An MRI study of the corpus callosum and cerebellum in mentally retarded autistic individuals

The areas of seven subregions of the corpus callosum and three subregions of the cerebellum were examined on midsagittal magnetic resonance imaging scans of 27 low-IQ autistic individuals and 17 nonautistic individuals of comparable mental age. Autistic individuals had a significantly smaller corpus...

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Autor principal: Manes, F.
Otros Autores: Piven, J., Vrancic, D., Nanclares, V., Plebst, C., Starkstein, S.E
Formato: Capítulo de libro
Lenguaje:Inglés
Publicado: American Psychiatric Publishing Inc. 1999
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100 1 |a Manes, F. 
245 1 3 |a An MRI study of the corpus callosum and cerebellum in mentally retarded autistic individuals 
260 |b American Psychiatric Publishing Inc.  |c 1999 
270 1 0 |m Starkstein, S.E.Montaneses 2325, 1428 Buenos Aires, Argentina; email: ses@fleni.org.ar 
506 |2 openaire  |e Política editorial 
504 |a Piven, J., O'Leary, D., Neuroimaging in autism (1997) Child and Adolescent Psychiatry Clinics of North America, 6, pp. 305-323 
504 |a Piven, J., Folstein, S., The genetics of autism (1994) The Neurobiology of Autism, pp. 18-44. , edited by Bauman M. Baltimore, Johns Hopkins University Press 
504 |a Gaffney, G.R., Kuperman, S., Tsai, L.Y., Midsagittal magnetic resonance imaging of autism (1987) Br J Psychiatry, 151, pp. 831-833 
504 |a Egaas, B., Courchesne, E., Saitoh, O., Reduced size of the corpus callosum in autism (1995) Arch Neurol, 52, pp. 794-801 
504 |a Piven, J., Bailey, J., Ranson, B., An MRI study of corpus callosum in autism (1997) Am J Psychiatry, 154, pp. 1051-1056 
504 |a Courchesne, E., Yeung-Courchesne, R., Press, G.A., Hypoplasia of cerebellar vermal lobules VI and VII in autism (1988) N Engl J Med, 318, pp. 1349-1354 
504 |a Filipek, P.A., Richelme, C., Kennedy, D.N., Morphometric analysis of the brain in developmental language disorders and autism (1992) Ann Neurol, 32, p. 475 
504 |a Hashimoto, T., Murakawa, K., Miyazaki, M., Magnetic resonance imaging of the brain structures in the posterior fossa in retarded autism children (1992) Acta Paediatr, 81, pp. 1030-1034 
504 |a Holttum, J.R., Minshew, N.J., Sanders, R.S., Magnetic resonance imaging of the posterior fossa in autism (1992) Biol Psychiatry, 32, pp. 1091-1101 
504 |a Kleiman, M.D., Neff, S., Rosman, N., The brain in infantile autism: Are posterior fossa structures abnormal? (1992) Neurology, 42, pp. 753-760 
504 |a Piven, J., Nehme, E., Simon, J., Magnetic resonance imaging in autism: Measurement of the cerebellum, pons, and fourth ventricle (1992) Biol Psychiatry, 31, pp. 491-504 
504 |a Ritvo, E.R., Garber, J.H., Cerebellar hypoplasia and autism (1988) N Engl J Med, 319, p. 1152 
504 |a Piven, J., Saliba, K., Bailey, J., An MRI study of autism: The cerebellum revisited (1997) Neurology, 49, pp. 546-551 
504 |a Arin, D.M., Bauman, M.L., Kemper, T.L., The distribution of Purkinje cells loss in the cerebellum in autism (1991) Neurology, 41 (SUPPL.), p. 307 
504 |a Courchesne, E., Saitoh, O., Yeung-Courchesne, R., Abnormalities of cerebellar vermian lobules VI and VII in patients with infantile autism: Identification of hypoplastic and hyperplastic subgroups by MR imaging (1994) Am J Roentgenol, 162, pp. 123-130 
504 |a Courchesne, E., Townsend, J., Saitoh, O., The brain in infantile autism: Posterior fossa structures are abnormal (1994) Neurology, 44, pp. 214-223 
504 |a Piven, J., Ardnt, S., The cerebellum in autism (1995) Neurology, 45, pp. 398-399 
504 |a Filipek, P.A., Quantitative magnetic resonance imaging in autism: The cerebellar vermis (1995) Curr Opin Neurol, 8, pp. 134-138 
504 |a Le Couteur, A., Rutter, M., Lord, C., Autism Diagnostic Interview: A standardized investigator-based instrument (1989) J Autism Dev Disord, 19, pp. 363-397 
504 |a Schopler, E., Reichler, R.J., Renner, B.R., (1986) The Childhood Autism Rating Scale (CARS) for Diagnostic Screening and Classification of Autism, , New York, Irvington 
504 |a Arthur, G., (1953) The Arthur Adaptation of the Leiter International Performance Scale, , Chicago, Psychological Services Center Press 
504 |a Raven, J.C., Summers, B., (1986) Manual for Raven's Progressive Matrices and Vocabulary Scales - Research, (3 SUPPL.). , London, Lewis 
504 |a Witelson, S.F., Hand and sex differences in the isthmus and genu of the human corpus callosum (1989) Brain, 112, pp. 799-835 
504 |a Pandya, D.N., Seltzer, B., The topography of commissural fibers (1986) Two Hemispheres - One Brain, pp. 47-73. , edited by Lepore F, Ptito M, Jasper H. New York, Alan R Liss 
504 |a Lacoste, M.C., Kirkpatrick, J.B., Ross, E.D., Topography of the human corpus callosum (1985) J Neuropathol Exp Neurol, 44, pp. 578-591 
504 |a Barkovich, A.J., Norman, D., Anomalies of the corpus callosum: Correlation with further anomalies of the brain (1988) Am J Roentgenol, 151, pp. 171-179 
504 |a Hayakawa, K., Konishi, Y., Matsuda, T., Development and aging of brain midline structures: Assessment with MR imaging (1989) Radiology, 172, pp. 171-177 
504 |a Piven, J., Arndt, S., Bailey, J., Regional brain enlargement in autism: A magnetic resonance imaging study (1996) J Am Acad Child Adolesc Psychiatry, 35, pp. 530-536 
504 |a Ciesielski, K.T., Yanofsky, R., Ludwig, R.N., Hypoplasia of the cerebellar vermis and cognitive deficits in survivors of childhood leukemia (1994) Arch Neurol, 51, pp. 985-993 
504 |a Schaefer, G.B., Thompson Jr., J.N., Bodensteiner, J.B., Hypoplasia of the cerebellar vermis in neurogenetic syndromes (1996) Ann Neurol, 39, pp. 382-385 
520 3 |a The areas of seven subregions of the corpus callosum and three subregions of the cerebellum were examined on midsagittal magnetic resonance imaging scans of 27 low-IQ autistic individuals and 17 nonautistic individuals of comparable mental age. Autistic individuals had a significantly smaller corpus callosum (most marked in the body). No significant between-group differences were found in cerebellum areas. Results demonstrate that abnormalities of the corpus callosum reported in high-functioning autistic individuals are also present in autistic individuals with mental retardation and extend previous reports showing no evidence for a selective hypoplasia of cerebellar lobules VI-VII.  |l eng 
593 |a Montañeses 2325, 1428 Buenos Aires, Argentina 
690 1 0 |a ADOLESCENT 
690 1 0 |a ADULT 
690 1 0 |a ARTICLE 
690 1 0 |a AUTISM 
690 1 0 |a BRAIN SIZE 
690 1 0 |a CEREBELLUM 
690 1 0 |a CHILD 
690 1 0 |a CLINICAL ARTICLE 
690 1 0 |a CONTROLLED STUDY 
690 1 0 |a CORPUS CALLOSUM 
690 1 0 |a FEMALE 
690 1 0 |a HUMAN 
690 1 0 |a MALE 
690 1 0 |a MENTAL DEFICIENCY 
690 1 0 |a NUCLEAR MAGNETIC RESONANCE IMAGING 
690 1 0 |a PRIORITY JOURNAL 
651 4 |a HYPOPLASIA 
700 1 |a Piven, J. 
700 1 |a Vrancic, D. 
700 1 |a Nanclares, V. 
700 1 |a Plebst, C. 
700 1 |a Starkstein, S.E. 
773 0 |d American Psychiatric Publishing Inc., 1999  |g v. 11  |h pp. 470-474  |k n. 4  |p J. Neuropsychiatry Clin. Neurosci.  |x 08950172  |t Journal of Neuropsychiatry and Clinical Neurosciences 
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