Enhanced Glomerulopressin Production and Glomerular Filtration Rate by Amino Acid Infusion in Normal Humans

Amino acid infusion induces a rise in glomerular filtration rate (GFR) in normal subjects, but the mechanism is as yet unknown. Glomerulopressin infused into the renal arteries of rats and dogs increases GFR. The aim of this study was to ascertain whether amino acid infusion raised glomerulopressin...

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Autor principal: Maggiora, E.
Otros Autores: Silberstein, C., Arany, E., Salvidea, J.C, Castillo, E.D, Uranga, J.
Formato: Capítulo de libro
Lenguaje:Inglés
Publicado: 1991
Acceso en línea:Registro en Scopus
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LEADER 11931caa a22012017a 4500
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024 7 |2 scopus  |a 2-s2.0-0026016808 
024 7 |2 cas  |a Amino Acids; glomerulopressin, 39372-38-8; Glucuronates; Glucuronidase, EC 3.2.1.31 
040 |a Scopus  |b spa  |c AR-BaUEN  |d AR-BaUEN 
100 1 |a Maggiora, E. 
245 1 0 |a Enhanced Glomerulopressin Production and Glomerular Filtration Rate by Amino Acid Infusion in Normal Humans 
260 |c 1991 
270 1 0 |m Uranga, J.; Instituto de Biologia y Medicina Experimental, Vuelta de Obligado 2490, 1428 Buenos Aires, Argentina 
506 |2 openaire  |e Política editorial 
504 |a Uranga, J., Some characteristics of hepatic glomerular pressure substance (1971) Am J Physiol, 220, pp. 1617-1620 
504 |a Uranga, J., Fuenzalida, R., Effect of glomerulopressin and a rabbit glomerulopressin-like substance in the rat (1975) Horm Metab Res, 7, pp. 180-184 
504 |a Del Castillo, E., Fuenzalida, R., Rapoport, A.L., Uranga, J., Increased glomerular filtration rate and glomeulopressin activity in diabetic dogs (1977) Horm Metab Res, 9, pp. 46-53 
504 |a Uranga, J., Fuenzalida, R., Rapoport, A.L., Del Castillo, E., Effect of glucagon and glomerulopressin on the renal function of the dog (1979) Horm Metab Res, 11, pp. 275-279 
504 |a Bonetto, R., Arany, E., Del Castillo, E., Uranga, J., Purification of glomerulopressin (1987) Proc Soc Exp Biol Med, 186, pp. 240-245 
504 |a Uranga, J., Arany, E., Aguirre, J., Del Castillo, E., Effect of glomerulopressin on GFR of rats, role of cyclooxygenase inhibitors and saralasin (1990) Acta Physiol Pharmacol Latino Am, 40, pp. 121-125 
504 |a Uranga, J., Rapoport, A.L., Bonetto, R., Arany, E., Del Castillo, E., Influence of insulin and glucagon on the production of glomerulopressin by isolated rat liver (1982) Horm Metab Res, 14, pp. 539-542 
504 |a Del Castillo, E., Fuenzalida, R., Rapoport, A.L., Uranga, J., Effect of glucagon on glomerulopressin production in diabetic dogs (1978) Acta Physiol Latino Am, 28, pp. 179-184 
504 |a Arany, E., Bonetto, R., Uranga, J., Del Castillo, E., Glomerulopressin activity in peripheral blood of newly diagnosed type I (insulin-dependent) diabetic patients and in normal subjects treated with glucagon (1986) Acta Physiol Pharmacol Latino Am, 36, pp. 337-346 
504 |a Schally, A.V., Bowers, C.Y., Reeding, T.W., Baret, J.F., Isolation of thyrotropin releasing factor (TRF) from porcine hypothalamus (1966) Biochem Biophys Res Commun, 25, pp. 165-169 
504 |a Uranga, J., Glomerulopressin: A review (1977) Rev Soc Arg Biol, 53, pp. 1-42 
504 |a Levvy, G.A., The preparation and properties of β-glucuronidase. 4. Inhibition by sugar acids and their lactones (1952) Biochem J, 52, pp. 464-472 
504 |a ter Wee, P.M., Geerlings, W., Rosman, J.B., Sluiter, W.J., van der Geest, S., Donker, A.J.M., Testing renal reserve filtration capacity with an amino acid solution (1983) Nephron, 41, pp. 193-199 
504 |a Ruilope, L.M., Rodicio, J., Garcia Robles, R., Sancho, J., Miranda, B., Granger, J.P., Romero, J.C., Influence of a low-sodium diet on the renal response to amino acid infusions in normal humans (1987) Kidney Int, 31, pp. 992-999 
504 |a Castellino, P., Hunt, W., De Fronzo, R.A., Regulation of renal hemodynamics by plasma amino acid and hormone concentrations (1987) Kidney Int, 32, pp. S-15-S-20. , (suppl 22) 
504 |a Hirschberg, R., Kopple, J.D., Effects of growth hormone on GFR and renal plasma flow in man (1987) Kidney Int, 32, pp. S-21-S-24. , (suppl 22) 
504 |a Hirschberg, R., Zipser, R.D., Slomowitz, L.A., Kopple, J.D., Glucagon and prostaglandins are mediators of amino acid-induced rise in renal hemodynamics (1988) Kidney Int, 33, pp. 1147-1155 
504 |a Pitts, R.F., The effects of infusing glycine and of varying the dietary protein intake on renal hemodynamics in the dog (1944) Am J Physiol, 142, pp. 335-365 
504 |a Hostetter, T.H., Human renal response to a meat meal (1986) Am J Physiol, 250, pp. F613-F618 
504 |a Hostetter, T.H., Mitch, W.E., Protein intake and prevention of chronic diseases (1988) Diseases of the Kidney, p. 3353. , In: Schrier RW, Goltshalk GW, Eds., Boston-Toronto: Little, Brown & Co., Chap 16 
504 |a Dhaene, M., Sabot, J.P., Philippart, Y., Doutrelepont, J.M., Vanher-weghem, J.L., Effects of acute protein loads of different sources on glomerular filtration rate (1987) Kydney Int, 32, pp. S-25-S-28. , (suppl 22) 
504 |a Jolliffe, N., Smith, H.W., The excretion of urine in the dog II. The urea and creatinine clearance on cracker meal diet (1931) Am J Physiol, 99, pp. 101-107 
504 |a Benigni, A., Zoja, C., Remuzzi, A., Orisio, S., Piccinelli, A., Remuzzi, G., Role of prostaglandins in normal and nephrotic rats with diet-induced hyperfiltration (1986) J Lab Clin Med, 108, pp. 230-240 
504 |a Brenner, B.M., Meyer, T.W., Hostetter, T.H., Dietary protein intake and the progressive nature of kidney disease: The role of hemodynamically mediated glomerular injury in the pathogenesis of progressive glomerular sclerosis in aging, renal ablation, and intrinsic renal disease (1982) N Engl J Med, 307, pp. 652-659 
504 |a Alvestrand, A., Bergström, J., Glomerular hyperfiltration after protein ingestion, during glucagon infusion, and in insulin-dependent diabetes is induced by a liver hormone: Deficient production of this hormone in hepatic failure causes hepatorenal syndrome (1984) Lancet, 1, pp. 195-197 
504 |a Premen, A.J., Importance of the liver during glucagon mediated increases in canine renal hemodynamics (1985) Am J Physiol, 249, pp. F319-F322 
504 |a ter Wee, P.M., Rosman, J.B., van der Geest, S., Sluiter, W.J., Donker, A.J.M., Renal haemodynamics during separate and combined infusion of amino acids and dopamine (1986) Kidney Int, 29, pp. 870-874 
504 |a Dratwa, M., Burette, A., Van Gossum, M., Collart, F., Wens, R., Charlier, L., Tielemans, C., Deltenre, M., No rise in glomerular filtration rate after protein loading in cirrhotics (1987) Kidney Int, 32, pp. S32-S34. , (suppl 22) 
504 |a Woods, L.L., Mizelle, H.L., Hall, J.E., Role of the liver in renal hemodynamic response to amino acid infusion (1987) Am J Physiol, 252, pp. F981-F985 
504 |a Premen, A.J., Nature of the renal hemodynamic action of amino acids in dogs (1989) Am J Physiol, 256, pp. F516-F523 
504 |a Bosch, J.P., Saccaggi, A., Lauer, A., Ronco, C., Belledonne, M., Glabman, S., Renal functional reserve in humans. Effect of protein intake on glomerular filtration rate (1983) Am J Med, 75, pp. 943-950 
504 |a Rosen, H., A modified Ninhydrin colorimetric analysis for amino acids (1957) Arch Biochem Biophys, 67, pp. 10-15 
504 |a Uranga, J., The pressure in Bowman's capsule and the occluded ureter of the toad (1965) Acta Physiol Latino Am, 15, pp. 77-85 
504 |a Vargas Fernández, L., (1937) Modificaciones “in vivo” de la actividad de los glomérulos del riñón del sapo, , Mem Prueba Universite Chile, Santiago 
504 |a Sawyer, W.H., Increased renal reabsorption of osmotically free water by the toad (Bufo marinus) in response to neurohypophysial hormones (1957) Am J Physiol, 189, pp. 564-568 
504 |a Uranga, J., Effect of glomerulopressin, oxytocin, and norepinephrine on glomerular pressure in the toad (1973) Gen Comp Endocrinol, 20, pp. 515-521 
504 |a Corvilan, J., Abramow, M., Some effects of human growth hormone on renal homodynamics and on tubular phosphate transport in man (1962) J Clin Invest, 41, pp. 1230-1235 
504 |a Ruilope, L., Rodicio, J., Miranda, B., Garcia Robles, R., Sancho Rof, J., Romero, J.C., Renal effects of amino acid infusions in patients with panhypopituitarism (1988) Hypertension, 11, pp. 557-559 
504 |a Premen, A.J., Hall, J.E., Smith, M.J., Postprandial regulation of renal hemodynamics: Role of pancreatic glucagon (1985) Am J Physiol, 248, pp. F656-F662 
504 |a Bergström, J., Ahlberg, M., Alvestrand, A., Influence of protein intake on renal hemodynamics and plasma hormone concentrations in normal subjects (1985) Acta Med Scand, 217, pp. 189-196 
504 |a Blackard, W.G., Nelson, N.C., Andrews, S.S., Portal and peripheral vein immunoreactive glucagon concentrations after arginine or glucose infusions (1974) Diabetes, 23, pp. 199-202 
520 3 |a Amino acid infusion induces a rise in glomerular filtration rate (GFR) in normal subjects, but the mechanism is as yet unknown. Glomerulopressin infused into the renal arteries of rats and dogs increases GFR. The aim of this study was to ascertain whether amino acid infusion raised glomerulopressin production and GFR. Accordingly, before renal arteriovenography, in 11 potential kidney donors, the caval catheter was introduced into the right hepatic vein and 60-ml blood samples were collected at the beginning and end of each experiment; six patients received amino acid infusion and five a saline infusion. Glomerulopressin in ultrafiltrates from hepatic vein plasma was measured by toad bioassay and GFR determined with diethylenetriamine pentaacetic acid-Tc99. The amino acid-infused group showed significant glomerulopressin activity in ultrafiltrates, as well as a significant GFR increase, whereas in the control group no glomerulopressin activity was observed, and there was no change in GFR. These findings suggest that intravenous amino acid infusion stimulates glomerulopressin production, which may in turn induce an increase in GFR. © 1991, SAGE Publications. All rights reserved.  |l eng 
593 |a Instituto de Biología y Medicina Experimental, Vuelta de Obligado 2490, 1428 Buenos Aires, Argentina 
593 |a Nephrology Service and Radiology Service, Sanatorio Mitre, Bartolomé Mitre 2553, 1039 Buenos Aires, Argentina 
690 1 0 |a AMINO ACID 
690 1 0 |a GLOMERULOPRESSIN 
690 1 0 |a UNCLASSIFIED DRUG 
690 1 0 |a ARTICLE 
690 1 0 |a FEMALE 
690 1 0 |a GLOMERULUS FILTRATION RATE 
690 1 0 |a HUMAN 
690 1 0 |a HUMAN EXPERIMENT 
690 1 0 |a HUMAN TISSUE 
690 1 0 |a KIDNEY DONOR 
690 1 0 |a MALE 
690 1 0 |a NORMAL HUMAN 
690 1 0 |a PRIORITY JOURNAL 
690 1 0 |a ADULT 
690 1 0 |a AMINO ACIDS 
690 1 0 |a ANALYSIS OF VARIANCE 
690 1 0 |a FEMALE 
690 1 0 |a GLOMERULAR FILTRATION RATE 
690 1 0 |a GLUCURONATES 
690 1 0 |a GLUCURONIDASE 
690 1 0 |a HUMAN 
690 1 0 |a INFUSIONS, INTRAVENOUS 
690 1 0 |a KIDNEY GLOMERULUS 
690 1 0 |a MALE 
690 1 0 |a REGIONAL BLOOD FLOW 
690 1 0 |a SUPPORT, NON-U.S. GOV'T 
690 1 0 |a ANURA 
690 1 0 |a CANIS FAMILIARIS 
690 1 0 |a GLOMERULUS 
700 1 |a Silberstein, C. 
700 1 |a Arany, E. 
700 1 |a Salvidea, J.C. 
700 1 |a Castillo, E.D. 
700 1 |a Uranga, J. 
773 0 |d 1991  |g v. 196  |h pp. 170-174  |k n. 2  |p Proc. Soc. Exp. Biol. Med.  |x 00379727  |w (AR-BaUEN)CENRE-2685  |t Proceedings of the Society for Experimental Biology and Medicine 
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