Anosognosia and procedural learning in Alzheimer's disease

Awareness of cognitive deficits may rely on the implicit learning of intellectual limitations, and anosognosia in Alzheimer's disease (AD) may result from deficits in implicit learning. To examine this hypothesis, a consecutive series of 55 patients with probable AD were divided into groups wit...

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Autor principal: Starkstein, S.E
Otros Autores: Sabe, L., Cuerva, A.G, Kuzis, G., Leiguarda, R.
Formato: Capítulo de libro
Lenguaje:Inglés
Publicado: 1997
Acceso en línea:Registro en Scopus
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100 1 |a Starkstein, S.E. 
245 1 0 |a Anosognosia and procedural learning in Alzheimer's disease 
260 |c 1997 
270 1 0 |m Starkstein, S.E.; Inst Invest Neurologicas Raul Carrea, Montanieses 2325, 1428 Buenos Aires, Argentina 
506 |2 openaire  |e Política editorial 
504 |a Migliorelli, R., Teson, A., Sabe, L., Petracca, G., Petracchi, M., Leiguarda, R., Starkstein, S.E., Anosognosia in Alzheimer's disease: A study of associated factors (1995) J Neuropsychiat Clin Neurosci, 7, pp. 338-344 
504 |a Reisberg, B., Gordon, B., McCarthy, M., Insight and denial accompanying progressive cognitive decline in normal aging and Alzheimer's disease (1985) Geriatric Psychiatry: Ethical and Legal Issues, , Stanley B, ed. Washington, D.C.: American Psychiatric Press 
504 |a Feher, E.P., Mahurin, R.K., Inbody, S.B., Crook, T.H., Pirozzolo, F.J., Anosognosia in Alzheimer's disease (1991) Neuropsychiatr, Neuropsychol Behav Neurol, 4, pp. 136-146 
504 |a Sevush, S., Leve, N., Denial of memory deficit in Alzheimer's disease (1994) Am J Psychiatry, 150, pp. 748-751 
504 |a Lóper, O.L., Becker, J.T., Somsak, D., Dew, M.A., DeKosky, S.T., Awareness of cognitive deficits in probable Alzheimer's disease (1994) Eur Neurol, 34, pp. 277-282 
504 |a Michon, A., Deweer, B., Pillon, B., Agid, Y., Dubois, B., Relation of anosognosia to frontal lobe dysfunction in Alzheimer's disease (1994) J Neurol Neurosurg Psychiatry, 57, pp. 805-809 
504 |a Reed, B.R., Jagust, W.J., Coulter, L., Anosognosia in Alzheimer's disease: Relationships to depression, cognitive function, and cerebral perfusion (1993) J Clin Exp Neuropsychol, 15, pp. 231-244 
504 |a Starkstein, S.E., Migliorelli, R., Sabe, L., Teson, A., Vázquez, S., Leiguarda, R., ASPECT study of anosognosia in Alzheimer's disease (1995) Arch Neurol, 52, pp. 415-420 
504 |a Me Khann, G., Drachman, D., Folstein, M.F., Katzman, R., Price, D., Stadlan, E.M., Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA work group under the auspices of department of health and human services task force on Alzheimer's disease (1984) Neurology, 34, pp. 939-944 
504 |a Hachinski, V.C., Iliff, L.D., Zilhka, L., Cerebral blood flow in dementia (1975) Arch Neurol, 40, pp. 97-103 
504 |a Folstein, M.F., Folstein, S.E., McHugh, P.R., Mini-mental state: A practical method for grading the cognitive state of patients for the clinician (1975) J Psychiat Res, 12, pp. 189-198 
504 |a Buschke, H., Fuld, P.A., Evaluating storage, retention, and retrieval in disordered memory and learning (1974) Neurology, 24, pp. 1019-1025 
504 |a Sabe, L., Jason, L., Juejati, M., Leiguarda, R., Starkstein, S.E., Dissociation between declarative and procedural learning in dementia and depression (1995) J Clin Exp Neuropsychol, 17, pp. 841-848 
504 |a Benton, A.L., (1974) The Revised Visual Retention Test, 4th Ed., , New York: The Psychological Corporation 
504 |a Kertesz, A., (1982) Western Aphasia Battery, , New York: Grune and Stratton 
504 |a Wechsler, D., (1955) Wechsler Adult Intelligence Scale Manual, , New York: The Psychological Corporation 
504 |a Nelson, H.E., A modified card sorting test sensitive to frontal lobe defects (1976) Cortex, 12, pp. 313-324 
504 |a Reitan, R.M., Validity of the trail making test as an indicator of organic brain damage (1958) Perc Mot Skills, 8, pp. 271-276 
504 |a Benton, A.L., Differential behavioral effects in frontal lobe disease (1968) Neuropsychologia, 6, pp. 53-60 
504 |a Kaplan, E.F., Goodglass, H., Weintraub, S., (1993) The Boston Naming Test, , Philadelphia: Lea & Febiger 
504 |a De Renzi, E., Faglioni, P., Development of a shortened version of the token test (1978) Cortex, 14, pp. 41-49 
504 |a Raven, J.C., Court, J.H., Raven, J., (1986) Manual for Raven's Progressive Matrices and Vocabulary Scales, , London: H. K. Lewis & Co, Ltd 
504 |a Mishkin, M., Malamut, B., Bachevalier, J., Memories and habits: Two neural systems (1984) The Neurobiology of Learning and Memory, , Lynch G, McGaugh JL, Weinberger NM, eds. New York: Guilford Press 
504 |a Grosse, D.A., Wilson, R.S., Maze learning in Alzheimer's disease (1991) Brain and Cognition, 15, pp. 1-9 
520 3 |a Awareness of cognitive deficits may rely on the implicit learning of intellectual limitations, and anosognosia in Alzheimer's disease (AD) may result from deficits in implicit learning. To examine this hypothesis, a consecutive series of 55 patients with probable AD were divided into groups with mild (n = 13), severe (n = 12), or no anosognosia (n = 30) and were assessed with a neuropsychological battery that included tests of declarative and procedural learning. Whereas there were no significant between-group differences in tests of declarative learning (the Buschke Selective Reminding Test and the Benton Visual Retention Test), patients with severe anosognosia showed a significantly worse performance on procedural learning (as measured with the Maze Learning Test) and a test assessing set shifting abilities (the Wisconsin Card Sorting Test) than AD patients without anosognosia. The authors' results suggest that deficits in procedural learning and anosognosia in AD may result from dysfunction in habit-learning systems.  |l eng 
593 |a Department of Behavioral Neurology, Raúl Carrea Institute of Neurological Research, Buenos Aires, Argentina 
593 |a Department of Clinical Neurology, Raúl Carrea Institute of Neurological Research, Buenos Aires, Argentina 
593 |a Instituto de Investigaciones Neurológicas Raúl Carrea, Montañeses 2325, 1428 Buenos Aires, Argentina 
690 1 0 |a ALZHEIMER'S DISEASE 
690 1 0 |a ANOSOGNOSIA 
690 1 0 |a LEARNING 
690 1 0 |a MEMORY 
690 1 0 |a ADULT 
690 1 0 |a AGED 
690 1 0 |a ALZHEIMER DISEASE 
690 1 0 |a ANOSOGNOSIA 
690 1 0 |a ARTICLE 
690 1 0 |a AWARENESS 
690 1 0 |a COGNITIVE DEFECT 
690 1 0 |a CONTROLLED STUDY 
690 1 0 |a DISEASE SEVERITY 
690 1 0 |a HABIT 
690 1 0 |a HUMAN 
690 1 0 |a LEARNING 
690 1 0 |a MAJOR CLINICAL STUDY 
690 1 0 |a MAZE TEST 
690 1 0 |a NEUROPSYCHOLOGICAL TEST 
690 1 0 |a PERFORMANCE 
690 1 0 |a PRIORITY JOURNAL 
690 1 0 |a AGED 
690 1 0 |a AGED, 80 AND OVER 
690 1 0 |a AGNOSIA 
690 1 0 |a ALZHEIMER DISEASE 
690 1 0 |a ATTENTION 
690 1 0 |a AWARENESS 
690 1 0 |a DISCRIMINATION LEARNING 
690 1 0 |a FEMALE 
690 1 0 |a FRONTAL LOBE 
690 1 0 |a HUMANS 
690 1 0 |a MALE 
690 1 0 |a MAZE LEARNING 
690 1 0 |a MENTAL RECALL 
690 1 0 |a MIDDLE AGED 
690 1 0 |a NEUROPSYCHOLOGICAL TESTS 
690 1 0 |a PROBLEM SOLVING 
690 1 0 |a RETENTION (PSYCHOLOGY) 
700 1 |a Sabe, L. 
700 1 |a Cuerva, A.G. 
700 1 |a Kuzis, G. 
700 1 |a Leiguarda, R. 
773 0 |d 1997  |g v. 10  |h pp. 96-101  |k n. 2  |p NEUROPSYCHIATRY NEUROPSYCHOL. BEHAV. NEUROL.  |x 0894878X  |t Neuropsychiatry, Neuropsychology and Behavioral Neurology 
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