Lymphocyte subsets and cytokines in adenoviral infection in children
To determine the distribution of major blood lymphocyte subsets we evaluated blood lymphocytes by flow cytometry in adenovirus-infected infants aged 30-730 d. In addition, interleukin-1-receptor antagonist, interleukin- 10 and transforming growth factor-β1 were measured in serum by enzyme- linked im...
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| Otros Autores: | , , , , |
| Formato: | Capítulo de libro |
| Lenguaje: | Inglés |
| Publicado: |
1998
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| Acceso en línea: | Registro en Scopus DOI Handle Registro en la Biblioteca Digital |
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| LEADER | 08655caa a22011537a 4500 | ||
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| 001 | PAPER-19781 | ||
| 003 | AR-BaUEN | ||
| 005 | 20230518205109.0 | ||
| 008 | 190411s1998 xx ||||fo|||| 00| 0 eng|d | ||
| 024 | 7 | |2 scopus |a 2-s2.0-0031658452 | |
| 024 | 7 | |2 cas |a Cytokines | |
| 040 | |a Scopus |b spa |c AR-BaUEN |d AR-BaUEN | ||
| 030 | |a APAEE | ||
| 100 | 1 | |a Mistchenko, A.S. | |
| 245 | 1 | 0 | |a Lymphocyte subsets and cytokines in adenoviral infection in children |
| 260 | |c 1998 | ||
| 270 | 1 | 0 | |m Mistchenko, A.S.; Laboratorio de Virologia, Hospital de Ninos 'R. Gutierrez', Gallo 1330 (1425) Buenos Aires, Argentina |
| 506 | |2 openaire |e Política editorial | ||
| 504 | |a Kajon, A.E., Wadell, G., Genome analysis of South American adenovirus strains of serotype 7 collected over a 7-year period (1994) J Clin Microbiol, 32, pp. 2321-2323 | ||
| 504 | |a Kajon, A.E., Mistchenko, A.S., Videla, C., Mortal, M., Wadell, G., Avendaño, L.F., Molecular epidemiology of adenovirus acute lower respiratory infections in children in the south cone of South America (1991-1994) (1996) J Med Virol, 48, pp. 151-156 | ||
| 504 | |a Murtagh, P., Cerqueiro, C., Halac, A., Avila, M., Kajon, A.E., Adenovirus type 7h respiratory infections: A report of 29 cases of acute lower respiratory disease (1993) Acta Paediatr, 82, pp. 557-561 | ||
| 504 | |a Mistchenko, A.S., Lenzi, H.L., Thompson, F.M., Mota, E.M., Vidaurreta, S., Navari, C., Participation of immune complexes in adenovirus infection (1992) Acta Paediatr, 81, pp. 983-988 | ||
| 504 | |a Bone, R.C., Toward a theory regarding the pathogenesis of the systemic inflammatory response syndrome: What we do and do not know about cytokine regulation (1996) Crit Care Med, 24, pp. 163-172 | ||
| 504 | |a Mistchenko, A.S., Diez, R.A., Mariani, A.L., Robaldo, J.F., Maffey, A.F., Bayley Bustamante, G., Cytokines in adenoviral disease in children: Interleukin 6, interleukin 8 and tumor necrosis factor α levels associate with different clinical outcomes (1994) J Pediatr, 124, pp. 714-720 | ||
| 504 | |a Anderson, M.R., Blumer, J.L., Advances in the therapy for sepsis in children (1997) Pediatr Clin N Am, 44, pp. 179-205 | ||
| 504 | |a Lejarraga, H., Orfila, G., Estandares de peso y estatura para niñas y niños argentinos desde el nacimiento hasta la madurez (1987) Arch Arg Pediatr, 85, pp. 209-222 | ||
| 504 | |a Laboratory technique for rapid diagnosis of viral infections: A memorandum (1977) Bull WHO, 55, pp. 33-37 | ||
| 504 | |a Thiele, G.M., Okano, M., Purtilo, D.T., Enzyme-linked immunosorbent assay (ELISA) for detecting antibodies in sera of patients with adenovirus infection (1989) J Virol Meth, 23, pp. 321-332 | ||
| 504 | |a Loken, M.R., Cell surface antigen and morphological characterization of leukocyte population by flow cytometry (1985) Methods in Hematology, pp. 132-144. , Beverly P. editor. London: Churchill Livingston | ||
| 504 | |a Erkeller-Yuksel, F.M., Deneys, V., Yuksel, B., Hannet, Y., Hulstaert, F., Hamilton, C., Age-related changes in human blood lymphocyte subpopulations (1992) J Pediatr, 120, pp. 216-222 | ||
| 504 | |a Comans-Bitter, W.M., De Groot, R., Van Der Beemd, R., Neijens, H.J., Hop, W.C.J., Groeneveld, K., Immunophenotyping of blood lymphocytes in childhood (1997) J Pediatr, 130, pp. 388-393 | ||
| 504 | |a Kimpen, J.L., Schaad, U.B., Treatment of respiratory syncytial virus bronchiolitis: 1995 poll of members of the European Society for Paediatric Infectious Diseases (1997) Pediatr Infect Dis J, 16, pp. 479-491 | ||
| 504 | |a Flomenberg, P., Piaskowski, V., Truitt, R.L., Casper, J.T., Characterization of human proliferative T cell responses to adenovirus (1995) J Infect Dis, 171, pp. 1090-1096 | ||
| 504 | |a Korner, H., Burgert, H.G., Down-regulation of HLA antigens by the adenovirus type 2 E3/19K protein in a T-lymphoma cell line (1994) J Virol, 68, pp. 1442-1448 | ||
| 504 | |a Stall, A.M., Wells, S.M., Lam, K.P., B-1 cells: Unique origins and functions (1996) Semin Immunol, 8, pp. 45-59 | ||
| 504 | |a Rosman, F.C., Mistchenko, A.S., Ladenheim, H.S., Nascimento, J.P., Outani, H.N., Madi, K., The acute and chronic human adenovirus pneumonia. The cellular and the extracellular matrix components (1996) Pediatr Pathol Lab Med, 16, pp. 521-541 | ||
| 504 | |a Simon, R.H., Engelhardt, J.F., Yang, Y., Zepeda, M., Weber-Pendleton, S., Grossman, M., Adenovirus-mediated transfer of the CFTR gene to lung of nonhuman primates: Toxicity study (1993) Human Gene Ther, 4, pp. 771-780 | ||
| 504 | |a Mc Cartney-Francis, N.L., Wahl, S.M., Transforming growth factor β: A matter of life and death (1994) J Leukocyte Biol, 55, pp. 401-409 | ||
| 520 | 3 | |a To determine the distribution of major blood lymphocyte subsets we evaluated blood lymphocytes by flow cytometry in adenovirus-infected infants aged 30-730 d. In addition, interleukin-1-receptor antagonist, interleukin- 10 and transforming growth factor-β1 were measured in serum by enzyme- linked immunosorbent assay. According to clinical parameters, mechanical ventilation and outcome, infections were classified as moderate (n = 15), severe (n = 11) and fatal (n = 12). Controls were 13 healthy children. In severe and fatal infection, T cells (CD5+/CD19-), NK effectors (CD16+), CD4+ T subset and B1 subset of B lymphocytes (CD5+/CD19+) were all significantly decreased. CD8+ cells were decreased in severe but not fatal cases. There was no difference in serum values of interleukin-10; however, fatal cases had high interleukin 1-receptor antagonist values. Interestingly, patients with moderate infection showed significantly increased values of transforming growth factor-β1. These results demonstrate that life- threatening adenoviral infection is associated with marked abnormalities in blood lymphocyte and cytokine profile. |l eng | |
| 593 | |a Laboratorio de Virología, Hosp. de Ninos R. Gutierrez, Argentina | ||
| 593 | |a Unidad de Terapia Intensiva, Hosp. de Ninos R. Gutierrez, Argentina | ||
| 593 | |a Departamento de Microbiología, Universidad de Buenos Aires, Argentina | ||
| 593 | |a Instituto de Cálculo, Facultad de Ciencias Exactas, Universidad de Buenos Aires, Argentina | ||
| 593 | |a Centro Respiratorio, Hosp. de Ninos R. Gutierrez, Argentina | ||
| 593 | |a Departamento de Farmacología, Facultad de Medicina, Universidad de Buenos Aires, Argentina | ||
| 593 | |a Laboratorio de Virología, Hosp. de Ninos R. Gutierrez, Gallo 1330, (1425) Buenos Aires, Argentina | ||
| 690 | 1 | 0 | |a ADENOVIRUS |
| 690 | 1 | 0 | |a CYTOKINES |
| 690 | 1 | 0 | |a LYMPHOCYTES |
| 690 | 1 | 0 | |a RESPIRATORY INFECTION |
| 690 | 1 | 0 | |a CD16 ANTIGEN |
| 690 | 1 | 0 | |a CD19 ANTIGEN |
| 690 | 1 | 0 | |a CD4 ANTIGEN |
| 690 | 1 | 0 | |a CD5 ANTIGEN |
| 690 | 1 | 0 | |a CD8 ANTIGEN |
| 690 | 1 | 0 | |a CYTOKINE |
| 690 | 1 | 0 | |a INTERLEUKIN 1 RECEPTOR BLOCKING AGENT |
| 690 | 1 | 0 | |a INTERLEUKIN 10 |
| 690 | 1 | 0 | |a TRANSFORMING GROWTH FACTOR BETA1 |
| 690 | 1 | 0 | |a ADENOVIRUS |
| 690 | 1 | 0 | |a ARTICLE |
| 690 | 1 | 0 | |a ARTIFICIAL VENTILATION |
| 690 | 1 | 0 | |a CLINICAL ARTICLE |
| 690 | 1 | 0 | |a CONTROLLED STUDY |
| 690 | 1 | 0 | |a FEMALE |
| 690 | 1 | 0 | |a HELPER CELL |
| 690 | 1 | 0 | |a HUMAN |
| 690 | 1 | 0 | |a INFANT |
| 690 | 1 | 0 | |a INFLAMMATION |
| 690 | 1 | 0 | |a MALE |
| 690 | 1 | 0 | |a NATURAL KILLER CELL |
| 690 | 1 | 0 | |a PRESCHOOL CHILD |
| 690 | 1 | 0 | |a PRIORITY JOURNAL |
| 690 | 1 | 0 | |a RESPIRATORY TRACT INFECTION |
| 690 | 1 | 0 | |a T LYMPHOCYTE |
| 690 | 1 | 0 | |a T LYMPHOCYTE SUBPOPULATION |
| 690 | 1 | 0 | |a VIRUS INFECTION |
| 690 | 1 | 0 | |a ADENOVIRIDAE INFECTIONS |
| 690 | 1 | 0 | |a CHILD, PRESCHOOL |
| 690 | 1 | 0 | |a CYTOKINES |
| 690 | 1 | 0 | |a FEMALE |
| 690 | 1 | 0 | |a HUMANS |
| 690 | 1 | 0 | |a INFANT |
| 690 | 1 | 0 | |a LYMPHOCYTE SUBSETS |
| 690 | 1 | 0 | |a MALE |
| 690 | 1 | 0 | |a PHENOTYPE |
| 700 | 1 | |a Koch, E.R.R. | |
| 700 | 1 | |a Kajon, A.E. | |
| 700 | 1 | |a Tibaldi, F. | |
| 700 | 1 | |a Maffey, A.F. | |
| 700 | 1 | |a Diez, R.A. | |
| 773 | 0 | |d 1998 |g v. 87 |h pp. 933-939 |k n. 9 |p Acta Paediatr. Int. J. Paediatr. |x 08035253 |t Acta Paediatrica, International Journal of Paediatrics | |
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| 856 | 4 | 0 | |u https://hdl.handle.net/20.500.12110/paper_08035253_v87_n9_p933_Mistchenko |y Handle |
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