Atypical association of H1 and H2 histamine receptors with signal transduction pathways during multistage mouse skin carcinogenesis
Objective: In the present work we studied the association of histamine receptors with second messengers during multistage carcinogenesis in Sencar mice skin. Methods: 96 Sencar female mouse, divided into six groups were used. Tumors appeared only in the 7,12-dimethyl-benz[a]anthracene-initiated and...
Guardado en:
| Autor principal: | |
|---|---|
| Otros Autores: | , , , , , , |
| Formato: | Capítulo de libro |
| Lenguaje: | Inglés |
| Publicado: |
1997
|
| Acceso en línea: | Registro en Scopus DOI Handle Registro en la Biblioteca Digital |
| Aporte de: | Registro referencial: Solicitar el recurso aquí |
| LEADER | 14235caa a22017297a 4500 | ||
|---|---|---|---|
| 001 | PAPER-20172 | ||
| 003 | AR-BaUEN | ||
| 005 | 20230518205134.0 | ||
| 008 | 190411s1997 xx ||||fo|||| 00| 0 eng|d | ||
| 024 | 7 | |2 scopus |a 2-s2.0-0030612654 | |
| 024 | 7 | |2 cas |a 7,12 dimethylbenz[a]anthracene, 57-97-6; acetone, 67-64-1; cyclic AMP, 60-92-4; histamine, 51-45-6, 56-92-8, 93443-21-1; inositol phosphate, 15421-51-9; phorbol 13 acetate 12 myristate, 16561-29-8; 9,10-Dimethyl-1,2-benzanthracene, 57-97-6; Cimetidine, 51481-61-9; Cyclic AMP, 60-92-4; Histamine H1 Antagonists; Histamine H2 Antagonists; Phosphatidylinositols; Pyrilamine, 91-84-9; Receptors, Histamine H1; Receptors, Histamine H2; Tetradecanoylphorbol Acetate, 16561-29-8; tiotidine, 69014-14-8 | |
| 040 | |a Scopus |b spa |c AR-BaUEN |d AR-BaUEN | ||
| 030 | |a INREF | ||
| 100 | 1 | |a Fitzsimons, C. | |
| 245 | 1 | 0 | |a Atypical association of H1 and H2 histamine receptors with signal transduction pathways during multistage mouse skin carcinogenesis |
| 260 | |c 1997 | ||
| 270 | 1 | 0 | |m Rivera, E.; Laboratorio de Radioisotopos, Facultad de Farmacia y Bioquimica, Universidad de Buenos Aires, Junin 956, 1113 Buenos Aires, Argentina; email: rivera@labrad.uba.ar |
| 506 | |2 openaire |e Política editorial | ||
| 504 | |a Slaga, T.J., Mechanisms involved in two-stage carcinogenesis in mouse skin (1984) Mechanisms of Tumor Promotion, Tumour Promotion and Skin Carcinogenesis, 2, pp. 1-16. , Slaga TJ, editor. Boca Raton: CRC Press | ||
| 504 | |a Tilly, B.C., Tertoolen, L.G., Remorie, R., Ladoux, A., Verlaan, I., De Laat, S.W., Histamine as a growth factor and chemoattraetant for human carcinoma and melanoma cells: Action through Ca2+ mobilizing H1 receptors (1990) J Cell Biol, 11, pp. 1211-1215 | ||
| 504 | |a Davio, C., Baldi, A., Mladovan, A., Cricco, G., Fitzsimons, C., Bergoc, R., Expression of histamine receptors in different cell lines derived from mammary gland and human breast carcinomas (1995) Inflamm Res, 44 (1 SUPPL.), pp. 70-71 | ||
| 504 | |a Fischer, S., Patrick, K.E., Patamalai, B., Slaga, T.J., Effects of antihistamines on phorbol ester tumor promotion and vascular permeability changes (1990) Carcinogenesis, 11, pp. 991-996 | ||
| 504 | |a Ash, A.S.F., Schild, H.V., Receptors mediating some actions of histamine (1986) Br J Pharmacol Chemother, 27, pp. 427-439 | ||
| 504 | |a Hill, S.J., Distribution, properties, and functional characteristics of three classes of histamine receptor (1990) Pharm Rev, 42, pp. 45-83 | ||
| 504 | |a Leurs, R., Smit, M.J., Timmerman, H., Molecular pharmacological aspects of histamine receptors (1995) Pharmacol Ther, 66, pp. 413-463 | ||
| 504 | |a Mitsuhashi, M., Payan, D.G., Functional diversity of histamine and histamine receptors (1992) J Invest Dermatol, 98, pp. 85-111 | ||
| 504 | |a Davio, C., Cricco, G., Bergoc, R., Rivera, E., H1 and H2 histamine receptors in experimental carcinomas with an atypical coupling to signal transducers (1995) Biochem Pharmacol, 50, pp. 91-96 | ||
| 504 | |a Cricco, G., Davio, C.A., Fitzsimons, C.P., Engel, N., Bergoc, R.M., Rivera, E.S., Hislamine as an autocrine growth factor in experimental carcinomas (1994) Agents Actions, 43, pp. 17-20 | ||
| 504 | |a Aldaz, C.M., Conti, C.J., Giménev, I.B., Slaga, T.J., Klein-Szanto, A.J.P., Cutaneous changes during prolonged application of 12-O-tetradecanoyl-phorbol-13-acetate on mouse skin and residual effects after cessation of treatment (1985) Cancer Res, 45, pp. 2753-2759 | ||
| 504 | |a Norrby, K., Intradermal mast-cell secretion causing cutaneous mitogenesis (1983) Virchows Arch Abt B Zellpath, 42, pp. 263-269 | ||
| 504 | |a Leschke, C., Elz, S., Garbarg, M., Schunack, W., Synthesis and H1 receptor agonist activity of a series of 2-phenylhistamine. 2-heteroarylhistamines and analogues (1995) J Med Chem, 38, pp. 1287-1294 | ||
| 504 | |a Parsons, M.E., Owen, D.A., Ganellin, C.R., Durant, G.J., Dimaprit(S3-(N,N-dimethylamino)propylisothiourea) - A highly specific histamine H2-receptor agonist. Part I, Pharmacology (1977) Agents Actions, 7, pp. 31-37 | ||
| 504 | |a Freter, C.E., Lippman, M.E., Cheville, A., Zinn, S., Gelmann, E.P., Alterations in phosphoinositide metabolism associated with 17β-estradiol and growth factor treatment of MCF-7 breast cancer cells (1988) Mol Endocrinol, 2, pp. 159-166 | ||
| 504 | |a Enerbäck, L., Mast cells in rat gastrointestinal mucosa II: Dye binding and metachromatic properties (1966) Acta Pathol Microbiol Scand, 66, pp. 303-312 | ||
| 504 | |a Kitamura, Y., Taguchi, T., Yokoyama, M., Tamai, M., Yamatodani, A., Watanabe, T., Increase in histidine decarboxylase activity in mouse skin after application of tumor promoters (1984) Cellular Interactions by Environmental Tumor Promoters, pp. 327-334. , Fuyiki et al. editors. Japan Sci Soc Press, Tokyo | ||
| 504 | |a Watanabe, T., Taguchi, Y., Sasaki, K., Tsuyama, K., Kitamura, Y., Increases of histidine decarboxylase activity in mouse skin after application of the tumor promoter tetradecanoyl phorbol acetate (1981) Biochem Biophys Res Commun, 100, pp. 427-432 | ||
| 504 | |a Malaviya, K., Morrison, A.R., Pentlamol, A.P., Histamine in human epidermal cells is induced by ultraviolet light injury (1996) J Invest Dermatol, 1106, pp. 785-789 | ||
| 504 | |a Engel, N., Cricco, G., Davio, C., Martin, G., Croci, M., Fitzsimons, C., Histamine regulates the expression of histidine decabroxylase in N-nitroso-N-methylurca (NMU)-induced mammary tumors in rats (1996) Inflamm Res, 45 (1 SUPPL.), pp. S64-5 | ||
| 504 | |a Davio, C., Martin, G., Cricco, G., Fitzsimons, C., Bergoc, R., Rivera, E., Role of histamine on growth and differentiation of the rat mammary gland (1994) Agents Actions, 41, pp. 115-117 | ||
| 504 | |a Lemos, B., Davio, C., Gass, H., Gonzalez, P., Cricco, G., Martin, G., Histamine receptors in human mammary gland, different benign lesions and mammary carcinomas (1995) Inflamm Res, 44 (1 SUPPL.), pp. 68-69 | ||
| 504 | |a Fiore-Donati, L., Debenedictis, G., Chieco-Bianchi, L., Development of mast cell reaction during chemical skin carcinogenesis of mouse (1962) Nature (Lond), 193, pp. 287-293 | ||
| 504 | |a Saiti, H., Sanai, Y., Nakamura, H., Watanabe, N., Ito, T., Nagai, Y., Enhancement of clonal proliferation of mouse mast cells by tumor-promoting phorbol ester (1984) Cancer Res, 44, pp. 2110-2114 | ||
| 504 | |a De Rey, B.M., Palmieri, M.A., Durán, H.A., Mast cell phenotypic changes in skin of mice during benzoyl peroxide-induced tumor promotion (1994) Tumor Biol, 15, pp. 166-174 | ||
| 504 | |a Mitsuhashi, M., Mitsuhashi, T., Payan, D.G., Multiple signalling pathways of histamine H2 receptors (1989) J Biol Chem, 264, pp. 18356-18362 | ||
| 504 | |a Klinker, S.F., Wenzelseifert, K., Seifert, R., G-protcin-coupled receptors in HL-60 human leukemia cells (1996) Gen Pharmacol, 27, pp. 33-54 | ||
| 504 | |a Nishizuka, Y., The role of protein kinase C in cell surface signal transduction and tumor promotion (1984) Nature, 308, pp. 693-698 | ||
| 504 | |a Marks, F., Gschwendt, M., Protein kinase C and skin tumor promotion (1995) Mutation Res, 333, pp. 161-172 | ||
| 504 | |a Stabel, S., Parker, P.J., Protein kinase C (1991) Pharmacol Ther, 51, pp. 71-95 | ||
| 504 | |a Fleischman, L.F., Chahwala, S.B., Cantley, L., Ras-transformed cells: Altered levels of phosphatidylinositol 4,5 biphosphates and catabolites (1986) Science, 231, pp. 407-410 | ||
| 504 | |a Vintermyr, O.K., Bøe, R., Brustugon, O.T., Maronde, E., Aakuaag, A., Døskeland, S.O., Cyclic adenosine monophosphate analogs 8-Cl-and 8-NH2cAMP induce cell death independently of cAMP kinase-mediated inhibition of the G1/S transition in mammary carcinoma cells (1995) Endocrinology, 136, pp. 2513-2519 | ||
| 504 | |a Quintanilla, M., Brown, K., Ramsden, M., Baimain, A., Carcinogen specific mutation and amplification of Ha-ras during mouse skin carcinogenesis (1986) Nature, 322, pp. 78-80 | ||
| 504 | |a Zarbl, H., Sukumur, S., Arthur, A., Martin-Zanca, D., Barbacid, M., Direct mutagenesis of Ha-ras-1 oncogenes by N-nitroso-N-methylurea during initiation of mammary carcinogenesis in rats (1985) Nature, 315, pp. 382-385 | ||
| 504 | |a Blackmore, P.F., Oakes, S.G., Somers, K.D., Altered H, histamine receptor signaling in Balb/3T3 cells transformed by v-K-ras and v-H-ras oncogenes (1992) Oncogene, 7, pp. 2053-2057 | ||
| 504 | |a Kenakim, T., Agonist-receptor efficacy II: Agonist trafficking of receptors signals (1995) TIPS, 16, pp. 232-238 | ||
| 504 | |a Orange, P.R., Heath, P.R., Wright, S.R., Pearson, R.C.A., Allclic variation of the human histamine H2 receptor gene (1996) NeuroReport, 7, pp. 1293-1296 | ||
| 504 | |a Burde, R., Seifert, R., Stimulation of hislamine H2- (and H1)-receptors activates Ca2+ influx in all-trans-retinoic acid-differentiated HL-60 cells independently of phospholipase C or adenylyl cyclase (1996) Naunyn-Schmiedeberg's Arch Pharmacol, 353, pp. 123-129 | ||
| 520 | 3 | |a Objective: In the present work we studied the association of histamine receptors with second messengers during multistage carcinogenesis in Sencar mice skin. Methods: 96 Sencar female mouse, divided into six groups were used. Tumors appeared only in the 7,12-dimethyl-benz[a]anthracene-initiated and 12-O-tetradecanoylphorbol-13-acetate-promoted group. Control groups received only TPA, or acetone or no treatment at all. Periodically during the promotion period, cAMP and inositol phosphate production were measured after stimulation with H1 or H2 agonists in samples from all groups. Results: In non-treated skin, H1 receptors were coupled to phosphatidylinositol hydrolysis and H2 receptors mediated cAMP production. Conversely, in tumors H2 receptors were associated with phosphatidylinositol hydrolysis and H1 mediated a rise in cAMP levels. The skin among tumors and the skin from all control groups maintained the same coupling as non-treated skin. An increase in mast cell number, with a homogeneous subepithelial distribution and marked phenotypic changes, was also observed in promoted skin. Conclusions: These findings indicate an atypical association of histamine receptors with second messengers that could be a critical feature for the postulated action of histamine in tumor growth. |l eng | |
| 536 | |a Detalles de la financiación: Universidad de Buenos Aires, FA005 | ||
| 536 | |a Detalles de la financiación: Consejo Nacional de Investigaciones Científicas y Técnicas, 0082/92 | ||
| 536 | |a Detalles de la financiación: Acknowledgments. This work was supported by grants from Universidad de Buenos Aires (FA005) and CONICET (0082/92). | ||
| 593 | |a Laboratorio de Radioisótopos, Fac. de Farmacia/Bioquímiea, Universidad de Buenos Aires, Junin 956, 1113 Buenos Aires, Argentina | ||
| 593 | |a Departamento de Radiobiología, Comn. Nac. de Ener. Alómica, Laboratorio Tandar, Av. Gral Paz y Constituyentes, 1464 Pcia. de Buenos Aires, Argentina | ||
| 593 | |a Departamento de Biología, Fac. de Ciencias Exactas/Naturales, Ciudad Universitaria, Buenos Aires, Argentina | ||
| 690 | 1 | 0 | |a CAMP |
| 690 | 1 | 0 | |a HISTAMINE RECEPTORS |
| 690 | 1 | 0 | |a INOSITOL PHOSPHATES |
| 690 | 1 | 0 | |a MOUSE SKIN CARCINOGENESIS |
| 690 | 1 | 0 | |a 7,12 DIMETHYLBENZ[A]ANTHRACENE |
| 690 | 1 | 0 | |a ACETONE |
| 690 | 1 | 0 | |a CYCLIC AMP |
| 690 | 1 | 0 | |a HISTAMINE |
| 690 | 1 | 0 | |a HISTAMINE AGONIST |
| 690 | 1 | 0 | |a HISTAMINE H1 RECEPTOR |
| 690 | 1 | 0 | |a HISTAMINE H2 RECEPTOR |
| 690 | 1 | 0 | |a HISTAMINE RECEPTOR |
| 690 | 1 | 0 | |a INOSITOL PHOSPHATE |
| 690 | 1 | 0 | |a PHORBOL 13 ACETATE 12 MYRISTATE |
| 690 | 1 | 0 | |a PHOSPHATIDYLINOSITOL |
| 690 | 1 | 0 | |a CIMETIDINE |
| 690 | 1 | 0 | |a CYCLIC AMP |
| 690 | 1 | 0 | |a DRUG DERIVATIVE |
| 690 | 1 | 0 | |a HISTAMINE H1 RECEPTOR |
| 690 | 1 | 0 | |a HISTAMINE H1 RECEPTOR ANTAGONIST |
| 690 | 1 | 0 | |a HISTAMINE H2 RECEPTOR |
| 690 | 1 | 0 | |a HISTAMINE H2 RECEPTOR ANTAGONIST |
| 690 | 1 | 0 | |a MEPYRAMINE |
| 690 | 1 | 0 | |a PHOSPHATIDYLINOSITOL |
| 690 | 1 | 0 | |a TIOTIDINE |
| 690 | 1 | 0 | |a ANIMAL CELL |
| 690 | 1 | 0 | |a ANIMAL EXPERIMENT |
| 690 | 1 | 0 | |a ANIMAL MODEL |
| 690 | 1 | 0 | |a ARTICLE |
| 690 | 1 | 0 | |a CELLULAR DISTRIBUTION |
| 690 | 1 | 0 | |a CONTROLLED STUDY |
| 690 | 1 | 0 | |a DRUG HYDROLYSIS |
| 690 | 1 | 0 | |a FEMALE |
| 690 | 1 | 0 | |a MAST CELL |
| 690 | 1 | 0 | |a MOUSE |
| 690 | 1 | 0 | |a NONHUMAN |
| 690 | 1 | 0 | |a PHENOTYPE |
| 690 | 1 | 0 | |a SECOND MESSENGER |
| 690 | 1 | 0 | |a SIGNAL TRANSDUCTION |
| 690 | 1 | 0 | |a SKIN CARCINOGENESIS |
| 690 | 1 | 0 | |a TUMOR GROWTH |
| 690 | 1 | 0 | |a ANIMAL |
| 690 | 1 | 0 | |a CELL COUNT |
| 690 | 1 | 0 | |a CHEMICALLY INDUCED DISORDER |
| 690 | 1 | 0 | |a HYDROLYSIS |
| 690 | 1 | 0 | |a METABOLISM |
| 690 | 1 | 0 | |a PATHOLOGY |
| 690 | 1 | 0 | |a PATHOPHYSIOLOGY |
| 690 | 1 | 0 | |a PHYSIOLOGY |
| 690 | 1 | 0 | |a SKIN TUMOR |
| 690 | 1 | 0 | |a 9,10-DIMETHYL-1,2-BENZANTHRACENE |
| 690 | 1 | 0 | |a ANIMALS |
| 690 | 1 | 0 | |a CELL COUNT |
| 690 | 1 | 0 | |a CIMETIDINE |
| 690 | 1 | 0 | |a CYCLIC AMP |
| 690 | 1 | 0 | |a FEMALE |
| 690 | 1 | 0 | |a HISTAMINE H1 ANTAGONISTS |
| 690 | 1 | 0 | |a HISTAMINE H2 ANTAGONISTS |
| 690 | 1 | 0 | |a HYDROLYSIS |
| 690 | 1 | 0 | |a MAST CELLS |
| 690 | 1 | 0 | |a MICE |
| 690 | 1 | 0 | |a PHOSPHATIDYLINOSITOLS |
| 690 | 1 | 0 | |a PYRILAMINE |
| 690 | 1 | 0 | |a RECEPTORS, HISTAMINE H1 |
| 690 | 1 | 0 | |a RECEPTORS, HISTAMINE H2 |
| 690 | 1 | 0 | |a SECOND MESSENGER SYSTEMS |
| 690 | 1 | 0 | |a SIGNAL TRANSDUCTION |
| 690 | 1 | 0 | |a SKIN NEOPLASMS |
| 690 | 1 | 0 | |a TETRADECANOYLPHORBOL ACETATE |
| 700 | 1 | |a Molinari, B. | |
| 700 | 1 | |a Duran, H. | |
| 700 | 1 | |a Palmieri, M. | |
| 700 | 1 | |a Davio, C. | |
| 700 | 1 | |a Cricco, G. | |
| 700 | 1 | |a Bergoc, R. | |
| 700 | 1 | |a Rivera, E. | |
| 773 | 0 | |d 1997 |g v. 46 |h pp. 292-298 |k n. 8 |p INFLAMM. RES. |x 10233830 |t Inflammation Research | |
| 856 | 4 | 1 | |u https://www.scopus.com/inward/record.uri?eid=2-s2.0-0030612654&doi=10.1007%2fs000110050190&partnerID=40&md5=b7d7f31fc78d583c4f32932d622b5701 |y Registro en Scopus |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s000110050190 |y DOI |
| 856 | 4 | 0 | |u https://hdl.handle.net/20.500.12110/paper_10233830_v46_n8_p292_Fitzsimons |y Handle |
| 856 | 4 | 0 | |u https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_10233830_v46_n8_p292_Fitzsimons |y Registro en la Biblioteca Digital |
| 961 | |a paper_10233830_v46_n8_p292_Fitzsimons |b paper |c PE | ||
| 962 | |a info:eu-repo/semantics/article |a info:ar-repo/semantics/artículo |b info:eu-repo/semantics/publishedVersion | ||
| 999 | |c 81125 | ||