Effect of naloxone on the nocturnal rise of rat pineal melatonin content
Rats exposed to 14 light: 10 h dark photoperiods were given naloxone hydrochloride (10 mg/kg) s.c. 2 h before and 5 h after the lights were turned off. A smaller noctúrnal pineal melatonin peak, as well as a slower decrease from peak values were observed in naloxone-treated rats. Naloxone (up to 10-...
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| Formato: | Capítulo de libro |
| Lenguaje: | Inglés |
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1984
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| Acceso en línea: | Registro en Scopus DOI Handle Registro en la Biblioteca Digital |
| Aporte de: | Registro referencial: Solicitar el recurso aquí |
| LEADER | 06283caa a22008537a 4500 | ||
|---|---|---|---|
| 001 | PAPER-18283 | ||
| 003 | AR-BaUEN | ||
| 005 | 20230518204939.0 | ||
| 008 | 190411s1984 xx ||||fo|||| 00| 0 eng|d | ||
| 024 | 7 | |2 scopus |a 2-s2.0-0021331402 | |
| 024 | 7 | |2 cas |a endorphin, 60118-07-2; melatonin, 73-31-4; naloxone, 357-08-4, 465-65-6; noradrenalin, 1407-84-7, 51-41-2; Melatonin, 73-31-4; Naloxone, 465-65-6 | |
| 040 | |a Scopus |b spa |c AR-BaUEN |d AR-BaUEN | ||
| 030 | |a EJPHA | ||
| 100 | 1 | |a Lowenstein, P.R. | |
| 245 | 1 | 0 | |a Effect of naloxone on the nocturnal rise of rat pineal melatonin content |
| 260 | |c 1984 | ||
| 270 | 1 | 0 | |m Lowenstein, P.R.; Centro de Estudios Farmacológicos y de Principios Naturales (CEFAPRIN), Serrano 665/669, 1414 Buenos Aires, Argentina |
| 506 | |2 openaire |e Política editorial | ||
| 504 | |a Cardinali, Gejman, Ritta, Further evidence of adrenergic control of translocation and intracellular levels of estrogen receptor in rat pineal gland (1983) Endocrinology, 112, p. 492 | ||
| 504 | |a Cardinali, Ritta, Pereyra, Gonzalez Solveyra, Role of prostaglandins in rat pineal neuroeffector junction. Changes in melatonin and nirepinephrine release in vitro (1982) Endocrinology, 111, p. 530 | ||
| 504 | |a Dafny, Burks, Opiate and endocrine interaction: morphine effects on hypothalamus and pineal body (1976) Neuroendocrinology, 22, p. 72 | ||
| 504 | |a Geffard, Gaffori, Chaveau, Muyard, Le Moal, Dramatic increase in pineal gland melatonin levels in the rat after subcutaneous injection of des-tyrosine gamma-endorphin (1981) Neurosci Lett., 27, p. 329 | ||
| 504 | |a Kavaliers, Hirst, Teskey, Ageing, opioid analgesia and the pineal gland (1983) Life Sci., 32, p. 2279 | ||
| 504 | |a Lakin, Miller, Statt, Winters, Involvement of the pineal gland and melatonin in murine analgesia (1981) Life Sci., 29, p. 2543 | ||
| 504 | |a Moore, The suprachiasmatic nucleus and the organization of a circadian system (1982) Trends Neurosci., 5, p. 404 | ||
| 504 | |a Vuolteenaho, Vakkuri, Leppäluoto, Wide distribution of β-endorphin-like immunoreactivity in extrapituitary tissues of rat (1980) Life Sci., 27, p. 57 | ||
| 504 | |a Wilson, Klein, Chang, Casparis, Viveros, Yang, Are opioid peptides cotransmitters in noradrenergic vesicles of sympathetic nerves? (1980) Nature, 288, p. 707 | ||
| 504 | |a Zatz, Brownstein, Central depressants rapidly reduce nocturnal serotonin-N-acetyltransferase activity in the rat pineal gland (1979) Brain Res., 160, p. 381 | ||
| 520 | 3 | |a Rats exposed to 14 light: 10 h dark photoperiods were given naloxone hydrochloride (10 mg/kg) s.c. 2 h before and 5 h after the lights were turned off. A smaller noctúrnal pineal melatonin peak, as well as a slower decrease from peak values were observed in naloxone-treated rats. Naloxone (up to 10-4M) did not affect either in vitro rat pineal melatonin content or 3H-labeled transmitter release in glands previously incubated with [3H]norepinephrine. Hence a central, rather than a peripheral opioid synapse appears to be involved in naloxone effect on nocturnal melatonin increase. © 1984. |l eng | |
| 536 | |a Detalles de la financiación: Consejo Nacional de Investigaciones Científicas y Técnicas | ||
| 536 | |a Detalles de la financiación: Consejo Nacional de Investigaciones Científicas y Técnicas | ||
| 536 | |a Detalles de la financiación: A number of publications suggest a role of endogenous opioids in the regulation of pineal function. In rats administration of either morphine or the opioid antagonist naloxone changed in an opposite way the amplitude of sensory-evoked electrical potentials in pineal gland (Dafny and Burks, 1976). A number of central depressants including morphine caused a transient decrease of peak levels of pineal serotonin-N-acetyltransferase activity when injected to rats at night (Zatz and Brownstein, 1979). Administration of des-tyrosine-y endorphin to rats elicited a significant increase in pineal melatonin content (Geffard et al., 1981). Since fl-endorphin-like immunoreactivity was detectable in rat pineal glands (Vuolteenaho et al., * This work was supported by grant no 6638 from the Consejo Nacional de Investigaciones Cientificas y T~cnicas (CONICET), Argentina. ** Research Fellow, CONICET. *** Established Investigator, CONICET. To whom all cor-respondence should be addressed. | ||
| 593 | |a Centro de Estudios Farmacológicos y de Principios Naturales (CEFAPRIN), Serrano 665/669, 1414 Buenos Aires, Argentina | ||
| 690 | 1 | 0 | |a ENDOGENOUS OPIOIDS |
| 690 | 1 | 0 | |a MELATONIN |
| 690 | 1 | 0 | |a NALOXONE |
| 690 | 1 | 0 | |a NOREPINEPHRINE |
| 690 | 1 | 0 | |a PINEAL GLAND |
| 690 | 1 | 0 | |a ENDORPHIN |
| 690 | 1 | 0 | |a MELATONIN |
| 690 | 1 | 0 | |a NALOXONE |
| 690 | 1 | 0 | |a NEUROTRANSMITTER |
| 690 | 1 | 0 | |a NORADRENALIN |
| 690 | 1 | 0 | |a RADIOISOTOPE |
| 690 | 1 | 0 | |a ANIMAL EXPERIMENT |
| 690 | 1 | 0 | |a CENTRAL NERVOUS SYSTEM |
| 690 | 1 | 0 | |a ENDOCRINE SYSTEM |
| 690 | 1 | 0 | |a NERVOUS SYSTEM |
| 690 | 1 | 0 | |a NONHUMAN |
| 690 | 1 | 0 | |a NORADRENALIN H 3 |
| 690 | 1 | 0 | |a PHOTOPERIODICITY |
| 690 | 1 | 0 | |a PINEAL BODY |
| 690 | 1 | 0 | |a RAT |
| 690 | 1 | 0 | |a SUBCUTANEOUS DRUG ADMINISTRATION |
| 690 | 1 | 0 | |a SYNAPSE |
| 690 | 1 | 0 | |a ANIMAL |
| 690 | 1 | 0 | |a MALE |
| 690 | 1 | 0 | |a MELATONIN |
| 690 | 1 | 0 | |a NALOXONE |
| 690 | 1 | 0 | |a PINEAL GLAND |
| 690 | 1 | 0 | |a RATS |
| 690 | 1 | 0 | |a RATS, INBRED STRAINS |
| 690 | 1 | 0 | |a SUPPORT, NON-U.S. GOV'T |
| 700 | 1 | |a Pereyra, E.N. | |
| 700 | 1 | |a Solveyra, C.G. | |
| 700 | 1 | |a Cardinali, D.P. | |
| 773 | 0 | |d 1984 |g v. 98 |h pp. 261-264 |k n. 2 |p Eur. J. Pharmacol. |x 00142999 |w (AR-BaUEN)CENRE-1772 |t European Journal of Pharmacology | |
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| 856 | 4 | 0 | |u https://doi.org/10.1016/0014-2999(84)90598-3 |y DOI |
| 856 | 4 | 0 | |u https://hdl.handle.net/20.500.12110/paper_00142999_v98_n2_p261_Lowenstein |y Handle |
| 856 | 4 | 0 | |u https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00142999_v98_n2_p261_Lowenstein |y Registro en la Biblioteca Digital |
| 961 | |a paper_00142999_v98_n2_p261_Lowenstein |b paper |c PE | ||
| 962 | |a info:eu-repo/semantics/article |a info:ar-repo/semantics/artículo |b info:eu-repo/semantics/publishedVersion | ||
| 999 | |c 79236 | ||