Use of antiepileptic drugs in nontraumatic neurosurgical procedures: Is there any best route and time of administration?
We assessed in 15 consecutive patients the best route and time of administration for phenytoin (PHT) prophylaxis in neurosurgical procedures. We also correlated PHT levels in serum and cerebrospinal fluid after oral and parenteral loading doses. The mean PHT level was 13.9 μg/ml in serum and 2.03 μg...
Guardado en:
| Autor principal: | |
|---|---|
| Otros Autores: | , , , , , , |
| Formato: | Capítulo de libro |
| Lenguaje: | Inglés |
| Publicado: |
Lippincott Williams and Wilkins
1997
|
| Acceso en línea: | Registro en Scopus DOI Handle Registro en la Biblioteca Digital |
| Aporte de: | Registro referencial: Solicitar el recurso aquí |
| LEADER | 05815caa a22009137a 4500 | ||
|---|---|---|---|
| 001 | PAPER-20165 | ||
| 003 | AR-BaUEN | ||
| 005 | 20230518205133.0 | ||
| 008 | 190411s1997 xx ||||fo|||| 00| 0 eng|d | ||
| 024 | 7 | |2 scopus |a 2-s2.0-0030823679 | |
| 024 | 7 | |2 cas |a phenytoin, 57-41-0, 630-93-3 | |
| 040 | |a Scopus |b spa |c AR-BaUEN |d AR-BaUEN | ||
| 030 | |a CLNED | ||
| 100 | 1 | |a Rabinowicz, A.L. | |
| 245 | 1 | 0 | |a Use of antiepileptic drugs in nontraumatic neurosurgical procedures: Is there any best route and time of administration? |
| 260 | |b Lippincott Williams and Wilkins |c 1997 | ||
| 270 | 1 | 0 | |m Rabinowicz, A.L.; IINRC, Fleni, Montaneses 2325, 1428-Buenos Aires, Argentina |
| 506 | |2 openaire |e Política editorial | ||
| 504 | |a Hauser, W.A., Hesdorferr, D.C., (1990) Epilepsy: Frequency, Causes and Consequences, pp. 1-51. , New York: Demos | ||
| 504 | |a Annegers, J.F., Grabow, J.D., Groover, R.V., Laws, E., Elveback, L., Kurland, L., Seizures after head trauma: A population study (1980) Neurology, 30, pp. 683-689 | ||
| 504 | |a Foly, P.M., Copeland, G.P., Shaw, M.D., The incidence of postoperative seizures (1981) Acta Neurochir, 55, pp. 253-256 | ||
| 504 | |a Sabo, R.A., Hanigan, W.C., Aldag, J.C., Chronic subdural hematomas and seizures: The role of prophylactic anticonvulsive medication (1995) Surg Neurol, 43, pp. 579-582 | ||
| 504 | |a Temkin, N.K., Dikmen, S.S., Wilensky, A.J., A randomized, double blind study of phenytoin for the prevention of posttraumatic seizures (1990) N Engl J Med, 323, pp. 497-502 | ||
| 504 | |a DeGiorgio, C., Rabinowicz, A.L., Seizures (1992) Brain Surgery: Complication Avoidance and Management, 1, pp. 155-162. , Apuzzo M, ed., New York: Churchill Livingstone | ||
| 504 | |a Treatment of convulsive status epilepticus (1993) JAMA, 270, pp. 854-859 | ||
| 504 | |a Rabinowicz, A.L., Ginsburg, D., DeGiorgio, C.M., Gott, P., Giannota, S., Unruptured intracranial aneurysms: Seizures and antiepileptic drug treatment following surgery (1991) J Neurosurg, 75, pp. 371-373 | ||
| 504 | |a Wang, E.C., Geyer, J.R., Berger, M.S., Incidence of postoperative epilepsy in children following subfrontal craniotomy for tumor (1994) Pediatr Neurosurg, 21, pp. 165-172 | ||
| 504 | |a Young, B., Rapp, R.P., Norton, J.A., Failure of prophylactically administered phenytoin to prevent early posttraumatic seizures (1983) J Neurosurg, 58, pp. 231-236 | ||
| 504 | |a Woodbury, D., (1989) Phenytoin: Absortion, Distribution and Excretion, pp. 177-195. , Levy R, Dreifuss F, Mattson R, Meldrum B, Penry K, eds. New York: Raven Press | ||
| 504 | |a Lolin, Y., Ratnaraj, N., Hjelm, M., Patsalos, P., Antiepileptic drug pharmacokinetics and neuropharmacokinetics in individual rats by repetitive withdrawl of blood and cerebrospinal fluid: Phenytoin (1994) Epilepsy Res, 19, pp. 99-110 | ||
| 504 | |a Woodbury, D.M., Phenytoin: Proposed mechanisms of anticonvulsant action (1980) Adv Neurol, 27, pp. 447-471 | ||
| 520 | 3 | |a We assessed in 15 consecutive patients the best route and time of administration for phenytoin (PHT) prophylaxis in neurosurgical procedures. We also correlated PHT levels in serum and cerebrospinal fluid after oral and parenteral loading doses. The mean PHT level was 13.9 μg/ml in serum and 2.03 μg/ml in cerebrospinal fluid (CSF), with a significant correlation between levels in both compartments (r = 0.73, p <0.01). Mean PHT levels among the different groups were not statistically significant. We conclude that therapeutic levels of PHT in CSF can be achieved independently of the route of administration, as long as accepted loading doses are used. |l eng | |
| 593 | |a Departments of Neurology, Inst. de Invest. Neurologicas R., Buenos Aires, Argentina | ||
| 593 | |a Inst. de Invest. Neurologicas R., Montaneses 2325, 1428 - Buenos Aires, Argentina | ||
| 690 | 1 | 0 | |a ANTIEPILEPTIC DRUGS |
| 690 | 1 | 0 | |a NEUROSURGERY |
| 690 | 1 | 0 | |a PHENYTOIN |
| 690 | 1 | 0 | |a PROPHYLAXIS |
| 690 | 1 | 0 | |a ANTICONVULSIVE AGENT |
| 690 | 1 | 0 | |a PHENYTOIN |
| 690 | 1 | 0 | |a ADULT |
| 690 | 1 | 0 | |a AGED |
| 690 | 1 | 0 | |a ARTICLE |
| 690 | 1 | 0 | |a BRAIN ARTERIOVENOUS MALFORMATION |
| 690 | 1 | 0 | |a BRAIN ARTERY ANEURYSM |
| 690 | 1 | 0 | |a BRAIN TUMOR |
| 690 | 1 | 0 | |a CLINICAL ARTICLE |
| 690 | 1 | 0 | |a CLINICAL TRIAL |
| 690 | 1 | 0 | |a CONTROLLED CLINICAL TRIAL |
| 690 | 1 | 0 | |a CONTROLLED STUDY |
| 690 | 1 | 0 | |a DOSE RESPONSE |
| 690 | 1 | 0 | |a DRUG BLOOD LEVEL |
| 690 | 1 | 0 | |a DRUG CEREBROSPINAL FLUID LEVEL |
| 690 | 1 | 0 | |a EPILEPSY |
| 690 | 1 | 0 | |a FEMALE |
| 690 | 1 | 0 | |a HEAD INJURY |
| 690 | 1 | 0 | |a HUMAN |
| 690 | 1 | 0 | |a INTRAVENOUS DRUG ADMINISTRATION |
| 690 | 1 | 0 | |a MALE |
| 690 | 1 | 0 | |a MIDDLE CEREBRAL ARTERY |
| 690 | 1 | 0 | |a NEUROSURGERY |
| 690 | 1 | 0 | |a ORAL DRUG ADMINISTRATION |
| 690 | 1 | 0 | |a PRIORITY JOURNAL |
| 690 | 1 | 0 | |a RANDOMIZED CONTROLLED TRIAL |
| 700 | 1 | |a Salvat, J.M. | |
| 700 | 1 | |a Leiguarda, R.C. | |
| 700 | 1 | |a Demonty, F. | |
| 700 | 1 | |a Salvat, F. | |
| 700 | 1 | |a Cervio, A. | |
| 700 | 1 | |a Manes, F. | |
| 700 | 1 | |a Lazarowski, A. | |
| 773 | 0 | |d Lippincott Williams and Wilkins, 1997 |g v. 20 |h pp. 438-441 |k n. 5 |p CLIN. NEUROPHARMACOL. |x 03625664 |t Clinical Neuropharmacology | |
| 856 | 4 | 1 | |u https://www.scopus.com/inward/record.uri?eid=2-s2.0-0030823679&doi=10.1097%2f00002826-199710000-00008&partnerID=40&md5=f4046079dbe49718f35b41b9315a68b2 |y Registro en Scopus |
| 856 | 4 | 0 | |u https://doi.org/10.1097/00002826-199710000-00008 |y DOI |
| 856 | 4 | 0 | |u https://hdl.handle.net/20.500.12110/paper_03625664_v20_n5_p438_Rabinowicz |y Handle |
| 856 | 4 | 0 | |u https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03625664_v20_n5_p438_Rabinowicz |y Registro en la Biblioteca Digital |
| 961 | |a paper_03625664_v20_n5_p438_Rabinowicz |b paper |c PE | ||
| 962 | |a info:eu-repo/semantics/article |a info:ar-repo/semantics/artículo |b info:eu-repo/semantics/publishedVersion | ||
| 999 | |c 81118 | ||