Modulation of glucocorticoid effect in thymus of adrenalectomized-diabetic rat
Cellular receptors to glucocorticoids and the effect of dexamethasone and corticosterone on 3H-uridine incorporation into the acid-insoluble fraction were studied in thymocytes from adrenalectomized-diabetic rats and adrenalectomized ones. An increase in the dissociation constant of the hormone-rece...
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| Formato: | Capítulo de libro |
| Lenguaje: | Inglés |
| Publicado: |
1984
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| Acceso en línea: | Registro en Scopus DOI Handle Registro en la Biblioteca Digital |
| Aporte de: | Registro referencial: Solicitar el recurso aquí |
| LEADER | 02776caa a22005417a 4500 | ||
|---|---|---|---|
| 001 | PAPER-18302 | ||
| 003 | AR-BaUEN | ||
| 005 | 20230518204940.0 | ||
| 008 | 190411s1984 xx ||||fo|||| 00| 0 eng|d | ||
| 024 | 7 | |2 scopus |a 2-s2.0-0021366812 | |
| 024 | 7 | |2 cas |a corticosterone, 50-22-6; dexamethasone, 50-02-2; estradiol, 50-28-2; progesterone, 57-83-0; streptozocin, 18883-66-4; testosterone, 58-22-0 | |
| 040 | |a Scopus |b spa |c AR-BaUEN |d AR-BaUEN | ||
| 030 | |a HMMRA | ||
| 100 | 1 | |a Roldan, A. | |
| 245 | 1 | 0 | |a Modulation of glucocorticoid effect in thymus of adrenalectomized-diabetic rat |
| 260 | |c 1984 | ||
| 506 | |2 openaire |e Política editorial | ||
| 520 | 3 | |a Cellular receptors to glucocorticoids and the effect of dexamethasone and corticosterone on 3H-uridine incorporation into the acid-insoluble fraction were studied in thymocytes from adrenalectomized-diabetic rats and adrenalectomized ones. An increase in the dissociation constant of the hormone-receptor plot was observed when adrenalectomized-diabetic animals were compared to adrenalectomized controls. Meanwhile decreasing concentrations of dexamethasone and corticosterone below receptors saturation, were less active as inhibitor of 3H-uridine incorporation into RNA by thymocytes from adrenalectomized-diabetic than from adrenalectomized ones. |l eng | |
| 593 | |a Instituto de Biologia y Medicina Experimental, 1428 Buenos Aires, Argentina | ||
| 690 | 1 | 0 | |a CORTICOSTERONE |
| 690 | 1 | 0 | |a DEXAMETHASONE |
| 690 | 1 | 0 | |a DEXAMETHASONE H 3 |
| 690 | 1 | 0 | |a ESTRADIOL |
| 690 | 1 | 0 | |a GLUCOCORTICOID |
| 690 | 1 | 0 | |a PROGESTERONE |
| 690 | 1 | 0 | |a STREPTOZOCIN |
| 690 | 1 | 0 | |a TESTOSTERONE |
| 690 | 1 | 0 | |a UNCLASSIFIED DRUG |
| 690 | 1 | 0 | |a URIDINE H 3 |
| 690 | 1 | 0 | |a ADRENALECTOMY |
| 690 | 1 | 0 | |a ANIMAL MODEL |
| 690 | 1 | 0 | |a ARTICLE |
| 690 | 1 | 0 | |a DIABETES MELLITUS |
| 690 | 1 | 0 | |a DRUG EFFICACY |
| 690 | 1 | 0 | |a ENDOCRINE SYSTEM |
| 690 | 1 | 0 | |a NONHUMAN |
| 690 | 1 | 0 | |a RAT |
| 690 | 1 | 0 | |a THYMUS |
| 690 | 1 | 0 | |a ANIMALIA |
| 700 | 1 | |a Castillo, M.B. | |
| 773 | 0 | |d 1984 |g v. 16 |h pp. 17-21 |k n. 1 |p HORM. METAB. RES. |x 00185043 |t Hormone and Metabolic Research | |
| 856 | 4 | 1 | |u https://www.scopus.com/inward/record.uri?eid=2-s2.0-0021366812&doi=10.1055%2fs-2007-1014684&partnerID=40&md5=0b20aa1e5bdb3c5b026d8dedd77f9e4b |y Registro en Scopus |
| 856 | 4 | 0 | |u https://doi.org/10.1055/s-2007-1014684 |y DOI |
| 856 | 4 | 0 | |u https://hdl.handle.net/20.500.12110/paper_00185043_v16_n1_p17_Roldan |y Handle |
| 856 | 4 | 0 | |u https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00185043_v16_n1_p17_Roldan |y Registro en la Biblioteca Digital |
| 961 | |a paper_00185043_v16_n1_p17_Roldan |b paper |c PE | ||
| 962 | |a info:eu-repo/semantics/article |a info:ar-repo/semantics/artículo |b info:eu-repo/semantics/publishedVersion | ||
| 999 | |c 79255 | ||