Estradiol -17-β enhances the formation of {3H}-PGF2α from {3H}-PGE2 in the uterus isolated from ovariectomized rats
Formation of {3H}-PGF2α and {3H}-13,14,dihydro-15-keto-PGF2α from {3H}-PGE2 by the supernatant of uterine homogenates from estrous and ovariectomized rats, was studied, using the reaction system PGE2 + NADPH + {3H}-PGE2 + supernatant. Enzymatic conversion was lower in uterine supernatants from spaye...
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| Formato: | Capítulo de libro |
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1985
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| Acceso en línea: | Registro en Scopus DOI Handle Registro en la Biblioteca Digital |
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| LEADER | 08672caa a22009977a 4500 | ||
|---|---|---|---|
| 001 | PAPER-18264 | ||
| 003 | AR-BaUEN | ||
| 005 | 20230518204937.0 | ||
| 008 | 190411s1985 xx ||||fo|||| 00| 0 eng|d | ||
| 024 | 7 | |2 scopus |a 2-s2.0-0021870996 | |
| 024 | 7 | |2 cas |a estradiol, 50-28-2; progesterone, 57-83-0; prostaglandin E2, 363-24-6; prostaglandin F2 alpha, 551-11-1; 15-keto-13,14-dihydroprostaglandin F2alpha, 27376-76-7; Dinoprost, 551-11-1; Dinoprostone, 363-24-6; Estradiol, 50-28-2; NADP, 53-59-8; Progesterone, 57-83-0; Prostaglandins E; Prostaglandins F | |
| 040 | |a Scopus |b spa |c AR-BaUEN |d AR-BaUEN | ||
| 030 | |a PRGLB | ||
| 100 | 1 | |a Franchi, A.M. | |
| 245 | 1 | 0 | |a Estradiol -17-β enhances the formation of {3H}-PGF2α from {3H}-PGE2 in the uterus isolated from ovariectomized rats |
| 260 | |c 1985 | ||
| 270 | 1 | 0 | |m Gimeno, A.L.; Centro de Estudios Farmacológicos y de Principios Naturales (CEFAPRIN), Consejo Nacional de Investigaciones Cientificas y Tecnicas de la Republica Argentina (CONICET). Serr, 1414 Buenos Aires, Argentina |
| 506 | |2 openaire |e Política editorial | ||
| 504 | |a hensby, Distribution studies on the reduction of prostaglandin E2 to prostaglandin F2α by tissue homogenates (1975) Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 409, p. 234 | ||
| 504 | |a Lee, Levine, Purification and regulatory properties of chicken heart prostaglandin E 9-keto-reductase (1975) J. Biol. Chem., 250, p. 4549 | ||
| 504 | |a Thy, Carpenter, Prostaglandin E2 9-keto-reductase of rat testis (1978) Biochem. Biophys. Res. Commun., 81, p. 322 | ||
| 504 | |a Sweatman, Collier, Effects of prostaglandins on human bronchial muscle (1968) Nature, Lond., 217, p. 69 | ||
| 504 | |a Dunn, Hood, Prostaglandins and the kidney (1977) Am. J. Physiol., 233, p. 169 | ||
| 504 | |a Phariss, Prostaglandins induction of luteolysis (1971) Annals of the New York Academy of Sciences, 180, p. 436 | ||
| 504 | |a Marsh, Lemaire, Cyclic AMP accumulation and steroidogenesis in the human corpus luteum. Effect of gonadotrophins and prostaglandins (1974) J. Clin. Endocr. Metab., 38, p. 99 | ||
| 504 | |a Channing, Stimulatory effects of prostaglandins upon luteinization of rhesus monkey granulusa cell cultures (1972) Prostaglandins, 2, p. 331 | ||
| 504 | |a Horton, Poyser, Uterine luteolytic hormone: a physiological role for prostaglandin F2α (1976) Physiol. Rev., 56, p. 595 | ||
| 504 | |a Behrman, Prostaglandins in hypothalamo-pituitary and ovarian function (1979) Ann. Rev. Physiol., 41, p. 685 | ||
| 504 | |a McCracken, The role of prostaglandins in luteal regression (1979) Prostaglandins in Fertility Control, pp. 239-258. , S. Bergström, K. Green, B. Samuelsson, W.H.O. Karolinska Institutet, Stockholm | ||
| 504 | |a Watson, Shepherd, Dodson, Prostaglandin E2 9-ketoreductase in ovarian tissues (1979) J. Reprod. Fert., 57, p. 489 | ||
| 504 | |a Del Campo, Ginther, Vascular anatomy of the uterus and ovaries and the unilateral luteolytic effect of the uterus: guinea pigs, rats, hamsters and rabbits (1972) Am. J. Vet. Res., 33, p. 2561 | ||
| 504 | |a Weems, Prostaglandins F in uterine and ovarian compartments and in plasma from uterine vein, ovarian artery and vein an abdominal aorta of pseudopregnant rats with and without deciduomata (1979) Prostaglandins, 17, p. 873 | ||
| 504 | |a Weems, Pexton, Butcher, Inskeep, Prostaglandin F in uterine tissue and venous plasma of pseudopregnant rats: effect of deciduomata (1975) Biol. Reprod., 13, p. 282 | ||
| 504 | |a Sterin-Speziale, Gimeno, Bonacossa, Gimeno, The effect of estradiol on isolated rat uterine motility and prostaglandin generation (1980) Prostaglandins, 20, p. 233 | ||
| 504 | |a Wong, Terragno, Terragno, McGiff, Dual effects of bradykinin on prostaglandin metabolism: relationship to the dissimilar vascular actions of kinins (1977) Prostaglandins, 13, p. 1113 | ||
| 504 | |a Franchi, Chaud, Borda, Gimeno, Lazzari, Gimeno, Spontaneous motility and prostaglandin generation in rat uterine horn isolated during the estrous cycle (1981) Prostaglandins, 22, p. 637 | ||
| 504 | |a Ham, Cirillo, Zanetti, Kuehl, Estrogen directed synthesis of specific prostaglandins in uterus (1975) Proc. Nat. Acad. Sci. USA, 72, p. 1420 | ||
| 504 | |a Gimeno, Sterin-Speziale, Landa, Bonacossa, Gimeno, Is the spontaneous motility of isolated rat uterus controlled by prostaglandin E? (1979) Prostaglandins, 17, p. 673 | ||
| 504 | |a Aizawa, Inazu, Kogo, Catabolism of PGF2α in rat ovary: differences between ovarian and uterine tissues (1980) Prostaglandins, 20, p. 95 | ||
| 504 | |a Anggard, Larsson, Samuelsson, The distribution of 15-hydroxy prostaglandin dehydrogenase and prostaglandin Δ13-reductase in tissues of swine (1971) Acta Physiologica Scandinavica, 81, p. 396 | ||
| 504 | |a Alam, Russell, Tabor, Moulton, Progesterone and estrogen control of uterine dehydrogenase activity during deciduonal growth (1976) Endocrinology, 98, p. 859 | ||
| 504 | |a Blackwell, Flower, Effect of steroid hormones on tissue levels of prostaglandin 15-hydroxy-dehydrogenase in the rat (1976) Br. J. Pharmac., 56, p. 343 | ||
| 504 | |a Kogo, Yamada, Aizawa, Effect of estradiol on prostaglandin metabolism in rat uterus (1977) Prostaglandins, 13, p. 785 | ||
| 504 | |a Auleta, Agins, Scommegna, Prostaglandin F mediation of the inhibitory effect of estrogen on the corpus luteum of the rhesus monkey (1978) Endocrinology, 103, p. 1183 | ||
| 504 | |a Thaler-Dao, Saintot, Ramonatxo, Chavis, Crastes de, Prostaglandin biosynthesis by the rat uterus during the oestrus cycle: Temporal correlation with plasma oestradiol and progesterone concentrations, identification of 6-keto PGF1α as the major metabolite (1982) Prostaglandins, 23, p. 347 | ||
| 520 | 3 | |a Formation of {3H}-PGF2α and {3H}-13,14,dihydro-15-keto-PGF2α from {3H}-PGE2 by the supernatant of uterine homogenates from estrous and ovariectomized rats, was studied, using the reaction system PGE2 + NADPH + {3H}-PGE2 + supernatant. Enzymatic conversion was lower in uterine supernatants from spayed rats than in uterine homogenates of rats at natural estrus. Spayed animals were injected with progesterone (P) or with estradiol-17-β (E0) at a dose of 1.0 or 50.0 ug. Conversion of {3H}-PGF2α to {3H}-PGE2 or to {3H}-13,14,dihydro-15-keto-PGF2α did not differ in control ovariectomized or ovariectomized rats receiving P or 1.0 ug E0. However, 50.0 ug E0 induced a significant oversion after 30 (P < 0.01) and 60 (P < 0.001) min of incubation. It is concluded that E0, at the 50.0 ug dose, but not the 1.0 ug dose of E0, nor progesterone, stimulated conversion of {3H}-PGE2 into {3H}-PGF2α or {3H}-13, 14,dihydro-15-keto-PGF2α, presumably through the activity of the enzyme PGE2-9-keto-reductase. © 1985. |l eng | |
| 593 | |a Centro de Estudios Farmacológicos y de Principios Naturales (CEFAPRIN), Consejo Nacional de Investigaciones Cientificas y Tecnicas de la Republica Argentina (CONICET). Serr, 1414 Buenos Aires, Argentina | ||
| 690 | 1 | 0 | |a ESTRADIOL |
| 690 | 1 | 0 | |a PROGESTERONE |
| 690 | 1 | 0 | |a PROSTAGLANDIN E2 |
| 690 | 1 | 0 | |a PROSTAGLANDIN F2 ALPHA |
| 690 | 1 | 0 | |a RADIOISOTOPE |
| 690 | 1 | 0 | |a ANIMAL CELL |
| 690 | 1 | 0 | |a DRUG EFFICACY |
| 690 | 1 | 0 | |a ENDOCRINE SYSTEM |
| 690 | 1 | 0 | |a FEMALE GENITAL SYSTEM |
| 690 | 1 | 0 | |a MYOMETRIUM |
| 690 | 1 | 0 | |a NONHUMAN |
| 690 | 1 | 0 | |a OVARIECTOMY |
| 690 | 1 | 0 | |a PRIORITY JOURNAL |
| 690 | 1 | 0 | |a PROSTAGLANDIN E2 H 3 |
| 690 | 1 | 0 | |a RAT |
| 690 | 1 | 0 | |a ANIMAL |
| 690 | 1 | 0 | |a CASTRATION |
| 690 | 1 | 0 | |a DINOPROST |
| 690 | 1 | 0 | |a DINOPROSTONE |
| 690 | 1 | 0 | |a ESTRADIOL |
| 690 | 1 | 0 | |a FEMALE |
| 690 | 1 | 0 | |a NADP |
| 690 | 1 | 0 | |a PROGESTERONE |
| 690 | 1 | 0 | |a PROSTAGLANDINS E |
| 690 | 1 | 0 | |a PROSTAGLANDINS F |
| 690 | 1 | 0 | |a RATS |
| 690 | 1 | 0 | |a RATS, INBRED STRAINS |
| 690 | 1 | 0 | |a SUPPORT, NON-U.S. GOV'T |
| 690 | 1 | 0 | |a UTERUS |
| 700 | 1 | |a Gimeno, M.F. | |
| 700 | 1 | |a Gimeno, A.L. | |
| 773 | 0 | |d 1985 |g v. 29 |h pp. 773-783 |k n. 5 |p Prostaglandins |x 00906980 |t Prostaglandins | |
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| 856 | 4 | 0 | |u https://doi.org/10.1016/0090-6980(85)90137-6 |y DOI |
| 856 | 4 | 0 | |u https://hdl.handle.net/20.500.12110/paper_00906980_v29_n5_p773_Franchi |y Handle |
| 856 | 4 | 0 | |u https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00906980_v29_n5_p773_Franchi |y Registro en la Biblioteca Digital |
| 961 | |a paper_00906980_v29_n5_p773_Franchi |b paper |c PE | ||
| 962 | |a info:eu-repo/semantics/article |a info:ar-repo/semantics/artículo |b info:eu-repo/semantics/publishedVersion | ||
| 999 | |c 79217 | ||