Temperature acclimation of Trypanosoma cruzi epimastigote and metacyclic trypomastigote lipids
This study examines the changes in cellular lipids that take place when Trypanosoma cruzi epimastigotes and metacyclic trypomastigotes are transferred from 28 to 37°C. We found a rise in the sterol to phospholipid ratio, as well as in the triacylglycerol and steryl ester cellular content in T. cruzi...
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| Otros Autores: | , , , , , |
| Formato: | Capítulo de libro |
| Lenguaje: | Inglés |
| Publicado: |
1997
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| Acceso en línea: | Registro en Scopus DOI Handle Registro en la Biblioteca Digital |
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| LEADER | 09979caa a22011657a 4500 | ||
|---|---|---|---|
| 001 | PAPER-20042 | ||
| 003 | AR-BaUEN | ||
| 005 | 20230518205126.0 | ||
| 008 | 190411s1997 xx ||||fo|||| 00| 0 eng|d | ||
| 024 | 7 | |2 scopus |a 2-s2.0-0030737750 | |
| 024 | 7 | |2 cas |a Fatty Acid Desaturases, EC 1.14.99.-; Fatty Acids; Lipids; Phospholipids; Sterols; Triglycerides | |
| 040 | |a Scopus |b spa |c AR-BaUEN |d AR-BaUEN | ||
| 030 | |a MBIPD | ||
| 100 | 1 | |a Florin-Christensen, M. | |
| 245 | 1 | 0 | |a Temperature acclimation of Trypanosoma cruzi epimastigote and metacyclic trypomastigote lipids |
| 260 | |c 1997 | ||
| 270 | 1 | 0 | |m Florin-Christensen, M.; INEUCI-CONICET, Casilla de Correo 137, (RA-1663) San Miguel, Argentina; email: florin@biolo.bg.fcen.uba.ar |
| 506 | |2 openaire |e Política editorial | ||
| 504 | |a Al-Bashir, N.T., Rassam, M.B., Axenic cultivation of amastigotes of Leishmania donovani and Leishmania major and their infectivity (1992) Ann Trop Med Parasitol, 86, pp. 487-502 | ||
| 504 | |a Bates, P.A., Complete developmental cycle of Leishmania mexicana in axenic culture (1994) Parasitology, 108, pp. 1-10 | ||
| 504 | |a De-Rossell, R.A., Rossell, O., De Jesus De Duran, R., Rodriguez, A.M., Thermotherapy v. antimonials: What happens after the healing of cutaneous leishmaniasis lesions? (1993) Ann Trop Med Parasitol, 87, pp. 23-30 | ||
| 504 | |a Navin, R.R., Arana, B.A., Arana, F.E., Maria De Merida, A., Castillo, A.L., Pozuelos, J.L., Placebo-controlled clinical trial of meglumine antimonate (glucantime) vs. localized controlled heat in the treatment of cutaneous leishmaniasis in Guatemala (1990) Am J Trop Med Hyg, 42, pp. 43-50 | ||
| 504 | |a MacFarlane, J., Blaxter, M.L., Bishop, R.P., Miles, M.A., Kelly, J.M., Identification and characterization of a Leishmania donovani antigen belonging to the 70 kDa heat-shock protein family (1990) Eur J Biochem, 190, pp. 377-384 | ||
| 504 | |a Rondinelli, E., Conservation of heat-shock proteins in Trypanosoma cruzi (1994) Parasitol Today, 10, pp. 172-176 | ||
| 504 | |a Sinensky, M., Homeoviscous adaptation - A homeostatic process that regulates the viscosity of membrane lipids in Escherichia coli (1974) Proc Natl Acad Sci USA, 71, pp. 522-525 | ||
| 504 | |a Roy, R., Das, A.B., Farkas, T., Role of environmental thermal fluctuation in seasonal variation of fatty acid composition of total lipid in fatbody of the cockroach Periplaneta americana (1991) J Therm Biol, 16, pp. 211-215 | ||
| 504 | |a Imhoff, J.F., Thiemann, B., Influence of salt concentration and temperature on the fatty acid compositions of Ectothiorhodospira and other halophilic phototrophic purple bacteria (1991) Arch Microbiol, 156, pp. 370-375 | ||
| 504 | |a Buzzi, M., Felipe, M.S.S., De Oliveira-Azevedo, M., De Araujo-Caldas, R., Membrane lipid composition and invertase secretion of Neurospora crassa and its wall-less mutant slime: Effects of temperature and the surfactant Tween 80 (1993) J Gen Microbiol, 139, pp. 1885-1889 | ||
| 504 | |a Vigh, L., Los, D.A., Horvath, I., Murata, N., The primary signal in the biological perception of temperature: Pd-catalyzed hydrogenation of membrane lipids stimulated the expression of the desA gene in Synechocystis PCC 6803 (1993) Proc Natl Acad Sci USA, 90, pp. 9090-9094 | ||
| 504 | |a Jones, A.L., Hann, A.C., Harwood, J.L., Lloyd, D., Temperature-induced membrane-lipid adaptation in Acanthamoeba castellanii (1993) Biochem J, 290, pp. 273-278 | ||
| 504 | |a Ramesha, C.S., Thompson, G.A., Cold stress induces in situ phospholipid molecular species changes in cell surface membranes (1983) Biochim Biophys Acta, 731, pp. 251-260 | ||
| 504 | |a Kameyama, Y., Yoshioka, S., Nozawa, Y., Mechanism for adaptive modification during cold acclimation of phospholipid acyl chain composition in Tetrahymena. 1. Principal involvement of deacylation-reacylation (1984) Biochim Biophys Acta, 793, pp. 28-33 | ||
| 504 | |a Thompson, G.A., Lipid molecular species retailoring and membrane fluidity (1987) Trans Biochem Soc, 17, pp. 286-289 | ||
| 504 | |a Bligh, E.G., Dyer, W.J., A rapid method of total lipid extraction and purification (1959) Can J Biochem Physiol, 37, pp. 911-917 | ||
| 504 | |a Isola, E.L.D., Lammel, E.M., Gonzalez Cappa, S.M., Trypanosoma cruzi: Differentiation after interaction of epimastigotes and Triatoma infestans intestinal homogenates (1986) Exp Parasitol, 62, pp. 329-335 | ||
| 504 | |a Kates, M., Techniques of lipidology (1986) Laboratory Techniques in Biochemistry and Molecular Biology, 3 (2 PART). , Burdon RH, Knippenberg PH, editors. Eisevier, Amsterdam | ||
| 504 | |a Bronia, D.H., Aguerri, A.M., Bertetto, S.T., Trypanosoma cruzi: Changes in lipid composition during aging in culture (1986) Exp Parasitol, 61, pp. 151-159 | ||
| 504 | |a Kaneda, Y., Nagakura, K., Goutsu, T., Lipid composition of three morphological stages of Trypanosoma cruzi (1986) Comp Biochem Physiol, 83 B, pp. 533-536 | ||
| 504 | |a Esteves, M.G., Gonzalez-Perdomo, M., Alviano, C.S., Angluster, J., Goldenberg, S., Changes in fatty acid composition associated with differentiation of Trypanosoma cruzi (1989) FEMS Microbiol Lett, 59, pp. 31-34 | ||
| 504 | |a De Lema, M.G., Aeberhard, E., Desaturation of fatty acids in Trypanosoma cruzi (1986) Lipids, 21, pp. 718-720 | ||
| 504 | |a Aeberhard, E., De Lema, M.G., Bronia, I.H., Biosynthesis of fatty acids by Trypanosoma cruzi (1981) Lipids, 16, pp. 623-625 | ||
| 520 | 3 | |a This study examines the changes in cellular lipids that take place when Trypanosoma cruzi epimastigotes and metacyclic trypomastigotes are transferred from 28 to 37°C. We found a rise in the sterol to phospholipid ratio, as well as in the triacylglycerol and steryl ester cellular content in T. cruzi epimastigotes. In addition, saturated to unsaturated fatty acid ratios in phospholipids increase. This latter effect appears to be due to two concurrent processes. Firstly, fatty acyl Δ9 and, especially, Δ12 desaturations are significantly diminished at 37°C. Secondly, triacylglycerols and steryl esters undergo changes in their fatty acyl composition opposite to those simultaneously observed in phospholipids, i.e. the ratio of saturated to unsaturated fatty acids markedly decreases. Similar alterations in each of the lipid classes and in the fatty acid composition of polar and neutral lipids were found in cultured metacyclic trypomastigotes on exposure to the same shift-up. These observations suggest that a global remodeling of cellular lipids that involves extensive fatty acid exchange between neutral and polar lipid pools represents a novel and important mechanism of adaptation of the parasites to the temperature changes they encounter in their life cycle. |l eng | |
| 536 | |a Detalles de la financiación: TWAS | ||
| 536 | |a Detalles de la financiación: Third World Academy of Sciences | ||
| 536 | |a Detalles de la financiación: National Council for Scientific Research | ||
| 536 | |a Detalles de la financiación: Stavros Niarchos Foundation | ||
| 536 | |a Detalles de la financiación: Consejo Nacional de Investigaciones Científicas y Técnicas | ||
| 536 | |a Detalles de la financiación: Support from the National Research Council of Argentina (CONICET), the Third World Academy of Sciences (TWAS) and the Danish Research Councils of Natural Sciences and Medical Sciences (SNF and SLF) is gratefully acknowledged. | ||
| 593 | |a Institute of Neuroscience (INEUCI), CONICET-UBA, Ciudad Universitaria, 4o Piso, RA-1428 Buenos Aires, Argentina | ||
| 593 | |a Institute of Biochemistry (INIBIOLP), CONICET-UNLP, Avenida 60 y 120, RA-1900 La Plata, Argentina | ||
| 593 | |a Department of Microbiology, Univ. of Buenos Aires Medical School, Paraguay 1256, RA-1113 Buenos Aires, Argentina | ||
| 593 | |a Dept. of Anatomy and Cell Biology, Odense University, Campusvej 55, DK-5230 Odense M, Denmark | ||
| 593 | |a INEUCI-CONICET, Casilla de Correo 137, (RA-1663) San Miguel, Argentina | ||
| 690 | 1 | 0 | |a FATTY ACIDS |
| 690 | 1 | 0 | |a LIPIDS |
| 690 | 1 | 0 | |a PHOSPHOLIPIDS |
| 690 | 1 | 0 | |a STEROLS |
| 690 | 1 | 0 | |a TEMPERATURE |
| 690 | 1 | 0 | |a TRYPANOSOMA CRUZI |
| 690 | 1 | 0 | |a FATTY ACID |
| 690 | 1 | 0 | |a LIPID |
| 690 | 1 | 0 | |a STEROL |
| 690 | 1 | 0 | |a ARTICLE |
| 690 | 1 | 0 | |a EPIMASTIGOTE |
| 690 | 1 | 0 | |a FATTY ACID DESATURATION |
| 690 | 1 | 0 | |a LIFE CYCLE |
| 690 | 1 | 0 | |a LIPID COMPOSITION |
| 690 | 1 | 0 | |a LIPID METABOLISM |
| 690 | 1 | 0 | |a PRIORITY JOURNAL |
| 690 | 1 | 0 | |a TEMPERATURE ACCLIMATIZATION |
| 690 | 1 | 0 | |a TRYPANOSOMA CRUZI |
| 690 | 1 | 0 | |a TRYPOMASTIGOTE |
| 690 | 1 | 0 | |a ADAPTATION, PHYSIOLOGICAL |
| 690 | 1 | 0 | |a ANIMALS |
| 690 | 1 | 0 | |a FATTY ACID DESATURASES |
| 690 | 1 | 0 | |a FATTY ACIDS |
| 690 | 1 | 0 | |a LIPID METABOLISM |
| 690 | 1 | 0 | |a LIPIDS |
| 690 | 1 | 0 | |a PHOSPHOLIPIDS |
| 690 | 1 | 0 | |a STEROLS |
| 690 | 1 | 0 | |a TEMPERATURE |
| 690 | 1 | 0 | |a TRIGLYCERIDES |
| 690 | 1 | 0 | |a TRYPANOSOMA CRUZI |
| 690 | 1 | 0 | |a TRYPANOSOMA |
| 690 | 1 | 0 | |a TRYPANOSOMA CRUZI |
| 700 | 1 | |a Florin-Christensen, J. | |
| 700 | 1 | |a De Isola, E.D. | |
| 700 | 1 | |a Lammel, E. | |
| 700 | 1 | |a Meinardi, E. | |
| 700 | 1 | |a Brenner, R.R. | |
| 700 | 1 | |a Rasmussen, L. | |
| 773 | 0 | |d 1997 |g v. 88 |h pp. 25-33 |k n. 1-2 |p MOL. BIOCHEM. PARASITOL. |x 01666851 |w (AR-BaUEN)CENRE-6136 |t Molecular and Biochemical Parasitology | |
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| 856 | 4 | 0 | |u https://doi.org/10.1016/S0166-6851(97)00056-X |y DOI |
| 856 | 4 | 0 | |u https://hdl.handle.net/20.500.12110/paper_01666851_v88_n1-2_p25_FlorinChristensen |y Handle |
| 856 | 4 | 0 | |u https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_01666851_v88_n1-2_p25_FlorinChristensen |y Registro en la Biblioteca Digital |
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| 963 | |a VARI | ||
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