The inhibition of insect chitin synthesis by tunicamycin

The conversion of [14C]-labeled glucosamine to [14C]-labeled insect chitin was inhibited by tunicamycin, a nucleoside antibiotic which specifically blocks the biosynthesis of dolichyl diphosphate N-Acetylglucosamine. A method of short-term culturing is described for the analysis of chitin and glycon...

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Autor principal: Quesada-Allue, L.A
Formato: Capítulo de libro
Lenguaje:Inglés
Publicado: 1982
Acceso en línea:Registro en Scopus
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Registro en la Biblioteca Digital
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024 7 |2 cas  |a chitin, 1398-61-4; polyoxin D, 22976-86-9; tunicamycin, 11089-65-9; Carbon Radioisotopes; Chitin, 1398-61-4; Glucosamine, 3416-24-8; Tunicamycin, 11089-65-9 
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030 |a BBRCA 
100 1 |a Quesada-Allue, L.A. 
245 1 4 |a The inhibition of insect chitin synthesis by tunicamycin 
260 |c 1982 
270 1 0 |m Quesada-Allue, L.A.; Instituto de Investigaciones Bioquimicas Fundacion Campomar Obligado 2490, 1428 Buenos Aires, Argentina 
506 |2 openaire  |e Política editorial 
504 |a Locke, (1976) The Insect Integument, pp. 237-258. , H.R. Hepburn, Elsevier, Oxford 
504 |a Neville, (1975) Biology of the Arthropod Cuticle, , Springer Verlag, Amsterdam 
504 |a Glenn Richards, (1978) Biochemistry of Insects, pp. 205-232. , M. Rockstein, Academic Press, Berlin 
504 |a Hunt, (1970) Polysaccharide-Protein Complexes in Invertebrates, , Academic Press, N. York 
504 |a Hackman, (1974) The Physiology of Insecta, pp. 216-270. , M. Rockstein, Academic Press, London 
504 |a Strout, Lipke, Geoghegan, (1976) The Insect Integument, pp. 43-61. , H.R. Hepburn, Elsevier, New York 
504 |a Keller, Cabib, (1971) J. Biol. Chem., 246, pp. 160-166 
504 |a Rousset-Hall, Gooday, A Kinetic Study of a Solubilized Chitin Synthetase Preparation from Coprinus cinereus (1975) Journal of General Microbiology, 89, pp. 146-154 
504 |a Ruiz-Herrera, Lopez-Romero, Bartnicki-Garcia, (1977) J. Biol. Chem., 252, pp. 3338-3343 
504 |a Duran, Cabib, (1978) J. Biol. Chem., 253, pp. 4419-4425 
504 |a Muzzarelli, (1978) Chitin, , Academic Press, Amsterdam 
504 |a Mayer, Chen, De Loach, (1980) Insect Biochem., 10, pp. 549-556 
504 |a Candy, Kilby, (1962) J. Exp. Biol., 39, pp. 129-140 
504 |a Vardanis, (1976) Life Sci., 19, pp. 1949-1956 
504 |a Oberlander, Ferkovich, Leach, Van Essen, (1980) Wilhelm Roux's Archives, 188, pp. 81-86 
504 |a Marks, Insect Tissue Culture: An Overview, 1971-1978 (1980) Annual Review of Entomology, 25, pp. 73-101 
504 |a Silvert, Fristrom, (1980) Insect Biochem., 10, pp. 341-355 
504 |a Najjar, Casida, (1978) Science, 200, pp. 1499-1500 
504 |a Van Eck, (1979) Insect Biochem., 9, pp. 295-300 
504 |a Hettick, Bade, (1978) MIT Sea Grant Report 78-7, , Muzzarelli, Panser, MIT, New York 
504 |a Jaworski, Wang, Marco, (1963) Nature, 198, pp. 790-791 
504 |a Porter, Jaworski, (1965) J. Insect Physiol., 11, pp. 1151-1160 
504 |a Quesada-Allue, Marechal, Belocopitow, Acta Physiol. Latinoam. (1976) Acta Physiol. Latinoam., 26, pp. 349-363 
504 |a Cohen, Casida, (1980) Pestic. Biochem. Physiol., 13, pp. 121-128 
504 |a Cohen, Casida, (1980) Pestic. Biochem. Physiol., 13, pp. 129-136 
504 |a Quesada-Allue, (1978) Ph.D. Thesis, , University of Buenos Aires, Cambridge 
504 |a Quesada-Allue, Belocopitow, (1978) Eur. J. Biochem., 88, pp. 529-541 
504 |a McMurrough, Bartnicki-Garcia, (1971) J. Biol. Chem., 246, pp. 4008-4016 
504 |a Horst, (1981) J. Biol. Chem., 256, pp. 1412-1419 
504 |a Quesada-Allue, (1981) Mol. Cell. Biochem., 33, pp. 149-155 
504 |a Quesada-Allue, (1973) Master Dissertation, , University of Buenos Aires 
504 |a Elbein, (1981) T.I.B.S., 6, pp. 219-221 
504 |a Quesada-Allue, Belocopitow, Marechal, (1975) Biochem. Biophys. Res. Commun., 66, pp. 1201-1208 
504 |a Belocopitow, Marechal, Quesada-Allue, (1977) Mol. Cell. Biochem., 16, pp. 127-134 
504 |a Folch, Lees, Sloane, (1967) J. Biol. Chem., 226, pp. 497-509 
504 |a Behrens, Parodi, Leloir, (1971) Proc. Natn. Acad. Sci. USA, 68, pp. 2857-2860 
504 |a Parodi, Behrens, Leloir, Carminatti, (1972) Proc. Natl. Acad. U.S.A., 69, pp. 3268-3272 
504 |a Zinn, Platner, Carlson, (1977) The Glycoconjugates, 1, pp. 69-85. , Horowitz, Pigman, Academic Press 
504 |a Nishioka, Fujita, Nakajina, Effect of Chitin Synthesis Inhibitors on Cuticle Formation of the Cultured Integument of Chilo suppressalis (1979) Journal of Pesticide Science, 4, pp. 367-374 
504 |a Parodi, Leloir, (1976) Biochem. Biophys. Acta, 559, pp. 1-37 
504 |a Selintrennikoff, (1979) Arch. Biochem. Biophys., 195, pp. 244-263 
520 3 |a The conversion of [14C]-labeled glucosamine to [14C]-labeled insect chitin was inhibited by tunicamycin, a nucleoside antibiotic which specifically blocks the biosynthesis of dolichyl diphosphate N-Acetylglucosamine. A method of short-term culturing is described for the analysis of chitin and glyconjugates biosynthesis by epidermal tissue of Triatoma infestans. © 1982 Academic Press, Inc.  |l eng 
536 |a Detalles de la financiación: Consejo Nacional de Investigaciones Científicas y Técnicas 
536 |a Detalles de la financiación: I am indebted to Professor Dr. ~ L.F. Leloir for his continued guidance and support and to Dr. N. Judewicz for the critical reading of the manuscript. I wish to thank the other members of the Instituto de Investigaciones Bioquimi-cas for many helpful discussions. I am a Career Investigator of the Consejo Nacional de Investigaciones Cientificas y Tecnicas (Argentina). 
593 |a Instituto de Investigaciones Bioquimicas Fundacion Campomar Obligado 2490, 1428 Buenos Aires, Argentina 
690 1 0 |a CHITIN 
690 1 0 |a POLYOXIN D 
690 1 0 |a TUNICAMYCIN 
690 1 0 |a DRUG SYNTHESIS 
690 1 0 |a GLUCOSAMINE C 14 
690 1 0 |a GLUCOSE C 14 
690 1 0 |a NONHUMAN 
690 1 0 |a ANIMAL 
690 1 0 |a CARBON RADIOISOTOPES 
690 1 0 |a CHITIN 
690 1 0 |a GLUCOSAMINE 
690 1 0 |a HEMIPTERA 
690 1 0 |a KINETICS 
690 1 0 |a SUPPORT, NON-U.S. GOV'T 
690 1 0 |a TUNICAMYCIN 
773 0 |d 1982  |g v. 105  |h pp. 312-319  |k n. 1  |p Biochem. Biophys. Res. Commun.  |x 0006291X  |w (AR-BaUEN)CENRE-905  |t Biochemical and Biophysical Research Communications 
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