Prostaglandins alter the 3H-noradrenaline metabolism by the isolated rat uterus from ovariectiomized animals
The influence of prostaglandins (PGs) on the metabolism of 3H-noradrenaline in isolated uterine, horns from ovariectomized rats exposed to acetylsalicylic acid was explored. PGE1 and PGE2 (10 nM) increased both the total tritium and the 3H-O-methylated deaminated metabolites from the spontaneous out...
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| Formato: | Capítulo de libro |
| Lenguaje: | Inglés |
| Publicado: |
1982
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| Acceso en línea: | Registro en Scopus DOI Handle Registro en la Biblioteca Digital |
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| LEADER | 08405caa a22011897a 4500 | ||
|---|---|---|---|
| 001 | PAPER-18436 | ||
| 003 | AR-BaUEN | ||
| 005 | 20230518204948.0 | ||
| 008 | 190411s1982 xx ||||fo|||| 00| 0 eng|d | ||
| 024 | 7 | |2 scopus |a 2-s2.0-0020001129 | |
| 024 | 7 | |2 cas |a 3,4 dihydroxyphenylethylene glycol, 3343-19-9; 4 hydroxy 3 methoxyphenylethylene glycol, 534-82-7; noradrenalin, 1407-84-7, 51-41-2; normetadrenalin, 97-31-4; prostacyclin, 35121-78-9, 61849-14-7; prostaglandin E, 11042-70-9; prostaglandin E1, 745-65-3; prostaglandin E2, 363-24-6; acetylsalicylic acid, 493-53-8, 50-78-2, 53663-74-4, 53664-49-6, 63781-77-1; prostaglandin F2 alpha, 551-11-1; Alprostadil, 745-65-3; dihydroxyphenylethylene glycol, 3343-19-9; Dinoprostone, 363-24-6; Epoprostenol, 35121-78-9; Methoxyhydroxyphenylglycol, 534-82-7; Norepinephrine, 51-41-2; Normetanephrine, 97-31-4; Prostaglandins E; Prostaglandins | |
| 040 | |a Scopus |b spa |c AR-BaUEN |d AR-BaUEN | ||
| 030 | |a PLMED | ||
| 100 | 1 | |a Fernández Pardal, J. | |
| 245 | 1 | 0 | |a Prostaglandins alter the 3H-noradrenaline metabolism by the isolated rat uterus from ovariectiomized animals |
| 260 | |c 1982 | ||
| 270 | 1 | 0 | |m Gimeno, A.L.; Centro de Estudios Farmacológicos y de Principios, Naturales (CEFAPRIN), Consejo Nacional de Investigaciones Cientificas y Tecnicas de la Republica Argentina (CONICET). Serr, 1414 Buenos Aires, Argentina |
| 506 | |2 openaire |e Política editorial | ||
| 504 | |a Ham, Cirillo, Zanetti, Kuelh, Estrogen direct synthesis of specific prostaglandins in uterus (1975) Proc. Nat. Acad. Sci. U.S.A., 72, p. 1420 | ||
| 504 | |a Gimeno, Sterin-Speziale, Landa, Bonacossa, Gimeno, Is the spontaneous motility of isolated rat uterus controlled by prostaglandin E? (1979) Prostaglandins, 17, p. 673 | ||
| 504 | |a Kroeger, Effect of tissue adenosine 3′5′-monophosphate on the potassium contracture of myometrium: role of endogenous norepinephrine (1979) J. Pharmacol. Exp. Ther., 210, p. 82 | ||
| 504 | |a Hervonen, Kanerva, Lietzen, Histochemically demonstrable catecholamines and cholinesterases of the rat uterus during estrus cycle, pregnancy and after estrogen treatment (1973) Acta Physiol. Scand., 87, p. 283 | ||
| 504 | |a Hedqvist, Basic nechanisms of prostaglandin action on autonomic neurotransmission (1977) Ann. Rev. Pharmacol. Toxicol., 17, p. 259 | ||
| 504 | |a Fernández Pardal, Granata, Barrio, Gimeno, Metabolism of 3H-noradrenaline released from isolated rat hypothalamus by extracts of black widow spider glands (1980) Naunyn-Schmiedeberg's Archives of Pharmacology, 313, p. 27 | ||
| 504 | |a Graefe, Stefano, Langer, Preferential metabolism (−)-3H-norepinephrine through the deaminated glycol in the rat vas deferens (1973) Biochem. Pharmacol., 22, p. 1147 | ||
| 504 | |a Bergström, Dressler, Krabisch, Ryhage, Sjövall, The isolation and structure of a smooth muscle stimulating factor in normal, sheep and pig lungs (1962) Ark. Kemi, 20, p. 63 | ||
| 504 | |a Samuelsson, Identification of a smooth muscle stimulating factor in bovine brain (1964) Biochim. Biophys. Acta (Amst.), 84, p. 218 | ||
| 504 | |a Flower, Drugs which inhibit prostaglandin biosynthesis (1974) Pharmacol. Rev., 26, p. 33 | ||
| 504 | |a Taube, Starke, Borowski, Presynaptic receptor system on the noradrenergic neurones of rat brain (1977) Naunyn Schmiedeberg's Arch. Pharmacol., 299, p. 123 | ||
| 504 | |a Stjärne, Kinetics of secretion of sympathetic neurotransmitter as a function of external calcium mechanism of inhibitory effect of prostaglandin E (1973) Acta Physiologica Scandinavica, 87, p. 428 | ||
| 504 | |a Westfall, Brasted, Specificity of blockade of the nicotine-induced release of 3H-norepinephrine from adrenergic neurons of the guinea-pig heart by various pharmacological agents (1974) J. Pharmacol. Exp. Ther., 189, p. 659 | ||
| 504 | |a Hedqvist, Antagonism by calcium of the inhibitory action of prostaglandin E2 on sympathetic neurotransmission in the cat spleen (1970) Acta Physiol. Scand., 80, p. 269 | ||
| 504 | |a Miele, Lack of effect of prostaglandin E1 and F1 on adrenomedullary catecholamine secretion, evoked by various agents (1969) Ann. Rev. Pharmacol. Toxicol., 17, p. 259 | ||
| 504 | |a Bhagat, Dhalla, Ginn, La Montagna, Montier, Modification by prostaglandin E2 (PGE2) of the response of guinea-pig isolated vasa deferentia, and atria, to adrenergic stimuli (1972) British Journal of Pharmacology, 44, p. 687 | ||
| 504 | |a Moncada, Gryglewsky, Bunting, Vane, An enzyme isolated from arteries transforms prostaglandin endoperoxides, to an unstable substance that inhibits platelet aggregation (1976) Nature (Lond.), 263, p. 663 | ||
| 504 | |a Borda, Ganga, Gimeno, Gimeno, An adrenergic participation subserving a positive inotropism and chronotropism of prostacyclin on isolated rat atria. (1979) Experientia, 35, p. 529 | ||
| 520 | 3 | |a The influence of prostaglandins (PGs) on the metabolism of 3H-noradrenaline in isolated uterine, horns from ovariectomized rats exposed to acetylsalicylic acid was explored. PGE1 and PGE2 (10 nM) increased both the total tritium and the 3H-O-methylated deaminated metabolites from the spontaneous outflow. PGE2 augmented 3H-normetanephrine whereas PGE1 reduced the 3H-3,4-dihydroxyphenylglycol fraction. The 3H-noradrenaline fraction from the spontaneous outflow of tritium was enhanced by PGE2 and PGI2 (10 nM). On the other hand PGF2α (10 nM-1 uM) did not change the metabolism of 3H-noradrenaline. The present findings suggest a possible modulation of noradrenaline metabolism by some PGs on the isolated rat uterus from ovariectomized rats. © 1982 Longman Group Ltd. |l eng | |
| 593 | |a Centro de Estudios Farmacológicos y de Principios, Naturales (CEFAPRIN), Consejo Nacional de Investigaciones Cientificas y Tecnicas de la Republica Argentina (CONICET). Serr, 1414 Buenos Aires, Argentina | ||
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| 700 | 1 | |a Gimeno, M.F. | |
| 700 | 1 | |a Gimeno, A.L. | |
| 773 | 0 | |d 1982 |g v. 9 |h pp. 341-348 |k n. 3 |p Prostaglandins Leukotrienes Med. |x 02621746 |t Prostaglandins, Leukotrienes and Medicine | |
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