Characterization of a sexual steroid binding protein in Bufo arenarum

Reproductively active female Bufo arenarum possess a serum protein (SBP) that binds testosterone, dihydrotestosterone, and estradiol with high affinity and capacity. The binding capacity values are two orders of magnitude higher than those found in human serum. The specificity of B. arenarum SBP is...

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Autor principal: Santa-Coloma, T.A
Otros Autores: Fernandez, S., Charreau, E.H
Formato: Capítulo de libro
Lenguaje:Inglés
Publicado: 1985
Acceso en línea:Registro en Scopus
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005 20230518204937.0
008 190411s1985 xx ||||fo|||| 00| 0 eng|d
024 7 |2 scopus  |a 2-s2.0-0022387084 
024 7 |2 cas  |a androstanolone, 521-18-6; estradiol, 50-28-2; metribolone, 965-93-5; testosterone, 58-22-0; Estradiol, 50-28-2; Sex Hormone-Binding Globulin; Stanolone, 521-18-6; Testosterone, 57-85-2 
040 |a Scopus  |b spa  |c AR-BaUEN  |d AR-BaUEN 
030 |a GCENA 
100 1 |a Santa-Coloma, T.A. 
245 1 0 |a Characterization of a sexual steroid binding protein in Bufo arenarum 
260 |c 1985 
270 1 0 |m Santa-Coloma, T.A.; Instituto de Biología y Medicina Experimental, Obligado 2490, Buenos Aires, 1428, Argentina 
506 |2 openaire  |e Política editorial 
504 |a Ackers, Analytical gel chomatography of proteins (1970) Adv. Protein Chem, 24, pp. 343-446 
504 |a Bardin, Musto, Gunsalus, Kotite, Cheng, Larrea, Becker, Extracellular androgen binding proteins (1981) Annu. Rev. Physiol, 43, pp. 189-198 
504 |a Belgorosky, Rivarola, Sex hormone-binding globulin response to human chorionic gonadotropin stimulation in children with cryptorchidism, anorchia, male pseudo hermaphroditism, and micropenis (1982) J. Clin. Endocrinol. Metab, 54, pp. 698-704 
504 |a Bonne, Raynaud, Methyltrienolone, a specific ligand for cellular androgen receptor (1975) Steroids, 26, pp. 227-232 
504 |a Burns, Rose, Testosterone, estrogen binding protein in sexually mature larvae of Ambystoma tigrinum (1980) Gen. Comp. Endocrinol, 41, pp. 314-320 
504 |a Corvol, Bardin, Species distribution of testosterone-binding globulin (1973) Biol. Reprod, 8, pp. 277-282 
504 |a Davis, Disc electrophoresis. II. Method and application to human serum proteins (1964) Ann. N.Y. Acad. Sci, 121, pp. 404-427 
504 |a Fernandez, Tesone, Miceli, Charreau, (1981) Proceedings, XVII Meeting of the Argentine Society of Biochemical Investigation, , Cordoba, Argentina, Abstract 153 
504 |a Laurent, Killander, A theory of gel filtration and its experimental verification (1964) Journal of Chromatography A, 14, pp. 317-330 
504 |a Martin, Ames, A method for determinating the sedimentation behavior of enzymes: Application to protein mixtures (1961) J. Biol. Chem, 236, pp. 1372-1379 
504 |a Martin, Ozon, Boffa, Liaison des steroides sexuelles aux proteines seriques chez l'Amphibien urodele: Pleurodeles waltii. Influence du sexe (1971) C.R. Acad. Sci. Paris, 272, pp. 1413-1416 
504 |a Martin, Ozon, Steroid protein interaction in nonmammalian vertebrates. II. Steroid binding proteins in the serum of Amphibians: A physiological approach (1975) Biol. Reprod, 13, pp. 371-380 
504 |a Moore, Spielvogel, Zoeller, Wingfield, Testosterone-binding protein in a seasonally breeding amphibian (1983) Gen. Comp. Endocrinol, 49, pp. 15-21 
504 |a Ritzen, French, Weddington, Nayfeh, Hansson, Steroid binding in polyacrylamide gel. Quantitation at steady-state conditions (1974) J. Biol. Chem, 249, pp. 6597-6604 
504 |a Rodbard, Peter, Munson, Thakur, Quantitative characterization of hormone receptors (1980) Cancer, 46, pp. 2907-2918 
504 |a Salhanick, Callard, A sexsteroid binding protein in the plasma of the freshwater turtle, Chrysemys picta (1980) Gen. Comp. Endocrinol, 42, pp. 163-166 
504 |a Schachman, (1959) Ultracentrifugation in Biochemistry, p. 239. , Academic Press, New York 
504 |a Siegel, Monty, Determination of molecular weight and frictional ratios of proteins in impure systems by use of gel filtration and density gradient centrifugation. Application to crude preparations of sulfite and hydroxylamine reductases (1966) Biochim. Biophys. Acta, 112, pp. 346-362 
504 |a Svedberg, Pedersen, (1940) The Ultracentrifuge, p. 41. , Oxford Univ. Press, London/New York, Johnson Reprint Corporation, New York 
504 |a Tandford, (1961) Physical Chemistry of Macromolecules, p. 356. , Wiley, New York 
520 3 |a Reproductively active female Bufo arenarum possess a serum protein (SBP) that binds testosterone, dihydrotestosterone, and estradiol with high affinity and capacity. The binding capacity values are two orders of magnitude higher than those found in human serum. The specificity of B. arenarum SBP is comparable to human SBP with the exception that it has a high affinity for the synthetic androgen methyltrienolone (R1881). The physicochemical characterization of SBP indicates a Stokes radius of 43.5 Å, a sedimentation coefficient of 5.2 S, and a molecular weight of 93,300. © 1985.  |l eng 
593 |a Instituto de Biología y Medicina Experimental, Obligado 2490, Buenos Aires, 1428, Argentina 
593 |a Instituto Superior de Investigaciones Biológicas, Tucumán, Argentina 
690 1 0 |a ANDROSTANOLONE 
690 1 0 |a ESTRADIOL 
690 1 0 |a METRIBOLONE 
690 1 0 |a SEX HORMONE BINDING PROTEIN 
690 1 0 |a TESTOSTERONE 
690 1 0 |a ENDOCRINE SYSTEM 
690 1 0 |a FEMALE GENITAL SYSTEM 
690 1 0 |a MALE GENITAL SYSTEM 
690 1 0 |a METHODOLOGY 
690 1 0 |a MOLECULAR WEIGHT 
690 1 0 |a NONHUMAN 
690 1 0 |a PRIORITY JOURNAL 
690 1 0 |a SEDIMENTATION COEFFICIENT 
690 1 0 |a ANIMAL 
690 1 0 |a BUFO ARENARUM 
690 1 0 |a ELECTROPHORESIS, POLYACRYLAMIDE GEL 
690 1 0 |a ESTRADIOL 
690 1 0 |a KINETICS 
690 1 0 |a SEX HORMONE-BINDING GLOBULIN 
690 1 0 |a STANOLONE 
690 1 0 |a SUBSTRATE SPECIFICITY 
690 1 0 |a TESTOSTERONE 
700 1 |a Fernandez, S. 
700 1 |a Charreau, E.H. 
773 0 |d 1985  |g v. 60  |h pp. 273-279  |k n. 2  |p Gen. Comp. Endocrinol.  |x 00166480  |w (AR-BaUEN)CENRE-4807  |t General and Comparative Endocrinology 
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856 4 0 |u https://doi.org/10.1016/0016-6480(85)90324-7  |y DOI 
856 4 0 |u https://hdl.handle.net/20.500.12110/paper_00166480_v60_n2_p273_SantaColoma  |y Handle 
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