Disseminated tuberculosis with cutaneous manifestations in AIDS patients. Presentation of 4 cases

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BACKGROUND: Acute cutaneous miliary tuberculosis is a rare form of Mycobacterium tuberculosis infection which has been described in only 25 published cases in the last 15 years. The appearance of serious disseminated forms of tuberculosis is enhanced by the severe immunodeficiency which characterize...

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Autor principal: Esquivel, S.P
Otros Autores: Vigna, L., Velázquez, J., Cangelosi, D., Figueiras, O., Solari, R., Corti, M., Massini, R.
Formato: Capítulo de libro
Lenguaje:Español
Publicado: 1998
Acceso en línea:Registro en Scopus
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Registro en la Biblioteca Digital
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Biblioteca Central Dr. Luis F. Leloir (FCEN) de Universidad de Buenos Aires
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100 1 |a Esquivel, S.P. 
245 1 0 |a Disseminated tuberculosis with cutaneous manifestations in AIDS patients. Presentation of 4 cases 
246 3 1 |a Tuberculosis diseminada con manifestaciones cutaneas en pacientes con sida. A proposito de 4 observaciones 
260 |c 1998 
270 1 0 |m Corti, M.; Unidad 10, Pabellon 22, Hospital F.J. Muniz, Uspallata 272 (CP 1152), Buenos Aires, Argentina 
506 |2 openaire  |e Política editorial 
504 |a Mellado, B., Pedrol, E., Casademont, J., Absceso subcutáneo tuberculoso como forma de presentación de un síndrome de inmunodeficiencia adquirida (1993) Rev Clin Esp, 192, pp. 95-96 
504 |a Styblo, K., The global aspects of tuberculosis and HIV infection (1990) Bull Int Union Tuberc Lung Dis, 65, pp. 28-32 
504 |a Ballestrino, E., Estado actual de la tuberculosis en la Repüblica Argentina (1995) XXV Congreso Argentino de Tisiología y Neumología, , Octubre 
504 |a Fox, W., Considérations générales sur le choix et le maintenement des régimes therapeutiques dans la tuberculose pulmonaire (1972) Bull UICT, 47, p. 51 
504 |a Shafer, R.W., Edlin, B., Tuberculosis in patients with human immunodeficiency virus infection: Perspective on the past decade (1996) Clin Infect Dis, 22, pp. 683-704 
504 |a Shafer, R.W., Kim, D.S., Weiss, J.P., Extrapulmonary tuberculosis in patients with human immunodeficiency virus infection (1991) Medicine, 70, pp. 384-397. , Baltimore 
504 |a Neville, K., Bromberg, A., Bormberg, R., The third epidemic of multidrug resistant tuberculosis (1994) Chest, 105, pp. 45-48 
504 |a Bustillo, C.P., Lessnau, K.D., Sanjana, V., Multidrug resistant Mycobacterium tuberculosis in patients with human immunodeficiency virus infection (1992) Chest, 102, pp. 797-801 
504 |a Frieden, T.R., Sterling, T., Pablos-Méndez, A., The emergence of drug-resistant tuberculosis in New York City (1993) N Engl J Med, 328, pp. 521-526 
504 |a (1994) Tb Epidemic Outparing New Drug Development, , Press Release WHO/89 
504 |a Grosset, J.H., Treatment in tuberculosis in HIV infection (1992) Tuberc Lung Dis, 73, pp. 378-383 
504 |a McGregor, R.R., Cutaneous tuberculosis (1995) Clin Dermatol, 13, pp. 245-255 
504 |a Castro, K., Tuberculosis as an oportunistic disease in persons infected with HIV (1995) Clin Infect Dis, 21, pp. 68-71 
504 |a Chen, C.H., Shih, J.F., Wang, L.S., Tuberculous subcutaneous abscess: An analysis of seven cases (1996) Tuberc Lung Dis, 77, pp. 184-187 
504 |a Des Prez, R.M., Heim, C.R., Mycobacterium tuberculosis (1990) Principles and Practice of Infectious Diseases (3a. Ed), pp. 1.877-1.906. , Mandell G, Douglas R, Bennett J, editores. Nueva York: Churchill Livingstone 
504 |a Schermer, D.R., Simpson, C.G., Haserick, J.R., Tuberculosis cutis miliari acuta generalisata. Report of case in an adult and a review of the literature (1969) Arch Dermatol, 99, pp. 64-69 
504 |a Stack, R.J., Bickley, L.K., Coppel, I.G., Miliary tuberculosis presenting as skin lesions in a patient with acquired inmunodeficiency syndrome (1990) J Am Acad Dermatol, 23, pp. 1.031-1.035 
504 |a Rohatgi, P.K., Palazzolo, J.V., Saini, N.B., Acute miliary tuberculosis of the skin in acquired immunodeficiency syndrome (1992) J Am Acad Dermatol, 26, pp. 356-359 
504 |a Bassiri, A., Chan, N.B., McLeod, A., Disseminated cutaneous infection due to Mycobacterium tuberculosis in a person with AIDS (1993) Can Med Assoc J, 148, pp. 577-578 
504 |a Inwald, D., Nelson, M., Cramp, M., Cutaneous manifestations of mycobacterial infection in patients with AIDS (1994) Br J Dermatol, 130, pp. 111-114 
504 |a Gonzalez Montaner, L.J., Abbate, E.H., Dambrosio, A.O., Tuberculosis multirresistente: La amenaza en ciernes (1996) Rev Asoc Med Arg, 109, pp. 5-18 
520 3 |a BACKGROUND: Acute cutaneous miliary tuberculosis is a rare form of Mycobacterium tuberculosis infection which has been described in only 25 published cases in the last 15 years. The appearance of serious disseminated forms of tuberculosis is enhanced by the severe immunodeficiency which characterizes AIDS. METHODS: Four cases are described of disseminated tuberculosis with cutaneous localization clinically described as the acute miliary form. Patients had AIDS and CD4 lymphocyte levels of < 100 cells/mm3. Diagnosis was established in all cases by scraping of cutaneous lesions and direct examination with Ziehl-Neelsen coloration. RESULTS: The 4 patients presented signs and symptoms of disseminated tuberculosis with cutaneous manifestations, without a definite pattern and with localization predominantly on the thorax. Three had BAAR-positive sputum. Multiresistant strains of Mycobacterium tuberculosis were confirmed by antibiogram. One patient infected by a strain sensitive to first-line drugs responded favorably to conventional treatment for disseminated tuberculosis. In the remaining three with multiresistant strains, the evolution of the disease was rapid and unfavorable. CONCLUSIONS: Abrupt appearance of cutaneous lesions in a patient with disseminated tuberculosis and advanced HIV-disease should raise the suspicion of its etiology. Scraping and direct examination using Ziehl-Neelsen coloration is practical, economical and non-invasive diagnostic method.  |l eng 
593 |a Unidades 10/11, Pabellón 22, Hospital F.J. Muñiz, Buenos Aires, Argentina 
593 |a Unidad 10, Pabellón 22, Hospital F.J. Muñiz, Uspallata 2272 (CP 1152), Buenos Aires, Argentina 
690 1 0 |a CUTANEOUS TUBERCULOSIS 
690 1 0 |a HIV 
690 1 0 |a MYCOBACTERIUM TUBERCULOSIS 
690 1 0 |a TUBERCULOSTATIC AGENT 
690 1 0 |a ACQUIRED IMMUNE DEFICIENCY SYNDROME 
690 1 0 |a ADULT 
690 1 0 |a ANTIBIOTIC SENSITIVITY 
690 1 0 |a ARTICLE 
690 1 0 |a CASE REPORT 
690 1 0 |a FATALITY 
690 1 0 |a HUMAN 
690 1 0 |a MALE 
690 1 0 |a MILIARY TUBERCULOSIS 
690 1 0 |a MULTIDRUG RESISTANCE 
690 1 0 |a MYCOBACTERIUM TUBERCULOSIS 
690 1 0 |a ACQUIRED IMMUNE DEFICIENCY SYNDROME 
690 1 0 |a MILIARY TUBERCULOSIS 
690 1 0 |a SKIN TUBERCULOSIS 
690 1 0 |a ACQUIRED IMMUNODEFICIENCY SYNDROME 
690 1 0 |a ADULT 
690 1 0 |a HUMANS 
690 1 0 |a MALE 
690 1 0 |a TUBERCULOSIS, CUTANEOUS 
690 1 0 |a TUBERCULOSIS, MILIARY 
700 1 |a Vigna, L. 
700 1 |a Velázquez, J. 
700 1 |a Cangelosi, D. 
700 1 |a Figueiras, O. 
700 1 |a Solari, R. 
700 1 |a Corti, M. 
700 1 |a Massini, R. 
773 0 |d 1998  |g v. 16  |h pp. 31-34  |k n. 1  |p Enferm. Infecc. Microbiol. Clin.  |x 0213005X  |t Enfermedades Infecciosas y Microbiologia Clinica 
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856 4 0 |u https://hdl.handle.net/20.500.12110/paper_0213005X_v16_n1_p31_Esquivel  |y Handle 
856 4 0 |u https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0213005X_v16_n1_p31_Esquivel  |y Registro en la Biblioteca Digital 
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