Quantitation of polyamines in hypothalamus and pituitary of female and male developing rats
The quantitation of four polyamines in hypothalamus and pituitary is studied in male and female developing rats using an improved high-performance liquid chromatography method. In the hypothalamus, putrescine (PUT) reaches the highest concentration (nmol/mg protein) on day 6. It shows the lowest val...
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| Formato: | Capítulo de libro |
| Lenguaje: | Inglés |
| Publicado: |
Elsevier Ireland Ltd
2002
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| Acceso en línea: | Registro en Scopus DOI Handle Registro en la Biblioteca Digital |
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| LEADER | 08806caa a22009857a 4500 | ||
|---|---|---|---|
| 001 | PAPER-20382 | ||
| 003 | AR-BaUEN | ||
| 005 | 20230518205147.0 | ||
| 008 | 190411s2002 xx ||||fo|||| 00| 0 eng|d | ||
| 024 | 7 | |2 scopus |a 2-s2.0-0037134113 | |
| 024 | 7 | |2 cas |a agmatine, 306-60-5; eflornithine, 67037-37-0, 70052-12-9; putrescine, 110-60-1, 333-93-7; spermidine, 124-20-9, 334-50-9 | |
| 040 | |a Scopus |b spa |c AR-BaUEN |d AR-BaUEN | ||
| 030 | |a NELED | ||
| 100 | 1 | |a Thyssen, S.M. | |
| 245 | 1 | 0 | |a Quantitation of polyamines in hypothalamus and pituitary of female and male developing rats |
| 260 | |b Elsevier Ireland Ltd |c 2002 | ||
| 270 | 1 | 0 | |m Libertun, C.; Laboratorio de Neuroendocrinologia, Inst. de Biol. y Med. Exp.-CONICET, Vuelta de Obligado 2490, 1428 Buenos Aires, Argentina; email: libertun@dna.uba.ar |
| 506 | |2 openaire |e Política editorial | ||
| 504 | |a Contestabile, A., Facchinetti, F., Ciani, E., Sparapani, M., Virgili, M., Chronic neonatal blockade of NMDA receptor does not affect developmental polyamine metabolism but results in altered response to the excitotoxic induction of ornithine decarboxylase (1994) Neurochem. Int., 24, pp. 549-554 | ||
| 504 | |a Flores, H.E., Galston, A.W., Analysis of polyamines in higher plants by high performance liquid chromatography (1982) Plant Physiol., 69, pp. 701-706 | ||
| 504 | |a Gilad, G.M., Gilad, V.H., Polyamine uptake, binding and release in rat brain (1991) Eur. J. Pharmacol., 193, pp. 41-46 | ||
| 504 | |a Gilad, G.M., Dornay, M., Gilad, V.H., Polyamines induce precocious development in rats. Possible interaction with growth factors (1989) Int. J. Dev. Neurosci., 7, pp. 641-653 | ||
| 504 | |a He, Y., Suziki, T., Kashiwagi, K., Igarashi, K., Antizyme delays the restoration of growth of polyamine-deficient cells through its negative regulation of polyamine transport (1994) Biochem. Biophys. Res. Commun., 203, pp. 608-614 | ||
| 504 | |a Hockl, P.F., Thyssen, S.M., Libertun, C., An improved HPLC method for identification and quantitation of polyamines and related compounds as benzoylated derivatives (2000) J. Liq. Chromatogr. Rel. Technol., 23, pp. 693-703 | ||
| 504 | |a Khan, N.A., Quemener, V., Moulinoux, J.P., Polyamine membrane transport regulation (1991) Cell Biol. Int. Rep., 15, pp. 9-24 | ||
| 504 | |a Li, G., Regunathan, S., Barrow, C.J., Eshraghi, J., Cooper, R., Reis, D.J., Agmatine: An endogenous clonidine-displacing substance in the brain (1994) Science, 263, pp. 966-969 | ||
| 504 | |a Lowry, O.H., Rosebrough, N.H., Farr, A.L., Randall, R.J., Protein measurement with Folin phenol reagent (1951) J. Biol. Chem., 193, pp. 265-275 | ||
| 504 | |a Morgan, D.M.L., (1998) Polyamine Protocols, pp. 1-186. , Humana Press, Totowa, NJ | ||
| 504 | |a Morrison, L.D., Becker, L., Ang, L.C., Kish, S.J., Polyamines in human brain: Regional distribution and influence of aging (1995) J. Neurochem., 65, pp. 636-642 | ||
| 504 | |a Najm, I., Vanderklish, P., Lynch, G., Baudry, M., Effect of treatment with α-difluoromethylornithine on polyamine and spectrin breakdown levels in neonatal rat brain (1991) Dev. Brain Res., 63, pp. 287-289 | ||
| 504 | |a Pegg, A.E., Recent advances in the biochemistry of polyamines in eukaryotes (1986) Biochem. J., 234, pp. 249-262 | ||
| 504 | |a Sastre, M., Regunathan, S., Galea, E., Reis, D.J., Agmatinase activity in rat brain: A metabolic pathway for the degradation of agmatine (1996) J. Neurochem., 67, pp. 1761-1765 | ||
| 504 | |a Scalabrino, G., Lorenzini, E.C., Polyamines and mammalian hormones. Part II: Paracrine signals and intracellular regulators (1991) Mol. Cell. Endocrinol., 77, pp. 37-56 | ||
| 504 | |a Scalabrino, G., Lorenzini, E.C., Ferioli, M.E., Polyamines and mammalian hormones. Part I: Biosynthesis, interconversion and hormone effects (1991) Mol. Cell. Endocrinol., 77, pp. 1-35 | ||
| 504 | |a Seiler, N., Pharmacological properties of the natural polyamines and their depletion by biosynthesis inhibitors as a therapeutic approach (1991) Prog. Drug Res., 37, pp. 107-160 | ||
| 504 | |a Sltokin, T.A., Bartolome, J., Role of ornithine decarboxylase and the polyamines in nervous system development: A review (1986) Brain Res. Bull., 17, pp. 307-320 | ||
| 504 | |a Thyssen, S.M., Libertun, C., α-Difluoromethylornithine modifies FSH secretion and puberty onset in the female rat (1996) Proc. Soc. Exp. Biol. Med., 211, pp. 76-80 | ||
| 504 | |a Thyssen, S.M., Becu-Villalobos, D., Lacau-Mengido, I.M., Libertun, C., α-Difluoromethylornithine modifies gonadotropin-releasing hormone release and follicle-stimulating hormone secretion in the immature female rat (1997) Proc. Soc. Exp. Biol. Med., 215, pp. 192-197 | ||
| 520 | 3 | |a The quantitation of four polyamines in hypothalamus and pituitary is studied in male and female developing rats using an improved high-performance liquid chromatography method. In the hypothalamus, putrescine (PUT) reaches the highest concentration (nmol/mg protein) on day 6. It shows the lowest value in comparison with any other polyamine. Spermidine (SPD) is high during the first postnatal days. Spermine (SPM) fluctuates, and agmatine (AGM) is highest during the first week. SPD, SPM and AGM are lower in females. In the pituitary, PUT, SPD and AGM are high during the first week. SPM remains constant and it is higher in males. AGM is higher in males only on day 1. PUT shows the lowest concentration of all. Concentrations of PUT, SPD and SPM are higher in the pituitary; AGM is higher in the hypothalamus. α-Difluoromethylornithine (a specific and irreversible inhibitor of ornithine decarboxylase) decreases PUT and SPD, increased SPM and AGM remain unchanged in the hypothalamus and pituitary. Thus, each polyamine has its own pattern in hypothalamus and in pituitary during development in males and females; these changes could be related to the hypothalamic control of pituitary secretion of hormones related to reproduction in mammals. © 2002 Elsevier Science Ireland Ltd. All rights reserved. |l eng | |
| 536 | |a Detalles de la financiación: Agencia Nacional de Promoción Científica y Tecnológica, BID 802 OC AR PICT 0043 | ||
| 536 | |a Detalles de la financiación: Consejo Nacional de Investigaciones Científicas y Técnicas | ||
| 536 | |a Detalles de la financiación: Universidad de Buenos Aires | ||
| 536 | |a Detalles de la financiación: This work was supported by grants from Consejo Nacional de Investigaciones Cientı́ficas y Técnicas (CONICET), Agencia Nacional de Promoción Cientı́fica y Tecnológica (ANPCyT; BID 802 OC AR PICT 0043), Universidad de Buenos Aires and Ministerio de Salud Pública, Argentina. | ||
| 593 | |a Laboratorio de Neuroendocrinología, Instituto de Biología y Medicina Experimental-CONICET, Buenos Aires, Argentina | ||
| 593 | |a Department of Physiology, University of Buenos Aires Medical School, Buenos Aires, Argentina | ||
| 593 | |a Laboratorio de Neuroendocrinolog, Instituto de Biologa y Medicina Experimental-CONICET, Vuelta de Obligado 2490, 1428 Buenos Aires, Argentina | ||
| 690 | 1 | 0 | |a DEVELOPMENT |
| 690 | 1 | 0 | |a HYPOTHALAMUS |
| 690 | 1 | 0 | |a PITUITARY |
| 690 | 1 | 0 | |a POLYAMINES |
| 690 | 1 | 0 | |a RAT |
| 690 | 1 | 0 | |a SEXES |
| 690 | 1 | 0 | |a Α-DIFLUOROMETHYLORNITHINE |
| 690 | 1 | 0 | |a AGMATINE |
| 690 | 1 | 0 | |a EFLORNITHINE |
| 690 | 1 | 0 | |a ORNITHINE DECARBOXYLASE INHIBITOR |
| 690 | 1 | 0 | |a POLYAMINE DERIVATIVE |
| 690 | 1 | 0 | |a PUTRESCINE |
| 690 | 1 | 0 | |a SPERMIDINE |
| 690 | 1 | 0 | |a ANIMAL EXPERIMENT |
| 690 | 1 | 0 | |a ARTICLE |
| 690 | 1 | 0 | |a CONTROLLED STUDY |
| 690 | 1 | 0 | |a DIAGNOSTIC VALUE |
| 690 | 1 | 0 | |a DOSE RESPONSE |
| 690 | 1 | 0 | |a FEMALE |
| 690 | 1 | 0 | |a HIGH PERFORMANCE LIQUID CHROMATOGRAPHY |
| 690 | 1 | 0 | |a HYPOPHYSIS |
| 690 | 1 | 0 | |a HYPOPHYSIS FUNCTION |
| 690 | 1 | 0 | |a HYPOTHALAMUS |
| 690 | 1 | 0 | |a MALE |
| 690 | 1 | 0 | |a MAMMAL |
| 690 | 1 | 0 | |a NONHUMAN |
| 690 | 1 | 0 | |a PERINATAL PERIOD |
| 690 | 1 | 0 | |a PRIORITY JOURNAL |
| 690 | 1 | 0 | |a QUANTITATIVE ANALYSIS |
| 690 | 1 | 0 | |a RAT |
| 690 | 1 | 0 | |a REPRODUCTION |
| 700 | 1 | |a Libertun, C. | |
| 773 | 0 | |d Elsevier Ireland Ltd, 2002 |g v. 323 |h pp. 65-69 |k n. 1 |p Neurosci. Lett. |x 03043940 |w (AR-BaUEN)CENRE-6277 |t Neuroscience Letters | |
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| 856 | 4 | 0 | |u https://hdl.handle.net/20.500.12110/paper_03043940_v323_n1_p65_Thyssen |y Handle |
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