway previously described in this species. It was found that GnRH is able to reduce basal as well as hCG-stimulated testosterone release, having an inhibitory effect on P450c17 activity. Thus, GnRH could be involved in the mechanism that regulates the metabolic change in the testicular steroidogenesis. Additionally, testicular GnRH binding site has been characterised, showing a Kd of 34 nM and a maximum binding of 4.7 pmol/mg protein. © 2002 Elsevier Science (USA). All rights reserved. |l eng | |
| 536 | |a Detalles de la financiación: Universidad de Buenos Aires | ||
| 536 | |a Detalles de la financiación: National Council for Scientific Research | ||
| 536 | |a Detalles de la financiación: Consejo Nacional de Investigaciones Científicas y Técnicas | ||
| 536 | |a Detalles de la financiación: This work was supported by grants from the National Research Council of Argentina (CONICET) to the “Programa de Regulación Hormonal y Metabólica” (PRHOM), and the University of Buenos Aires. The authors wish to thank Dr. Carlos P. Lantos for the critical revision of the manuscript. The authors also thank Elea Lab. (Argentina), for the supply of hCG and Dr Damasia Becú-Villalobos (IByME-CONICET) for providing Buserelin. | ||
| 593 | |a Laboratorio De Endocrinología Comparada, Departamento De Ciencias Biológicas, Universidad De Buenos Aires, C1428EHA Buenos Aires, Argentina | ||
| 593 | |a Instituto Tecnológico De Chascomús, IIB/INTECH (CONICET-Universidad De San Martín), Provincia de Buenos Aires, Argentina | ||
| 690 | 1 | 0 | |a AMPHIBIAN-TESTIS |
| 690 | 1 | 0 | |a GNRH-RECEPTOR |
| 690 | 1 | 0 | |a GONADOTROPIN-RELEASING HORMONE |
| 690 | 1 | 0 | |a STEROIDOGENESIS |
| 690 | 1 | 0 | |a STEROIDOGENIC-ENZYME |
| 690 | 1 | 0 | |a TOAD |
| 690 | 1 | 0 | |a CHORIONIC GONADOTROPIN |
| 690 | 1 | 0 | |a CYTOCHROME P450 |
| 690 | 1 | 0 | |a GONADORELIN |
| 690 | 1 | 0 | |a GONADOTROPIN |
| 690 | 1 | 0 | |a PROTEIN |
| 690 | 1 | 0 | |a ANIMAL TISSUE |
| 690 | 1 | 0 | |a ARTICLE |
| 690 | 1 | 0 | |a BINDING SITE |
| 690 | 1 | 0 | |a CONTROLLED STUDY |
| 690 | 1 | 0 | |a ENZYME ACTIVITY |
| 690 | 1 | 0 | |a HORMONE ACTION |
| 690 | 1 | 0 | |a HORMONE BINDING |
| 690 | 1 | 0 | |a HORMONE RELEASE |
| 690 | 1 | 0 | |a IN VITRO STUDY |
| 690 | 1 | 0 | |a MALE |
| 690 | 1 | 0 | |a NONHUMAN |
| 690 | 1 | 0 | |a PRIORITY JOURNAL |
| 690 | 1 | 0 | |a PROTEIN BINDING |
| 690 | 1 | 0 | |a REGULATORY MECHANISM |
| 690 | 1 | 0 | |a STEROIDOGENESIS |
| 690 | 1 | 0 | |a TESTIS |
| 690 | 1 | 0 | |a TESTOSTERONE RELEASE |
| 690 | 1 | 0 | |a TOAD |
| 700 | 1 | |a Pozzi, A.G. | |
| 700 | 1 | |a Somoza, G.M. | |
| 700 | 1 | |a Ceballos, N.R. | |
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