Chemiluminescence production by neutrophils and immune complex levels in cancer patients

We studied the production of chemiluminescence (CL) by peripheral blood neutrophils from 24 normal subjects, 13 lung cancer patients with clinical stages (CS) III and IV, and 27 breast cancer patients with CS II, III, and IV. Evaluations were made before chemo- and radiotherapy treatments. CL was ex...

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Autor principal: Chasseing, N.A
Otros Autores: Barañao, R.I, Fernández, O., Bordenave, H., Rumi, L.S
Formato: Capítulo de libro
Lenguaje:Inglés
Publicado: Informa Healthcare 1993
Acceso en línea:Registro en Scopus
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024 7 |2 scopus  |a 2-s2.0-0027306123 
024 7 |2 cas  |a zymosan, 58856-93-2, 68652-43-7, 9010-72-4; Antigen-Antibody Complex; Opsonins; Oxygen, 7782-44-7; Polyethylene Glycols; Zymosan, 9010-72-4 
040 |a Scopus  |b spa  |c AR-BaUEN  |d AR-BaUEN 
030 |a CINVD 
100 1 |a Chasseing, N.A. 
245 1 0 |a Chemiluminescence production by neutrophils and immune complex levels in cancer patients 
260 |b Informa Healthcare  |c 1993 
270 1 0 |m Chasseing, N.A.; Lnstituto de Biologia y Medicina Experimental, Obligado 2490, 1428, Buenos Aires, Argentina 
506 |2 openaire  |e Política editorial 
504 |a Dvorak, A.M., Connell, A.B., Proppe, K., Dvorak, H.F., Immunologic rejection of mammary adenocarcinoma (TA3-ST) in C57BL7 6 mice. Participation of neutrophils and activated macrophages with fibrin formation (1978) J Immunol, 120, pp. 1240-1248 
504 |a Fisher, B., Saffer, E.A., Tumor cell cytotoxicity by granulocytes from peripheral blood of tumor-bearing mice (1978) J Natl Cancer Inst, 60, pp. 687-691 
504 |a Levy, P.C., Shaw, C.M., Lobuglio, A.F., Human monocyte, lymphocyte and granulocyte antibody-dependent cell-mediated cytotoxicity toward tumor cells. General characteristics of cytolysis (1979) J Immunol, 123, pp. 594-599 
504 |a Lichtenstein, A., Spontaneous tumor cytolysis mediated by inflammatory neutrophils dependence upon divalent cations and reduced oxygen intermediates (1986) Blood, 67, pp. 657-665 
504 |a Cheung, K., Archibald, A.C., Robinson, M.F., The origin of chemilu-minescence produced by neutrophils stimulated by opsonized zymosan (1983) J Immunol, 130, pp. 2324-2329 
504 |a Maridonneau-Parini, I., Tringale, S.M., Tauber, A.I., Identification of distinct activation pathways of the human neutrophil NADPH-oxidase (1986) J Immunol, 137, pp. 2925-2929 
504 |a Johnston, R.B., Jr., Lehmeyer, J.E., Elaboration of toxic oxygen byproducts by neutrophils in a model of immune complex disease (1976) J Clin Invest, 57, pp. 836-841 
504 |a Griffin, F.M., Jr., Effects of soluble immune complexes on Fc receptor and C3b receptor-mediated phagocytosis by macrophages (1980) J Exp Med, 152, pp. 905-919 
504 |a Starkebaum, E., Stevens, D.L., Henry, C., Stimulation of human neutrophil chemiluminescence by soluble immune complexes and antibodies to neutrophils (1981) J Lab Clin Med, 98, pp. 280-291 
504 |a Doll, N.J., Wilson, M.R., Salvaggio, J.E., Inhibition of polymorphonuclear leukocyte chemiluminescence for detection of immune complexes in human sera (1980) J Clin Invest, 66, pp. 457-464 
504 |a Allen, R.C., Stjernholm, R.L., Reed, M.A., Correlation of metabolic and chemiluminescent responses of granulocytes from three female siblings with chronic granulomatous disease (1977) J Infect Dis, 136, pp. 510-518 
504 |a Andersen, B.R., Amirault, H.J., Important variables in granulocyte chemiluminescence (1979) Proc Soc Exp Biol Med, 162, pp. 139-145 
504 |a Creighton, W.D., Lambert, P.H., Miescher, P.A., Detection of antibodies and soluble antigen-antibody complexes by precipitation with polyethylene glycol (1973) J Immunol, 111, pp. 1219-1227 
504 |a Chenson, B.D., Christensen, R.L., Sperling, R., The origin of the chemiluminescence of phagocytosing granulocytes (1976) J Clin Invest, 58, pp. 789-796 
504 |a McPhail, L.C., Snyderman, B., Activation of respiratory burst enzyme in human polymorphonuclear leukocytes by chemoattrac-tants and other soluble stimuli. Evidence that the same oxidase is activated by different transductional mechanisms (1983) J Clin Invest, 72, pp. 192-200 
504 |a De Chatelet, R., Shirley, P.S., Johnston, R.B., Jr., Effect of phorbol myristate acetate on the oxidative metabolism of human polymorphonuclear leukocytes (1976) Blood, 47, pp. 545-554 
504 |a Braun, D.P., Harris, J.E., Maximovich, S., Chemiluminescence in peripheral blood mononuclear cells of solid tumor cancer patients (1981) Cancer Immunol Immunother, 12, pp. 31-37 
504 |a Starkebaum, G., Jimenez, R.A., Arend, W.P., Effect of immune complexes on human neutrophil phagocytic function (1982) J Immunol, 128, pp. 141-147 
520 3 |a We studied the production of chemiluminescence (CL) by peripheral blood neutrophils from 24 normal subjects, 13 lung cancer patients with clinical stages (CS) III and IV, and 27 breast cancer patients with CS II, III, and IV. Evaluations were made before chemo- and radiotherapy treatments. CL was expressed as: baseline of the record background activity; area under the curve (AUC) of opsonized zymosan response; maximum peak (MP) response; time to MP (TMP); and total time (TT). Simultaneously, circulating immune complexes (CIC) in sera were evaluated by polyethylene glycol precipitation technique. The results demonstrated that lung cancer patients with CS III had an increase of TMP and TT values, while breast cancer patients with CS IV showed the lowest values of AUC and MP compared with the control group. The CIC levels were increased in all the cancer patients. There was no correlation between the baseline CL activity and the levels of immune complexes. © 1993 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.  |l eng 
593 |a Consejo Nacional de Investigacíones Cientlficas y Técnicas de la, Repúblics Argentina, (CONICET), Argentina 
593 |a Instituto de Biología y Medicina Experimental, Obligado 2490 1428, Buenos Aires, Argentina 
593 |a Department of Oncology, Hospital Zonal de Agudos I. Iriarte, Quilmes, Pcia. de, Buenos Aires, Argentina 
690 1 0 |a ENDOGENOUS COMPOUND 
690 1 0 |a ZYMOSAN 
690 1 0 |a ANTIGEN ANTIBODY COMPLEX 
690 1 0 |a ARTICLE 
690 1 0 |a BREAST CANCER 
690 1 0 |a CHEMOLUMINESCENCE 
690 1 0 |a CLINICAL ARTICLE 
690 1 0 |a CONTROLLED STUDY 
690 1 0 |a FEMALE 
690 1 0 |a HUMAN 
690 1 0 |a HUMAN CELL 
690 1 0 |a LUNG CANCER 
690 1 0 |a MALE 
690 1 0 |a NEUTROPHIL 
690 1 0 |a ANTIGEN-ANTIBODY COMPLEX 
690 1 0 |a BREAST NEOPLASMS 
690 1 0 |a CHEMILUMINESCENCE 
690 1 0 |a HUMAN 
690 1 0 |a LUNG NEOPLASMS 
690 1 0 |a NEUTROPHILS 
690 1 0 |a OPSONINS 
690 1 0 |a OXYGEN 
690 1 0 |a POLYETHYLENE GLYCOLS 
690 1 0 |a ZYMOSAN 
700 1 |a Barañao, R.I. 
700 1 |a Fernández, O. 
700 1 |a Bordenave, H. 
700 1 |a Rumi, L.S. 
773 0 |d Informa Healthcare, 1993  |g v. 11  |h pp. 517-522  |k n. 5  |p Cancer Invest.  |x 07357907  |w (AR-BaUEN)CENRE-4107  |t Cancer Investigation 
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